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المؤلفون: Franziska Graf, Wolfgang Mück, Dominique Swerts, Kerstin J. Frank, Dorina van der Mey, Joanne Bennett, Marta Venczel, Thomas Müller, Uwe Muenster, Hans Lennernäs, Florent Mazuir, Jan Bevernage, Mei Wong, Mark McAllister, Stéphane Beilles, Loic Laplanche, Alison Margolskee, Stefania Beato, Lieve Adriaenssen, Loeckie de Zwart, Jonas Angstenberger, Xavier Pepin, Anh-Thu Nguyen-Trung, Alexander Marker, Amin Rostami-Hodjegan, P. Zane, Céline Ollier, An Van Den Bergh, Adam S. Darwich, Shriram M. Pathak, Dónal Murphy, Markus Kolhmann, Pankaj Daga, Susanne Greschat-Schade, Michael B. Bolger, Achiel Van Peer, Christer Tannergren, Priscilla Brun, Mohammed Yasin, Bertil Abrahamsson, Sara Carlert, Richard Lloyd, Christophe Tistaert, Leon Aarons, Petra Loos, Xavier Boulenc, Pascale Vicat
المصدر: Margolskee, A, Darwich, A, Pepin, X, Pathak, S M, Bolger et al, M B, Aarons, L, Rostami-Hochaghan, A, Angstenberger, J, Graf, F, Laplanche, L, Muller, T, Carlert, S, Daga, P, Murphy, D, Tannergren, C, Yasin, M, Greschat-Schade, S, Muck, W, Muenster, U, van der Mey, D, Frank, K, Lloyd, R, Adriaenssen, L, Bevernage, J, De Zwart, L, Swerts, D, Tistaert, C, Van Den Bergh, A, Van Peer, A, Beato, S, Nguyen-Trung, A-T, Bennett, J, McAllister, M, Wong, M, Zane, P, Ollier, C, Vicat, P, Kolhmann, M, Marker, A, Brun, P, Mazuir, F, Beilles, S, Venczel, M, Boulenc, X, Loos, P, Lennernas, H & Abrahamsson, B 2016, ' IMI – oral biopharmaceutics tools project – evaluation of bottom-up PBPK prediction success part 1: Characterisation of the OrBiTo database of compounds ', European Journal of Pharmaceutical Sciences . https://doi.org/10.1016/j.ejps.2016.09.027
مصطلحات موضوعية: Physiologically based pharmacokinetic modelling, Databases, Factual, Drug Evaluation, Preclinical, Administration, Oral, Pharmaceutical Science, Pharmacology, computer.software_genre, Models, Biological, 030226 pharmacology & pharmacy, Intestinal absorption, Biopharmaceutics, 03 medical and health sciences, 0302 clinical medicine, Humans, Pharmaceutical sciences, Volume of distribution, Database, Chemistry, Biopharmaceutics Classification System, Bioavailability, Biopharmaceutical, Intestinal Absorption, Pharmaceutical Preparations, 030220 oncology & carcinogenesis, computer, Forecasting
وصف الملف: application/pdf
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المؤلفون: Ingo Flamme, Iring Heisler, Michael Haerter, Peter Ellinghaus, Alexander Ehrmann, Susanne Greschat, Felix Oehme, Hartmut Beck, Martin Michels, Holger Summer, Karl Ziegelbauer, Holger Hess-Stumpp, Karl-Heinz Thierauch, Kerstin Unterschemmann
المصدر: Cancer Medicine
مصطلحات موضوعية: Cancer Research, Lung Neoplasms, Mice, Genes, Reporter, Drug Discovery, Tumor Cells, Cultured, Molecular Targeted Therapy, RNA, Small Interfering, Cancer Biology, Carbonic Anhydrases, Regulation of gene expression, Oxadiazoles, mitochondrial complex 1, Cell Hypoxia, Tumor Burden, Gene Expression Regulation, Neoplastic, Oncology, Von Hippel-Lindau Tumor Suppressor Protein, Female, Hypoxia-Inducible Factor 1, medicine.symptom, Energy source, Molecular Sequence Data, Mice, Nude, Biology, Hypoxia-Inducible Factor-Proline Dioxygenases, Small Molecule Libraries, Antigens, Neoplasm, In vivo, medicine, Animals, Humans, Radiology, Nuclear Medicine and imaging, Carbonic Anhydrase IX, Transcription factor, Cell Proliferation, Electron Transport Complex I, Dose-Response Relationship, Drug, hypoxia, Cell growth, Hypoxia (medical), Xenograft Model Antitumor Assays, Molecular biology, hypoxia-inducible factor-1, Tumor progression, Cell culture, Cancer research, Pyrazoles, Antitumor activity, Genes, Neoplasm
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المؤلفون: Andreas Ohm, Thomas Kuhlmann, Uwe Muenster, Christian Pelzetter, Thomas Backensfeld, Andreas H. Göller, Mark Jean Gnoth, Klemens Lustig, Susanne Greschat, Jörg Keldenich, Hartwig Mueller
المصدر: European Journal of Pharmaceutics and Biopharmaceutics. 78:522-530
مصطلحات موضوعية: Adult, Male, Drug, Absorption (pharmacology), Chemical Phenomena, Administration, Topical, media_common.quotation_subject, Administration, Oral, Biological Availability, Pharmaceutical Science, Permeability, Young Adult, Drug Delivery Systems, Suspensions, Pharmacokinetics, In vivo, PEG ratio, Animals, Humans, Particle Size, Rats, Wistar, Solubility, Dissolution, media_common, Mouth, Chromatography, Chemistry, General Medicine, Rats, Bioavailability, Pharmaceutical Preparations, Caco-2 Cells, Biotechnology
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المؤلفون: Claudia Rosenbaum, Gesine Kögler, Maria A. de Souza Silva, Jessica Schira, Hans Werner Müller, Patrick Küry, Susanne Greschat, Peter Wernet
المصدر: Stem Cells and Development. 17:221-232
مصطلحات موضوعية: Lineage (genetic), Dopamine, Biology, Umbilical cord, Sodium Channels, medicine, Animals, Humans, Cells, Cultured, Neurons, Tyrosine hydroxylase, Stem Cells, Cell Cycle, Dopaminergic, Neurogenesis, Cell Differentiation, Cell Biology, Hematology, Fetal Blood, Phenotype, Culture Media, Rats, Cell biology, medicine.anatomical_structure, Immunology, Stem cell, Developmental Biology, Adult stem cell
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7b8a74da786e190a3269588703d19fc
https://doi.org/10.1089/scd.2007.0118 -
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المؤلفون: Niklas Feldhahn, Hans Werner Müller, Graça Almeida-Porada, Jizong Gao, Andreas Knipper, Jörg Bender, Markus Müschen, Claudia Rosenbaum, Judith A. Airey, Gesine Kögler, Özer Degistirici, Susanne Greschat, Esmail D. Zanjani, Peter Wernet, Arnold I. Caplan, Sandra Sensken, Johannes C. Fischer, Stefanie Liedtke, Evan Colletti, Thorsten Trapp, Rüdiger V. Sorg
المصدر: The Journal of Experimental Medicine
The Journal of experimental medicine, vol 200, iss 2مصطلحات موضوعية: Pathology, Umbilical Veins, Time Factors, Cell Transplantation, Cellular differentiation, Placenta, Wistar, Cell Culture Techniques, Medical and Health Sciences, Hippocampus, Polymerase Chain Reaction, 0302 clinical medicine, Leukocytes, Adipocytes, Immunology and Allergy, Developmental, Myocytes, Cardiac, CD45, Femur, 0303 health sciences, education.field_of_study, Neurotransmitter Agents, Blotting, Reverse Transcriptase Polymerase Chain Reaction, Stem Cells, Gene Expression Regulation, Developmental, Cell Differentiation, ex vivo expansion, Fetal Blood, Flow Cytometry, Cell biology, Haematopoiesis, Phenotype, 030220 oncology & carcinogenesis, Cord blood, cord blood, Cord Blood Stem Cell Transplantation, Stem cell, Cardiac, Western, Cell Division, Adult stem cell, medicine.medical_specialty, Population, Mononuclear, Immunology, Blotting, Western, regenerative medicine, Biology, Article, Bone and Bones, Cell Line, Immunophenotyping, 03 medical and health sciences, developmental potential, Albumins, medicine, Animals, Humans, Antigens, Rats, Wistar, education, 030304 developmental biology, Myocytes, Osteoblasts, Sheep, Myocardium, Hematopoietic Stem Cells, Rats, Transplantation, Gene Expression Regulation, Leukocytes, Mononuclear, Leukocyte Common Antigens
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a490907a67842888886cc9f903ed3d0
http://europepmc.org/articles/PMC2212008 -
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المؤلفون: Peter Ellinghaus, Karl-Heinz Thierauch, Ajay Bhargava, Holger Hess-Stumpp, Hartmut Beck, Susanne Greschat-Schade, Stephen Boyer, Kerstin Unterschemmann, Michael Härter
المصدر: ChemMedChem. 9(1)
مصطلحات موضوعية: Transcription, Genetic, Cell Survival, Cell, Administration, Oral, Pharmacology, Biology, Biochemistry, Transactivation, Structure-Activity Relationship, Cell Line, Tumor, Drug Discovery, medicine, Structure–activity relationship, Animals, Humans, General Pharmacology, Toxicology and Pharmaceutics, Gene, Transcription factor, Oxadiazoles, Organic Chemistry, medicine.disease, Hypoxia-Inducible Factor 1, alpha Subunit, Amides, Cell Hypoxia, Cell biology, Rats, medicine.anatomical_structure, Hypoxia-inducible factors, Apoptosis, Injections, Intravenous, Molecular Medicine, Adenocarcinoma, Pyrazoles, Half-Life
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المؤلفون: Antje Wengner, Peter Ellinghaus, Arne Scholz, Kerstin Berhoerster, Andrea Haegebarth, Michael Haerter, Susanne Greschat, Holger Hess-Stumpp
المصدر: Cancer Research. 71:4503-4503
مصطلحات موضوعية: Cancer Research, Pathology, medicine.medical_specialty, Chemotherapy, Tumor hypoxia, Bevacizumab, business.industry, medicine.medical_treatment, Hypoxia (medical), medicine.disease, Gemcitabine, Metastasis, Oncology, Neuroblastoma, Cancer research, medicine, Carcinoma, medicine.symptom, business, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::8b5ede0e01adcc1c7d439a12774a84e8
https://doi.org/10.1158/1538-7445.am2011-4503 -
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المؤلفون: Iring Heisler, Susanne Greschat, Scott Wilhelm, Holger Hess-Stumpp, Peter Ellinghaus, Kerstin Berhoerster, Michael Haerter, Oliver von Ahsen, Karl Ziegelbauer, Karl-Heinz Thierauch, Hartmut Beck
المصدر: Cancer Research. 71:4509-4509
مصطلحات موضوعية: Cancer Research, Tumor hypoxia, Biology, Hypoxia (medical), medicine.disease, Metastasis, Oncology, Downregulation and upregulation, Hypoxia-inducible factors, Tumor progression, Immunology, Cancer research, medicine, Protein stabilization, medicine.symptom, Transcription factor
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::4612305534d63566910d659ddfc43da0
https://doi.org/10.1158/1538-7445.am2011-4509 -
9دورية أكاديمية
المؤلفون: Susanne Greschat, Jessica Schira, Patrick Küry, Claudia Rosenbaum, Maria Angelica de Souza Silva, Gesine Kögler, Peter Wernet, Hans Werner Müller
المصدر: Stem Cells & Development; Apr2008, Vol. 17 Issue 2, p221-232, 12p
