المؤلفون: Katherine L. Williams, Yevel Flores-Garcia, David Oyen, Daniel Emerling, Emily Locke, Fidel Zavala, T. Pholcharee, Zhen Han, Wayne Volkmuth, C. Richter King, Gonzalo E. González-Páez, Ian A. Wilson

المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Nature Communications

مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, Repetitive Sequences, Amino Acid, Science, Amino Acid Motifs, Plasmodium falciparum, Antibody Affinity, General Physics and Astronomy, Antibodies, Protozoan, Plasma protein binding, Crystallography, X-Ray, General Biochemistry, Genetics and Molecular Biology, Epitope, Article, Antibodies, 03 medical and health sciences, Epitopes, Immunoglobulin Fab Fragments, 0302 clinical medicine, In vivo, parasitic diseases, Animals, Parasites, 030212 general & internal medicine, Amino Acid Sequence, Malaria, Falciparum, Structural motif, X-ray crystallography, Multidisciplinary, biology, Chemistry, Malaria vaccine, Antibody titer, General Chemistry, Virology, Circumsporozoite protein, Mice, Inbred C57BL, Kinetics, 030104 developmental biology, biology.protein, Antibody, Peptides, Protein Binding, Parasite host response

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cffcde9eccecc01a75ed6ba87e713124
https://doaj.org/article/f69e762087b34c9ba0a1c8a3d1c005e9

المؤلفون: Yevel Flores-Garcia, Daniel Emerling, Fidel Zavala, Emily Locke, Jonathan L. Torres, C. R. King, T. Pholcharee, David Oyen, Ian A. Wilson, Wayne Volkmuth, Andrew B. Ward, Martin Gm, Gonzalo E. González-Páez

المصدر: Journal of Molecular Biology

مصطلحات موضوعية: Protozoan Proteins, Antibodies, Protozoan, type I β-turn, Germline, Epitopes, Mice, 0302 clinical medicine, Structural Biology, BLI, biolayer interferometry, Malaria, Falciparum, Structural motif, Trp-Asn interaction, BSA, buried surface area, Genetics, 0303 health sciences, ITC, isothermal titration calorimetry, Malaria vaccine, Fab, fragment of antigen binding, Circumsporozoite protein, Sporozoites, Female, nsEM, negative-stain electron microscopy, Antibody, CSP, circumsporozoite protein, Plasmodium falciparum, malaria, Antigens, Protozoan, Enzyme-Linked Immunosorbent Assay, Calorimetry, Biology, Immunoglobulin light chain, Article, 03 medical and health sciences, CDR, complementarity-determining region, Malaria Vaccines, parasitic diseases, Animals, sporozoite, Pf, Plasmodium falciparum, mAb, monoclonal antibody, Molecular Biology, Gene, 030304 developmental biology, SPZ, sporozoite, biology.organism_classification, Mice, Inbred C57BL, NANP repeats, rsCSP, recombinant, shortened circumsporozoite protein, Antibody Formation, biology.protein, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de99becc742a1d2b18535c7f9a4637b1
https://doi.org/10.1016/j.jmb.2019.12.029

المؤلفون: Kassoum Kayentao, Joseph R. Francica, Carolina Barillas-Mury, Aissata Ongoiba, Rachel Vistein, T. Pholcharee, Photini Sinnis, Shanping Li, Safiatou Doumbo, Hyeseon Cho, Boubacar Traore, Barbara J. Flynn, Peter D. Crompton, Ming Zhao, Alison Roth, Lawrence Wang, Robert A. Seder, Mary E. Peterson, Lisa R. Olano, Lais Pereira, David Oyen, Azza H. Idris, Marlon Dillon, Ian A. Wilson, Patricia J. Lee, Samantha O. Aylor, Alvaro Molina-Cruz, Jeff Skinner, Sachie Kanatani, Arne Schön, Didier Doumtabe, Joshua Tan

المصدر: Science translational medicine

مصطلحات موضوعية: Plasmodium falciparum, Protozoan Proteins, Antibodies, Protozoan, Target peptide, Article, Epitope, Mice, Immunity, parasitic diseases, medicine, Animals, Humans, biology, General Medicine, biology.organism_classification, medicine.disease, Isotype, Virology, Immunoglobulin A, Malaria, Circumsporozoite protein, Sporozoites, biology.protein, Antibody

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8556a9825d193b988d58bba913deb13b
https://doi.org/10.1126/scitranslmed.abg2344

المؤلفون: Špela Binter, Daniel Emerling, Yevel Flores-Garcia, Sini Reponen, Andrew B. Ward, C. Richter King, Rachael S. Wash, Sean M. Carroll, Paul Kellam, Phillip C. Aoto, Jonathan L. Torres, David Oyen, Fidel Zavala, Allan Bradley, Emily Locke, Franck Lemiale, Ian A. Wilson, Qi Liang, T. Pholcharee

المساهمون: Torres, Jonathan L [0000-0003-0137-8497], Aoto, Phillip C [0000-0001-6518-0899], Binter, Špela [0000-0003-2335-6336], Pholcharee, Tossapol [0000-0002-5347-1936], Locke, Emily [0000-0003-1944-8473], Bradley, Allan [0000-0002-2349-8839], Kellam, Paul [0000-0003-3166-4734], Ward, Andrew B [0000-0001-7153-3769], Wilson, Ian A [0000-0002-6469-2419], Apollo - University of Cambridge Repository

المصدر: PLoS Pathogens
PLoS Pathogens, Vol 16, Iss 3, p e1008373 (2020)

مصطلحات موضوعية: Male, Plasmodium, Physiology, Protozoan Proteins, Antibodies, Protozoan, Molecular Dynamics, Biochemistry, Physical Chemistry, Epitope, law.invention, Binding Analysis, Antibodies, Monoclonal, Murine-Derived, Epitopes, Mice, Computational Chemistry, law, 1108 Medical Microbiology, Immune Physiology, Medicine and Health Sciences, IMPLEMENTATION, Biology (General), Enzyme-Linked Immunoassays, 0303 health sciences, Immune System Proteins, Crystallography, biology, Physics, 030302 biochemistry & molecular biology, Condensed Matter Physics, 3. Good health, Circumsporozoite protein, Chemistry, Sporozoites, 1107 Immunology, Physical Sciences, Recombinant DNA, Crystal Structure, Female, Antibody, Life Sciences & Biomedicine, Research Article, 0605 Microbiology, medicine.drug_class, QH301-705.5, Immunology, ANTIGEN, Plasmodium falciparum, Mice, Transgenic, Monoclonal antibody, Research and Analysis Methods, Microbiology, Antibodies, 03 medical and health sciences, Structure-Activity Relationship, Antigen, Virology, Parasite Groups, Genetics, medicine, Solid State Physics, Animals, Binding site, Immunoassays, Molecular Biology, Chemical Characterization, 030304 developmental biology, Science & Technology, Chemical Bonding, MALARIA INFECTION, Biology and Life Sciences, Proteins, Hydrogen Bonding, RC581-607, biology.organism_classification, Molecular biology, biology.protein, Immunologic Techniques, Parasitology, Binding Sites, Antibody, Immunologic diseases. Allergy, Apicomplexa

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45c6d0fca680bc5b7a215b61e2d3b555
http://hdl.handle.net/10044/1/81513

المؤلفون: Nicholas C. Wu, Jean-Philippe Julien, Elaine Thai, Katherine Prieto, Giulia Costa, Yevel Flores-Garcia, David Oyen, Ian A. Wilson, A. Bosch, Elena A. Levashina, Rajagopal Murugan, T. Pholcharee, Anna Weyrich, Hedda Wardemann, Angelo Valleriani, S.W. Scally

المصدر: The Journal of Experimental Medicine
Journal of Experimental Medicine

مصطلحات موضوعية: 0301 basic medicine, Protein Conformation, alpha-Helical, Glycan, Immunogen, medicine.drug_class, 030106 microbiology, Immunology, Plasmodium falciparum, Antibody Affinity, Protozoan Proteins, Antibodies, Protozoan, Monoclonal antibody, Epitope, Article, Infectious Disease and Host Defense, 03 medical and health sciences, Epitopes, 0302 clinical medicine, Antigen, Protein Domains, parasitic diseases, Anopheles, Malaria Vaccines, medicine, Immunology and Allergy, Animals, Malaria, Falciparum, 030304 developmental biology, 0303 health sciences, biology, Antibodies, Monoclonal, biology.organism_classification, Virology, In vitro, 3. Good health, Circumsporozoite protein, 030104 developmental biology, Sporozoites, biology.protein, Female, Antibody, 030217 neurology & neurosurgery

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccc0c8844a4d35eb476f3cd9d21e5c2e
https://pubmed.ncbi.nlm.nih.gov/32790871

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المؤلفون: Sue Sim, Anne E. McBride, Xiang Li, Heike Krebber, Selena Lorrey, Olivia Mackenzie, Chaiyaboot Ariyachet, T. Pholcharee, Christian Beißel, Patrick M. Martin, Katharine O'Brien

المصدر: Molecular Microbiology

مصطلحات موضوعية: 0301 basic medicine, Hyphal growth, Cytoplasm, Hyphae, Hyphal tip, Microbiology, Ribosome, Article, Fungal Proteins, 03 medical and health sciences, Candida albicans, MRNA transport, RNA, Messenger, Phosphorylation, Molecular Biology, biology, fungi, Spitzenkörper, RNA-Binding Proteins, RNA, biology.organism_classification, Cell biology, 030104 developmental biology, Protein Processing, Post-Translational, Gene Deletion

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efb62752256ca82760653616986d746f

المؤلفون: T. Pholcharee, Chih-Wei Lin, Nicholas C. Wu, Chung-Yi Wu, Andrew B. Ward, Yasunori Watanabe, Julianna Han, Sonu Kumar, Chang-Chun D Lee, Ian A. Wilson, Gemma E. Seabright, Ji-Rong Yang, Ming-Tsan Liu, Joel D. Allen, Max Crispin

المصدر: PLoS Pathogens, Vol 17, Iss 3, p e1009407 (2021)
PLoS Pathogens

مصطلحات موضوعية: RNA viruses, Influenza Viruses, Glycosylation, Physiology, Glycobiology, HIV Infections, Hemagglutinin Glycoproteins, Influenza Virus, Pathology and Laboratory Medicine, Antibodies, Viral, Biochemistry, Epitope, 0302 clinical medicine, Immunodeficiency Viruses, Immune Physiology, Medicine and Health Sciences, Post-Translational Modification, Biology (General), Neutralizing antibody, 0303 health sciences, education.field_of_study, Immune System Proteins, biology, Organic Compounds, virus diseases, Recombinant Proteins, Chemistry, Medical Microbiology, Viral Pathogens, Viral evolution, Viruses, Physical Sciences, Pathogens, Research Article, Glycan, QH301-705.5, Immunology, Population, Carbohydrates, Hemagglutinin (influenza), Cross Reactions, Microbiology, Antibodies, Viral Evolution, Virus, 03 medical and health sciences, Viral envelope, Virology, Retroviruses, Influenza, Human, Genetics, Humans, education, Microbial Pathogens, Molecular Biology, 030304 developmental biology, Evolutionary Biology, Influenza A Virus, H3N2 Subtype, Lentivirus, Organic Chemistry, Organisms, Chemical Compounds, Biology and Life Sciences, Proteins, HIV, RC581-607, Organismal Evolution, carbohydrates (lipids), Microbial Evolution, HIV-1, biology.protein, Parasitology, Immunologic diseases. Allergy, Mannose, Broadly Neutralizing Antibodies, 030217 neurology & neurosurgery, Orthomyxoviruses

وصف الملف: text

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb2916d37ccb87427a3956f2412b70d7
https://doi.org/10.1371/journal.ppat.1009407