المؤلفون: Tsuchitani T; iHuman Institute, ShanghaiTech University, Shanghai, China.; Laboratory of Quantitative System Pharmacokinetics/Pharmacodynamics, School of Pharmacy, Josai International University (JIU), Tokyo, Japan., Tomaru A; Laboratory of Quantitative System Pharmacokinetics/Pharmacodynamics, School of Pharmacy, Josai International University (JIU), Tokyo, Japan., Aoki Y; Laboratory of Quantitative System Pharmacokinetics/Pharmacodynamics, School of Pharmacy, Josai International University (JIU), Tokyo, Japan.; Drug Metabolism and Pharmacokinetics, Research and Early Development, Cardiovascular, Renal and Metabolism (CVRM), BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Ishiguro N; Pharmacokinetics and Non-Clinical Safety Department, Nippon Boehringer Ingelheim Co., Ltd., Kobe, Hyogo, Japan., Tsuda Y; Clinical Pharmacology Department, Nippon Boehringer Ingelheim Co., Ltd., Kobe, Hyogo, Japan., Sugiyama Y; iHuman Institute, ShanghaiTech University, Shanghai, China.; Laboratory of Quantitative System Pharmacokinetics/Pharmacodynamics, School of Pharmacy, Josai International University (JIU), Tokyo, Japan.

المصدر: CPT: pharmacometrics & systems pharmacology [CPT Pharmacometrics Syst Pharmacol] 2024 Jul; Vol. 13 (7), pp. 1224-1237. Date of Electronic Publication: 2024 May 14.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley Country of Publication: United States NLM ID: 101580011 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2163-8306 (Electronic) Linking ISSN: 21638306 NLM ISO Abbreviation: CPT Pharmacometrics Syst Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Telmisartan*/pharmacokinetics , Telmisartan*/administration & dosage , Solute Carrier Organic Anion Transporter Family Member 1B3*/metabolism , Solute Carrier Organic Anion Transporter Family Member 1B3*/antagonists & inhibitors , Models, Biological* , Hepatocytes*/metabolism, Humans ; Angiotensin II Type 1 Receptor Blockers/pharmacokinetics ; Angiotensin II Type 1 Receptor Blockers/administration & dosage ; Angiotensin II Type 1 Receptor Blockers/pharmacology ; Liver/metabolism ; Nonlinear Dynamics ; Benzimidazoles/pharmacokinetics ; Benzimidazoles/administration & dosage ; Benzoates/pharmacokinetics ; Benzoates/administration & dosage ; Healthy Volunteers ; Administration, Oral

المؤلفون: Cardona P; Clinical Pharmacology, Modeling and Simulation, Amgen Inc., Thousand Oaks, CA, USA., Dutta S; Clinical Pharmacology, Modeling and Simulation, Amgen Inc., Thousand Oaks, CA, USA., Houk B; Clinical Pharmacology, Modeling and Simulation, Amgen Inc., Thousand Oaks, CA, USA.

المصدر: Clinical pharmacology in drug development [Clin Pharmacol Drug Dev] 2024 Jul; Vol. 13 (7), pp. 810-818. Date of Electronic Publication: 2024 Feb 29.

نوع المنشور: Journal Article; Clinical Trial, Phase I; Randomized Controlled Trial

بيانات الدورية: Publisher: Wiley Country of Publication: United States NLM ID: 101572899 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2160-7648 (Electronic) Linking ISSN: 2160763X NLM ISO Abbreviation: Clin Pharmacol Drug Dev Subsets: MEDLINE

مواضيع طبية MeSH: Liver-Specific Organic Anion Transporter 1*/antagonists & inhibitors , Liver-Specific Organic Anion Transporter 1*/metabolism , Solute Carrier Organic Anion Transporter Family Member 1B3*/antagonists & inhibitors , Solute Carrier Organic Anion Transporter Family Member 1B3*/metabolism , Cytochrome P-450 CYP3A Inhibitors*/pharmacology , Cytochrome P-450 CYP3A Inhibitors*/administration & dosage , Cytochrome P-450 CYP3A*/metabolism , Rifampin*/pharmacology , Rifampin*/administration & dosage , Drug Interactions* , Cytochrome P-450 CYP3A Inducers*/pharmacology, Humans ; Male ; Adult ; Female ; Young Adult ; Administration, Oral ; Middle Aged ; Healthy Volunteers ; Area Under Curve ; Itraconazole/pharmacology ; Itraconazole/administration & dosage ; Itraconazole/pharmacokinetics ; Spiro Compounds/pharmacokinetics ; Spiro Compounds/administration & dosage ; Spiro Compounds/pharmacology

المؤلفون: Bi YA; Pharmacokinetics, Dynamics, and Metabolism, Pfizer R&D, Pfizer Inc., Groton, Connecticut, USA., Jordan S; Pharmacokinetics, Dynamics, and Metabolism, Pfizer R&D, Pfizer Inc., Groton, Connecticut, USA., King-Ahmad A; Pharmacokinetics, Dynamics, and Metabolism, Pfizer R&D, Pfizer Inc., Groton, Connecticut, USA., West MA; Pharmacokinetics, Dynamics, and Metabolism, Pfizer R&D, Pfizer Inc., Groton, Connecticut, USA., Varma MVS; Pharmacokinetics, Dynamics, and Metabolism, Pfizer R&D, Pfizer Inc., Groton, Connecticut, USA.

المصدر: Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2024 Jun; Vol. 115 (6), pp. 1336-1345. Date of Electronic Publication: 2024 Feb 26.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wiley Country of Publication: United States NLM ID: 0372741 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-6535 (Electronic) Linking ISSN: 00099236 NLM ISO Abbreviation: Clin Pharmacol Ther Subsets: MEDLINE

مواضيع طبية MeSH: Liver-Specific Organic Anion Transporter 1*/metabolism , Liver-Specific Organic Anion Transporter 1*/antagonists & inhibitors , Drug Interactions* , Macaca fascicularis* , Cytochrome P-450 CYP2C8*/metabolism , Renal Insufficiency, Chronic*/metabolism , Hepatocytes*/metabolism , Hepatocytes*/drug effects , Rifampin*/pharmacology , Solute Carrier Organic Anion Transporter Family Member 1B3*/metabolism , Solute Carrier Organic Anion Transporter Family Member 1B3*/antagonists & inhibitors, Humans ; Animals ; Male ; Glycine/analogs & derivatives ; Glycine/pharmacokinetics ; Liver Diseases/metabolism ; Models, Biological ; HEK293 Cells ; Female ; Liver/metabolism ; Adult ; Cytochrome P-450 CYP2C8 Inhibitors/pharmacokinetics

المؤلفون: Gong M; School of Agriculture, Yangtze University, Jingzhou, 434025, China; Laboratory of Toxicant Analysis, Institute of Pharmacology and Toxicology, Academy of Military Medical Sciences, Beijing, 100850, China., Li Z; Laboratory of Toxicant Analysis, Institute of Pharmacology and Toxicology, Academy of Military Medical Sciences, Beijing, 100850, China., Xu H; Laboratory of Toxicant Analysis, Institute of Pharmacology and Toxicology, Academy of Military Medical Sciences, Beijing, 100850, China., Ma B; Laboratory of Toxicant Analysis, Institute of Pharmacology and Toxicology, Academy of Military Medical Sciences, Beijing, 100850, China., Gao P; Laboratory of Toxicant Analysis, Institute of Pharmacology and Toxicology, Academy of Military Medical Sciences, Beijing, 100850, China., Wang L; Laboratory of Toxicant Analysis, Institute of Pharmacology and Toxicology, Academy of Military Medical Sciences, Beijing, 100850, China., Li J; School of Agriculture, Yangtze University, Jingzhou, 434025, China., Wu Q; School of Agriculture, Yangtze University, Jingzhou, 434025, China. Electronic address: wql106@163.com., Wu J; Laboratory of Toxicant Analysis, Institute of Pharmacology and Toxicology, Academy of Military Medical Sciences, Beijing, 100850, China. Electronic address: ammswjf@hotmail.com., Xie J; Laboratory of Toxicant Analysis, Institute of Pharmacology and Toxicology, Academy of Military Medical Sciences, Beijing, 100850, China. Electronic address: xiejw@bmi.ac.cn.

المصدر: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association [Food Chem Toxicol] 2024 Jun; Vol. 188, pp. 114665. Date of Electronic Publication: 2024 Apr 17.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 8207483 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-6351 (Electronic) Linking ISSN: 02786915 NLM ISO Abbreviation: Food Chem Toxicol Subsets: MEDLINE

مواضيع طبية MeSH: Solute Carrier Organic Anion Transporter Family Member 1B3*/metabolism , Solute Carrier Organic Anion Transporter Family Member 1B3*/genetics , Amanitins*/toxicity, Humans ; HEK293 Cells ; Cell Line ; Cell Survival/drug effects ; Alpha-Amanitin/toxicity ; Hep G2 Cells

المؤلفون: Huang Y; Department of Chemistry, University of California, Santa Barbara, CA 93106-5080., Chen X; Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara, CA 93106-5080., Zhu Z; Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara, CA 93106-5080., Mukherjee A; Department of Chemistry, University of California, Santa Barbara, CA 93106-5080.; Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara, CA 93106-5080.; Department of Chemical Engineering, University of California, Santa Barbara, CA 93106-5080.

المصدر: Chembiochem : a European journal of chemical biology [Chembiochem] 2024 May 17; Vol. 25 (10), pp. e202400087. Date of Electronic Publication: 2024 May 02.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley-VCH Verlag Country of Publication: Germany NLM ID: 100937360 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1439-7633 (Electronic) Linking ISSN: 14394227 NLM ISO Abbreviation: Chembiochem Subsets: MEDLINE

مواضيع طبية MeSH: Water*/chemistry , Magnetic Resonance Imaging*/methods , Aquaporin 1*/metabolism , Aquaporin 1*/genetics , Genes, Reporter* , Solute Carrier Organic Anion Transporter Family Member 1B3*/metabolism , Solute Carrier Organic Anion Transporter Family Member 1B3*/genetics, Humans ; Gadolinium/chemistry ; Contrast Media/chemistry ; Contrast Media/metabolism ; HEK293 Cells ; Animals

المؤلفون: Bechtold BJ; Department of Pharmaceutical Sciences, Washington State University, 412 E. Spokane Falls Blvd., Spokane, Washington 99202, United States., Lynch KD; Department of Pharmaceutical Sciences, Washington State University, 412 E. Spokane Falls Blvd., Spokane, Washington 99202, United States., Oyanna VO; Department of Pharmaceutical Sciences, Washington State University, 412 E. Spokane Falls Blvd., Spokane, Washington 99202, United States., Call MR; Department of Pharmaceutical Sciences, Washington State University, 412 E. Spokane Falls Blvd., Spokane, Washington 99202, United States., Graf TN; Department of Chemistry and Biochemistry, University of North Carolina at Greensboro, Greensboro, North Carolina 27412, United States., Oberlies NH; Department of Chemistry and Biochemistry, University of North Carolina at Greensboro, Greensboro, North Carolina 27412, United States., Clarke JD; Department of Pharmaceutical Sciences, Washington State University, 412 E. Spokane Falls Blvd., Spokane, Washington 99202, United States.

المصدر: Molecular pharmaceutics [Mol Pharm] 2024 May 06; Vol. 21 (5), pp. 2284-2297. Date of Electronic Publication: 2024 Mar 26.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101197791 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1543-8392 (Electronic) Linking ISSN: 15438384 NLM ISO Abbreviation: Mol Pharm Subsets: MEDLINE

مواضيع طبية MeSH: Rifampin*/pharmacokinetics , Liver-Specific Organic Anion Transporter 1*/genetics , Liver-Specific Organic Anion Transporter 1*/metabolism , Mice, Transgenic* , Silymarin*/pharmacokinetics , Pravastatin*/pharmacokinetics , Pravastatin*/administration & dosage , Solute Carrier Organic Anion Transporter Family Member 1B3*/genetics , Solute Carrier Organic Anion Transporter Family Member 1B3*/metabolism , Drug Interactions*, Animals ; Mice ; Humans ; Quinolines/pharmacokinetics ; Coproporphyrins/metabolism ; Male ; Organic Anion Transporters/genetics ; Organic Anion Transporters/metabolism

المؤلفون: Buck SAJ; Department of Medical Oncology, Erasmus MC Cancer Institute, University Medical Centre Rotterdam, Rotterdam, The Netherlands., Talebi Z; Division of Pharmaceutics and Pharmacology, College of Pharmacy, The Ohio State University, Columbus, Ohio, USA., Drabison T; Division of Pharmaceutics and Pharmacology, College of Pharmacy, The Ohio State University, Columbus, Ohio, USA., Jin Y; Division of Pharmaceutics and Pharmacology, College of Pharmacy, The Ohio State University, Columbus, Ohio, USA., Gibson AA; Division of Pharmaceutics and Pharmacology, College of Pharmacy, The Ohio State University, Columbus, Ohio, USA., Hu P; Division of Outcomes and Translational Sciences, College of Pharmacy, The Ohio State University, Columbus, Ohio, USA., de Bruijn P; Department of Medical Oncology, Erasmus MC Cancer Institute, University Medical Centre Rotterdam, Rotterdam, The Netherlands., de Ridder CMA; Department of Urology, Erasmus MC Cancer Institute, University Medical Centre Rotterdam, Rotterdam, The Netherlands., Stuurman D; Department of Urology, Erasmus MC Cancer Institute, University Medical Centre Rotterdam, Rotterdam, The Netherlands., Hu S; Division of Outcomes and Translational Sciences, College of Pharmacy, The Ohio State University, Columbus, Ohio, USA., van Weerden WM; Department of Urology, Erasmus MC Cancer Institute, University Medical Centre Rotterdam, Rotterdam, The Netherlands., Koolen SLW; Department of Medical Oncology, Erasmus MC Cancer Institute, University Medical Centre Rotterdam, Rotterdam, The Netherlands., de Wit R; Department of Medical Oncology, Erasmus MC Cancer Institute, University Medical Centre Rotterdam, Rotterdam, The Netherlands., Sparreboom A; Division of Pharmaceutics and Pharmacology, College of Pharmacy, The Ohio State University, Columbus, Ohio, USA., Mathijssen RHJ; Department of Medical Oncology, Erasmus MC Cancer Institute, University Medical Centre Rotterdam, Rotterdam, The Netherlands., Eisenmann ED; Division of Pharmaceutics and Pharmacology, College of Pharmacy, The Ohio State University, Columbus, Ohio, USA.

المصدر: International journal of cancer [Int J Cancer] 2024 Jul 15; Vol. 155 (2), pp. 314-323. Date of Electronic Publication: 2024 Mar 16.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 0042124 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-0215 (Electronic) Linking ISSN: 00207136 NLM ISO Abbreviation: Int J Cancer Subsets: MEDLINE

مواضيع طبية MeSH: Docetaxel*/pharmacology , Docetaxel*/pharmacokinetics , Solute Carrier Organic Anion Transporter Family Member 1B3*/metabolism , Prostatic Neoplasms*/drug therapy , Prostatic Neoplasms*/metabolism , Prostatic Neoplasms*/pathology , Xenograft Model Antitumor Assays* , Pyrazoles*/pharmacology , Pyrazoles*/pharmacokinetics, Humans ; Male ; Animals ; Mice ; Drug Interactions ; Cell Line, Tumor ; HEK293 Cells

المؤلفون: Tan Y; Department of Hepatology, Hunan Children's Hospital, Changsha, Hunan 410007, China. lishuangjie40@163.com., Ouyang W, Jiang T, Tang L, Zhang H, Yu Y, Qin X, Li S

المصدر: Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics [Zhonghua Yi Xue Yi Chuan Xue Za Zhi] 2024 Jun 10; Vol. 41 (6), pp. 715-719.

نوع المنشور: Journal Article; English Abstract

بيانات الدورية: Publisher: Sichuan University Country of Publication: China NLM ID: 9425197 Publication Model: Print Cited Medium: Print ISSN: 1003-9406 (Print) Linking ISSN: 10039406 NLM ISO Abbreviation: Zhonghua Yi Xue Yi Chuan Xue Za Zhi Subsets: MEDLINE

مواضيع طبية MeSH: Solute Carrier Organic Anion Transporter Family Member 1B3*/genetics , Genetic Testing*/methods, Humans ; Male ; Female ; Child ; Child, Preschool ; Liver-Specific Organic Anion Transporter 1/genetics ; Exome Sequencing ; Infant ; Mutation

المؤلفون: Tian Y; School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, China., Wang X; Cancer Biology Program, University of Hawaii Cancer Center, Honolulu, HI 96813, USA., Bi Y; School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, China., Li X; College of Pharmaceutical Engineering of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China., Zhang Y; College of Pharmaceutical Engineering of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China., Yao Y; Department of Colorectal Surgery, Tianjin, Union Medical Center, Tianjin 30021, China., Zhang M; School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, China., Xu T; School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, China., Zhang Y; Department of General Practice, Nanjing Tianyinshan Hospital, Jiangsu 211100, China., Gui C; College of Pharmaceutical Sciences, Soochow University, Jiangsu 215123, China., Zhang W; Tianjin Haihe Hospital, Tianjin 300051, China., Zhang C; Department of Colorectal Surgery, Tianjin, Union Medical Center, Tianjin 30021, China., Yu H; College of Pharmaceutical Engineering of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China. Electronic address: hs_yu08@163.com., Zhang Y; School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, China. Electronic address: youcai.zhang@tju.edu.cn.

المصدر: Toxicology in vitro : an international journal published in association with BIBRA [Toxicol In Vitro] 2024 Jun; Vol. 98, pp. 105842. Date of Electronic Publication: 2024 May 16.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Pergamon Press Country of Publication: England NLM ID: 8712158 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-3177 (Electronic) Linking ISSN: 08872333 NLM ISO Abbreviation: Toxicol In Vitro Subsets: MEDLINE

مواضيع طبية MeSH: Oleanolic Acid*/analogs & derivatives , Oleanolic Acid*/pharmacology , Solute Carrier Organic Anion Transporter Family Member 1B3*/metabolism , Liver-Specific Organic Anion Transporter 1*/metabolism, Humans ; HEK293 Cells ; Hep G2 Cells ; Saponins/pharmacology ; Glycyrrhetinic Acid/pharmacology ; Glycyrrhetinic Acid/analogs & derivatives

المؤلفون: Gabor-Worwa E; Department of Drug Metabolism and Pharmacokinetics, Ryvu Therapeutics S.A., Sternbacha 2 Street, 30-394, Krakow, Poland. ewelina.gabor-worwa@ryvu.com.; Department of Analytical Chemistry and Biochemistry, Faculty of Materials Science and Ceramics, AGH University of Krakow, Mickiewicza 30 Street, 30-059, Krakow, Poland. ewelina.gabor-worwa@ryvu.com., Kowal-Chwast A; Department of Drug Metabolism and Pharmacokinetics, Ryvu Therapeutics S.A., Sternbacha 2 Street, 30-394, Krakow, Poland.; Department of Analytical Chemistry and Biochemistry, Faculty of Materials Science and Ceramics, AGH University of Krakow, Mickiewicza 30 Street, 30-059, Krakow, Poland., Gaud N; Department of Drug Metabolism and Pharmacokinetics, Ryvu Therapeutics S.A., Sternbacha 2 Street, 30-394, Krakow, Poland., Gogola D; Department of Drug Metabolism and Pharmacokinetics, Ryvu Therapeutics S.A., Sternbacha 2 Street, 30-394, Krakow, Poland., Littlewood P; Department of Drug Metabolism and Pharmacokinetics, Ryvu Therapeutics S.A., Sternbacha 2 Street, 30-394, Krakow, Poland., Smoluch M; Department of Analytical Chemistry and Biochemistry, Faculty of Materials Science and Ceramics, AGH University of Krakow, Mickiewicza 30 Street, 30-059, Krakow, Poland., Brzózka K; Department of Drug Metabolism and Pharmacokinetics, Ryvu Therapeutics S.A., Sternbacha 2 Street, 30-394, Krakow, Poland., Kus K; Department of Drug Metabolism and Pharmacokinetics, Ryvu Therapeutics S.A., Sternbacha 2 Street, 30-394, Krakow, Poland.

المصدر: European journal of drug metabolism and pharmacokinetics [Eur J Drug Metab Pharmacokinet] 2024 May; Vol. 49 (3), pp. 393-403. Date of Electronic Publication: 2024 Apr 20.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Springer France Country of Publication: France NLM ID: 7608491 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2107-0180 (Electronic) Linking ISSN: 03787966 NLM ISO Abbreviation: Eur J Drug Metab Pharmacokinet Subsets: MEDLINE

مواضيع طبية MeSH: Glucuronosyltransferase*/metabolism , Telmisartan*/pharmacokinetics , Telmisartan*/metabolism , Microsomes, Liver*/metabolism , Glucuronides*/metabolism , Solute Carrier Organic Anion Transporter Family Member 1B3*/metabolism, Humans ; Liver/metabolism ; Liver/enzymology ; Metabolic Clearance Rate ; Tandem Mass Spectrometry/methods ; Hepatocytes/metabolism ; Models, Biological ; Chromatography, Liquid/methods ; Benzoates/pharmacokinetics ; Benzoates/metabolism