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1
المؤلفون: Joel M. Harris, Xiaoping Zhou, John A. Morrow, Sue-Ing Lin, Marco A. S. Baptista, John M. Sanders, Xiaoping Zhang, Hong Mei, Mark W. Embrey, Sylvie M. Sur, Duane E. DeMong, Ravi P. Nargund, Alan Hruza, Heather E. Tiscia, Matthew J. Fell, Zhizhang Yin, Gautam Agnihotri, Honglu Zhang, Thomas J. Greshock, Jack D. Scott, Yinghui Lin, Zhi-Cai Shi, John A. Mccauley, Sarah W. Li, Ronald K. Chang, Mark T. Bilodeau, Michael W. Miller, Reshma Kuvelkar, Andrew Stamford, Marc Poirier, Hong Liu, Megan K. Macala, Kallol Basu, Li Xiao, Lynn A. Hyde, Jonathan T. Kern, Xing Dai, Christian Mirescu, Paul L. Walsh, Matthew E. Kennedy, John J. Renger, Zhiyong Hu, John Columbus, Robert E. Drolet, Eric M. Parker
المصدر: Journal of medicinal chemistry. 60(7)
مصطلحات موضوعية: 0301 basic medicine, Male, Indazoles, Leucine-rich repeat, Leucine-Rich Repeat Serine-Threonine Protein Kinase-2, 03 medical and health sciences, 0302 clinical medicine, Drug Discovery, Animals, Humans, c-Raf, Kinase activity, Enzyme Inhibitors, Rats, Wistar, biology, Cyclin-dependent kinase 4, Kinase, Chemistry, Cyclin-dependent kinase 2, Brain, Parkinson Disease, LRRK2, nervous system diseases, Rats, Molecular Docking Simulation, 030104 developmental biology, Protein kinase domain, Biochemistry, biology.protein, Molecular Medicine, 030217 neurology & neurosurgery
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2
المؤلفون: Jean E. Lachowicz, Kung-I Feng, Joyce J. Hwa, Jitendra D. Belani, Michael Wong, Ling Kang, Diane Grotz, Wensheng Yu, Sue-Ing Lin, Yang Cao, Andrew Stamford, Richard A. Morrison, Peishan Lin, Duane E. DeMong, Hongtao Zhang, Peng Dai, Jolicia Gauuan, Christopher Sondey, Joseph A. Kozlowski, He Zhao, Mark Liang, Ying Zhai, Brian J. Lavey, Xing Dai, Aileen Soriano, Tao Meng, Ping Chen, De-Yi Yang, William J. Greenlee, Bradley Prudence K, Kathleen Cox, Bhuneshwari Patel, Paul McNamara, Jesse K. Wong, Michael W. Miller, Guowei Zhou, Teresa Andreani
المصدر: Journal of Medicinal Chemistry. 57:2601-2610
مصطلحات موضوعية: Tert butyl, medicine.medical_specialty, Chemistry, Antagonist, Pharmacology, chemistry.chemical_compound, Endocrinology, Oral administration, Internal medicine, Pharmacodynamics, Drug Discovery, medicine, Molecular Medicine, Selectivity, Benzamide, Receptor, Glucagon receptor
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3
المؤلفون: Tony Priestley, Vaccaro Henry A, Andrew Stamford, Deborra E Mullins, Michael W. Miller, Tin-Yau Chan, Robert A. Hodgson, Scott Jack D, William J. Greenlee, Liwu Hong, Mario Guzzi, Sarah W. Li, Eric M. Parker, Geoffrey B. Varty, Jay Weinstein, Sue-Ing Lin, Mckittrick Brian A
المصدر: Bioorganic & Medicinal Chemistry Letters. 19:6018-6022
مصطلحات موضوعية: Receptors, Vasopressin, Vasopressin, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Biochemistry, Structure-Activity Relationship, chemistry.chemical_compound, Drug Discovery, Animals, Humans, Receptor, Molecular Biology, chemistry.chemical_classification, Arginine vasopressin receptor 1B, Sulfonamides, Tetrahydroisoquinoline, Antidiuretic Agents, Organic Chemistry, Antagonist, Rats, Sulfonamide, chemistry, Receptors, Oxytocin, Quinolines, Molecular Medicine, Piperidine, Linker, Antidiuretic Hormone Receptor Antagonists
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4
المؤلفون: Duane, DeMong, Xing, Dai, Joyce, Hwa, Michael, Miller, Sue-Ing, Lin, Ling, Kang, Andrew, Stamford, William, Greenlee, Wensheng, Yu, Michael, Wong, Brian, Lavey, Joseph, Kozlowski, Guowei, Zhou, De-Yi, Yang, Bhuneshwari, Patel, Aileen, Soriano, Ying, Zhai, Christopher, Sondey, Hongtao, Zhang, Jean, Lachowicz, Diane, Grotz, Kathleen, Cox, Richard, Morrison, Teresa, Andreani, Yang, Cao, Mark, Liang, Tao, Meng, Paul, McNamara, Jesse, Wong, Prudence, Bradley, Kung-I, Feng, Jitendra, Belani, Ping, Chen, Peng, Dai, Jolicia, Gauuan, Peishan, Lin, He, Zhao
المصدر: Journal of medicinal chemistry. 57(6)
مصطلحات موضوعية: Blood Glucose, Mice, Inbred ICR, Cyclohexanones, Diet, High-Fat, Glucagon, Diabetes Mellitus, Experimental, Prediabetic State, Mice, Structure-Activity Relationship, Diabetes Mellitus, Type 2, Benzamides, Drug Discovery, Receptors, Glucagon, Animals, Spiro Compounds, Obesity
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5
المؤلفون: Michael G. Murray, Bernard R. Neustadt, Julie M. Strizki, Sue-Ing Lin, Nicole Vantuno, Lisa Wojcik, Jayaram R. Tagat, Kathleen Cox, and Bahige M. Baroudy, Steensma Ruo, Dennis V. Nazareno, Stuart W. McCombie, Serena Xu
المصدر: Journal of Medicinal Chemistry. 44:3343-3346
مصطلحات موضوعية: Chemistry, Stereochemistry, Antagonist, virus diseases, CCR5 receptor antagonist, Chemical synthesis, Bioavailability, chemistry.chemical_compound, Piperazine, Drug Discovery, Muscarinic acetylcholine receptor, Molecular Medicine, Structure–activity relationship, Piperidine
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6
المؤلفون: Dennis V. Nazareno, Stuart W. McCombie, Bahige M. Baroudy, Jayaram R. Tagat, Steensma Ruo, Serena Xu, Sue-Ing Lin, Nicole Vantuno, Jia Liu
المصدر: Bioorganic & Medicinal Chemistry Letters. 11:2143-2146
مصطلحات موضوعية: Anti-HIV Agents, Stereochemistry, medicine.drug_class, Clinical Biochemistry, Pharmaceutical Science, Carboxamide, Microbial Sensitivity Tests, CCR5 receptor antagonist, Biochemistry, Piperazines, Structure-Activity Relationship, chemistry.chemical_compound, Drug Discovery, medicine, Structure–activity relationship, Benzamide, Molecular Biology, Chemistry, Ligand binding assay, Organic Chemistry, Piperazine, CCR5 Receptor Antagonists, HIV-1, Molecular Medicine, Piperidine, Pharmacophore
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7
المؤلفون: Kirkup Michael P, Bandarpalle B. Shankar, John W. Clader, Keith Huie, Sue-Ing Lin, Harry R. Davis, Douglas S Compton, Stuart W. McCombie, Andrew T. McPhail, Margaret van Heek, Yumibe Nathan P, Razia Rizvi, Sundeep Dugar
المصدر: Bioorganic & Medicinal Chemistry Letters. 6:2069-2072
مصطلحات موضوعية: Stereochemistry, Chemistry, medicine.drug_class, Organic Chemistry, Clinical Biochemistry, Pharmaceutical Science, Metabolic stability, Biochemistry, Drug Discovery, Side chain, medicine, Molecular Medicine, Potency, Cholesterol absorption inhibitor, Molecular Biology
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8
المؤلفون: Mark E. Snow, Sue-Ing Lin, Stuart W. McCombie, Harry R. Davis, Sundeep Dugar, Kirkup Michael P, John W. Clader, Razia Rizvi
المصدر: Bioorganic & Medicinal Chemistry Letters. 5:2947-2952
مصطلحات موضوعية: medicine.drug_class, Stereochemistry, Organic Chemistry, Clinical Biochemistry, Pharmaceutical Science, biochemical phenomena, metabolism, and nutrition, Ring (chemistry), Biochemistry, Beta-lactam, chemistry.chemical_compound, chemistry, Drug Discovery, polycyclic compounds, Homologous chromosome, medicine, Molecular Medicine, Structure–activity relationship, Cholesterol absorption inhibitor, Molecular Biology, SCH-48461, Cholesterol absorption
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9
المؤلفون: Stuart W. McCombie, Oswald Wilson, Kirkup Michael P, Karen Rosinski, Sue-Ing Lin, Robert Bishop, Bandarpalle B. Shankar, Paul Kirschmeier, Emily Dobek, Joanne M. Petrin, Donna Carr
المصدر: Bioorganic & Medicinal Chemistry Letters. 3:1537-1542
مصطلحات موضوعية: chemistry.chemical_classification, biology, Chemistry, Stereochemistry, Organic Chemistry, Clinical Biochemistry, Pharmaceutical Science, Thio, Total synthesis, Condensation reaction, Biochemistry, Enzyme, Thiolysis, Enzyme inhibitor, Drug Discovery, biology.protein, Molecular Medicine, Protein kinase A, Molecular Biology, Protein kinase C
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10
المؤلفون: Sue Ing Lin, Stuart W. McCombie, Jayaram R. Tagat
المصدر: ChemInform. 24
مصطلحات موضوعية: chemistry.chemical_compound, Nalidixic acid, chemistry, Pyridine, medicine, chemistry.chemical_element, Organic chemistry, General Medicine, Oxygen, Sulfur, medicine.drug