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1دورية أكاديمية
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المؤلفون: Rita Guerreiro, Elizabeth Gibbons, Jose Bras
المصدر: Acta Neuropathologica. 141:471-490
مصطلحات موضوعية: 0301 basic medicine, Genetics, Synucleinopathies, education.field_of_study, Population, Locus (genetics), Disease, Biology, Pathology and Forensic Medicine, 03 medical and health sciences, Cellular and Molecular Neuroscience, 030104 developmental biology, 0302 clinical medicine, Synuclein Family, Synuclein, Neurology (clinical), Genetic variability, education, Gene, 030217 neurology & neurosurgery
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المؤلفون: Natalia Ninkina, Owen M. Peters, Natalie Connor-Robson, Kirill D. Chaprov, Holger B. Kramer, Dominic J. Withers, Arthur T. Kopylov, Vladimir L. Buchman, Steven Millership, Alex Montoya
المساهمون: Wellcome Trust ISSF Funding, Medical Research Council
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: MPTP toxicity, MPP+, 1-methyl-4-phenylpyridinium, animal diseases, Parkinson's disease, Dopamine, Vesicular monoamine transporter 2, Biochemistry, chemistry.chemical_compound, Mice, neurodegenerative disease, synapse, DAT, dopamine transporter, Synuclein Family, 11 Medical and Health Sciences, Mice, Knockout, vesicles, biology, Cell Death, MPTP, CLIP, crosslink immunoprecipitation, Dopaminergic, LFQ, label-free quantitation, PSM, peptide-spectrum match, Cell biology, SNpc, substantia nigra pars compacta, 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine, iBAQ, intensity-based absolute quantification, Synaptic Vesicles, 03 Chemical Sciences, TKO, triple α/β/γ-synuclein null mutant mice, Research Article, Biochemistry & Molecular Biology, FDR, false discovery rate, TH, tyrosine hydroxylase, MPTP, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine, Substantia nigra, transgenic mice, Synaptic vesicle, synuclein, beta-Synuclein, mental disorders, GO, Gene Ontology, Animals, Molecular Biology, AADC, aromatic l-amino acid decarboxylase, neurotransmitter vesicular uptake, dopaminergic neurons, Pars compacta, Cell Biology, 06 Biological Sciences, nervous system diseases, Vesicular monoamine transporter, chemistry, nervous system, VMAT-2, vesicular monoamine transporter 2, biology.protein, Parkinson’s disease, DTSSP, 3,3′-dithiobis(sulfosuccinimidylpropionate)
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92c25bdcdb04d42ed3e6e25fe31cef99
http://europepmc.org/articles/PMC8633583 -
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المؤلفون: Natalia Ninkina, Mikhail V. Pokrovskiy, Andrei Yu. Roman, Vladimir L. Buchman, Irina A. Guschina
المصدر: Molecules
Volume 26
Issue 11
Molecules, Vol 26, Iss 3078, p 3078 (2021)مصطلحات موضوعية: Pharmaceutical Science, Organic chemistry, fatty acids, Article, Analytical Chemistry, Palmitic acid, 03 medical and health sciences, chemistry.chemical_compound, Mice, 0302 clinical medicine, QD241-441, Biosynthesis, Phosphatidylcholine, synucleins, Drug Discovery, Synuclein Family, Animals, Physical and Theoretical Chemistry, Lipid raft, phospholipids, 030304 developmental biology, chemistry.chemical_classification, Mice, Knockout, 0303 health sciences, Brain, Lipid metabolism, non-polar lipids, Lipid Metabolism, Lipids, nervous system diseases, chemistry, Biochemistry, Liver, nervous system, Chemistry (miscellaneous), Synuclein, Molecular Medicine, triple-knockout mouse model, lipids (amino acids, peptides, and proteins), 030217 neurology & neurosurgery, Polyunsaturated fatty acid
وصف الملف: application/pdf
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المؤلفون: Geert Callewaert, Petra D’hooge, Tien-Yang Ma, Mara Del Vecchio, Vincent Van Eyck, Vanessa Franssens, Joris Winderickx
المصدر: Frontiers in Genetics, Vol 11 (2020)
مصطلحات موضوعية: 0301 basic medicine, lcsh:QH426-470, alpha-synuclein, animal diseases, ATPase, Saccharomyces cerevisiae, Aequorin, Ca2+ ATPase Pmc1, yeast, TOXICITY, 03 medical and health sciences, chemistry.chemical_compound, α-synuclein, 0302 clinical medicine, Genetics, Synuclein Family, YEAST-CELLS, PHOSPHORYLATION, MUTATION, Ca2+ signaling, Genetics (clinical), Genetics & Heredity, Alpha-synuclein, Science & Technology, biology, pore formation, Chemistry, SEC4 FUNCTION, DEFECTS, biology.organism_classification, CALCIUM INFLUX, nervous system diseases, Cell biology, MODEL, lcsh:Genetics, Cytosol, 030104 developmental biology, nervous system, 030220 oncology & carcinogenesis, vesicle trafficking, biology.protein, Molecular Medicine, SNARE COMPLEX, Life Sciences & Biomedicine, Homeostasis, Intracellular
وصف الملف: Electronic-eCollection
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fd743c5f9c2eae60c2fb935c5c7d023
https://doi.org/10.3389/fgene.2020.00266 -
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المؤلفون: R. K. Ovchinnikov, Sergey Morozov, Ekaterina V. Teterina, Kirill D. Chaprov, Valeria V. Goloborshcheva, Valeriayn Kucheryanu
المصدر: Neuroscience for Medicine and Psychology.
مصطلحات موضوعية: Chemistry, Toxin, Mechanism (biology), Dopaminergic, Synuclein Family, medicine, Substantia nigra, medicine.disease_cause, Cell biology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::823695987c65a352d852432371014d0b
https://doi.org/10.29003/m1325.sudak.ns2020-16/505-506 -
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المصدر: Biomolecules
Biomolecules, Vol 11, Iss 1067, p 1067 (2021)
Volume 11
Issue 8مصطلحات موضوعية: beta-synuclein, Protein Conformation, alpha-Helical, 0301 basic medicine, alpha-synuclein, Protein aggregation, Microbiology, Biochemistry, Article, Protein Structure, Secondary, Protein–protein interaction, Protein Aggregates, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, ddc:570, Synuclein Family, Humans, polarized ATR-FTIR, protein–membrane interaction, protein–protein interaction, Amino Acid Sequence, Lipid bilayer, Molecular Biology, Protein secondary structure, Alpha-synuclein, Parkinson Disease, QR1-502, 030104 developmental biology, chemistry, Synuclein, Biophysics, Beta-synuclein, 030217 neurology & neurosurgery, Protein Binding
وصف الملف: application/pdf
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المؤلفون: Ana Gámez-Valero, Katrin Beyer
المصدر: Genes
Genes, Vol 9, Iss 2, p 63 (2018)مصطلحات موضوعية: 0301 basic medicine, lcsh:QH426-470, Review, Biology, differential expression, 03 medical and health sciences, Exon, β-synuclein, alternative splicing, 0302 clinical medicine, α-synuclein, mental disorders, Genetics, medicine, Synuclein Family, Gene, Genetics (clinical), Synucleinopathies, Dementia with Lewy bodies, Alternative splicing, medicine.disease, nervous system diseases, lcsh:Genetics, 030104 developmental biology, nervous system, RNA splicing, Beta-synuclein, SNCA, functional splice variants, SNCB, 030217 neurology & neurosurgery
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المؤلفون: Alexei Surguchev, Andrei Surguchov
المصدر: Frontiers in Molecular Neuroscience, Vol 10 (2017)
Frontiers in Molecular Neuroscienceمصطلحات موضوعية: 0301 basic medicine, animal diseases, Review, Biology, Synaptic vesicle, epigenetic regulation, lcsh:RC321-571, 03 medical and health sciences, Cellular and Molecular Neuroscience, 0302 clinical medicine, synucleins, transcription factors, translation factors, Gene expression, Synuclein Family, Epigenetics, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, Molecular Biology, Gene, Transcription factor, Genetics, DNA methylation, histone modifications, neurodegeneration, nervous system diseases, 030104 developmental biology, Histone, nervous system, gene expression, Synuclein, biology.protein, 030217 neurology & neurosurgery, Neuroscience
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المؤلفون: Hao Deng, Lamei Yuan
المصدر: Ageing Research Reviews. 15:161-176
مصطلحات موضوعية: Aging, Disease, Biology, medicine.disease_cause, Biochemistry, Pathogenesis, Mice, Synuclein Family, medicine, Animals, Humans, Caenorhabditis elegans, Molecular Biology, Gene, Genetics, Mutation, Parkinsonism, Point mutation, Dopaminergic, Genetic Variation, Parkinson Disease, Haplorhini, medicine.disease, Rats, Disease Models, Animal, Neurology, alpha-Synuclein, Drosophila, Neuroscience, Biotechnology
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