المؤلفون: Stefan Christen, Doriane Lorendeau, Roberta Schmieder, Dorien Broekaert, Kristine Metzger, Koen Veys, Ilaria Elia, Joerg Martin Buescher, Martin Franz Orth, Shawn Michael Davidson, Thomas Georg Philipp Grünewald, Katrien De Bock, Sarah-Maria Fendt

المصدر: Cell Reports, Vol 17, Iss 3, Pp 837-848 (2016)

مصطلحات موضوعية: pyruvate carboxylase, mitochondrial pyruvate concentration, lung metastasis, breast cancer, TCA cycle anaplerosis, microenvironment, glycolytic metabolism, cancer metabolism, 13C tracer analysis, pyruvate metabolism, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124716312815; https://doaj.org/toc/2211-1247

URL الوصول: https://doaj.org/article/5ab2f0b51c034757927446c1f559236f

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المؤلفون: Koen Veys, Thomas G. P. Grunewald, Kristine Metzger, Sarah-Maria Fendt, Ilaria Elia, Dorien Broekaert, Doriane Lorendeau, Martin F. Orth, Shawn M. Davidson, Joerg Martin Buescher, Katrien De Bock, Roberta Schmieder, Stefan Christen

المساهمون: Koch Institute for Integrative Cancer Research at MIT, Davidson, Shawn Michael

المصدر: Elsevier
Cell Reports, Vol 17, Iss 3, Pp 837-848 (2016)
Cell Reports, 17 (3)

مصطلحات موضوعية: 0301 basic medicine, Lung Neoplasms, Metabolite, cancer metabolism, chemistry.chemical_compound, Adenosine Triphosphate, Cytosol, Pyruvic Acid, Tumor Microenvironment, Citrate synthase, lcsh:QH301-705.5, chemistry.chemical_classification, Carbon Isotopes, biology, lung metastasis, Tricarboxylic acid, Pyruvate carboxylase, Mitochondria, pyruvate carboxylase, mitochondrial pyruvate concentration, breast cancer, TCA cycle anaplerosis, microenvironment, glycolytic metabolism, 13C tracer analysis, pyruvate metabolism, Adenosine Diphosphate, medicine.anatomical_structure, Biochemistry, Isotope Labeling, Female, Citric Acid Cycle, Breast Neoplasms, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Breast cancer, Acetyl Coenzyme A, Cell Line, Tumor, medicine, Humans, Enzyme kinetics, Pyruvate Carboxylase, Lung, medicine.disease, Cell Compartmentation, Glutamine, 030104 developmental biology, lcsh:Biology (General), chemistry, biology.protein

وصف الملف: Print; application/pdf; application/application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::460eaf62ed2d14714bf115ae73b27d71
https://pubmed.ncbi.nlm.nih.gov/27732858

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المؤلفون: Cluntun AA; Graduate Field of Biochemistry, Molecular & Cell Biology, Cornell University, Ithaca, NY, USA; King Abdullah International Medical Research Center (KAIMRC), Riyadh, Saudi Arabia., Lukey MJ; Department of Molecular Medicine, Cornell University, Ithaca, NY 14853, USA., Cerione RA; Department of Molecular Medicine, Cornell University, Ithaca, NY 14853, USA; Department of Chemistry and Chemical Biology, Cornell University, Ithaca NY 14853, USA., Locasale JW; Department of Pharmacology and Cancer Biology, Duke Cancer Institute, Duke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC, USA.

المصدر: Trends in cancer [Trends Cancer] 2017 Mar; Vol. 3 (3), pp. 169-180.

نوع المنشور: Journal Article; Review; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101665956 Publication Model: Print Cited Medium: Print ISSN: 2405-8033 (Print) Linking ISSN: 24058025 NLM ISO Abbreviation: Trends Cancer Subsets: MEDLINE

مواضيع طبية MeSH: Glutaminase/*metabolism , Glutamine/*metabolism , Neoplasms/*metabolism, Glutaminase/genetics ; Humans ; Molecular Targeted Therapy ; Neoplasms/pathology ; Neoplasms/therapy