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المؤلفون: Walden, M, Tian, L, Ross, RL, Sykora, UM, Byrne, DP, Hesketh, EL, Masandi, SK, Cassel, J, George, R, Ault, JR, El Oualid, F, Pawłowski, K, Salvino, JM, Eyers, PA, Ranson, NA, Del Galdo, F, Greenberg, RA, Zeqiraj, E
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المؤلفون: Walden M; Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, UK., Tian L; Department of Cancer Biology, Basser Center for BRCA, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Ross RL; Leeds Institute of Rheumatic and Musculoskeletal Medicine and NIHR Biomedical Research Centre, University of Leeds, Leeds, UK., Sykora UM; Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, UK., Byrne DP; Department of Biochemistry, Institute of Integrative Biology, University of Liverpool, Liverpool, UK., Hesketh EL; Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, UK., Masandi SK; Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, UK., Cassel J; The Wistar Cancer Center for Molecular Screening, The Wistar Institute, Philadelphia, PA, USA., George R; Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, UK., Ault JR; Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, UK., El Oualid F; UbiQ Bio BV, Amsterdam, The Netherlands., Pawłowski K; Warsaw University of Life Sciences, Warsaw, Poland.; Department of Translational Medicine, Clinical Sciences, Lund University, Lund, Sweden., Salvino JM; The Wistar Cancer Center for Molecular Screening, The Wistar Institute, Philadelphia, PA, USA., Eyers PA; Department of Biochemistry, Institute of Integrative Biology, University of Liverpool, Liverpool, UK., Ranson NA; Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, UK., Del Galdo F; Leeds Institute of Rheumatic and Musculoskeletal Medicine and NIHR Biomedical Research Centre, University of Leeds, Leeds, UK., Greenberg RA; Department of Cancer Biology, Basser Center for BRCA, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. rogergr@pennmedicine.upenn.edu., Zeqiraj E; Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, UK. e.zeqiraj@leeds.ac.uk.
المصدر: Nature [Nature] 2019 Jun; Vol. 570 (7760), pp. 194-199. Date of Electronic Publication: 2019 May 29.
نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE
مواضيع طبية MeSH: Deubiquitinating Enzymes/*metabolism , Glycine Hydroxymethyltransferase/*metabolism , Interferon Type I/*immunology , Multienzyme Complexes/*immunology , Multienzyme Complexes/*metabolism , Signal Transduction/*immunology, Cryoelectron Microscopy ; Deubiquitinating Enzymes/antagonists & inhibitors ; Deubiquitinating Enzymes/chemistry ; Deubiquitinating Enzymes/ultrastructure ; Glycine Hydroxymethyltransferase/ultrastructure ; HEK293 Cells ; Humans ; Inflammation/immunology ; Models, Molecular ; Multienzyme Complexes/chemistry ; Multienzyme Complexes/genetics ; Mutation ; Protein Binding ; Protein Multimerization ; Protein Structure, Quaternary ; Pyridoxal Phosphate/metabolism
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