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المؤلفون: Zhongzheng Zhu, Huangbin Lu, Hua Yu, Song Gao, Wei Dong, Jianguo Wu, Wen-Ming Cong, Xuejun Chen, Xianling Guo, Hui Dong, Qing Xu, Juemin Fang
المصدر: Translational Oncology
Translational Oncology, Vol 14, Iss 10, Pp 101168-(2021)مصطلحات موضوعية: musculoskeletal diseases, Cancer Research, congenital, hereditary, and neonatal diseases and abnormalities, Genomic profiling, Biology, BWA, Burrows-Wheeler Aligner, medicine.disease_cause, Target therapy, TKI, tyrosine kinase inhibitor, Pathogenesis, GA, genomic aberration, HBsAb, anti-hepatitis B surface antibody, HBeAb, anti-hepatitis B virus e antibody, medicine, FISH, fluorescent in situ hybridization, RC254-282, Intrahepatic Cholangiocarcinoma, Original Research, Intrahepatic cholangiocarcinoma, Mutation, ICC, intrahepatic cholangiocarcinoma, integumentary system, Gene rearrangement, SNV, single nucleotide variant, Genomic aberration, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, medicine.disease, TNM, tumor-node-metastasis, Phenotype, Fibroblast growth factor receptor, HBcAb, anti-hepatitis B virus core antibody, FFPE, formalin-fixed paraffin-embedded, NGS, next-generation sequencing, stomatognathic diseases, HBV, hepatitis B virus, HBsAg, hepatitis B surface antigen, Oncology, PD-L1, programmed cell death-ligand 1, STAR, spliced transcripts alignment to a reference, HCV, hepatitis C virus, TKD, tyrosine kinase domain, embryonic structures, Cancer research, FGFR, Fibroblast growth factor receptor, Hepatolithiasis, CD10, cluster of differentiation 10, IHC, immunohistochemistry
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المؤلفون: Letizia Foroni, Jane F. Apperley, Mary Alikian, Robert Peter Gale
المصدر: Biomolecular Detection and Quantification, Vol 11, Iss C, Pp 4-20 (2017)
Biomolecular Detection and Quantificationمصطلحات موضوعية: Oncology, Pathology, SCT, stem cell transplant, Review Article, Disease, Biochemistry, lcsh:Microbiology, CMR, complete molecular response/remission, ZMW, zero-mode wave-guided, 0302 clinical medicine, LSC, leukemic stem cell, EURO-SKI, European Stop Tyrosine Kinase Inhibitor Study, DESTINY, De-Escalation and Stopping Treatment of Imatinib, Nilotinib or sprYcel in Chronic Myeloid Leukaemia, NTC, No Template Control, PCR, Polymerase Chain Reaction, lcsh:QH301-705.5, ABL, RT, reverse transcription, CP, chronic phase, ALL, acute lymphoblastic leukaemia, CAP, College of American Pathology, KDa, Kilo Dalton, AP, accelerated phase, μg, microgram, RT-dPCR, reverse transcription-digital polymerase chain reaction, 030220 oncology & carcinogenesis, NGS, TKD, tyrosine kinase domain, ARQ, armored RNA Quant, IRIS, interferon and cytarabine versus STI571, medicine.medical_specialty, Cancer therapy, IS, International Scale, cDNA, coding or complimentary DNA, RT-qPCR, reverse transcription-quantitative polymerase chain reaction, Chronic myeloid leukaemia, 03 medical and health sciences, ELN, European Leukaemia Net, STIM, stop imatinib, Molecular Biology, CML, chronic myeloid leukaemia, LPC, leukemic progenitor cells, NGS, next generation sequencing, BMT, bone marrow transplantation, Q-PCR, quantitative polymerase chain reaction, respiratory tract diseases, IC, inhibotory concentration, MMR, major molecular response/remission, SMRT, single-molecule real-time sequencing, Mbp, mega base pair, dPCR, digital polymerase chain reaction, m-bcr, minor-breakpoint cluster region, dMIQE, Minimum Information for Publication of Quantitative Digital PCR Experiments, PFS, Progression Free Survival, lcsh:QR1-502, GUSB, glucuronidase beta gene, Kbp, Kilo Base Pairs, μ-bcr, micro-breakpoint cluster region, ABL1, Abelson murine leukaemia virus, MRD, minimal residual disease, TKI, tyrosine kinase inhibitor, DNA, deoxyribonucleic acid, Structural Biology, hemic and lymphatic diseases, CES, capillary electrophoresis sequencing, CML, μl, microliter, breakpoint cluster region, Myeloid leukemia, allo-SCT, Allogeneic Stem Cell Transplantation, LoQ, limit of quantification, mRNA, messenger RNA, medicine.anatomical_structure, MRD, emPCR, emulsion PCR, Molecular Medicine, Ph, Philadelpia, WHO, World Health Organisation, ATP, adenosine triphosphate, Bp, base pair, NCCN, National Comprehensive Cancer Network, QC, Quality Control, BC, blast crisis, LoD, limit of detection, PB, Peripheral Blood, gDNA, genomic deoxyribonucleic acid, Internal medicine, InDels, insertions and deletions, Molecular monitoring, medicine, EAC, Europe Against Cancer, nM, manomolar, business.industry, dPCR, MR, deep molecular response/remission, M-bcr, major-breakpoint cluster region, Gold standard (test), lcsh:Biology (General), NEQAS, National External Quality Assessement Service, BM, bone marrow, BCR, breakpoint cluster region, Bone marrow, business, 030215 immunology
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المؤلفون: Ravi Radhakrishnan, Yingting Liu, Jin H. Park, Mark A. Lemmon
المصدر: Biochemical Journal
مصطلحات موضوعية: erlotinib, Insecta, Protein Conformation, receptor tyrosine kinase (RTK), gefitinib, Crystallography, X-Ray, 01 natural sciences, Biochemistry, TKI, tyrosine kinase inhibitor, Receptor tyrosine kinase, FEP, free energy perturbation, RMSD, root mean square deviation, heterocyclic compounds, Epidermal growth factor receptor, Erlotinib Hydrochloride, 0303 health sciences, biology, epidermal growth factor receptor (EGFR), MD, molecular dynamics, 3. Good health, ErbB Receptors, inhibitor, TKD, tyrosine kinase domain, Erlotinib, Tyrosine kinase, medicine.drug, Proto-oncogene tyrosine-protein kinase Src, SASA, surface-accessible surface area, MM/PBSA, molecular mechanics/Poisson–Boltzmann surface area, Accelerated Publication, NSCLC, non-small-cell lung cancer, Cell Line, 03 medical and health sciences, Gefitinib, medicine, Animals, Humans, cancer, Molecular Biology, neoplasms, Protein Kinase Inhibitors, 030304 developmental biology, X-ray crystallography, DFG, Asp-Phe-Gly, 010405 organic chemistry, IFD, Induced Fit Docking, Cell Biology, molecular dynamics, 0104 chemical sciences, respiratory tract diseases, Protein Structure, Tertiary, EGFR, epidermal growth factor receptor, DTT, dithiothreitol, ROR1, biology.protein, Cancer research, Quinazolines
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e9d91577bc7eb408e8f5e1f0cc55130
https://pubmed.ncbi.nlm.nih.gov/23101586 -
4دورية أكاديمية
المؤلفون: Alikian M; Centre for Haematology, Department of Medicine, Imperial College London Hammersmith Hospital, London UK; Imperial Molecular Pathology, Imperial College Healthcare Trust, Hammersmith Hospital, London, UK., Gale RP; Centre for Haematology, Department of Medicine, Imperial College London Hammersmith Hospital, London UK., Apperley JF; Centre for Haematology, Department of Medicine, Imperial College London Hammersmith Hospital, London UK., Foroni L; Centre for Haematology, Department of Medicine, Imperial College London Hammersmith Hospital, London UK.
المصدر: Biomolecular detection and quantification [Biomol Detect Quantif] 2017 Feb 14; Vol. 11, pp. 4-20. Date of Electronic Publication: 2017 Feb 14 (Print Publication: 2017).
نوع المنشور: Journal Article; Review
بيانات الدورية: Publisher: Elsevier GmbH Country of Publication: Germany NLM ID: 101667177 Publication Model: eCollection Cited Medium: Print ISSN: 2214-7535 (Print) Linking ISSN: 22147535 NLM ISO Abbreviation: Biomol Detect Quantif Subsets: PubMed not MEDLINE