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المؤلفون: Jacqueline S. L. Kloth, Ron H.J. Mathijssen, Henk-Jan Guchelaar, Stefan Sleijfer, T. van der Straaten, Neeltje Steeghs, Jesse J. Swen, Michiel C. Verboom, Anna K.L. Reyners, Hans Gelderblom
المساهمون: Guided Treatment in Optimal Selected Cancer Patients (GUTS), Targeted Gynaecologic Oncology (TARGON), Medical Oncology
المصدر: Pharmacogenomics Journal
Pharmacogenomics journal, 18(1), 49-55. Nature Publishing Group
Pharmacogenomics Journal, 18(1), 49-55
Pharmacogenomics Journal, 18(1), 49-55. Nature Publishing Groupمصطلحات موضوعية: 0301 basic medicine, Oncology, Male, PHARMACOKINETICS, medicine.medical_specialty, Gastrointestinal Stromal Tumors, MULTICENTER, Single-nucleotide polymorphism, Antineoplastic Agents, Biology, IMATINIB, Polymorphism, Single Nucleotide, 03 medical and health sciences, 0302 clinical medicine, RENAL-CELL CARCINOMA, Renal cell carcinoma, Internal medicine, Genotype, Genetics, medicine, Biomarkers, Tumor, Sunitinib, Humans, Gastrointestinal Neoplasms, Pharmacology, HYPERTENSION, GiST, Hazard ratio, Haplotype, Imatinib, ASSOCIATION, Middle Aged, EFFICACY, medicine.disease, VEGF, Progression-Free Survival, 1ST-LINE SUNITINIB, 030104 developmental biology, 030220 oncology & carcinogenesis, SINGLE NUCLEOTIDE POLYMORPHISMS, Cancer research, Molecular Medicine, Female, medicine.drug
وصف الملف: application/pdf
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المؤلفون: Dirk Jan A.R. Moes, Akin Inderson, Henk-Jan Guchelaar, J. den Hartigh, T. van der Straaten, S. A. S van der Bent, Hein W. Verspaget, Jesse J. Swen, Erik Olofsen, B. van Hoek
المساهمون: VU University medical center, Dermatology, AII - Inflammatory diseases
المصدر: European Journal of Clinical Pharmacology
European Journal of Clinical Pharmacology, 72(2), 163-74. Springer Verlag
European Journal of Clinical Pharmacology, 72(2), 163-174
Moes, D J A R, van der Bent, S A S, Swen, J J, van der Straaten, T, Inderson, A, Olofsen, E, Verspaget, H W, Guchelaar, H J, den Hartigh, J & van Hoek, B 2016, ' Population pharmacokinetics and pharmacogenetics of once daily tacrolimus formulation in stable liver transplant recipients ', European Journal of Clinical Pharmacology, vol. 72, no. 2, pp. 163-74 . https://doi.org/10.1007/s00228-015-1963-3مصطلحات موضوعية: Once daily tacrolimus, Adult, Male, Genotype, medicine.medical_treatment, Pharmacology, Liver transplantation, 030226 pharmacology & pharmacy, Models, Biological, Drug Administration Schedule, Tacrolimus, 03 medical and health sciences, 0302 clinical medicine, Pharmacokinetics, medicine, Cytochrome P-450 CYP3A, Humans, Pharmacology (medical), Population pharmacokinetics, CYP3A5, Aged, CYP3A4, business.industry, Advagraf, General Medicine, Middle Aged, Tissue Donors, Clinical trial, Immunosuppressive drug, surgical procedures, operative, Pharmacogenetics, 030220 oncology & carcinogenesis, Female, business, Immunosuppressive Agents
وصف الملف: application/pdf
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المؤلفون: Frans L. Opdam, E. Maartense, J Hartigh den, T. van der Straaten, C.J.H. van de Velde, H-J Guchelaar, Patrick Neven, Carolien H. Smorenburg, Hein Putter, Anne-Sophie Dieudonné, J.W.R. Nortier, Vincent O. Dezentjé, Hans Gelderblom, R. Vree
المصدر: Breast Cancer Research and Treatment
Breast Cancer Research and Treatment, 153(3), 583-590مصطلحات موضوعية: Oncology, Cancer Research, Pharmacology, Endoxifen, PHASE-I TRIAL, Risk Factors, Genotype, Medicine, Prospective Studies, Prospective cohort study, skin and connective tissue diseases, education.field_of_study, OUTCOMES, CYP2D6, Early breast cancer, Middle Aged, Clinical Trial, Phenotype, Treatment Outcome, Cytochrome P-450 CYP2D6, Toxicity, Female, BREAST-CANCER PATIENTS, Drug Monitoring, Life Sciences & Biomedicine, ACTIVITY SCORE, METABOLITE CONCENTRATIONS, medicine.drug, Adult, medicine.medical_specialty, Antineoplastic Agents, Hormonal, Population, Breast Neoplasms, digestive system, CISPLATIN, Breast cancer, Internal medicine, Humans, education, COMBINATION, POLYMORPHISMS, Aged, Science & Technology, business.industry, medicine.disease, EFFICACY, Tamoxifen, Pharmacogenetics, CELLS, business
وصف الملف: Print-Electronic
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المصدر: Journal of Thrombosis and Haemostasis. 11:1850-1854
مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Pediatrics, Adolescent, Physiology, Enzyme-Linked Immunosorbent Assay, Young Adult, Internal medicine, Coagulation testing, medicine, Humans, Young adult, Child, Hemostasis, Hematology, business.industry, Age Factors, Infant, Newborn, Infant, Age specific, Blood Coagulation Factors, Clinical research, Coagulation, Child, Preschool, Female, Developmental hemostasis, business
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المؤلفون: Henk-Jan Guchelaar, S. A. S van der Bent, T. van der Straaten, Jesse J. Swen, Akin Inderson, J. den Hartigh, B. van Hoek, Hein W. Verspaget, D J A R Moes, Erik Olofsen
المساهمون: VU University medical center, Dermatology
المصدر: European Journal of Clinical Pharmacology, 72(6), 775-6. Springer Verlag
European Journal of Clinical Pharmacology, 72(6), 775-776
European Journal of Clinical Pharmacology
Moes, D J A R, Swen, J J, van der Bent, S A S, van der Straaten, T, Inderson, A, Olofsen, E, Verspaget, H W, Guchelaar, H J, den Hartigh, J & van Hoek, B 2016, ' Response : Limited sampling strategies for once daily tacrolimus exposure monitoring ', European Journal of Clinical Pharmacology, vol. 72, no. 6, pp. 775-6 . https://doi.org/10.1007/s00228-016-2036-yمصطلحات موضوعية: medicine.medical_specialty, medicine.medical_treatment, Pharmacology toxicology, Liver transplantation, 030226 pharmacology & pharmacy, 01 natural sciences, Models, Biological, Tacrolimus, 03 medical and health sciences, 0302 clinical medicine, medicine, Limited sampling, Humans, Pharmacology (medical), Intensive care medicine, Kidney transplantation, Pharmacology, Blood Specimen Collection, business.industry, 010401 analytical chemistry, General Medicine, medicine.disease, Kidney Transplantation, 0104 chemical sciences, Liver Transplantation, Once daily, Drug Monitoring, business, Immunosuppressive Agents
وصف الملف: application/pdf
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المؤلفون: T. van der Straaten, P.A. von dem Borne, Judith A.M. Wessels, H-J Guchelaar, M.H. ten Brink, J. den Hartigh, Juliette Zwaveling
المصدر: Bone Marrow Transplantation, 47(2), 190-195
مصطلحات موضوعية: Adult, Transplantation Conditioning, Pharmacology, Biology, Isozyme, chemistry.chemical_compound, GSTP1, Pharmacokinetics, Humans, BU, Allele, Busulfan, Gene, Aged, Glutathione Transferase, pharmacogenetics, Transplantation, Polymorphism, Genetic, Hematopoietic Stem Cell Transplantation, hematopoietic SCT, Hematology, Glutathione, Middle Aged, Isoenzymes, Haematopoiesis, Treatment Outcome, chemistry, Toxicity, pharmacokinetics
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المؤلفون: Hans de Fijter, Bart A. Ploeger, Meindert Danhof, T. van der Straaten, Henk-Jan Guchelaar, Hans van Pelt, Jan den Hartigh, Rogier R. Press
المصدر: European Journal of Clinical Pharmacology, 66(6), 579-590
European Journal of Clinical Pharmacologyمصطلحات موضوعية: Adult, Male, Receptors, Steroid, ATP Binding Cassette Transporter, Subfamily B, Genotype, Prednisolone, Ciclosporin A Therapeutic drug monitoring Population pharmacokinetics Pharmacogenetics pregnane-x-receptor calcineurin inhibitors intravenous methylprednisolone clinical pharmacokinetics immunosuppressive drugs renal-transplantation genetic polymorphisms organ-transplantation oral bioavailability abcb1 polymorphisms, Physiology, Therapeutic drug monitoring, Biology, Drug Administration Schedule, Pharmacokinetics, Fluorescence Polarization Immunoassay, medicine, Cytochrome P-450 CYP3A, Humans, Pharmacology (medical), Population pharmacokinetics, ATP Binding Cassette Transporter, Subfamily B, Member 1, Genetic variability, Kidney transplantation, Survival analysis, Aged, Pharmacology, Polymorphism, Genetic, medicine.diagnostic_test, Body Weight, Pregnane X Receptor, General Medicine, Middle Aged, Ciclosporin, medicine.disease, Kidney Transplantation, Survival Analysis, Pharmacogenetics, Immunology, Cyclosporine, Female, Ciclosporin A, Immunosuppressive Agents, medicine.drug
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المؤلفون: K. van der Weide, T. van der Straaten, Kirsten M. Pondman, Jan P.A.M. Bogers, Jan N. M. Commandeur, J. van der Weide, Harriet M. Loovers, Dan Cohen, Ellen Langemeijer
المساهمون: AIMMS, Molecular and Computational Toxicology
المصدر: Pharmacogenomics Journal, 17(5), 471-478
Pharmacogenomics Journal. Nature Publishing Group
Van der Weide, K, Loovers, H, Pondman, K, Bogers, J, van der Straaten, T, Langemeijer, E V, Cohen, D, Commandeur, J N M & van der Weide, J 2016, ' Genetic risk factors for clozapine-induced neutropenia and agranulocytosis in a Dutch psychiatric population. ', Pharmacogenomics Journal . https://doi.org/10.1038/tpj.2016.32مصطلحات موضوعية: 0301 basic medicine, Adult, Male, medicine.medical_specialty, ATP Binding Cassette Transporter, Subfamily B, Neutropenia, Genotype, Pharmacogenomic Variants, Population, Genomics, 03 medical and health sciences, 0302 clinical medicine, Risk Factors, hemic and lymphatic diseases, Genetics, medicine, Humans, Genetic risk, Quinone Reductases, Psychiatry, education, Clozapine, Netherlands, Retrospective Studies, Pharmacology, education.field_of_study, business.industry, Mental Disorders, Middle Aged, medicine.disease, 030104 developmental biology, Drug development, 030220 oncology & carcinogenesis, Case-Control Studies, Molecular Medicine, Female, business, Functional genomics, medicine.drug, Agranulocytosis, Antipsychotic Agents
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مصطلحات موضوعية: Pharmacology, Candidate gene, Genetic variants, Genetic Variation, High-Throughput Nucleotide Sequencing, Cancer, Antineoplastic Agents, Genomics, Biology, Bioinformatics, medicine.disease, DNA sequencing, Cancer treatment, Drug treatment, Phenotype, Pharmacogenetics, Neoplasms, medicine, Humans, Pharmacology (medical), health care economics and organizations, Genome-Wide Association Study
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ec8173d1fe1495a8bc9642692df2f72
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المؤلفون: J A Romijn, A.G. Uitterlinden, A. Hofman, Nico Lakenberg, T. van der Straaten, Rob G H H Nelissen, Nienke R. Biermasz, Marian Beekman, Ingrid Meulenbelt, Margreet Kloppenburg, Herman M. Kroon, P.E. Slagboom, J. Bijsterbosch, J.B. van Meurs, Kim M J A Claessen, Alberto M. Pereira, B.J. Duijnisveld
المساهمون: Epidemiology, Internal Medicine, Amsterdam Gastroenterology Endocrinology Metabolism, General Internal Medicine
المصدر: Annals of the Rheumatic Diseases, 73(2), 433-436. BMJ Publishing Group
Annals of the rheumatic diseases, 73(2), 433-436. BMJ Publishing Group
Annals of the Rheumatic Diseases, 73(2), 433-436مصطلحات موضوعية: Male, Oncology, medicine.medical_specialty, Pathology, Immunology, Arthritis, Single-nucleotide polymorphism, Growth hormone receptor, Polymorphism, Single Nucleotide, Osteoarthritis, Hip, General Biochemistry, Genetics and Molecular Biology, Exon, Sex Factors, Rheumatology, Internal medicine, Osteoarthritis, Genotype, medicine, Humans, Immunology and Allergy, Genetic Predisposition to Disease, Allele, Genetic Association Studies, Aged, business.industry, Exons, Receptors, Somatotropin, Middle Aged, medicine.disease, Case-Control Studies, Female, Gene polymorphism, business, Body mass index, Gene Deletion, hormones, hormone substitutes, and hormone antagonists
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