المؤلفون: Sandra Wimberger, Nina Akrap, Mike Firth, Johan Brengdahl, Susanna Engberg, Marie K. Schwinn, Michael R. Slater, Anders Lundin, Pei-Pei Hsieh, Songyuan Li, Silvia Cerboni, Jonathan Sumner, Burcu Bestas, Bastian Schiffthaler, Björn Magnusson, Silvio Di Castro, Preeti Iyer, Mohammad Bohlooly-Y, Thomas Machleidt, Steve Rees, Ola Engkvist, Tyrell Norris, Elaine B. Cadogan, Josep V. Forment, Saša Šviković, Pinar Akcakaya, Amir Taheri-Ghahfarokhi, Marcello Maresca

المصدر: Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/4bb0c69502654c769c92ef8642d93a46

المؤلفون: Sandra Wimberger, Nina Akrap, Mike Firth, Johan Brengdahl, Susanna Engberg, Marie K. Schwinn, Michael R. Slater, Anders Lundin, Pei-Pei Hsieh, Songyuan Li, Silvia Cerboni, Jonathan Sumner, Burcu Bestas, Bastian Schiffthaler, Björn Magnusson, Silvio Di Castro, Preeti Iyer, Bohlooly-Y Mohammad, Thomas Machleidt, Steve Rees, Ola Engkvist, Tyrell Norris, Elaine Cadogan, Josep V. Forment, Saša Šviković, Pinar Akcakaya, Amir Taheri-Ghahfarokhi, Marcello Maresca

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::a08601f80723c09f5557274e0ab558c2
https://doi.org/10.1101/2022.12.15.520396

المؤلفون: Raghuraman C. Srinivasan, Carl Jorns, Anna Forslöw, Johannes Häberle, Burcu Bestas, Tanja Scherer, Mike Firth, Towe Jakobsson, Barry Rosen, Gabriella Allegri, Olav Rooyackers, Susanna Engberg, Christina Hammarstedt, Beat Thöny, Pinar Akcakaya, Marcello Maresca, Natalie Van Zuydam, Ewa Ellis, Nicole Rimann, Mihaela Zabulica, Stephen C. Strom, Tomas Jakobsson, Roberto Gramignoli, Georgios Makris

المصدر: Mol Ther

مصطلحات موضوعية: Adult, Male, Orotic acid, Urea cycle disorder, RNA Splicing, Mutant, Biology, Mice, 03 medical and health sciences, Liver disease, 0302 clinical medicine, Ammonia, Drug Discovery, Gene expression, Genetics, medicine, Animals, Humans, Child, Molecular Biology, Cells, Cultured, Ornithine Carbamoyltransferase, Ornithine transcarbamylase deficiency, Aged, 030304 developmental biology, Gene Editing, Orotic Acid, Pharmacology, 0303 health sciences, medicine.disease, Molecular biology, Introns, Ornithine Carbamoyltransferase Deficiency Disease, Disease Models, Animal, Gene Expression Regulation, 030220 oncology & carcinogenesis, Urea cycle, Mutation, Hepatocytes, Commentary, Molecular Medicine, Female, Ex vivo, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6f7a6b2fa12b8edad953796c2d8937b
https://doi.org/10.1016/j.ymthe.2021.01.024

المؤلفون: Susanna Engberg, Amanda E. Mackenzie, Li-Chiung Lin, Graeme Milligan, Andrew B. Tobin, Tezz Quon

مصطلحات موضوعية: Pharmacology, Lipid accumulation, Chemistry, medicine.disease, Cell biology, Human hepatocyte, medicine.anatomical_structure, Cell culture, Hepatocyte, Nonalcoholic fatty liver disease, medicine, Pharmacology (medical), GPR35, G protein-coupled receptor

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e1fcdf62b9b331df14fdf6a87f0bf45
https://eprints.gla.ac.uk/258956/3/258956.pdf

المؤلفون: David Murray, Carolyn Blackett, Neil Bennett, Mark Wigglesworth, Rebecca Dixon-Steele, Sinead Knight, Anet Varghese, Susanna Engberg, Helen Plant, Paula McArdle, Paul Harper, Lisa McWilliams, Anna Ramne

المصدر: SLAS Discovery. 22:732-742

مصطلحات موضوعية: 0301 basic medicine, Cell Survival, Phenotypic screening, Nanotechnology, Computational biology, Biology, 01 natural sciences, Biochemistry, Cell Line, Analytical Chemistry, 03 medical and health sciences, Drug Discovery, Animals, Humans, Throughput (business), food and beverages, High-Throughput Screening Assays, Molecular Imaging, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Phenotype, 030104 developmental biology, Microscopy, Fluorescence, Molecular Medicine, Biomarkers, Biotechnology, Cell based

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac4b0249240a57f2b7b58c7d64d2800a
https://doi.org/10.1177/2472555216683650

المؤلفون: Chris Perrey, Susanna Engberg, Bengt von Mentzer, Adrian Moody, John Edward Norris Morten, Maria Lagerström-Fermér, Ingela Ahlstedt, Tomas Drmota, Ingrid Påhlman, John Craig Smith, Erik Lindström

المصدر: Biochemical Pharmacology. 76:476-481

مصطلحات موضوعية: Agonist, medicine.medical_specialty, medicine.drug_class, Mutation, Missense, CHO Cells, Pharmacology, Biology, Transfection, Polymorphism, Single Nucleotide, Biochemistry, Saredutant, chemistry.chemical_compound, Cricetulus, Gene Frequency, Cricetinae, Internal medicine, medicine, Animals, Humans, Potency, Calcium Signaling, Receptors, Tachykinin, Chinese hamster ovary cell, Genetic Variation, Receptors, Neurokinin-2, Endocrinology, chemistry, Mutagenesis, Site-Directed, Neurokinin A, Tachykinin receptor, Endogenous agonist, Intracellular, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb412526d1bb0d81b808089af8c01b07
https://doi.org/10.1016/j.bcp.2008.06.003

المؤلفون: Anders Johansson, Tomas Drmota, Ingela Ahlstedt, Ingrid Påhlman, Erik Lindström, Bengt von Mentzer, Agnes Leffler, Svensson Arne, Elin Kristensson, Susanna Engberg

المصدر: Biochemical Pharmacology. 73:259-269

مصطلحات موضوعية: Models, Molecular, Agonist, medicine.drug_class, Molecular Sequence Data, CHO Cells, Pharmacology, Biology, Gerbil, Biochemistry, Cricetulus, Neurokinin-1 Receptor Antagonists, Cricetinae, Tachykinin receptor 1, medicine, Animals, Humans, Potency, Amino Acid Sequence, Cloning, Molecular, Receptor, Peptide sequence, DNA Primers, Base Sequence, Sequence Homology, Amino Acid, Antagonist, Receptors, Neurokinin-1, In vitro, Rats, Mutagenesis, Site-Directed, Gerbillinae

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ead55fc1350dbe27b20fa03bd9cb82ec
https://doi.org/10.1016/j.bcp.2006.09.030

المؤلفون: Jessica K. Nelson, Laura J. Sharpe, Andrew J. Brown, Emma Claire Laura Cook, Martina Moeton, Madina Karimova, Noam Zelcer, Gilles Lambert, Susanna Engberg, Anke Loregger

المساهمون: Medical Biochemistry, Amsterdam Cardiovascular Sciences, Amsterdam Gastroenterology Endocrinology Metabolism

المصدر: Molecular and cellular biology, 36(2), 285-294. American Society for Microbiology

مصطلحات موضوعية: 0301 basic medicine, Apolipoprotein E, Low-density lipoprotein receptor gene family, Lipoproteins, Ubiquitin-Protein Ligases, 030204 cardiovascular system & hematology, Cholesterol 7 alpha-hydroxylase, Cell Line, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Humans, Gene Silencing, Molecular Biology, biology, Cholesterol, Membrane Proteins, Articles, Hep G2 Cells, Cell Biology, Biosynthetic Pathways, 3. Good health, Ubiquitin ligase, Cell biology, Sterol regulatory element-binding protein, 030104 developmental biology, Receptors, LDL, Biochemistry, chemistry, HMG-CoA reductase, LDL receptor, Hepatocytes, biology.protein, lipids (amino acids, peptides, and proteins)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8889188c5edf7ba16f091a89d1f7fcf
https://pure.amc.nl/en/publications/a-march6-and-idol-e3-ubiquitin-ligase-circuit-uncouples-cholesterol-synthesis-from-lipoprotein-uptake-in-hepatocytes(ab95f43c-cbd8-4047-b203-8b61059cf4b1).html

المؤلفون: Gilles Lambert, Emma C. L. Cook, Anke Loregger, Noam Zelcer, Susanna Engberg, Laura J. Sharpe, Martina Moeton, M. Karimova, Jessica K. Nelson

المصدر: Atherosclerosis. 252:e250

مصطلحات موضوعية: 0301 basic medicine, Cholesterol synthesis, 03 medical and health sciences, 030104 developmental biology, Biochemistry, biology, Chemistry, biology.protein, Cardiology and Cardiovascular Medicine, Lipoprotein, Ubiquitin ligase

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::68087e7c4dd1d0d877dc31a48577b4a3
https://doi.org/10.1016/j.atherosclerosis.2016.07.057

المؤلفون: Susanna Engberg, Ingela Ahlstedt, Martin Billger, Lisa Öberg, Magnus K. Bjursell, Erik Lindström, Svensson Arne, Bengt von Mentzer, Agnes Leffler

المصدر: Biochemical pharmacology. 77(9)

مصطلحات موضوعية: Morpholines, Guinea Pigs, Molecular Sequence Data, CHO Cells, Pharmacology, Biology, Gerbil, Transfection, Biochemistry, Saredutant, Natural killer cell, Mice, Cricetulus, Dogs, Neurokinin-1 Receptor Antagonists, Species Specificity, Cricetinae, Talnetant, medicine, Animals, Humans, Amino Acid Sequence, Binding site, Receptor, Base Sequence, Sequence Homology, Amino Acid, Antagonist, Receptors, Neurokinin-3, Receptors, Neurokinin-2, Receptors, Neurokinin-1, Rats, medicine.anatomical_structure, Calcium, Tachykinin receptor, Gerbillinae, Sequence Alignment, Aprepitant, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::069abbe8faf0f87fdf21e9ffa6a6d426
https://pubmed.ncbi.nlm.nih.gov/19426690