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1دورية أكاديمية
المؤلفون: Emma J Haagensen, Huw D Thomas, Ian Wilson, Suzannah J Harnor, Sara L Payne, Tommy Rennison, Kate M Smith, Ross J Maxwell, David R Newell
المصدر: PLoS ONE, Vol 8, Iss 12, p e81763 (2013)
وصف الملف: electronic resource
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2
المؤلفون: Duncan C. Miller, Suzannah J. Harnor, Mathew P. Martin, Richard A. Noble, Stephen R. Wedge, Celine Cano
المصدر: Journal of Medicinal Chemistry. 66:4491-4502
مصطلحات موضوعية: Drug Discovery, Molecular Medicine
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3
المؤلفون: Duncan C. Miller, Tristan Reuillon, Lauren Molyneux, Timothy Blackburn, Simon J. Cook, Noel Edwards, Jane A. Endicott, Bernard T. Golding, Roger J. Griffin, Ian Hardcastle, Suzannah J. Harnor, Amy Heptinstall, Pamela Lochhead, Mathew P. Martin, Nick C. Martin, Stephanie Myers, David R. Newell, Richard A. Noble, Nicole Phillips, Laurent Rigoreau, Huw Thomas, Julie A. Tucker, Lan-Zhen Wang, Michael J. Waring, Ai-Ching Wong, Stephen R. Wedge, Martin E. M. Noble, Celine Cano
المصدر: Journal of Medicinal Chemistry. 65:6513-6540
مصطلحات موضوعية: Drug Discovery, Molecular Medicine, Pyrroles, Mitogen-Activated Protein Kinase 7, Cell Proliferation
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المؤلفون: Lan Z. Wang, Miller Duncan Charles, Bernard T. Golding, Ian Hickson, Martin E.M. Noble, Celine Cano, Suzannah J. Harnor, Michael J. Waring, Harry J Shrives, Shaimaa Khalifa, Jane Totobenazara, Stephen J. Hobson, Elaine Willmore, Hannah L Stewart, Mathew P. Martin, Susan J. Tudhope, Huw D. Thomas, Islam Al-Khawaldeh, Claire E. Jennings, João V de Souza, Max J. Temple, Jane A. Endicott, Cinzia Bordoni, Honorine Lebraud, Agnieszka K. Bronowska, Ian R. Hardcastle, Amy B. Heptinstall, Stephen R. Wedge, Christine Basmadjian, Gregory G Aldred, Julie A. Tucker, Mohammed J Al Yasiri
المصدر: Journal of Medicinal Chemistry. 64:10001-10018
مصطلحات موضوعية: chemistry.chemical_classification, Dose-Response Relationship, Drug, Molecular Structure, biology, Chemistry, Kinase, Active site, Protein Serine-Threonine Kinases, Structure-Activity Relationship, Residue (chemistry), Pyrimidines, Enzyme, Biochemistry, Covalent bond, Alkynes, Drug Discovery, Cancer cell, biology.protein, Humans, Molecular Medicine, Kinome, Cysteine, Protein Kinase Inhibitors
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المؤلفون: Conghao Gai, Suzannah J. Harnor, Shihao Zhang, Céline Cano, Chunlin Zhuang, Qingjie Zhao
المصدر: RSC medicinal chemistry. 13(12)
مصطلحات موضوعية: Pharmacology, Organic Chemistry, Drug Discovery, Pharmaceutical Science, Molecular Medicine, Biochemistry
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82dcaba7fd742009e344a841265a95b8
https://pubmed.ncbi.nlm.nih.gov/36561076 -
6
المؤلفون: Benoit Carbain, Keisha Hearn, Ildiko Maria Buck, Burcu Anil, Sarah J. Cully, Gianni Chessari, Jane A. Endicott, John Lunec, Neil T. Thompson, Juan Castro, Roger J. Griffin, Rhian S. Holvey, Karen Haggerty, Charlotte H. Revill, Ruth H. Bawn, Stephen R. Wedge, Christiane Riedinger, Christopher N. Johnson, Bernard T. Golding, Lynsey Fazal, Ian R. Hardcastle, Mladen Vinkovic, Claire E. Jennings, Jong Sook Ahn, Bian Zhang, Pamela A. Williams, Celine Cano, Suzannah J. Harnor, Ben Cons, Stephen J. Hobson, E. Anscombe, Jeffrey D. St. Denis, Steven Howard, David R. Newell, Emiliano Tamanini, Nicola E. Wilsher, Miller Duncan Charles, Huw D. Thomas, Timothy J. Blackburn, Martin E.M. Noble, Judith Reeks, Yan Zhao, Luke Bevan
المصدر: Journal of Medicinal Chemistry. 64:4071-4088
مصطلحات موضوعية: Male, Metabolite, Mice, Nude, Antineoplastic Agents, Bone Neoplasms, Isoindoles, Pharmacology, Crystallography, X-Ray, 01 natural sciences, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, Drug Stability, In vivo, Cell Line, Tumor, Drug Discovery, Animals, Humans, Structure–activity relationship, neoplasms, Cell Proliferation, 030304 developmental biology, Mice, Inbred BALB C, Osteosarcoma, 0303 health sciences, Molecular Structure, biology, Chemistry, Proto-Oncogene Proteins c-mdm2, Ligand (biochemistry), Xenograft Model Antitumor Assays, Cytostasis, Small molecule, In vitro, 0104 chemical sciences, Macaca fascicularis, 010404 medicinal & biomolecular chemistry, Microsomes, Liver, biology.protein, Molecular Medicine, Mdm2, Female, Protein Multimerization, Tumor Suppressor Protein p53, Protein Binding
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7
المؤلفون: David Baker, Loranne Agius, Celine Cano, Suzannah J. Harnor, Rebecca J Fairclough, Alfie Brennan, Brian E. Ford, Shruti S. Chachra, David M. Smith, Ahmed Alshawi
مصطلحات موضوعية: medicine.anatomical_structure, business.industry, Hepatocyte, medicine, Glucokinase activator, Substrate (chemistry), business, Carbohydrate-responsive element-binding protein, Homeostasis, Cell biology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::42e90d6c07fc65ae63485a45d946240b
https://doi.org/10.1111/dom.14111/v2/response1 -
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المؤلفون: Alfie Brennan, Loranne Agius, David Baker, Ahmed Alshawi, Brian E. Ford, Celine Cano, Suzannah J. Harnor, Rebecca J Fairclough, David M. Smith, Shruti S. Chachra
المصدر: Diabetes, obesitymetabolismREFERENCES. 22(11)
مصطلحات موضوعية: G6PC, Endocrinology, Diabetes and Metabolism, Glucose-6-Phosphate, 030209 endocrinology & metabolism, 030204 cardiovascular system & hematology, Response Elements, 03 medical and health sciences, Mice, 0302 clinical medicine, Endocrinology, Adenosine Triphosphate, Gene expression, Glucokinase, Internal Medicine, medicine, Animals, Homeostasis, Carbohydrate-responsive element-binding protein, Protein kinase A, Glucose tolerance test, medicine.diagnostic_test, business.industry, Cell biology, Mice, Inbred C57BL, medicine.anatomical_structure, Glucose, Liver, Hepatocyte, Hepatocytes, business, Carrier Proteins
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المؤلفون: Kathy Boxall, Mangaleswaran Sivaprakasam, David P. Turner, Roger J. Griffin, Corine Mas-Droux, Benoit Carbain, Bernard T. Golding, Richard Bayliss, Ian R. Hardcastle, Mark W. Richards, Andrew M. Fry, Christopher R. Coxon, David R. Newell, Celine Cano, Suzannah J. Harnor, Christopher J. Matheson
المصدر: RSC Medicinal Chemistry
مصطلحات موضوعية: Pharmacology, Alanine, 0303 health sciences, 010405 organic chemistry, Stereochemistry, Organic Chemistry, Substituent, Pharmaceutical Science, macromolecular substances, 01 natural sciences, Biochemistry, 0104 chemical sciences, Chemistry, 03 medical and health sciences, chemistry.chemical_compound, chemistry, Covalent bond, Drug Discovery, Alkoxy group, Molecular Medicine, Structure–activity relationship, Growth inhibition, Acetamide, 030304 developmental biology, Cysteine
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae2f8ee1ed869eeee706983439e40721
https://pubmed.ncbi.nlm.nih.gov/33479670 -
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المؤلفون: Rodolfo Marquez, Christina Spry, Jonas Weber, Alan L. Sewell, Mathew V. J. Villa, Sheraz Gul, Suzannah J. Harnor, Yuliya Hering, Kevin J. Saliba, Stephen J. Hobson
المصدر: European Journal of Medicinal Chemistry. 143:1139-1147
مصطلحات موضوعية: 0301 basic medicine, Stereochemistry, Plasmodium falciparum, Seimatosporium, 01 natural sciences, Pantothenic Acid, Cofactor, Antimalarials, Structure-Activity Relationship, 03 medical and health sciences, Parasitic Sensitivity Tests, Drug Discovery, Humans, Moiety, Parasite hosting, Cell Proliferation, Pharmacology, Dose-Response Relationship, Drug, Molecular Structure, biology, 010405 organic chemistry, Chemistry, Organic Chemistry, General Medicine, biology.organism_classification, 0104 chemical sciences, Phosphotransferases (Alcohol Group Acceptor), 030104 developmental biology, Biochemistry, biology.protein, Pantothenate kinase, Phosphorylation
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8f9a2e34f7b8f96897f69a9aacee156
https://doi.org/10.1016/j .ejmech.2017.08.050