المؤلفون: Han KS; Department of Chemical & Biomolecular Engineering, Johns Hopkins University, Baltimore, MD.; The Johns Hopkins Institute for NanoBioTechnology, Johns Hopkins University, Baltimore, MD., Sander IB; Department of Dermatology, Johns Hopkins University, Baltimore, MD., Kumer J; Department of Illustration Practice, Maryland Institute College of Art, Baltimore, MD., Resnick E; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD., Booth C; Center for Cancer Research, National Cancer Institute, Frederick, MD., Cheng G; Department of Chemical & Biomolecular Engineering, Johns Hopkins University, Baltimore, MD.; The Johns Hopkins Institute for NanoBioTechnology, Johns Hopkins University, Baltimore, MD., Im Y; Department of Chemical & Biomolecular Engineering, Johns Hopkins University, Baltimore, MD.; The Johns Hopkins Institute for NanoBioTechnology, Johns Hopkins University, Baltimore, MD., Starich B; Department of Chemical & Biomolecular Engineering, Johns Hopkins University, Baltimore, MD.; The Johns Hopkins Institute for NanoBioTechnology, Johns Hopkins University, Baltimore, MD., Kiemen AL; Department of Pathology, Johns Hopkins School of Medicine, Baltimore, MD., Phillip JM; Department of Chemical & Biomolecular Engineering, Johns Hopkins University, Baltimore, MD.; The Johns Hopkins Institute for NanoBioTechnology, Johns Hopkins University, Baltimore, MD.; Department of Biomedical Engineering, Johns Hopkins School of Medicine, Baltimore, MD.; Department of Oncology, Johns Hopkins School of Medicine, Baltimore, MD., Reddy S; The Johns Hopkins Institute for NanoBioTechnology, Johns Hopkins University, Baltimore, MD.; Department of Plastic and Reconstructive Surgery, Johns Hopkins School of Medicine, Baltimore, MD., Joshu CE; Department of Epidemiology, Johns Hopkins School of Public Health, Baltimore, MD., Sunshine JC; Department of Dermatology, Johns Hopkins University, Baltimore, MD., Walston JD; Department of Medicine, Division of Geriatrics and Gerontology, Johns Hopkins School of Medicine, Baltimore, MD., Wirtz D; Department of Chemical & Biomolecular Engineering, Johns Hopkins University, Baltimore, MD.; The Johns Hopkins Institute for NanoBioTechnology, Johns Hopkins University, Baltimore, MD.; Department of Oncology, Johns Hopkins School of Medicine, Baltimore, MD., Wu PH; Department of Chemical & Biomolecular Engineering, Johns Hopkins University, Baltimore, MD.; The Johns Hopkins Institute for NanoBioTechnology, Johns Hopkins University, Baltimore, MD.

المصدر: BioRxiv : the preprint server for biology [bioRxiv] 2024 Jul 06. Date of Electronic Publication: 2024 Jul 06.

نوع المنشور: Journal Article; Preprint

بيانات الدورية: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

المؤلفون: Luly KM; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland 21205, United States.; Translational Tissue Engineering Center, Johns Hopkins University School of Medicine, Baltimore, Maryland 21231, United States., Green JJ; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland 21205, United States.; Translational Tissue Engineering Center, Johns Hopkins University School of Medicine, Baltimore, Maryland 21231, United States.; Institute for Nanobiotechnology, Johns Hopkins University, Baltimore, Maryland 21218, United States.; Bloomberg∼Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine, Baltimore, Maryland 21231, United States.; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland 21231, United States.; Departments of Neurosurgery, Ophthalmology, and Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21231, United States.; Departments of Materials Science & Engineering and Chemical & Biomolecular Engineering, Johns Hopkins University, Baltimore, Maryland 21218, United States., Sunshine JC; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland 21205, United States.; Departments of Dermatology and Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, United States., Tzeng SY; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland 21205, United States.; Translational Tissue Engineering Center, Johns Hopkins University School of Medicine, Baltimore, Maryland 21231, United States.

المصدر: ACS biomaterials science & engineering [ACS Biomater Sci Eng] 2023 Nov 13; Vol. 9 (11), pp. 6438-6450. Date of Electronic Publication: 2023 Oct 05.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101654670 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2373-9878 (Electronic) Linking ISSN: 23739878 NLM ISO Abbreviation: ACS Biomater Sci Eng Subsets: MEDLINE

مواضيع طبية MeSH: Carcinoma, Merkel Cell*/genetics , Carcinoma, Merkel Cell*/drug therapy , Skin Neoplasms*/genetics , Skin Neoplasms*/therapy , Melanoma*/genetics , Melanoma*/therapy, Animals ; Mice ; Humans ; DNA/therapeutic use ; Interleukin-12/therapeutic use ; Cell Death ; Tumor Microenvironment/genetics

المؤلفون: Madan V; Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Marchitto MC; Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Sunshine JC; Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.

المصدر: Dermatopathology (Basel, Switzerland) [Dermatopathology (Basel)] 2023 Aug 15; Vol. 10 (3), pp. 244-258. Date of Electronic Publication: 2023 Aug 15.

نوع المنشور: Case Reports

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101651125 Publication Model: Electronic Cited Medium: Print ISSN: 2296-3529 (Print) Linking ISSN: 22963529 NLM ISO Abbreviation: Dermatopathology (Basel) Subsets: PubMed not MEDLINE

المؤلفون: Doyle J; Department of Astronomy and Physics, Johns Hopkins University, Baltimore, Maryland., Green BF; Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, Maryland; The Mark Foundation Center for Advanced Genomics and Imaging, Johns Hopkins University, Baltimore, Maryland; Bloomberg∼Kimmel Institute for Cancer Immunotherapy and Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, Maryland., Eminizer M; Department of Astronomy and Physics, Johns Hopkins University, Baltimore, Maryland; Institute for Data Intensive Engineering and Science, Johns Hopkins University, Baltimore, Maryland., Jimenez-Sanchez D; Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, Maryland., Lu S; Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, Maryland., Engle EL; Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, Maryland; The Mark Foundation Center for Advanced Genomics and Imaging, Johns Hopkins University, Baltimore, Maryland; Bloomberg∼Kimmel Institute for Cancer Immunotherapy and Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, Maryland., Xu H; Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, Maryland; The Mark Foundation Center for Advanced Genomics and Imaging, Johns Hopkins University, Baltimore, Maryland; Bloomberg∼Kimmel Institute for Cancer Immunotherapy and Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, Maryland., Ogurtsova A; Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, Maryland; The Mark Foundation Center for Advanced Genomics and Imaging, Johns Hopkins University, Baltimore, Maryland; Bloomberg∼Kimmel Institute for Cancer Immunotherapy and Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, Maryland., Lai J; Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, Maryland., Soto-Diaz S; Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, Maryland., Roskes JS; Department of Astronomy and Physics, Johns Hopkins University, Baltimore, Maryland; Institute for Data Intensive Engineering and Science, Johns Hopkins University, Baltimore, Maryland., Deutsch JS; Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, Maryland., Taube JM; Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, Maryland; The Mark Foundation Center for Advanced Genomics and Imaging, Johns Hopkins University, Baltimore, Maryland; Bloomberg∼Kimmel Institute for Cancer Immunotherapy and Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, Maryland; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland., Sunshine JC; Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, Maryland; Bloomberg∼Kimmel Institute for Cancer Immunotherapy and Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, Maryland; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland; Johns Hopkins Center for Translational Immunoengineering, Johns Hopkins University School of Medicine, Baltimore, Maryland. Electronic address: joelsunshine@jhmi.edu., Szalay AS; Department of Astronomy and Physics, Johns Hopkins University, Baltimore, Maryland; The Mark Foundation Center for Advanced Genomics and Imaging, Johns Hopkins University, Baltimore, Maryland; Institute for Data Intensive Engineering and Science, Johns Hopkins University, Baltimore, Maryland.

المصدر: Laboratory investigation; a journal of technical methods and pathology [Lab Invest] 2023 Aug; Vol. 103 (8), pp. 100175. Date of Electronic Publication: 2023 May 15.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Elsevier Inc Country of Publication: United States NLM ID: 0376617 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1530-0307 (Electronic) Linking ISSN: 00236837 NLM ISO Abbreviation: Lab Invest Subsets: MEDLINE

مواضيع طبية MeSH: Diagnostic Imaging* , Coloring Agents*, Immunohistochemistry ; Retrospective Studies ; Fluorescent Antibody Technique ; Cell Membrane

المؤلفون: Gordy JT; Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States., Sandhu AK; Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States., Fessler K; Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States., Luo K; Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States., Kapoor AR; Division of Infectious Diseases, Center for Tuberculosis Research, Department of Medicine, The Johns Hopkins Hospital, Baltimore, MD, United States., Ayeh SK; Division of Infectious Diseases, Center for Tuberculosis Research, Department of Medicine, The Johns Hopkins Hospital, Baltimore, MD, United States., Hui Y; Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States., Schill C; Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States., Chen F; Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States., Wang T; Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States., Karanika S; Division of Infectious Diseases, Center for Tuberculosis Research, Department of Medicine, The Johns Hopkins Hospital, Baltimore, MD, United States., Sunshine JC; The Departments of Dermatology, Pathology, and Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, United States., Karakousis PC; Division of Infectious Diseases, Center for Tuberculosis Research, Department of Medicine, The Johns Hopkins Hospital, Baltimore, MD, United States., Markham RB; Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States.

المصدر: Frontiers in immunology [Front Immunol] 2023 Jan 19; Vol. 13, pp. 1074644. Date of Electronic Publication: 2023 Jan 19 (Print Publication: 2022).

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE

مواضيع طبية MeSH: Melanoma* , Vaccines, DNA* , Cancer Vaccines*, Animals ; Mice ; Decitabine/pharmacology ; Interferon-alpha ; RNA, Messenger ; Tumor Microenvironment

المؤلفون: Czech MM; National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA., Dioverti MV; Division of Infectious Diseases, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Karaba AH; Division of Infectious Diseases, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Jain T; Division of Hematologic Malignancies, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Talluru SM; Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Sunshine JC; Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Kang J; Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Parrish N; Division of Medical Microbiology, Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Kates OS; Division of Infectious Diseases, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

المصدر: Open forum infectious diseases [Open Forum Infect Dis] 2022 Nov 29; Vol. 9 (12), pp. ofac643. Date of Electronic Publication: 2022 Nov 29 (Print Publication: 2022).

نوع المنشور: Case Reports

بيانات الدورية: Publisher: Published by Oxford University Press on behalf of the Infectious Diseases Society of America Country of Publication: United States NLM ID: 101637045 Publication Model: eCollection Cited Medium: Print ISSN: 2328-8957 (Print) Linking ISSN: 23288957 NLM ISO Abbreviation: Open Forum Infect Dis Subsets: PubMed not MEDLINE

المؤلفون: Almodovar Cruz GE; Department of Dermatology at Johns Hopkins University School of Medicine, Sidney Kimmel Comprehensive Cancer Center and Bloomberg-Kimmel Institute for Cancer Immunotherapy at Johns Hopkins, Baltimore, Maryland, USA., Kaunitz G; Department of Dermatology at Johns Hopkins University School of Medicine, Sidney Kimmel Comprehensive Cancer Center and Bloomberg-Kimmel Institute for Cancer Immunotherapy at Johns Hopkins, Baltimore, Maryland, USA., Stein JE; Department of Pathology at Johns Hopkins University School of Medicine, Sidney Kimmel Comprehensive Cancer Center and Bloomberg-Kimmel Institute for Cancer Immunotherapy at Johns Hopkins, Baltimore, Maryland, USA., Sander I; Department of Dermatology at Johns Hopkins University School of Medicine, Sidney Kimmel Comprehensive Cancer Center and Bloomberg-Kimmel Institute for Cancer Immunotherapy at Johns Hopkins, Baltimore, Maryland, USA., Hollmann T; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York, USA., Cottrell TR; Department of Pathology at Johns Hopkins University School of Medicine, Sidney Kimmel Comprehensive Cancer Center and Bloomberg-Kimmel Institute for Cancer Immunotherapy at Johns Hopkins, Baltimore, Maryland, USA., Taube JM; Department of Dermatology at Johns Hopkins University School of Medicine, Sidney Kimmel Comprehensive Cancer Center and Bloomberg-Kimmel Institute for Cancer Immunotherapy at Johns Hopkins, Baltimore, Maryland, USA.; Department of Pathology at Johns Hopkins University School of Medicine, Sidney Kimmel Comprehensive Cancer Center and Bloomberg-Kimmel Institute for Cancer Immunotherapy at Johns Hopkins, Baltimore, Maryland, USA.; Department of Oncology at Johns Hopkins University School of Medicine, Sidney Kimmel Comprehensive Cancer Center and Bloomberg-Kimmel Institute for Cancer Immunotherapy at Johns Hopkins, Baltimore, Maryland, USA., Sunshine JC; Department of Dermatology at Johns Hopkins University School of Medicine, Sidney Kimmel Comprehensive Cancer Center and Bloomberg-Kimmel Institute for Cancer Immunotherapy at Johns Hopkins, Baltimore, Maryland, USA.; Department of Pathology at Johns Hopkins University School of Medicine, Sidney Kimmel Comprehensive Cancer Center and Bloomberg-Kimmel Institute for Cancer Immunotherapy at Johns Hopkins, Baltimore, Maryland, USA.

المصدر: Journal of cutaneous pathology [J Cutan Pathol] 2022 Aug; Vol. 49 (8), pp. 701-708. Date of Electronic Publication: 2022 May 16.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley Country of Publication: United States NLM ID: 0425124 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1600-0560 (Electronic) Linking ISSN: 03036987 NLM ISO Abbreviation: J Cutan Pathol Subsets: MEDLINE

مواضيع طبية MeSH: Graft vs Host Disease* , Lichen Planus*/pathology, Humans ; Immunohistochemistry ; Skin/pathology ; T-Lymphocytes/pathology

المؤلفون: Labadie JG; Department of Dermatology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois., Compres E; Department of Dermatology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois., Sunshine JC; Department of Dermatology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.; Department of Dermatopathology, Northwestern University, Chicago, Illinois., Alam M; Department of Dermatology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois., Gerami P; Department of Dermatology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.; Department of Dermatopathology, Northwestern University, Chicago, Illinois., Harikumar V; Department of Dermatology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois., Poon E; Department of Dermatology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois., Arndt KA; SkinCare Physicians, Chestnut Hill, Massachusetts.; Warren Alpert Medical School of Brown University, Providence, Rhode Island., Dover JS; SkinCare Physicians, Chestnut Hill, Massachusetts.; Yale University School of Medicine, New Haven, Connecticut.; Warren Alpert Medical School of Brown University, Providence, Rhode Island.

المصدر: Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] [Dermatol Surg] 2022 Jan 01; Vol. 48 (1), pp. 57-60.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wolters Kluwer Health Country of Publication: United States NLM ID: 9504371 Publication Model: Print Cited Medium: Internet ISSN: 1524-4725 (Electronic) Linking ISSN: 10760512 NLM ISO Abbreviation: Dermatol Surg Subsets: MEDLINE

مواضيع طبية MeSH: Color*, Erythema/*diagnosis , Keratosis, Actinic/*diagnosis , Skin/*diagnostic imaging, Dermoscopy ; Erythema/immunology ; Erythema/pathology ; Humans ; Keratosis, Actinic/immunology ; Keratosis, Actinic/pathology ; Photography ; Retrospective Studies ; Skin/immunology ; Skin/pathology ; Triage

المؤلفون: Kim J; Department of Biomedical Engineering and the Translational Tissue Engineering Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Institute for Nanobiotechnology, Johns Hopkins University, Baltimore, MD, USA., Vaughan HJ; Department of Biomedical Engineering and the Translational Tissue Engineering Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Institute for Nanobiotechnology, Johns Hopkins University, Baltimore, MD, USA., Zamboni CG; Department of Biomedical Engineering and the Translational Tissue Engineering Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Institute for Nanobiotechnology, Johns Hopkins University, Baltimore, MD, USA., Sunshine JC; Department of Biomedical Engineering and the Translational Tissue Engineering Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Institute for Nanobiotechnology, Johns Hopkins University, Baltimore, MD, USA; Department of Pathology, Johns Hopkins University, Baltimore, MD, USA., Green JJ; Department of Biomedical Engineering and the Translational Tissue Engineering Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Institute for Nanobiotechnology, Johns Hopkins University, Baltimore, MD, USA; Department of Materials Science and Engineering, Johns Hopkins University, Baltimore, MD, USA; Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD, USA; Departments of Neurosurgery, Oncology, and Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD, USA. Electronic address: green@jhu.edu.

المصدر: Journal of controlled release : official journal of the Controlled Release Society [J Control Release] 2021 Sep 10; Vol. 337, pp. 105-116. Date of Electronic Publication: 2021 Jul 20.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Science Publishers Country of Publication: Netherlands NLM ID: 8607908 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4995 (Electronic) Linking ISSN: 01683659 NLM ISO Abbreviation: J Control Release Subsets: MEDLINE

مواضيع طبية MeSH: Nanoparticles*, Animals ; DNA/genetics ; Gene Expression ; Mice ; Plasmids/genetics ; Tissue Distribution ; Transfection

المؤلفون: Berry S; The Mark Foundation Center for Advanced Genomics and Imaging, Johns Hopkins University, Baltimore, MD 21287, USA.; Bloomberg~Kimmel Institute for Cancer Immunotherapy and Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD 21287, USA.; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Giraldo NA; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Green BF; The Mark Foundation Center for Advanced Genomics and Imaging, Johns Hopkins University, Baltimore, MD 21287, USA.; Bloomberg~Kimmel Institute for Cancer Immunotherapy and Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD 21287, USA.; Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Cottrell TR; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Stein JE; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Engle EL; The Mark Foundation Center for Advanced Genomics and Imaging, Johns Hopkins University, Baltimore, MD 21287, USA.; Bloomberg~Kimmel Institute for Cancer Immunotherapy and Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD 21287, USA.; Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Xu H; The Mark Foundation Center for Advanced Genomics and Imaging, Johns Hopkins University, Baltimore, MD 21287, USA.; Bloomberg~Kimmel Institute for Cancer Immunotherapy and Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD 21287, USA.; Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Ogurtsova A; The Mark Foundation Center for Advanced Genomics and Imaging, Johns Hopkins University, Baltimore, MD 21287, USA.; Bloomberg~Kimmel Institute for Cancer Immunotherapy and Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD 21287, USA.; Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Roberts C; Bloomberg~Kimmel Institute for Cancer Immunotherapy and Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD 21287, USA.; Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Wang D; Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Nguyen P; Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Zhu Q; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Soto-Diaz S; Bloomberg~Kimmel Institute for Cancer Immunotherapy and Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD 21287, USA.; Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Loyola J; Bloomberg~Kimmel Institute for Cancer Immunotherapy and Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD 21287, USA.; Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Sander IB; Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Wong PF; Department of Pathology, Yale University School of Medicine, New Haven, CT 06510, USA., Jessel S; Department of Pathology, Yale University School of Medicine, New Haven, CT 06510, USA., Doyle J; Department of Astronomy and Physics, Johns Hopkins University, Baltimore, MD 21218, USA.; Institute for Data Intensive Engineering and Science, Johns Hopkins University, Baltimore, MD 21218, USA., Signer D; Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Wilton R; Department of Astronomy and Physics, Johns Hopkins University, Baltimore, MD 21218, USA.; Institute for Data Intensive Engineering and Science, Johns Hopkins University, Baltimore, MD 21218, USA., Roskes JS; Department of Astronomy and Physics, Johns Hopkins University, Baltimore, MD 21218, USA.; Institute for Data Intensive Engineering and Science, Johns Hopkins University, Baltimore, MD 21218, USA., Eminizer M; Department of Astronomy and Physics, Johns Hopkins University, Baltimore, MD 21218, USA.; Institute for Data Intensive Engineering and Science, Johns Hopkins University, Baltimore, MD 21218, USA., Park S; The Mark Foundation Center for Advanced Genomics and Imaging, Johns Hopkins University, Baltimore, MD 21287, USA.; Department of Radiology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Sunshine JC; Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Jaffee EM; The Mark Foundation Center for Advanced Genomics and Imaging, Johns Hopkins University, Baltimore, MD 21287, USA.; Bloomberg~Kimmel Institute for Cancer Immunotherapy and Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD 21287, USA.; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Baras A; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., De Marzo AM; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Topalian SL; Bloomberg~Kimmel Institute for Cancer Immunotherapy and Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD 21287, USA.; Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Kluger H; Division of Medical Oncology, Department of Medicine, Yale University School of Medicine, New Haven, CT 06510, USA., Cope L; The Mark Foundation Center for Advanced Genomics and Imaging, Johns Hopkins University, Baltimore, MD 21287, USA.; Bloomberg~Kimmel Institute for Cancer Immunotherapy and Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD 21287, USA.; Division of Biostatistics and Bioinformatics, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Lipson EJ; The Mark Foundation Center for Advanced Genomics and Imaging, Johns Hopkins University, Baltimore, MD 21287, USA.; Bloomberg~Kimmel Institute for Cancer Immunotherapy and Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD 21287, USA.; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Danilova L; The Mark Foundation Center for Advanced Genomics and Imaging, Johns Hopkins University, Baltimore, MD 21287, USA.; Bloomberg~Kimmel Institute for Cancer Immunotherapy and Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD 21287, USA.; Division of Biostatistics and Bioinformatics, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Anders RA; The Mark Foundation Center for Advanced Genomics and Imaging, Johns Hopkins University, Baltimore, MD 21287, USA.; Bloomberg~Kimmel Institute for Cancer Immunotherapy and Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD 21287, USA.; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Rimm DL; Department of Pathology, Yale University School of Medicine, New Haven, CT 06510, USA., Pardoll DM; The Mark Foundation Center for Advanced Genomics and Imaging, Johns Hopkins University, Baltimore, MD 21287, USA.; Bloomberg~Kimmel Institute for Cancer Immunotherapy and Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD 21287, USA.; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Szalay AS; The Mark Foundation Center for Advanced Genomics and Imaging, Johns Hopkins University, Baltimore, MD 21287, USA.; Department of Astronomy and Physics, Johns Hopkins University, Baltimore, MD 21218, USA.; Institute for Data Intensive Engineering and Science, Johns Hopkins University, Baltimore, MD 21218, USA., Taube JM; The Mark Foundation Center for Advanced Genomics and Imaging, Johns Hopkins University, Baltimore, MD 21287, USA. jtaube1@jhmi.edu.; Bloomberg~Kimmel Institute for Cancer Immunotherapy and Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD 21287, USA.; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.; Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.

المصدر: Science (New York, N.Y.) [Science] 2021 Jun 11; Vol. 372 (6547).

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE

مواضيع طبية MeSH: Fluorescent Antibody Technique*, Antineoplastic Agents, Immunological/*therapeutic use , Biomarkers, Tumor/*analysis , Melanoma/*drug therapy , Programmed Cell Death 1 Receptor/*antagonists & inhibitors, Adult ; Aged ; Aged, 80 and over ; Antigens, CD/analysis ; Antigens, Differentiation, Myelomonocytic/analysis ; B7-H1 Antigen/analysis ; CD8 Antigens/analysis ; Female ; Forkhead Transcription Factors/analysis ; Humans ; Immune Checkpoint Proteins/analysis ; Macrophages/chemistry ; Male ; Melanoma/chemistry ; Melanoma/immunology ; Melanoma/pathology ; Middle Aged ; Prognosis ; Programmed Cell Death 1 Receptor/analysis ; Progression-Free Survival ; Receptors, Cell Surface/analysis ; SOXE Transcription Factors/analysis ; Single-Cell Analysis ; T-Lymphocyte Subsets/chemistry ; T-Lymphocyte Subsets/immunology ; Treatment Outcome ; Tumor Microenvironment