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1دورية أكاديمية
المؤلفون: Susan E Knudson, Divya Awasthi, Kunal Kumar, Alexandra Carreau, Laurent Goullieux, Sophie Lagrange, Hélèn Vermet, Iwao Ojima, Richard A Slayden
المصدر: PLoS ONE, Vol 9, Iss 4, p e93953 (2014)
وصف الملف: electronic resource
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المؤلفون: Richard A. Slayden, Susan E. Knudson, Riccardo Russo, Eric Singleton, Simon Tong, Krupanandan Haranahalli, Nancy D. Connell, Saerom Kim, Lei Chen, Monaf Awwa, Iwao Ojima
المصدر: RSC Med Chem
مصطلحات موضوعية: Pharmacology, 0303 health sciences, biology, Chemistry, Stereochemistry, Organic Chemistry, Pharmaceutical Science, Growth inhibitory, Biochemistry, Bacterial cell structure, 03 medical and health sciences, 0302 clinical medicine, 030228 respiratory system, Mic values, Drug Discovery, biology.protein, Molecular Medicine, Structure–activity relationship, Temperature sensitive, FtsZ, 030304 developmental biology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ab01f8671614e35a5bd002bacc95641
https://europepmc.org/articles/PMC8132993/ -
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المؤلفون: Sandra Eltschkner, Weixuan Yu, Jonathan Merino, Caroline Kisker, James J. Truglio, Eleanor K. H. Allen, Ben Moree, Neil Thivalapill, Shabnam Davoodi, Lauren A. Spagnuolo, Peter J. Tonge, Joshua Salafsky, Richard A. Slayden, Fereidoon Daryaee, Annica Pschibul, Susan E. Knudson
المصدر: Journal of the American Chemical Society. 139:3417-3429
مصطلحات موضوعية: Models, Molecular, 0301 basic medicine, Time Factors, Stereochemistry, Kinetics, Triazole, Crystallography, X-Ray, Biochemistry, Article, Catalysis, Reaction coordinate, 03 medical and health sciences, chemistry.chemical_compound, Colloid and Surface Chemistry, Humans, Inhibins, Enzyme kinetics, Molecular Structure, Chemistry, INHA, Diphenyl ether, General Chemistry, Triazoles, Combinatorial chemistry, Transition state, 030104 developmental biology, Thermodynamics, Lead compound
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المؤلفون: Kunal Kumar, Iwao Ojima, Hélène Vermet, Susan E. Knudson, Alexandra Carreau, Sophie Lagrange, Laurent Goullieux, Richard A. Slayden, Divya Awasthi
المصدر: Journal of Antimicrobial Chemotherapy. 70:3070-3073
مصطلحات موضوعية: Microbiology (medical), Tuberculosis, Cell Survival, Antitubercular Agents, Administration, Oral, Spleen, Microbial Sensitivity Tests, Microbiology, Mycobacterium tuberculosis, Mice, Bacterial Proteins, Drug Stability, In vivo, Chlorocebus aethiops, Isoniazid, medicine, Animals, Potency, Pharmacology (medical), Vero Cells, Original Research, Pharmacology, biology, business.industry, medicine.disease, biology.organism_classification, Cytoskeletal Proteins, Disease Models, Animal, Treatment Outcome, Infectious Diseases, medicine.anatomical_structure, Inactivation, Metabolic, Toxicity, Vero cell, Benzimidazoles, business, Cell Division, Injections, Intraperitoneal, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d977a30cd4f47639ae1fc8514266d39
https://doi.org/10.1093/jac/dkv226 -
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المؤلفون: Susan E. Knudson, Christopher M. Goins, Richard A. Slayden, Sandeep Thanna, Steven J. Sucheck, Donald R. Ronning
مصطلحات موضوعية: Stereochemistry, Antitubercular Agents, chemistry.chemical_element, Microbial Sensitivity Tests, 010402 general chemistry, 01 natural sciences, Article, Mycobacterium tuberculosis, chemistry.chemical_compound, Selenium Compounds, Alkyl, Potassium selenocyanate, chemistry.chemical_classification, biology, 010405 organic chemistry, Ebselen, Ligand, Organic Chemistry, biology.organism_classification, Photochemical Processes, Copper, Cycloaddition, Carbon, 0104 chemical sciences, chemistry, Derivative (chemistry)
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d50254c4cdc8ba69c4f85f321cc6930c
https://europepmc.org/articles/PMC6143291/ -
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المؤلفون: Maria Hirschbeck, Christoph A. Sotriffer, Gopal R. Bommineni, Peter J. Tonge, S. Shah, Jason E. Cummings, Sandra Eltschkner, Andrew Chang, Susan E. Knudson, Weixuan Yu, Pan Pan, Yang Lu, Mona Tareilus, Richard A. Slayden, Johannes Schiebel, Li Liu, Caroline Kisker, Stephen G. Walker
المصدر: Journal of Biological Chemistry. 289:15987-16005
مصطلحات موضوعية: Staphylococcus aureus, Pyridones, Stereochemistry, Microbial Sensitivity Tests, Reductase, Crystallography, X-Ray, medicine.disease_cause, Polymerase Chain Reaction, Biochemistry, Mice, medicine, Animals, Enzyme Inhibitors, Molecular Biology, DNA Primers, Mice, Inbred ICR, Base Sequence, Molecular Structure, biology, Drug discovery, Rational design, Cell Biology, Enoyl-(Acyl-Carrier-Protein) Reductase (NADH), Enzyme structure, Anti-Bacterial Agents, Acyl carrier protein, Enzyme inhibitor, Drug Design, Enzymology, biology.protein, Female, Antibacterial activity
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71c8bfde90ae1c1d56a2e538f8c95c81
https://doi.org/10.1074/jbc.m113.532804 -
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المؤلفون: Sunayana Kapil, Susan E. Knudson, Anna E. Grzegorzewicz, Steven J. Sucheck, Mary Jackson, Richard A. Slayden, Christopher M. Goins, Donald R. Ronning, Sandeep Thanna
المصدر: Organicbiomolecular chemistry. 14(25)
مصطلحات موضوعية: 0301 basic medicine, Tuberculosis, Antitubercular Agents, Drug resistance, Chemistry Techniques, Synthetic, Microbial Sensitivity Tests, Thiophenes, Biochemistry, Article, Microbiology, Mycolic acid, Mycobacterium tuberculosis, 03 medical and health sciences, medicine, Potency, Physical and Theoretical Chemistry, chemistry.chemical_classification, biology, Chemistry, Organic Chemistry, Isoniazid, biology.organism_classification, medicine.disease, 030104 developmental biology, Enzyme, Mycolic Acids, Rifampicin, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74c31a495d8f080dcb731e5e09fc211a
https://pubmed.ncbi.nlm.nih.gov/27251120 -
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المؤلفون: Richard A. Slayden, Kanishk Kapilashrami, Gopal R. Bommineni, Stephen G. Walker, Susan E. Knudson, Chendi Gu, Jason E. Cummings, Yang Lu, Peter J. Tonge
مصطلحات موضوعية: 0301 basic medicine, Male, Methicillin-Resistant Staphylococcus aureus, Staphylococcus aureus, Burkholderia pseudomallei, Klebsiella pneumoniae, Yersinia pestis, 030106 microbiology, Molecular Conformation, Microbial Sensitivity Tests, Thiophenes, medicine.disease_cause, Article, Microbiology, Cell Line, 03 medical and health sciences, chemistry.chemical_compound, Mice, Structure-Activity Relationship, In vivo, Drug Discovery, 3-Oxoacyl-(Acyl-Carrier-Protein) Synthase, medicine, Animals, Humans, Enzyme Inhibitors, Francisella tularensis, chemistry.chemical_classification, Natural product, biology, Dose-Response Relationship, Drug, Nocardia, Staphylococcal Infections, biology.organism_classification, bacterial infections and mycoses, Anti-Bacterial Agents, Klebsiella Infections, Disease Models, Animal, Enzyme, chemistry, Biochemistry, Molecular Medicine
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a3d0587513a5d0dcf847ce603582ba6
https://europepmc.org/articles/PMC4917603/ -
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المؤلفون: Peter J. Tonge, Pan Pan, Richard A. Slayden, Gopal R. Bommineni, Jason E. Cummings, Susan E. Knudson
المصدر: Tuberculosis (Edinburgh, Scotland). 101
مصطلحات موضوعية: 0301 basic medicine, Microbiology (medical), Drug, Combination therapy, media_common.quotation_subject, Drug Compounding, 030106 microbiology, Immunology, Antitubercular Agents, Microbial Sensitivity Tests, Pharmacology, Microbiology, Article, Mycobacterium tuberculosis, 03 medical and health sciences, chemistry.chemical_compound, Drug Delivery Systems, Pharmacokinetics, Bacterial Proteins, Drug Discovery, Potency, Animals, Tuberculosis, media_common, biology, INHA, Phenyl Ethers, Diphenyl ether, Drug Synergism, biology.organism_classification, Mice, Inbred C57BL, Disease Models, Animal, 030104 developmental biology, Infectious Diseases, chemistry, Solubility, Emulsifying Agents, Drug delivery, Drug Therapy, Combination, Oxidoreductases, Spleen
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المؤلفون: Susan E. Knudson, Richard A. Slayden, Nina Liu, Xiaokai Li, Peter J. Tonge, Huaning Zhang
المصدر: Bioorganic & Medicinal Chemistry Letters. 20:6306-6309
مصطلحات موضوعية: Magnetic Resonance Spectroscopy, Tuberculosis, Clinical Biochemistry, Antitubercular Agents, Pharmaceutical Science, Microbial Sensitivity Tests, Biochemistry, Article, Mycobacterium tuberculosis, Structure-Activity Relationship, Drug Discovery, medicine, Structure–activity relationship, Molecular Biology, Antibacterial agent, chemistry.chemical_classification, biology, Chemistry, Organic Chemistry, Oxo-Acid-Lyases, biology.organism_classification, medicine.disease, In vitro, Benzoxazines, Enzyme, Molecular Medicine, Antibacterial activity, Bacteria