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المؤلفون: Yassine Amrani, T J Torphy, Rebecca Hoffman, Aili L. Lazaar, Reynold A. Panettieri, Raymond B. Penn, Douglas W. P. Hay, Alaina J. Ammit
المصدر: American Journal of Respiratory Cell and Molecular Biology. 23:794-802
مصطلحات موضوعية: Pulmonary and Respiratory Medicine, medicine.medical_specialty, Time Factors, Cyclohexanecarboxylic Acids, Transcription, Genetic, Phosphodiesterase Inhibitors, medicine.medical_treatment, Clinical Biochemistry, Prostaglandin, Dinoprostone, chemistry.chemical_compound, Internal medicine, Nitriles, Cyclic AMP, medicine, Humans, Cyclic adenosine monophosphate, Secretion, RNA, Messenger, Interleukin 6, Chemokine CCL5, Molecular Biology, Cells, Cultured, Forskolin, Dose-Response Relationship, Drug, biology, Interleukin-6, Tumor Necrosis Factor-alpha, Colforsin, NF-kappa B, Interleukin, Muscle, Smooth, Cell Biology, Cyclic Nucleotide Phosphodiesterases, Type 4, Trachea, Cytokine, Endocrinology, Bucladesine, chemistry, 3',5'-Cyclic-AMP Phosphodiesterases, biology.protein, Tumor necrosis factor alpha
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2
المؤلفون: Rush Ja, Esser Km, L. B. Cieslinski, M S Barnette, T J Torphy, Burman M, Siegfried B. Christensen, Prabhakar Us, Bartus Jo
المصدر: Biochemical Pharmacology. 51:949-956
مصطلحات موضوعية: Pharmacology, Biochemistry, Radioligand Assay, medicine, Humans, Binding site, Rolipram, Dose-Response Relationship, Drug, biology, Phosphoric Diester Hydrolases, Tumor Necrosis Factor-alpha, Chemistry, Anti-Inflammatory Agents, Non-Steroidal, Phosphodiesterase, Biological activity, Pyrrolidinones, Cyclic Nucleotide Phosphodiesterases, Type 4, Mechanism of action, 3',5'-Cyclic-AMP Phosphodiesterases, Enzyme inhibitor, Myeloperoxidase, biology.protein, Neutrophil degranulation, medicine.symptom, medicine.drug
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3
المؤلفون: Henry M. Sarau, Han-Liang Zhou, Mary S. Barnette, Carol D. Manning, James J. Foley, T J Torphy
المصدر: Journal of Biological Chemistry. 270:23598-23604
مصطلحات موضوعية: Agonist, medicine.medical_specialty, Cyclic nucleotide phosphodiesterase, medicine.drug_class, Monocyte, Cell Biology, Biochemistry, Adenylyl cyclase, chemistry.chemical_compound, medicine.anatomical_structure, Endocrinology, PDE4B, chemistry, Cell culture, Internal medicine, medicine, Prostaglandin E2, Molecular Biology, Rolipram, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::0b4b13dc6563091eaeb1ede493f549c5
https://doi.org/10.1074/jbc.270.40.23598 -
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المؤلفون: G. P. Livi, A. R. Shatzman, L B Cieslinski, Lois L. Hoyer, M. M. Mclaughlin, T J Torphy
المصدر: Microbiology. 140:1533-1542
مصطلحات موضوعية: Cations, Divalent, Genes, Fungal, Molecular Sequence Data, Saccharomyces cerevisiae, Microbiology, Dictyostelium discoideum, law.invention, Species Specificity, law, Candida albicans, Cyclic AMP, Amino Acid Sequence, Cloning, Molecular, Cyclic GMP, Base Sequence, Sequence Homology, Amino Acid, biology, Cyclic nucleotide phosphodiesterase, Phosphoric Diester Hydrolases, Genetic Complementation Test, Nucleic acid sequence, Sequence Analysis, DNA, Cyclic Nucleotide Phosphodiesterases, Type 1, biology.organism_classification, Molecular biology, Recombinant Proteins, Corpus albicans, Complementation, Biochemistry, 3',5'-Cyclic-AMP Phosphodiesterases, Recombinant DNA
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12a1bc6a4426db2ce024961ab0b481c4
https://doi.org/10.1099/13500872-140-7-1533 -
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المؤلفون: A N Fonteh, J D Winkler, T J Torphy, J Heravi, B J Undem, F H Chilton
المصدر: The Journal of Immunology. 151:339-350
مصطلحات موضوعية: Immunology, Immunology and Allergy
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::87625adb1ac4a77db77962378a30308d
https://doi.org/10.4049/jimmunol.151.1.339 -
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المؤلفون: James J. Foley, Han-Liang Zhou, Marie Chabot-Fletcher, M. N. Tzimas, James D. Winkler, Henry M. Sarau, T. J. Torphy
المصدر: Biochemical Pharmacology. 46:139-148
مصطلحات موضوعية: Cytochalasin B, Neutrophils, Leukotriene B4, Biochemistry, Cell Degranulation, chemistry.chemical_compound, Alkaloids, Phospholipase D, medicine, Extracellular, Humans, Staurosporine, Protein kinase A, Protein Kinase C, Benzophenanthridines, Pharmacology, Dose-Response Relationship, Drug, Ethanol, Degranulation, hemic and immune systems, respiratory system, Propranolol, Molecular biology, biological factors, Phenanthridines, respiratory tract diseases, Enzyme Activation, Mechanism of action, chemistry, Calcium, lipids (amino acids, peptides, and proteins), medicine.symptom, Intracellular, medicine.drug
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المؤلفون: M Burman, L B Cieslinski, George P. Livi, Megan M. McLaughlin, T J Torphy
المصدر: Journal of Biological Chemistry. 268:6470-6476
مصطلحات موضوعية: chemistry.chemical_classification, Messenger RNA, cDNA library, Protein primary structure, Phosphodiesterase, Cell Biology, Biology, Biochemistry, Molecular biology, Amino acid, chemistry, Complementary DNA, Gene expression, medicine, Molecular Biology, Rolipram, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::1530e105122a0f3d04c116f0d44a5f62
https://doi.org/10.1016/s0021-9258(18)53275-0 -
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المؤلفون: D.W.P. Hay, M.A. Wasserman, T. J. Torphy, R.R. Osborn
المصدر: Pulmonary Pharmacology. 5:153-157
مصطلحات موضوعية: Male, Pulmonary and Respiratory Medicine, Leukotriene D4, Bronchoconstriction, Mepyramine, Pharmacology, chemistry.chemical_compound, Administration, Inhalation, medicine, Animals, Anesthesia, Dicarboxylic Acids, Pharmacology (medical), Antigens, Receptors, Immunologic, General Pharmacology, Toxicology and Pharmaceutics, Pyrilamine, Ascaris suum, Aerosols, Receptors, Leukotriene, Dose-Response Relationship, Drug, biology, Leukotriene receptor, Antagonist, biology.organism_classification, Macaca fascicularis, chemistry, Injections, Intravenous, SRS-A, medicine.symptom, Histamine, medicine.drug
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المؤلفون: P T Peachell, B J Undem, R P Schleimer, D W MacGlashan, L M Lichtenstein, L B Cieslinski, T J Torphy
المصدر: The Journal of Immunology. 148:2503-2510
مصطلحات موضوعية: Immunology, Immunology and Allergy
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::633ba8a89d8d16cfd324e1fff2f41a2e
https://doi.org/10.4049/jimmunol.148.8.2503 -
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المؤلفون: L. Vickery-Clark, R.M. Muccitelli, R.D. Eckardt, L.-A.P. Yodis, Henry M. Sarau, M.A. Wasserman, C.M. Saverino, John G. Gleason, T. J. Torphy, R.R. Osborn, J. F. Newton, L.S. Novak, D.W.P. Hay
المصدر: Pulmonary Pharmacology. 4:177-189
مصطلحات موضوعية: Male, Pulmonary and Respiratory Medicine, Phosphodiesterase Inhibitors, medicine.drug_class, Guinea Pigs, Thio, In Vitro Techniques, Pharmacology, Guinea pig, Pharmacokinetics, medicine, Animals, Dicarboxylic Acids, Pharmacology (medical), Receptors, Immunologic, General Pharmacology, Toxicology and Pharmaceutics, Lung, Receptors, Leukotriene, Leukotriene receptor, Chemistry, Antagonist, Muscle, Smooth, Receptor antagonist, Pathophysiology, Bioavailability, Trachea, SRS-A, Muscle Contraction