المؤلفون: Julia Adler, Thomas Höfler, Volker Thiel, Luca D. Bertzbach, Joerg Jores, Azza Abdelgawad, Kristina Dietert, Andelé M. Conradie, Nadine Ebert, Fabien Labroussaa, Daria Vladimirova, Susanne Kaufer, Dusan Kunec, Achim D. Gruber, Tran Thi Nhu Thao, Jakob Trimpert, Nikolaus Osterrieder

المصدر: SSRN Electronic Journal.

مصطلحات موضوعية: Biosafety, Attenuated vaccine, business.industry, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Pandemic, Medicine, Disease, business, medicine.disease_cause, Virology, Genome, Virus, Coronavirus

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::829f0490112cea1aea88d650aec06abc
https://doi.org/10.2139/ssrn.3783405

المؤلفون: Volker Thiel, Tran Thi Nhu Thao, Julia Adler, Theresa C. Firsching, Jakob Trimpert, Nikolaus Osterrieder, Joerg Jores, Fabien Labroussaa, Susanne Kaufer, Dusan Kunec, Thomas Höfler, Achim D. Gruber, Azza Abdelgawad, Kristina Dietert, Nadine Ebert, Daria Vladimirova, Luca D. Bertzbach, Andelé M. Conradie

المصدر: Cell Reports
Trimpert, Jakob; Dietert, Kristina; Firsching, Theresa C; Ebert, Nadine; Tran, Thi Nhu Thao; Vladimirova, Daria; Kaufer, Susanne; Labroussaa, Fabien; Abdelgawad, Azza; Conradie, Andelé; Höfler, Thomas; Adler, Julia M; Bertzbach, Luca D; Jores, Jörg; Gruber, Achim D; Thiel, Volker; Osterrieder, Nikolaus; Kunec, Dusan (2021). Development of safe and highly protective live-attenuated SARS-CoV-2 vaccine candidates by genome recoding. Cell reports, 36(5), p. 109493. Cell Press 10.1016/j.celrep.2021.109493 <http://dx.doi.org/10.1016/j.celrep.2021.109493>

مصطلحات موضوعية: synthetic attenuated virus engineering, COVID-19 Vaccines, Syrian hamster, viruses, Respiratory System, coronavirus, 610 Medicine & health, Genome, Viral, Disease, Roborovski dwarf hamster, Vaccines, Attenuated, Virus Replication, medicine.disease_cause, Article, General Biochemistry, Genetics and Molecular Biology, Virus, Immunity, Chlorocebus aethiops, Pandemic, medicine, Animals, Humans, codon pair deoptimization, Pandemics, Vero Cells, Coronavirus, Gene Editing, live attenuated vaccine, Attenuated vaccine, 630 Agriculture, Mesocricetus, biology, business.industry, SARS-CoV-2, COVID-19, 500 Naturwissenschaften und Mathematik::570 Biowissenschaften, Biologie::570 Biowissenschaften, Biologie, biology.organism_classification, Virology, Viral replication, genome recoding, Mutation, 570 Life sciences, 590 Animals (Zoology), business

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b41ad2a1d3cb7ccdca98766f39f79ba

المؤلفون: Susanne Kaufer, Bastian Thaa, Bernadett Peibst, Eberhard Krause, Hans Nauwynck, Sara A. Neumann, Michael Veit

المصدر: Virus research. 240

مصطلحات موضوعية: 0301 basic medicine, Signal peptide, Cancer Research, Glycosylation, Swine, Amino Acid Motifs, Porcine Reproductive and Respiratory Syndrome, Biology, Protein Sorting Signals, Signal peptide processing, Epitope, 03 medical and health sciences, chemistry.chemical_compound, N-linked glycosylation, Viral Envelope Proteins, Virology, Animals, Porcine respiratory and reproductive syndrome virus, chemistry.chemical_classification, Signal peptidase, Porcine reproductive and respiratory syndrome virus, biology.organism_classification, Molecular biology, 030104 developmental biology, Infectious Diseases, chemistry, Glycoprotein, Protein Modification, Translational

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::640992bd424244e6f29b7423ec2c41d9
https://pubmed.ncbi.nlm.nih.gov/28807563

المؤلفون: Susanne Kaufer, John S. L. Parker, Caroline M. Coffey

المصدر: Journal of Virology. 86:1079-1089

مصطلحات موضوعية: Small interfering RNA, animal structures, Immunoprecipitation, Viral nonstructural protein, Amino Acid Motifs, Orthoreovirus, Mammalian, Immunology, Mutant, macromolecular substances, Viral Nonstructural Proteins, Biology, Microbiology, Inclusion bodies, Cell Line, Inclusion Bodies, Viral, Virology, Animals, Humans, Structure and Assembly, HSC70 Heat-Shock Proteins, Reoviridae Infections, Transport protein, Protein Transport, Cell culture, Insect Science, Chaperone (protein), embryonic structures, biology.protein, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0061271862e9090391d0cb6730eea41
https://doi.org/10.1128/jvi.02662-10

المؤلفون: Marci A. Scidmore, Joo-Yong Jung, Andrew M. Moorhead, Susanne Kaufer, Asya Smirnov

المصدر: Infection and immunity. 78(5)

مصطلحات موضوعية: Phosphatidylinositol 4-phosphate, Immunology, Chlamydiae, GTPase, Vacuole, Microbiology, Minor Histocompatibility Antigens, chemistry.chemical_compound, symbols.namesake, Phosphatidylinositol Phosphates, Humans, Chlamydia, Cellular Microbiology: Pathogen-Host Cell Molecular Interactions, biology, Bacteria, Intracellular parasite, Cell Membrane, Golgi apparatus, biology.organism_classification, Fusion protein, Phosphoric Monoester Hydrolases, Cell biology, Phosphotransferases (Alcohol Group Acceptor), Infectious Diseases, chemistry, Biochemistry, rab GTP-Binding Proteins, Vacuoles, symbols, Parasitology, ADP-Ribosylation Factor 1, Rab, HeLa Cells

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::467ba5d201d667b75e2106d94bedeb30
https://pubmed.ncbi.nlm.nih.gov/20231409