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المؤلفون: Chris Tse, Charles Brenner, Saul H. Rosenberg, Wenqing Gao, Gary G. Chiang, F. Gregory Buchanan, David Maag, Michael R. Michaelides, Michael L. Curtin, Ilaria Badagnani, Shaun M. McLoughlin, Paul L. Richardson, Hua Tang, Vivek C. Abraham, Danli L. Towne, Steven Cepa, Alla V. Korepanova, Diana Raich, Kenton L. Longenecker, T. Matthew Hansen, Richard F. Clark, Bryan K. Sorensen, H. Robin Heyman, Sujatha Selvaraju, Yupeng He, Peter J. Kovar, Stormy L. Koeniger, Jun Guo, Yan Shi, Samuel A.J. Trammell, Dong Cheng, Min Cheng, Julie L. Wilsbacher
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f450290df0d613596edbab94a5a07a69
https://doi.org/10.1158/1535-7163.22503433.v1 -
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المؤلفون: Chris Tse, Charles Brenner, Saul H. Rosenberg, Wenqing Gao, Gary G. Chiang, F. Gregory Buchanan, David Maag, Michael R. Michaelides, Michael L. Curtin, Ilaria Badagnani, Shaun M. McLoughlin, Paul L. Richardson, Hua Tang, Vivek C. Abraham, Danli L. Towne, Steven Cepa, Alla V. Korepanova, Diana Raich, Kenton L. Longenecker, T. Matthew Hansen, Richard F. Clark, Bryan K. Sorensen, H. Robin Heyman, Sujatha Selvaraju, Yupeng He, Peter J. Kovar, Stormy L. Koeniger, Jun Guo, Yan Shi, Samuel A.J. Trammell, Dong Cheng, Min Cheng, Julie L. Wilsbacher
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34e7619544c11452e1775f6d92101867
https://doi.org/10.1158/1535-7163.22503430.v1 -
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المؤلفون: Kathy Sarris, Ying Wang, Gary G. Chiang, Yupeng He, Mikkel Algire, Ramzi F. Sweis, Huan-Qiu Li, Marina A. Pliushchev, Zhiqin Ji, Paul L. Richardson, Maricel Torrent, Bailin Shaw, Richard F. Clark, Michael L. Curtin, Justin D. Dietrich, Clarissa G. Jakob, Chaohong Sun, Sujatha Selvaraju, Haizhong Zhu, Hongyu Zhao, Michael R. Michaelides
المصدر: Bioorganic & Medicinal Chemistry Letters. 27:1576-1583
مصطلحات موضوعية: 0301 basic medicine, Pyrrolidines, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Antineoplastic Agents, Stereoisomerism, macromolecular substances, Plasma protein binding, Ligands, Biochemistry, Mice, Structure-Activity Relationship, 03 medical and health sciences, 0302 clinical medicine, Mouse xenograft, Cell Line, Tumor, Drug Discovery, Animals, Humans, Structure–activity relationship, PRC2 complex, Molecular Biology, Indole test, Sulfonamides, biology, Novel protein, Chemistry, Organic Chemistry, Polycomb Repressive Complex 2, Xenograft Model Antitumor Assays, 030104 developmental biology, 030220 oncology & carcinogenesis, Microsomes, Liver, biology.protein, Molecular Medicine, PRC2, Protein Binding
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المؤلفون: Alla Korepanova, Danli L. Towne, F. Gregory Buchanan, Jun Guo, Stormy L. Koeniger, Diana Raich, Yan Shi, Michael L. Curtin, Gary G. Chiang, Bryan K. Sorensen, Yupeng He, Hua Tang, Vivek C. Abraham, H. Robin Heyman, Richard F. Clark, Kenton L. Longenecker, Saul H. Rosenberg, Paul L. Richardson, Badagnani Ilaria, Wenqing Gao, Julie L. Wilsbacher, Peter Kovar, David Maag, Samuel A.J. Trammell, Dong Cheng, T. Matthew Hansen, Shaun M. McLoughlin, Chris Tse, Min Cheng, Steven Cepa, Michael R. Michaelides, Sujatha Selvaraju, Charles Brenner
المصدر: Molecular cancer therapeutics. 16(7)
مصطلحات موضوعية: 0301 basic medicine, Cancer Research, DNA Repair, Nicotinamide phosphoribosyltransferase, 03 medical and health sciences, chemistry.chemical_compound, Enzyme activator, Mice, 0302 clinical medicine, Adenosine Triphosphate, In vivo, Animals, Humans, Calcium Signaling, Enzyme Inhibitors, Nicotinamide Phosphoribosyltransferase, chemistry.chemical_classification, Nicotinamide, Chemistry, HCT116 Cells, NAD, Xenograft Model Antitumor Assays, Enzyme Activation, Gene Expression Regulation, Neoplastic, 030104 developmental biology, Enzyme, Oncology, Biochemistry, 030220 oncology & carcinogenesis, Cancer cell, Cytokines, NAD+ kinase, Colorectal Neoplasms, Adenosine triphosphate
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52767e3106bf204068387e3e1747ff90
https://pubmed.ncbi.nlm.nih.gov/28468779 -
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المؤلفون: Kenneth M. Comess, Steven Kennedy, Donald J. Osterling, Michael L. Curtin, Masoud Vedadi, Ramzi F. Sweis, Guillermo Senisterra, Mikkel Algire, Evelyne Lima-Fernandes, Dalia Barsyte-Lovejoy, Justin D. Dietrich, William N. Pappano, Bailin Shaw, David Maag, Dong Cheng, Cheryl H. Arrowsmith, Fengling Li, Marina A. Pliushchev, Kelly L Klinge, Jun Guo, Chaohong Sun, Andrew M. Petros, Gary G. Chiang, Magdalena M. Szewczyk, Huan-Qiu Li, Maricel Torrent, Scott Galasinski, Sujatha Selvaraju, Yupeng He, David Lindley, Clarissa G. Jakob, Sanjay C. Panchal, Wenqing Gao, Lance J Bigelow, Haizhong Zhu, Fritz G. Buchanan, Qin Wu
المصدر: Nature chemical biology. 13(4)
مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, Cell Survival, Protein subunit, Allosteric regulation, Antineoplastic Agents, macromolecular substances, Protein–protein interaction, 03 medical and health sciences, Histone H3, Structure-Activity Relationship, 0302 clinical medicine, Cell Line, Tumor, Tumor Cells, Cultured, Gene silencing, Humans, Epigenetics, Molecular Biology, Cell Proliferation, chemistry.chemical_classification, Sulfonamides, biology, Dose-Response Relationship, Drug, Molecular Structure, Polycomb Repressive Complex 2, Cell Biology, 030104 developmental biology, Enzyme, Biochemistry, chemistry, 030220 oncology & carcinogenesis, Indans, biology.protein, Drug Screening Assays, Antitumor, PRC2, Protein Binding
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المؤلفون: Yupeng, He, Sujatha, Selvaraju, Michael L, Curtin, Clarissa G, Jakob, Haizhong, Zhu, Kenneth M, Comess, Bailin, Shaw, Juliana, The, Evelyne, Lima-Fernandes, Magdalena M, Szewczyk, Dong, Cheng, Kelly L, Klinge, Huan-Qiu, Li, Marina, Pliushchev, Mikkel A, Algire, David, Maag, Jun, Guo, Justin, Dietrich, Sanjay C, Panchal, Andrew M, Petros, Ramzi F, Sweis, Maricel, Torrent, Lance J, Bigelow, Guillermo, Senisterra, Fengling, Li, Steven, Kennedy, Qin, Wu, Donald J, Osterling, David J, Lindley, Wenqing, Gao, Scott, Galasinski, Dalia, Barsyte-Lovejoy, Masoud, Vedadi, Fritz G, Buchanan, Cheryl H, Arrowsmith, Gary G, Chiang, Chaohong, Sun, William N, Pappano
المصدر: Nature Chemical Biology. 13:922-922
مصطلحات موضوعية: Cell Biology, Molecular Biology