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1دورية أكاديمية
المؤلفون: Susan Wyllie, Adam J Roberts, Suzanne Norval, Stephen Patterson, Bernardo J Foth, Matthew Berriman, Kevin D Read, Alan H Fairlamb
المصدر: PLoS Pathogens, Vol 12, Iss 11, p e1005971 (2016)
مصطلحات موضوعية: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5
وصف الملف: electronic resource
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2دورية أكاديمية
المؤلفون: Stephen Patterson, Susan Wyllie, Suzanne Norval, Laste Stojanovski, Frederick RC Simeons, Jennifer L Auer, Maria Osuna-Cabello, Kevin D Read, Alan H Fairlamb
المصدر: eLife, Vol 5 (2016)
مصطلحات موضوعية: Leishmania donovani, Visceral leishmaniasis, drug repurposing, pharmacokinetics, pharmacodynamics, OPC-67683, Medicine, Science, Biology (General), QH301-705.5
وصف الملف: electronic resource
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3
المؤلفون: Michael G. Thomas, Maria L. Marco, John Thomas, Daniel Spinks, Ian H. Gilbert, Laste Stojanovski, Frederick R. C. Simeons, Ola Epemolu, Sujatha Manthri, Claire Naylor, Timothy J. Miles, Manu De Rycker, Suzanne Norval, Susan Wyllie, Stephen Patterson, Jennifer Riley, Maria Osuna-Cabello, Richard J. Wall, Jose M. Fiandor, Paul G. Wyatt, Kevin D. Read, Stephen Thompson
المصدر: Journal of Medicinal Chemistry. 63:9523-9539
مصطلحات موضوعية: 0303 health sciences, Chemistry, Pharmacology, medicine.disease, 01 natural sciences, Parasitic infection, In vitro, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, 03 medical and health sciences, Visceral leishmaniasis, In vivo, Drug Discovery, Toxicity, medicine, Molecular Medicine, Water chemistry, Structure–activity relationship, Inhibitory concentration 50, 030304 developmental biology
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4
المؤلفون: Kevin D. Read, Sabrinia D. Crouch, Juan Miguel-Siles, Stephen Thompson, Lorna MacLean, Timothy J. Miles, Franck Martin, Alain Claude-Marie Daugan, Suzanne Norval, Laste Stojanovski, Gloria Fra, John Thomas, Frederick R. C. Simeons, Sujatha Manthri, Jose M. Fiandor, César Guerrero, Myriam Ajakane, Maria Osuna-Cabello, Paul G. Wyatt, Manu De Rycker, Lorna Campbell, Claire J. MacKenzie, Ian H. Gilbert, Jennifer Riley, Yoko Shishikura, Michael G. Thomas, Raul F. Velasco
المصدر: RSC Medicinal Chemistry. 11:1168-1177
مصطلحات موضوعية: Pharmacology, 0303 health sciences, 030306 microbiology, business.industry, Organic Chemistry, Pharmaceutical Science, medicine.disease, Biochemistry, 03 medical and health sciences, Visceral leishmaniasis, In vivo, Drug Discovery, medicine, Molecular Medicine, Identification (biology), business, 030304 developmental biology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::907889087930243eaf8e578bd0ada172
https://doi.org/10.1039/d0md00203h -
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المؤلفون: Stephan Meister, Vicky M. Avery, Yevgeniya Antonova-Koch, Elizabeth A. Winzeler, Benigno Crespo, David Waterson, Alan H. Fairlamb, Jennifer Riley, Neil R. Norcross, Laura M. Sanz, Irene Hallyburton, Julie A. Frearson, Ian H. Gilbert, Paul Willis, Francisco-Javier Gamo, Simon F. Campbell, Suzanne Norval, Maria Osuna-Cabello, Cristina de Cozar, Robert E. Sinden, David W. Gray, Sandra Duffy, Andrea Ruecker, Caroline Wilson, Michael J. Delves, Beatriz Baragaña, Daniel A. Fletcher, Kevin D. Read
المصدر: Chemmedchem
مصطلحات موضوعية: Plasmodium berghei, Plasmodium falciparum, malaria, hit optimization, 01 natural sciences, Biochemistry, Antimalarials, Mice, Structure-Activity Relationship, chemistry.chemical_compound, Parasitic Sensitivity Tests, Pharmacokinetics, Acetamides, Drug Discovery, medicine, Animals, Humans, Potency, Antimalarial Agent, antimalarial agents, General Pharmacology, Toxicology and Pharmaceutics, Pharmacology, Full Paper, Molecular Structure, biology, 010405 organic chemistry, Organic Chemistry, Full Papers, biology.organism_classification, Propanamide, 3. Good health, 0104 chemical sciences, aminoacetamides, 010404 medicinal & biomolecular chemistry, medicine.anatomical_structure, chemistry, Microsomes, Liver, Microsome, Molecular Medicine, Gamete, Selectivity, Plasmodium cynomolgi
وصف الملف: application/pdf
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6دورية أكاديمية
المؤلفون: Katrin Hack, Louise Reilly, Colin Palmer, Kevin D Read, Suzanne Norval, Robert Kime, Kally Booth, John Foerster
المصدر: PLoS ONE, Vol 7, Iss 5, p e37097 (2012)
وصف الملف: electronic resource
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7
المؤلفون: Justin R, Harrison, Stephen, Brand, Victoria, Smith, David A, Robinson, Stephen, Thompson, Alasdair, Smith, Kenneth, Davies, Ngai, Mok, Leah S, Torrie, Iain, Collie, Irene, Hallyburton, Suzanne, Norval, Frederick R C, Simeons, Laste, Stojanovski, Julie A, Frearson, Ruth, Brenk, Paul G, Wyatt, Ian H, Gilbert, Kevin D, Read
المصدر: Journal of Medicinal Chemistry
مصطلحات موضوعية: Models, Molecular, Molecular Structure, Cell Survival, Protein Conformation, Trypanosoma brucei brucei, Mice, Inbred Strains, Trypanocidal Agents, Article, Mice, Structure-Activity Relationship, Trypanosomiasis, African, Blood-Brain Barrier, Drug Design, Animals, Humans, Female, Acyltransferases
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المؤلفون: Tracy, Bayliss, David A, Robinson, Victoria C, Smith, Stephen, Brand, Stuart P, McElroy, Leah S, Torrie, Chido, Mpamhanga, Suzanne, Norval, Laste, Stojanovski, Ruth, Brenk, Julie A, Frearson, Kevin D, Read, Ian H, Gilbert, Paul G, Wyatt
المصدر: Journal of Medicinal Chemistry
مصطلحات موضوعية: Sulfonamides, Trypanosoma brucei brucei, Aminopyridines, Brain, Crystallography, X-Ray, Trypanocidal Agents, Article, Mice, Trypanosomiasis, African, Drug Design, parasitic diseases, Animals, Humans, Enzyme Inhibitors, Acyltransferases
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المؤلفون: Meghan R. Perry, Suzanne Norval, Susan Wyllie, Kevin D. Read, Alan H. Fairlamb, Laste Stojanovski, Frederick R. C. Simeons, Manu De Rycker, Stephen Patterson, Maria Osuna-Cabello
المصدر: Antimicrobial Agents and Chemotherapy
مصطلحات موضوعية: Antiprotozoal Agents, Antitubercular Agents, Leishmania donovani, Biology, Pharmacology, Mycobacterium tuberculosis, Mice, 03 medical and health sciences, chemistry.chemical_compound, In vivo, medicine, Animals, Experimental Therapeutics, Pharmacology (medical), Nifurtimox, 030304 developmental biology, Mice, Inbred BALB C, 0303 health sciences, 030306 microbiology, Stereoisomerism, Prodrug, medicine.disease, biology.organism_classification, Leishmania, 3. Good health, Infectious Diseases, Visceral leishmaniasis, chemistry, Nitroimidazoles, Leishmaniasis, Visceral, Female, medicine.drug, Fexinidazole
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0f039088b6e0a73458004717369d610
https://doi.org/10.1128/aac.00722-13 -
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المؤلفون: Karen L. White, Paul G. Wyatt, Suzanne Norval, Marcel Kaiser, Ian H. Gilbert, Clive Yeates, Dinakaran Murugesan, Jennifer Riley, Susan A. Charman, Kevin D. Read
المصدر: Chemmedchem
مصطلحات موضوعية: Plasmodium falciparum, malaria, Drug Resistance, Drug resistance, Biology, Pharmacology, 010402 general chemistry, 01 natural sciences, Biochemistry, chemistry.chemical_compound, Antimalarials, Mice, Structure-Activity Relationship, Chloroquine, Drug Discovery, medicine, Structure–activity relationship, Animals, Pyrroles, Antimalarial Agent, General Pharmacology, Toxicology and Pharmaceutics, 010405 organic chemistry, Organic Chemistry, Full Papers, biology.organism_classification, pyrrolones, In vitro, 0104 chemical sciences, 3. Good health, Pyrimethamine, chemistry, Microsomes, Liver, Molecular Medicine, structure–activity relationships, Piperidine, antiprotozoal agents, medicine.drug, Half-Life