المؤلفون: Kawai, Akira^Aff1, Naka, Norifumi, Shimomura, Akihiko^{Aff3, Aff4}, Takahashi, Shunji, Kitano, Shigehisa^{Aff6, Aff7, Aff8}, Imura, Yoshinori, Yonemori, Kan, Nakatani, Fumihiko, Iwata, Shintaro, Kobayashi, Eisuke, Outani, Hidetatsu, Tamiya, Hironari, Naito, Yoichi, Yamamoto, Noboru, Doi, Toshihiko

المصدر: Investigational New Drugs: Novel Anti-Cancer Therapeutics and Therapies. 39(6):1559-1567

المؤلفون: Naohiro Yasuda, Satoshi Takenaka, Sho Nakai, Takaaki Nakai, Shutaro Yamada, Yoshinori Imura, Hidetatsu Outani, Kenichiro Hamada, Hideki Yoshikawa, Norifumi Naka

المصدر: FEBS Open Bio, Vol 10, Iss 5, Pp 767-779 (2020)

مصطلحات موضوعية: LM8, lung metastasis, molecular targeted therapy, osteosarcoma, TAS‐115, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2211-5463

URL الوصول: https://doaj.org/article/5cbf079bfe7f41048f35778ed30cb849

المؤلفون: Shutaro Yamada, Yoshinori Imura, Takaaki Nakai, Sho Nakai, Naohiro Yasuda, Keiko Kaneko, Hidetatsu Outani, Satoshi Takenaka, Kenichiro Hamada, Akira Myoui, Nobuhito Araki, Takafumi Ueda, Kazuyuki Itoh, Hideki Yoshikawa, Norifumi Naka

المصدر: BMC Cancer, Vol 17, Iss 1, Pp 1-14 (2017)

مصطلحات موضوعية: TAS-115, Synovial sarcoma, C-MET, PDGFRα, Molecular targeted therapy, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: http://link.springer.com/article/10.1186/s12885-017-3324-3; https://doaj.org/toc/1471-2407

URL الوصول: https://doaj.org/article/0a9f7289c3704ad280f60fd471aef4c1

المؤلفون: Sho Nakai, Naohiro Yasuda, Satoshi Takenaka, Norifumi Naka, Takaaki Nakai, Yoshinori Imura, Shutaro Yamada, Hidetatsu Outani, Hideki Yoshikawa, Kenichiro Hamada

المصدر: FEBS Open Bio, Vol 10, Iss 5, Pp 767-779 (2020)
FEBS Open Bio

مصطلحات موضوعية: 0301 basic medicine, Lung Neoplasms, Receptor, Platelet-Derived Growth Factor alpha, Lung metastasis, TAS‐115, Mice, 0302 clinical medicine, Cell Movement, Medicine, Phosphorylation, lcsh:QH301-705.5, Research Articles, Mice, Inbred C3H, lung metastasis, Thiourea, Proto-Oncogene Proteins c-met, 030220 oncology & carcinogenesis, Quinolines, Osteosarcoma, Female, Signal transduction, Signal Transduction, Research Article, musculoskeletal diseases, molecular targeted therapy, Alpha (ethology), Bone Neoplasms, LM8, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Growth factor receptor, Cell Line, Tumor, Proto-Oncogene Proteins, osteosarcoma, Animals, Humans, Protein Kinase Inhibitors, Survival rate, neoplasms, Cell Proliferation, business.industry, Receptor Protein-Tyrosine Kinases, medicine.disease, Axl Receptor Tyrosine Kinase, 030104 developmental biology, fms-Like Tyrosine Kinase 3, lcsh:Biology (General), Cell culture, Cancer research, business, Proto-Oncogene Proteins c-akt

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::548bc243ed6f247c04371d9e23931e01
https://doaj.org/article/5cbf079bfe7f41048f35778ed30cb849

المؤلفون: Shintaro Iwata, Eisuke Kobayashi, Shigehisa Kitano, Kan Yonemori, Hironari Tamiya, Hidetatsu Outani, Noboru Yamamoto, Fumihiko Nakatani, Toshihiko Doi, Yoichi Naito, Shunji Takahashi, Akihiko Shimomura, Yoshinori Imura, Norifumi Naka, Akira Kawai

المصدر: Investigational New Drugs

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, medicine.medical_specialty, Adolescent, Maximum Tolerated Dose, medicine.drug_class, Met proto-oncogene, Antineoplastic Agents, TAS-115, Disease, Gastroenterology, Tyrosine-kinase inhibitor, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Stable Disease, Refractory, Phase I Studies, Internal medicine, Biomarkers, Tumor, medicine, Humans, Pharmacology (medical), Protein Kinase Inhibitors, Pharmacology, Osteosarcoma, Dose-Response Relationship, Drug, Kinase, business.industry, Thiourea, McDonough feline sarcoma, Multi-kinase inhibitor, Middle Aged, medicine.disease, Survival Analysis, Vascular endothelial growth factor receptor, 030104 developmental biology, Oncology, Tolerability, 030220 oncology & carcinogenesis, Cohort, Quinolines, Female, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfb8597a5b27607d44a4596e44d9ae9a
https://doi.org/10.21203/rs.3.rs-346457/v1

المؤلفون: Akira Kawai, Toshihiko Doi, Norifumi Naka, Hiroji Uemura, Noboru Yamamoto, Nobuaki Matsubara, Shunji Takahashi

المصدر: Investigational New Drugs

مصطلحات موضوعية: 0301 basic medicine, Male, Vascular Endothelial Growth Factor A, Gastroenterology, 0302 clinical medicine, Leukocytopenia, Neoplasms, Phase I Studies, Solid tumors, Pharmacology (medical), Aged, 80 and over, Thiourea, Middle Aged, Proto-Oncogene Proteins c-met, Rash, Oncology, Tolerability, 030220 oncology & carcinogenesis, Quinolines, MET, Female, medicine.symptom, Adult, medicine.medical_specialty, Adolescent, Maximum Tolerated Dose, PDGFR, Anemia, Antineoplastic Agents, TAS-115, Phase 1, Neutropenia, Drug Administration Schedule, 03 medical and health sciences, Young Adult, VEGFR, Pharmacokinetics, Internal medicine, medicine, Humans, Adverse effect, Protein Kinase Inhibitors, Aged, Pharmacology, business.industry, FMS, Multi-kinase inhibitor, medicine.disease, Vascular Endothelial Growth Factor Receptor-2, 030104 developmental biology, Pharmacodynamics, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06921ec33682fa46ca26a05edf2c91d1
https://pubmed.ncbi.nlm.nih.gov/31820255

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المؤلفون: Keiko Kaneko, Satoshi Takenaka, Norifumi Naka, Nobuhito Araki, Shutaro Yamada, Hidetatsu Outani, Takaaki Nakai, Sho Nakai, Takafumi Ueda, Kazuyuki Itoh, Kenichiro Hamada, Hideki Yoshikawa, Naohiro Yasuda, Yoshinori Imura, Akira Myoui

المصدر: BMC Cancer
BMC Cancer, Vol 17, Iss 1, Pp 1-14 (2017)

مصطلحات موضوعية: Male, 0301 basic medicine, PDGFRα, Cancer Research, Receptor, Platelet-Derived Growth Factor alpha, Angiogenesis Inhibitors, Tyrosine-kinase inhibitor, Receptor tyrosine kinase, Mice, chemistry.chemical_compound, 0302 clinical medicine, Molecular targeted therapy, Phosphorylation, Mice, Inbred BALB C, Sulfonamides, biology, Autophosphorylation, Thiourea, Proto-Oncogene Proteins c-met, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Oncology, 030220 oncology & carcinogenesis, Quinolines, Tyrosine kinase, Research Article, Signal Transduction, Indazoles, C-Met, medicine.drug_class, Mice, Nude, TAS-115, lcsh:RC254-282, Synovial sarcoma, Sarcoma, Synovial, 03 medical and health sciences, Growth factor receptor, Cell Line, Tumor, Genetics, medicine, Animals, Humans, Protein kinase A, Protein Kinase Inhibitors, Protein kinase B, business.industry, Xenograft Model Antitumor Assays, Pyrimidines, 030104 developmental biology, chemistry, biology.protein, Cancer research, C-MET, Phosphatidylinositol 3-Kinase, business, Proto-Oncogene Proteins c-akt

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64b3ed340e66fe11772965ed36c36592
https://doi.org/10.1186/s12885-017-3324-3

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