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1دورية أكاديمية
المؤلفون: Alexandro Membrino, Susanna Cogoi, Erik B Pedersen, Luigi E Xodo
المصدر: PLoS ONE, Vol 6, Iss 9, p e24421 (2011)
وصف الملف: electronic resource
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المؤلفون: Luigi E. Xodo, Susanna Cogoi, Sabina Cauci, Valentina Rapozzi
المصدر: Biochimica et Biophysica Acta (BBA) - General Subjects. 1861:1389-1398
مصطلحات موضوعية: 0301 basic medicine, Transcription, Genetic, endocrine system diseases, Heterogeneous Nuclear Ribonucleoprotein A1, Ligands, medicine.disease_cause, Biochemistry, chemistry.chemical_compound, 0302 clinical medicine, Transcription (biology), Heterogeneous-Nuclear Ribonucleoprotein Group A-B, Transcriptional regulation, Nuclear protein, Promoter Regions, Genetic, hnRNP A1, Genetics, Guanosine, G-quadruplex, DNA, Neoplasm, Transcription regulation, Gene Expression Regulation, Neoplastic, 030220 oncology & carcinogenesis, KRAS, Protein Binding, Transcriptional Activation, Biophysics, Biology, Proto-Oncogene Proteins p21(ras), Structure-Activity Relationship, 03 medical and health sciences, Pancreatic cancer, medicine, Humans, KRAS oncogene, Molecular Biology, Gene, Binding Sites, Polymorphism, Genetic, G4 unfolding, medicine.disease, digestive system diseases, G-Quadruplexes, Pancreatic Neoplasms, 030104 developmental biology, chemistry, Cancer research, DNA
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المؤلفون: Luigi E. Xodo, Valentina Rapozzi, Susanna Cogoi
المصدر: Future Medicinal Chemistry. 8:179-194
مصطلحات موضوعية: B78-H1, cancer, cationic phthalocyanines, cationic porphyrins, KRAS, mRNA suppression, Panc-1, photodynamic therapy, RNA-quadruplexes, singlet oxygen, Animals, Antineoplastic Agents, DNA, G-Quadruplexes, Humans, Indoles, Neoplasms, Photochemotherapy, Photosensitizing Agents, Porphyrins, RNA, Messenger, ras Proteins, Drug Discovery3003 Pharmaceutical Science, Pharmacology, Molecular Medicine, Medicine (all), 0301 basic medicine, medicine.medical_treatment, Messenger, Photodynamic therapy, Isoindoles, medicine.disease_cause, chemistry.chemical_compound, Drug Discovery, heterocyclic compounds, Chemistry, Singlet oxygen, Biochemistry, 03 medical and health sciences, medicine, Cationic polymerization, RNA, Cancer, medicine.disease, 030104 developmental biology, Nucleic acid
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المساهمون: Cogoi, Susanna, Ferino, Annalisa, Miglietta, Giulia, Pedersen, Erik B, Xodo, Luigi E
المصدر: Cogoi, S, Ferino, A, Miglietta, G, Pedersen, E B & Xodo, L E 2018, ' The regulatory G4 motif of the Kirsten ras (KRAS) gene is sensitive to guanine oxidation : implications on transcription ', Nucleic Acids Research, vol. 46, no. 2, pp. 661–676 . https://doi.org/10.1093/nar/gkx1142
Nucleic Acids Researchمصطلحات موضوعية: G-QUADRUPLEX STRUCTURES, 0301 basic medicine, Guanine, Transcription, Genetic, Heterogeneous Nuclear Ribonucleoprotein A1, I-MOTIF, Biology, medicine.disease_cause, G-quadruplex, ONCOGENIC KRAS, DNA Glycosylases, SACCHAROMYCES-CEREVISIAE, Proto-Oncogene Proteins p21(ras), 03 medical and health sciences, 0302 clinical medicine, Transcription (biology), Cell Line, Tumor, Gene expression, medicine, Genetics, Journal Article, Humans, heterocyclic compounds, Epigenetics, Promoter Regions, Genetic, Gene, PANCREATIC-CANCER CELLS, Oncogene, TUMOR-GROWTH, Gene regulation, Chromatin and Epigenetics, DNA, PROMOTER IMPLICATIONS, Molecular biology, DNA-Binding Proteins, G-Quadruplexes, HEK293 Cells, 030104 developmental biology, DNA-DAMAGE, BASE-EXCISION-REPAIR, 030220 oncology & carcinogenesis, SIGNALING PATHWAY, KRAS, Transcription Initiation Site, Oxidation-Reduction, Chromatin immunoprecipitation, Protein Binding, Transcription Factors
وصف الملف: application/pdf; ELETTRONICO
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1728712b73db4469e06466209051d4b7
https://findresearcher.sdu.dk:8443/ws/files/135420000/The_regulatory_G4_motif_of_the_Kirsten_ras_KRAS_gene_is_sensitive_to_guanine_oxidation.pdf -
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المؤلفون: Susanna Cogoi, Andrey E. Shchekotikhin, Alexander S. Tikhomirov, Jessica Marinello, Giulia Miglietta, Giovanni Capranico, Luigi E. Xodo
المساهمون: Miglietta, Giulia, Cogoi, Susanna, Marinello, Jessica, Capranico, Giovanni, Tikhomirov, Alexander S., Shchekotikhin, Andrey, Xodo, Luigi E.
المصدر: Journal of medicinal chemistry. 60(23)
مصطلحات موضوعية: 0301 basic medicine, Antineoplastic Agents, Thiophenes, medicine.disease_cause, Antineoplastic Agent, Proto-Oncogene Proteins p21(ras), Small Molecule Libraries, 03 medical and health sciences, 0302 clinical medicine, 5' Untranslated Region, Small Molecule Librarie, Thiophene, Cell Line, Tumor, Drug Discovery, medicine, Protein biosynthesis, G-Quadruplexe, Humans, Messenger RNA, Oncogene, Protein Biosynthesi, Cell growth, Chemistry, Drug Discovery3003 Pharmaceutical Science, Pancreatic Neoplasm, RNA, Molecular biology, G-Quadruplexes, Pancreatic Neoplasms, 030104 developmental biology, Molecular Medicine, 030220 oncology & carcinogenesis, Protein Biosynthesis, Cancer cell, KRAS, 5' Untranslated Regions, Human
وصف الملف: STAMPA
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6Potent Apoptotic Response Induced by Chloroacetamidine Anthrathiophenediones in Bladder Cancer Cells
المؤلفون: Susanna Cogoi, Sonia Zorzet, Andrey E. Shchekotikhin, Luigi E. Xodo
المساهمون: Cogoi, S., Zorzet, Sonia, Shchekotikhin, A. E., Xodo, L. E.
المصدر: Journal of Medicinal Chemistry. 58:5476-5485
مصطلحات موضوعية: experimental model, Antineoplastic Agents, Apoptosis, Chloroacetamidine-Anthrathiophenedione, Thiophenes, urologic and male genital diseases, Acetamides, Alleles, Animals, Biological Transport, Cell Line, Tumor, Cell Proliferation, Cyclin D1, Drug Design, G-Quadruplexes, G2 Phase Cell Cycle Checkpoints, Genes, ras, Humans, Mice, Substrate Specificity, Survival Analysis, Urinary Bladder Neoplasms, Xenograft Model Antitumor Assays, Molecular Medicine, Drug Discovery3003 Pharmaceutical Science, Medicine (all), Cell Line, chemistry.chemical_compound, Annexin, Chloroacetamidine-Anthrathiophenediones, Bladder cancer, Drug Discovery, Propidium iodide, HRAS, ras, Caspase, Tumor, biology, Cell cycle, Genes, chemistry, Biochemistry, Cell culture, Cancer cell, biology.protein, Cancer research
وصف الملف: ELETTRONICO
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المؤلفون: Andrey E. Shchekotikhin, Luigi E. Xodo, Susanna Cogoi
المصدر: Nucleic Acids Research
مصطلحات موضوعية: Transcriptional Activation, Biology, G-quadruplex, DNA-binding protein, Proto-Oncogene Proteins p21(ras), chemistry.chemical_compound, Transcription (biology), Cell Line, Tumor, Genetics, Humans, heterocyclic compounds, HRAS, Gene Silencing, Promoter Regions, Genetic, Transcription factor, Zinc finger, Zinc finger transcription factor, Gene regulation, Chromatin and Epigenetics, DNA, Molecular biology, DNA-Binding Proteins, G-Quadruplexes, Gene Expression Regulation, Neoplastic, chemistry, Urinary Bladder Neoplasms, Transcription Factors
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a136aa14386f96ac901d701607170231
http://europepmc.org/articles/PMC4117790 -
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المؤلفون: Susanna Cogoi, Luigi E. Xodo
مصطلحات موضوعية: 0301 basic medicine, Neuroblastoma RAS viral oncogene homolog, Transcription, Genetic, Antigene strategies, Biophysics, NRAS, Biology, Biochemistry, 5'-UTR, G-quadruplex, HRAS, KRAS, Promoter, 5' Untranslated Regions, Genome, Human, Humans, Neoplasms, Promoter Regions, Genetic, Proto-Oncogene Proteins p21(ras), Small Molecule Libraries, G-Quadruplexes, Genetics, Molecular Biology, Structural Biology, Medicine (all), Promoter Regions, 03 medical and health sciences, chemistry.chemical_compound, Genetic, Transcription (biology), heterocyclic compounds, Gene, Genome, 030104 developmental biology, chemistry, Human genome, Transcription, DNA, Human
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95294590cfcab7f9a15bccae1b0c3c28
http://hdl.handle.net/11390/1109322 -
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المؤلفون: Ulla Jakobsen, Susanna Cogoi, Erik B. Pedersen, Luigi E. Xodo, Stefan Vogel
المصدر: Cogoi, S, Jakobsen, U, Pedersen, E B, Vogel, S & Xodo, L E 2016, ' Lipid-modified G4-decoy oligonucleotide anchored to nanoparticles : delivery and bioactivity in pancreatic cancer cells ', Scientific Reports, vol. 6, 38468, pp. 1-13 . https://doi.org/10.1038/srep38468
Scientific Reportsمصطلحات موضوعية: 0301 basic medicine, Cell, Oligonucleotides, Cell-Penetrating Peptides, Adenocarcinoma, 010402 general chemistry, medicine.disease_cause, 01 natural sciences, Article, Proto-Oncogene Proteins p21(ras), 03 medical and health sciences, chemistry.chemical_compound, Cell Line, Tumor, Pancreatic cancer, medicine, KRAS, Humans, G4-decoys, Promoter Regions, Genetic, Clonogenic assay, Transcription factor, POPC, POPC liposomes, Multidisciplinary, Oligonucleotide, medicine.disease, Lipids, Molecular biology, digestive system diseases, 0104 chemical sciences, Pancreatic Neoplasms, 030104 developmental biology, medicine.anatomical_structure, chemistry, Cell culture, Liposomes, Phosphatidylcholines, Nanoparticles, POPC liposomes, KRAS, G4-decoys
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31a79245371aca90d114fc3d48c72d01
http://hdl.handle.net/11390/1109324 -
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المؤلفون: Alexandro Membrino, Luigi E. Xodo, Manikandan Paramasivam, Kazunari K. Yokoyama, Susanna Cogoi
المصدر: Journal of Biological Chemistry. 285:22003-22016
مصطلحات موضوعية: Chromatin Immunoprecipitation, Guanine, Indoles, Transcription, Genetic, Molecular Sequence Data, Electrophoretic Mobility Shift Assay, Isoindoles, Biology, Ligands, Biochemistry, DNA-binding protein, Proto-Oncogene Proteins p21(ras), Mice, Transcription (biology), Fluorescence Resonance Energy Transfer, Animals, Gene Regulation, Protein–DNA interaction, Promoter Regions, Genetic, Molecular Biology, Transcription factor, Zinc finger, Base Sequence, General transcription factor, Protein Stability, Promoter, Cell Biology, Molecular biology, DNA-Binding Proteins, G-Quadruplexes, NIH 3T3 Cells, Nucleic Acid Conformation, Mutant Proteins, Poly(ADP-ribose) Polymerases, Chromatin immunoprecipitation, Protein Binding, Transcription Factors
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fc3a2b3b7ce37895008e2615d1522d8
https://doi.org/10.1074/jbc.m110.101923
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