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المؤلفون: Evert Homan, Esther Kroodsma, Cor J. Grol, Swier Copinga, Håkan Wikström, Lena Unelius, Nina Mohell
المساهمون: Groningen Research Institute of Pharmacy, Faculty of Science and Engineering
المصدر: Bioorganic & Medicinal Chemistry, 7(6), 1111-1121. PERGAMON-ELSEVIER SCIENCE LTD
Bioorganic & Medicinal Chemistry, 1111-1121. PERGAMON-ELSEVIER SCIENCE LTD
STARTPAGE=1111;ENDPAGE=1121;ISSN=1464-3391;TITLE=Bioorganic & Medicinal Chemistryمصطلحات موضوعية: Tetrahydronaphthalenes, AGONISTS, Stereochemistry, Dopamine Agents, Clinical Biochemistry, Pharmaceutical Science, CHO Cells, Hippocampus, Biochemistry, Structure-Activity Relationship, chemistry.chemical_compound, Serotonin Agents, Dopamine receptor D3, Cricetinae, Dopamine receptor D2, Amide, BINDING, Drug Discovery, Animals, Humans, Binding site, AGENTS, Receptor, Molecular Biology, AFFINITY, Receptors, Dopamine D2, DERIVATIVES, Chemistry, 2-aminotetralin, Organic Chemistry, Dopaminergic, Receptors, Dopamine D3, structure-affinity relationships, Ligand (biochemistry), 2-Aminotetralin, 2-AMINOTETRALINS, Rats, serotonin, Receptors, Serotonin, Benzamides, Molecular Medicine, dopamine, Receptors, Serotonin, 5-HT1
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المؤلفون: Lena Unelius, Cor J. Grol, Swier Copinga, Rolf Johansson, Nina Mohell, Evert Homan, Trees van der Veen, Jan-Pieter Hallema, Lotta Elfström, Håkan Wikström
المصدر: Bioorganic & Medicinal Chemistry. 6:2111-2126
مصطلحات موضوعية: Agonist, Tetrahydronaphthalenes, medicine.drug_class, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Transfection, Biochemistry, Mice, Structure-Activity Relationship, chemistry.chemical_compound, L Cells, Dopamine, Dopamine receptor D2, Salicylamides, Drug Discovery, medicine, Animals, Humans, Receptor, Molecular Biology, 8-Hydroxy-2-(di-n-propylamino)tetralin, Receptors, Dopamine D2, Chemistry, 8-OH-DPAT, Organic Chemistry, Receptors, Dopamine D3, 2-Aminotetralin, Rats, Serotonin Receptor Agonists, Kinetics, Raclopride, Drug Design, Receptors, Serotonin, Benzamides, Dopamine Agonists, Molecular Medicine, 5-HT1A receptor, Receptors, Serotonin, 5-HT1, Endogenous agonist, Antipsychotic Agents, medicine.drug
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المؤلفون: R.A de Zeeuw, Jp Franke, U Selditz, Swier Copinga, Håkan Wikström
المساهمون: Faculty of Science and Engineering
المصدر: Chirality, 574-578. Wiley
STARTPAGE=574;ENDPAGE=578;TITLE=Chiralityمصطلحات موضوعية: Pharmacology, Hydrogen bond, Silica gel, Organic Chemistry, Substituent, Catalysis, Analytical Chemistry, Chiral column chromatography, Cellulose triacetate, chemistry.chemical_compound, chemistry, Asymmetric carbon, Drug Discovery, Organic chemistry, Racemic mixture, Enantiomer, Spectroscopy
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87270a6cea01f074d03d4fbe2af60a7c
https://doi.org/10.1002/(sici)1520-636x(1996)8:8<574::aid-chir6>3.0.co;2-9 -
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المؤلفون: Roland Isaksson, Cor J. Grol, Swier Copinga, Johanna M. Jansen, Dirk T. Witte, Gert Gruppen
المصدر: Chirality, 6(7), 596-604. Wiley
مصطلحات موضوعية: Steric effects, TRI-ACETYLCELLULOSE, MELATONIN, SEMIPREPARATIVE SEPARATION, Resolution (mass spectrometry), ENANTIOMERS, Receptors, Melatonin, CHROMATOGRAPHY, Receptors, Cell Surface, Melatonin receptor, BINDING-SITES, Catalysis, Analytical Chemistry, Structure-Activity Relationship, chemistry.chemical_compound, 2-AMIDOTETRALINS, Drug Discovery, RETENTION, Binding site, Cellulose, Chromatography, High Pressure Liquid, Spectroscopy, STEREOCHEMISTRY, Pharmacology, Binding Sites, Chromatography, Series (mathematics), Chemistry, Organic Chemistry, RECOGNITION, Stereoisomerism, PERFORMANCE LIQUID-CHROMATOGRAPHY, Cellulose triacetate, POLYAMIDES, RESOLUTION, Melatonin binding, Indicators and Reagents, CELLULOSE TRIACETATE, DRUG-ACTION, Enantiomer, TRIACETYLCELLULOSE
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المصدر: Journal of Medicinal Chemistry, 36(20), 2891-2898. AMER CHEMICAL SOC
مصطلحات موضوعية: Agonist, Tetrahydronaphthalenes, Stereochemistry, medicine.drug_class, Dopamine, Receptors, Melatonin, INHIBITION, Receptors, Cell Surface, Binding, Competitive, Melatonin receptor, Retina, IODINATED MELATONIN, Iodine Radioisotopes, Melatonin, Structure-Activity Relationship, Pineal gland, PHARMACOLOGICAL CHARACTERISTICS, Drug Discovery, medicine, Animals, Potency, HAMSTER BRAIN, Receptor, IC50, ANALOGS, Chemistry, Cell Membrane, Biological activity, RECEPTOR AGONISTS, TISSUE-CULTURE, PINEAL-GLAND, medicine.anatomical_structure, Molecular Medicine, Calcium, Rabbits, CHICKEN RETINA, Chickens, 2-
IODOMELATONIN BINDING-SITES , medicine.drug -
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المؤلفون: Jan B. De Vries, Cor J. Grol, Swier Copinga, Alan S. Horn, Durk Dijkstra
المصدر: Recueil des Travaux Chimiques des Pays-Bas-Journal of the Royal Netherlands Chemical Society, 112(2), 137-142. ELSEVIER SCIENCE BV
مصطلحات موضوعية: Agonist, STIMULATION, N-0437 [H-3] SCH 23390, medicine.drug_class, Stereochemistry, ENANTIOMERS, chemistry.chemical_compound, N-0437, Dopamine receptor D2, BINDING, medicine, Trifluoroacetic acid, D-1, [H-3] SPIPERONE, SCH-23390, POTENT, Dopaminergic, N-DISUBSTITUTED 2-AMINOTETRALINS, RESERPINE, STRIATAL DOPAMINE, General Chemistry, Reserpine, Ligand (biochemistry), D2-RECEPTOR AGONIST, RHODIUM(II)-ACETATECATALYSED CYCLIZATION, chemistry, MIXED D1, Dopamine receptor, LIGAND, N,N-DISUBSTITUTED 2-AMINOTETRALINS, SKF 38393, medicine.drug
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المؤلفون: J. B. De Vries, As Horn, Cor J. Grol, Swier Copinga, Durk Dijkstra
المصدر: ChemInform. 24
مصطلحات موضوعية: Agonist, Dopamine receptor, Stereochemistry, medicine.drug_class, Chemistry, medicine, General Medicine, Thiophene derivatives
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المؤلفون: Cor J. Grol, Swier Copinga, Bhc Westerink, H.F Brons, Evert Homan, J. B. De Vries, Isabel J. M. Beresford, Gert Gruppen, R.M. Hagan, W. J. Drijfhout
المساهمون: Faculty of Science and Engineering, Biomonitoring and Sensoring
المصدر: European Journal of Pharmacology, 382(3), 157-166. ELSEVIER SCIENCE BV
مصطلحات موضوعية: Agonist, Male, endocrine system, Microdialysis, medicine.medical_specialty, Indoles, Time Factors, Tetrahydronaphthalenes, medicine.drug_class, entrainment, Receptors, Melatonin, Receptors, Cytoplasmic and Nuclear, Receptors, Cell Surface, Biology, Melatonin receptor, Pineal Gland, SUBTYPES, Melatonin, IN-VIVO MICRODIALYSIS, Pineal gland, RAT PINEAL-GLAND, PERIIMPLANTATION, HORMONE, melatonin receptor agonist, Internal medicine, medicine, Animals, Circadian rhythm, Rats, Wistar, RETINA, Melatonin receptor agonist, Chromatography, High Pressure Liquid, amplitude, Pharmacology, RELEASE, Chronobiology, SPOTTED SKUNK, PINEALECTOMIZED RATS, Circadian Rhythm, Rats, Endocrinology, medicine.anatomical_structure, Indans, SECRETION, hormones, hormone substitutes, and hormone antagonists, medicine.drug
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المؤلفون: Evert Homan, Lena Unelius, David M. Jackson, Cor J. Grol, Swier Copinga, H̊kan V. Wikström
المصدر: Bioorganicmedicinal chemistry. 7(7)
مصطلحات موضوعية: Male, Tertiary amine, Tetrahydronaphthalenes, Clinical Biochemistry, Dopamine Agents, Pharmaceutical Science, Pharmacology, Motor Activity, Biochemistry, Partial agonist, Rats, Sprague-Dawley, Inhibitory Concentration 50, Structure-Activity Relationship, Serotonin Agents, Isomerism, Dopamine receptor D3, Dopamine, Receptors, Adrenergic, alpha-2, Receptors, Adrenergic, alpha-1, Drug Discovery, Muscarinic acetylcholine receptor, Receptors, Adrenergic, beta, medicine, Cyclic AMP, Animals, Humans, Receptor, Molecular Biology, Cells, Cultured, Catalepsy, Chemistry, Receptors, Dopamine D2, Receptors, Dopamine D1, Organic Chemistry, Receptors, Dopamine D3, Rats, Amphetamine, Mechanism of action, Receptors, Serotonin, Benzamides, Remoxipride, Molecular Medicine, Serotonin, medicine.symptom, Receptors, Serotonin, 5-HT1, medicine.drug, Antipsychotic Agents, Vasoactive Intestinal Peptide
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المؤلفون: Margarita L. Dubocovich, Cor J. Grol, Swier Copinga, Eduardo J. Molinari, Johanna M. Jansen, Gert Gruppen
المصدر: Bioorganicmedicinal chemistry. 4(8)
مصطلحات موضوعية: Models, Molecular, Stereochemistry, Protein Conformation, Clinical Biochemistry, Receptors, Melatonin, Pharmaceutical Science, Receptors, Cytoplasmic and Nuclear, Receptors, Cell Surface, Biochemistry, Molecular mechanics, Melatonin receptor, chemistry.chemical_compound, Amide, Cricetinae, Drug Discovery, Animals, Molecular Biology, Melatonin, Binding Sites, Chemistry, Organic Chemistry, Stereoisomerism, Combinatorial chemistry, Affinities, Models, Chemical, Melatonin binding, Molecular Medicine, Stereoselectivity, Enantiomer, Pharmacophore, Software
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