المؤلفون: Svenja M. Sake, Xiaoyu Zhang, Manoj Kumar Rajak, Melanie Urbanek-Quaing, Arnaud Carpentier, Antonia P. Gunesch, Christina Grethe, Alina Matthaei, Jessica Rückert, Marie Galloux, Thibaut Larcher, Ronan Le Goffic, Fortune Hontonnou, Arnab K. Chatterjee, Kristen Johnson, Kaycie Morwood, Katharina Rox, Walid A. M. Elgaher, Jiabin Huang, Martin Wetzke, Gesine Hansen, Nicole Fischer, Jean-Francois Eléouët, Marie-Anne Rameix-Welti, Anna K. H. Hirsch, Elisabeth Herold, Martin Empting, Chris Lauber, Thomas F. Schulz, Thomas Krey, Sibylle Haid, Thomas Pietschmann

المصدر: Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/66d08a2bbc3740f4a9e811166d229bd4

المؤلفون: Svenja M. Sake, Christina Kosch, Sebastian Blockus, Sibylle Haid, Antonia P. Gunesch, Xiaoyu Zhang, Martina Friesland, Sofie B. Trummer, Christina Grethe, Anne Kühnel, Jessica Rückert, W. Paul Duprex, Jiabin Huang, Marie-Anne Rameix-Welti, Martin Empting, Nicole Fischer, Anna K. H. Hirsch, Thomas F. Schulz, Thomas Pietschmann

المساهمون: HAL UVSQ, Équipe, Institute for Experimental Virology [Hanovre, Allemagne], Centre for Experimental and Clinical Infection Research (TWINCORE), Helmholtz Centre for Infection Research (HZI)-Medizinische Hochschule Hannover (MHH)-Helmholtz Centre for Infection Research (HZI)-Medizinische Hochschule Hannover (MHH), Helmholtz Centre for Infection Research (HZI), Saarland University [Saarbrücken], Medizinische Hochschule Hannover (MHH), German Centre for Infection Research (DZIF), University of Pittsburgh (PITT), Pennsylvania Commonwealth System of Higher Education (PCSHE), Universitaetsklinikum Hamburg-Eppendorf = University Medical Center Hamburg-Eppendorf [Hamburg] (UKE), Infection et inflammation (2I), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Institut National de la Santé et de la Recherche Médicale (INSERM), Hôpital Ambroise Paré [AP-HP], 11-76251-99-6/19, 14-76103-184 CORONA-13/ 20, ZN3437, Deutsches Zentrum für Infektionsforschung, DZIF, Deutsche Forschungsgemeinschaft, DFG: 390874280, EXC 2155, The purchase of the compound library and screening platform was made possible through financial support from the German Centre for Infection Research (DZIF) within the framework of the Translational Infrastructure ‘Novel Antivirals.’, A.K.H.H., T.P., and T.F.S. are funded by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) under the Germany’s Excellence Strategy EXC 2155 'RESIST' (Project ID 390874280) T.P. and T.F.S. are funded by the SARS-CoV-2 Immediate Response Initiative funded by the State of Lower Saxony (14-76103-184 CORONA-13/ 20). T.P. is also funded by the INDIRA Project (11-76251-99-6/19 (ZN3437). T.P. and A.K.H.H. also received funds from the Helmholtz International Lab for anti-infectives, and T.F.S. and T.P. are funded by the German Centre for Infection Research (DZIF).

المصدر: Antimicrobial Agents and Chemotherapy
Antimicrobial Agents and Chemotherapy, 2022, 66 (12), ⟨10.1128/aac.01032-22⟩

مصطلحات موضوعية: [SDV] Life Sciences [q-bio], Pharmacology, antivirals, Infectious Diseases, [SDV]Life Sciences [q-bio], RSV, Pharmacology (medical), drug screen, drug discovery

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17793939e21856df2d248a24962e93a5
https://pubmed.ncbi.nlm.nih.gov/36346232

المؤلفون: Jennifer Risso-Ballester, Marie Galloux, Jingjing Cao, Ronan Goffic, Fortune Hontonnou, Aude Jobart-Malfait, Aurore Desquesnes, Svenja M. Sake, Sibylle Haid, Miaomiao Du, Xiumei Zhang, Huan

المصدر: Nature, Nature. 595(7868):596-599

الإتاحة: https://ideas.repec.org/a/nat/nature/v595y2021i7868d10.1038_s41586-021-03703-z.html

المؤلفون: Thomas F. Schulz, Alina Matthaei, Thomas Pietschmann, Ursula Bilitewski, Tu-Trinh Nguyen, Antonia P Gunesch, Lisa Lasswitz, Francisco Zapatero, Svenja M. Sake, Sibylle Haid, Jessica Rueckert, Gabrielle Vieyres, Graham Brogden, Gisa Gerold, Mark Broenstrup, David Kuehl, Melina Winkler, Bettina Wiegmann

مصطلحات موضوعية: Broad spectrum, biology, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Molecular targets, medicine, biology.protein, Computational biology, Bardoxolone, medicine.disease_cause, Ligand (biochemistry), Aryl hydrocarbon receptor, Repurposing, Coronavirus

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::6f833693ca82c2960b6f9db2c20f4c3f
https://doi.org/10.1101/2021.07.14.452343

المؤلفون: Zhaoguo Wang, Ronan Le Goffic, Jean-François Eléouët, Ralf Altmeyer, Jennifer Risso-Ballester, Cao Jingjing, Miaomiao Du, Sibylle Haid, Marie Galloux, Huanyun Zhang, Aurore Desquesnes, Youming Zhang, Thomas Pietschmann, Fortune Hontonnou, Vincent Rincheval, Aude Jobart-Malfait, Svenja M. Sake, Marie-Anne Rameix-Welti, Xiumei Zhang

المساهمون: Infection et inflammation (2I), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Institut National de la Santé et de la Recherche Médicale (INSERM), Virologie et Immunologie Moléculaires (VIM (UR 0892)), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Université Paris-Saclay-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Shandong University, Centre for Experimental and Clinical Infection Research (TWINCORE), Helmholtz Centre for Infection Research (HZI)-Medizinische Hochschule Hannover (MHH), Qingdao Municipal Center for Disease Control and Prevention, Partenaires INRAE, Hôpital Ambroise Paré [AP-HP], The University of Hong Kong (HKU), Fondation Air Liquide, China - 111 Project B16030, ATIP-AVENIR INSERM and Fondation Del Duca-Institut de France, People’s Livelihood Technology Project of Qingdao City (17-3-3-2-nsh), Ile de France region (SESAME), Natural Science Foundation of China Youth Project (31900147), Sino-German Helmholtz International Lab grant (10000089395401), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Versailles Saint-Quentin-en-Yvelines (UVSQ), Région Île-de-France, Natural Science Foundation of China Youth Project: 31900147, Fondation Air Liquide, Ministry of Education, China - 111 Project: B16030, ATIP-AVENIR INSERM program, Fondation Del Duca-Institut de France grant, Sino-German Helmholtz International Lab grant: 10000089395401, People's Livelihood Technology Project of Qingdao City: 17-3-3-2-nsh, Le Goffic, Ronan

المصدر: Nature
Nature, Nature Publishing Group, 2021, 595 (7868), pp.596-599. ⟨10.1038/s41586-021-03703-z⟩

مصطلحات موضوعية: 0303 health sciences, Multidisciplinary, Cyclopamine, Point mutation, viruses, RNA, Inclusion bodies, Virus, 3. Good health, Cell biology, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, [SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitology, chemistry, Viral replication, In vivo, [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases, [SDV.MHEP.MI] Life Sciences [q-bio]/Human health and pathology/Infectious diseases, Transcription factor, 030217 neurology & neurosurgery, 030304 developmental biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b15795ad12cbd2ca05cfb9f41da330d
https://hal.inrae.fr/hal-03318345

المؤلفون: Qinggong Yuan, Glenn Randall, Alexander Ploss, Dorothea Bankwitz, Chris Lauber, Tanvi Khera, Florian W. R. Vondran, Zoltán Ivics, Thomas Krey, Gabrielle Vieyres, Eleftherios Michailidis, Julie Sheldon, Eike Steinmann, Svenja M. Sake, Anggakusuma, Lieven Verhoye, Natascha Goedecke, Charles M. Rice, Birthe Tegtmeyer, Kathrin Welsch, Yudi Zhang, Gisa Gerold, Dagmar Wirth, Csaba Miskey, Michael Engelmann, Daniel Todt, Sebastian Joecks, Viet Loan Dao Thi, Yasmine Baktash, Philip Meuleman, Wolfgang Baumgärtner, Vanessa Herder, Thomas Pietschmann, C. Patrick McClure, Mohsan Saeed, Michael Ott, Romy Weller, Michael Seifert, Corinne Ginkel, Alexander W. Tarr, Richard J. C. Brown, Luisa J Ströh

المصدر: Science Advances
eabd3233
Science advances, 6:eabd3233
SCIENCE ADVANCES

مصطلحات موضوعية: Genetically modified mouse, Permissiveness, Infectious Medicine, genetic structures, viruses, Hepatitis C virus, Medizin, Mice, Transgenic, Infektionsmedicin, Hepacivirus, Biology, medicine.disease_cause, Microbiology in the medical area, Mice, 03 medical and health sciences, 0302 clinical medicine, Interferon, Immunity, Virology, REVEALS, Medicine and Health Sciences, Mikrobiologi inom det medicinska området, medicine, Animals, Gene, Research Articles, 030304 developmental biology, 0303 health sciences, ROLES, Multidisciplinary, RECEPTOR, SciAdv r-articles, Life Sciences, Virus Internalization, Hepatitis C, digestive system diseases, medicine.anatomical_structure, Hepatocyte, REPLICATION, ENTRY, GROWTH, 030211 gastroenterology & hepatology, Ectopic expression, Research Article, medicine.drug

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::428abf72dcd16f6928f5ca0b922e1408
https://doi.org/10.1126/sciadv.abd3233

المؤلفون: Jennifer, Risso-Ballester, Marie, Galloux, Jingjing, Cao, Ronan, Le Goffic, Fortune, Hontonnou, Aude, Jobart-Malfait, Aurore, Desquesnes, Svenja M, Sake, Sibylle, Haid, Miaomiao, Du, Xiumei, Zhang, Huanyun, Zhang, Zhaoguo, Wang, Vincent, Rincheval, Youming, Zhang, Thomas, Pietschmann, Jean-François, Eléouët, Marie-Anne, Rameix-Welti, Ralf, Altmeyer

المصدر: Nature Reviews. Molecular Cell Biology

مصطلحات موضوعية: Biomolecular Condensates, Inclusion Bodies, Mice, Inbred BALB C, SARS-CoV-2, viruses, fungi, Veratrum Alkaloids, food and beverages, virus diseases, respiratory system, Virus Replication, Antiviral Agents, Research Highlight, Cell Line, Mice, Viral Proteins, Viral infection, Respiratory Syncytial Virus, Human, Animals, Humans, Female, Lung, Transcription Factors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::fb0edc58a046b7e5d2dd881c2d687e3f
https://pubmed.ncbi.nlm.nih.gov/34262155

المؤلفون: Gesine Hansen, Jean-François Eléouët, Marie Galloux, Hans Prochnow, Sebastian Blockus, Mark Brönstrup, Thomas Pietschmann, Theresa Graalmann, Sibylle Haid, Zeljka Rupcic, Martin Wetzke, Marina Pils, Ronald Dijkman, Ronan Le Goffic, Bettina Wiegmann, Katharina Rox, Stephan Hüttel, Svenja M. Sake, W. Paul Duprex, Volker Thiel, Marie-Anne Rameix-Welti, Christina Grethe

المساهمون: TWINCORE, Zentrum für experimentelle und klinische Infektionsforschung GmbH,Feodor-Lynen Str. 7, 30625 Hannover, Germany., Centre for Experimental and Clinical Infection Research (TWINCORE), Helmholtz Centre for Infection Research (HZI)-Medizinische Hochschule Hannover (MHH), Institute for Experimental Virology [Hanovre, Allemagne], Helmholtz Centre for Infection Research (HZI)-Medizinische Hochschule Hannover (MHH)-Helmholtz Centre for Infection Research (HZI)-Medizinische Hochschule Hannover (MHH), Hannover Medical School [Hannover] (MHH), German Center for Infection Research - partner site Hannover-Braunschweig (DZIF), Institute for Experimental Infection Research, Centre for Experimental and Clinical Infection Research [Hanover] (TWINCORE), Helmholtz Centre for Infection Research (HZI), Virologie et Immunologie Moléculaires (VIM (UR 0892)), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Université Paris-Saclay-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Department of Chemical Biology, German Research Centre for Biotechnology, Institute of Virology and Immunology [Mittelhäusern] (IVI), University of Bern, Infection et inflammation (2I), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Institut National de la Santé et de la Recherche Médicale (INSERM), National Emerging Infectious Diseases Laboratories (NEIDL), Boston University [Boston] (BU), Supported by the Innovation Fonds of the Helmholtz Association, by the Pre-4D-Fonds of the Helmholtz Centre for Infection Research, and by the Helmholtz-Alberta Initiative for Infectious Disease Research (HAI-IDR), Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) under Germany's Excellence Strategy – EXC 2155 'RESIST' – Project ID 39087428., Clinical leave scholarship from the German Centre for Infection Research (DZIF), Scholarship from the Young Academy of Hannover Medical School, Swiss National Science Foundation (grants 310030_179260 and 310030_173085)

المصدر: Blockus, Sebastian; Sake, Svenja M; Wetzke, Martin; Grethe, Christina; Graalmann, Theresa; Pils, Marina; Le Goffic, Ronan; Galloux, Marie; Prochnow, Hans; Rox, Katharina; Hüttel, Stephan; Rupcic, Zeljka; Wiegmann, Bettina; Dijkman, Ronald; Rameix-Welti, Marie-Anne; Eléouët, Jean-François; Duprex, W Paul; Thiel, Volker; Hansen, Gesine; Brönstrup, Mark; ... (2020). Labyrinthopeptins as virolytic inhibitors of respiratory syncytial virus cell entry. Antiviral research, 177, p. 104774. Elsevier 10.1016/j.antiviral.2020.104774 <http://dx.doi.org/10.1016/j.antiviral.2020.104774>
Antiviral research
Netherlands
Antiviral Research
Antiviral Research, Elsevier Masson, 2020, 177, pp.104774. ⟨10.1016/j.antiviral.2020.104774⟩

مصطلحات موضوعية: 0301 basic medicine, [SDV]Life Sciences [q-bio], 030106 microbiology, Cell, 610 Medicine & health, Respiratory Syncytial Virus Infections, Antiviral Agents, Virus, Virolytic, Cell Line, Labyrinthopeptin, Lanthipeptide, 03 medical and health sciences, Virus entry, Mice, Therapeutic index, Bacteriocins, In vivo, Viral entry, Virology, medicine, Animals, Humans, Antiviral activity, Lung, Cells, Cultured, Pharmacology, Mice, Inbred BALB C, Respiratory tract infections, 630 Agriculture, business.industry, Viral membrane, Virus Internalization, 3. Good health, Human respiratory syncytial virus (hRSV), 030104 developmental biology, medicine.anatomical_structure, Respiratory Syncytial Virus, Human, 570 Life sciences, biology, Female, business, Ex vivo

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb486d538293196fff21b21c9b5350a0
https://boris.unibe.ch/145425/1/b145425.pdf

المؤلفون: Svenja M. Sake, Daniel B. Werz, Thomas Pietschmann, Peter G. Jones, Christoph Köllmann

المساهمون: TWINCORE, Zentrum für experimentelle und klinische Infektionsforschung GmbH,Feodor-Lynen Str. 7, 30625 Hannover, Germany.

المصدر: The Journal of organic chemistry
United States

مصطلحات موضوعية: Denticity, 010405 organic chemistry, Chemistry, Stereochemistry, Organic Chemistry, Nucleosides, Carbohydrate, 010402 general chemistry, 01 natural sciences, Antiviral Agents, Uridine, Virus, 0104 chemical sciences, Alkyl ether, chemistry.chemical_compound, Respiratory Syncytial Virus, Human, Humans, Respiratory system, Protecting group

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f32c67c100be28fae2eae9c57ea485db
https://pubmed.ncbi.nlm.nih.gov/32036652