المؤلفون: Kasper Hoebe, Shrinivas Bishu, John Y. Kao, Varsha Ganesan, Ankit Sharma, Yanfen Yang, Chang Zeng, Rodney D. Newberry, Sahiti Marella, Simon P. Hogan, Philip D. King, Ariel Munitz, Jazib Uddin, Taeko K. Noah, Lee A. Denson, Andrew R. Patterson, Simone Vanoni, Lisa Waggoner, Senad Divanovic, Paul S. Foster, Michael J. Rosen, S. M. S. Tomar

المصدر: Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 4, Pp 1479-1502 (2021)

مصطلحات موضوعية: CD4+ T Cells, mLN, mesenteric lymph node, Th, T-helper cell, Cell, RC799-869, mTORC1, Paired Immunoglobulin Receptor, PIR-B, paired immunoglobulin-like receptor B, GAP, GTPase-activating protein, Mice, PCR, polymerase chain reaction, ERK, extracellular signal-regulated kinase, GTP, guanosine triphosphate, RAR-related orphan receptor gamma, T-Lymphocyte Subsets, Interleukin 17, DEG, differentially expressed gene, LP, lamina propria, Intestinal Mucosa, Receptors, Immunologic, Receptor, Original Research, GFP, green fluorescent protein, Mice, Knockout, TNF, tumor necrosis factor, IBD, inflammatory bowel disease, Interleukin-17, Gastroenterology, DU, deep ulcer, ILC, innate lymphoid cell, mTORC1, mammalian target of rapamycin complex 1, Diseases of the digestive system. Gastroenterology, Colitis, Immunohistochemistry, mRNA, messenger RNA, Interleukin-10, iCD, ileal involvement Crohn’s disease, medicine.anatomical_structure, LILRB3, leukocyte immunoglobulin-like receptor subfamily B member 3, Disease Susceptibility, SHP, Src-homology region 2 domain-containing phosphatase, Signal Transduction, TSC, tuberous sclerosis, Cell Survival, T cell, Biology, Proinflammatory cytokine, Immunophenotyping, Immunomodulation, p-ERK, phosphorylated extracellular signal-regulated kinase, cCD, colonic-only involvement Crohn’s disease, medicine, CD, Crohn’s disease, Animals, IFN, interferon, Interleukin-7 receptor, RPKM, reads per kb of transcript, per million mapped reads, Hepatology, Gene Expression Profiling, Inflammatory Bowel Disease, ITIM, immunoreceptor tyrosine-based inhibitory motif, Inflammatory Bowel Diseases, Molecular biology, WT, wild-type, IL, interleukin, Disease Models, Animal, Gene Expression Regulation, TRM, tissue resident memory, Immunologic Memory, Biomarkers, Q, quartile

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5bc9234d68120dd2171e099da6a99f4
http://europepmc.org/articles/PMC8531983

المؤلفون: Michael Dougan

المصدر: Gastroenterology

مصطلحات موضوعية: Immunotherapy Colitis, ICI, immune checkpoint inhibitor, Immune checkpoint inhibitors, HV, healthy volunteer, PD-1, programmed cell death protein 1, cDNA, complementary DNA, Full Report: Basic and Translational—Alimentary Tract, Text mining, medicine, Humans, Ulcerative Colitis, IFNG, interferon gamma, Colitis, Immune Checkpoint Inhibitors, Original Research, DCC, anti–CTLA-4/PD-1 dual checkpoint inhibitor colitis, Hepatology, FMT, fecal microbiota transplantation, business.industry, UCEIS, Ulcerative Colitis Endoscopic Index of Severity, scRNA, single-cell RNA, Gastroenterology, TRM, tissue resident memory T cell, medicine.disease, RNASeq, RNA sequencing, PDC, anti–PD-1-monotherapy colitis, UC, ulcerative colitis, Tofacitinib, Immunology, Checkpoint Colitis, DCNC, anti–CTLA-4/PD-1 dual checkpoint inhibitor no colitis, business, irAE, immune-related adverse event

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d508777d919774e7906b97c8d1b115cf
https://doi.org/10.1053/j.gastro.2021.07.007

المؤلفون: Ralph S. Baric, Michael R. Betts, Olesya Palko, Chi Wai Lau, Ajinkya Pattekar, Ali Naji, Lisa C. Lindesmith, Lena S. Mayer, Paul D. Brewer-Jensen, Chengyang Liu, Meenakshi Bewtra, E. John Wherry, Vesselin T. Tomov

المصدر: Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 5, Pp 1267-1289 (2021)

مصطلحات موضوعية: Male, 0301 basic medicine, Tet+, tetramer-positive, Cellular immunity, RC799-869, CD8-Positive T-Lymphocytes, DMSO, dimethyl sulfoxide, Norovirus Tetramers, Epitope, Epitopes, T Cell Epitopes, 0302 clinical medicine, HLA Antigens, LP, lamina propria, Cytotoxic T cell, TRM, tissue-resident memory T cell, TEM, effector memory T cell, Caliciviridae Infections, Original Research, TNF, tumor necrosis factor, Effector, Gastroenterology, Diseases of the digestive system. Gastroenterology, Middle Aged, Healthy Volunteers, Intestines, Vaccination, Editorial, LPMC, lamina propria mononuclear cell, SPL, splenocyte, Female, FACS, fluorescence-activated cell sorter, HBGA, ABH histo-blood group antigens, 030211 gastroenterology & hepatology, Adult, PBMC, peripheral blood mononuclear cell, Norovirus-Specific T Cells, PBS, phosphate-buffered saline, Biology, Peripheral blood mononuclear cell, Young Adult, 03 medical and health sciences, FBS, fetal bovine serum, ORF, open reading frame, Peptide Library, Immunity, NoV, norovirus, MLN, mesenteric lymph node, Humans, MNV, mouse norovirus, TCM, central memory T cell, IFN-γ, interferon gamma, Hepatology, Norovirus, PGM, porcine gastric mucin, Virology, IL, interleukin, 030104 developmental biology, VLP, virus-like particle, Leukocytes, Mononuclear, IEDB, Immune Epitope Database, TEMRA, effector memory T cell re-expressing CD45RA, Norovirus TRM, CD8

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1e0b504252133cddc455e553314399c
https://doi.org/10.1016/j.jcmgh.2020.12.012

المؤلفون: Wen Li, Hiroshi Kurihara, Chang Yan, Zhuo Luo, Rong-Rong He, Yi-Fang Li, Robert Dallmann, Xue Li

المصدر: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 10, Iss 3, Pp 383-398 (2020)

مصطلحات موضوعية: TRKA, tropomyosin receptor kinase A, CTCF, CCCTC-binding factor, GREs, GR response elements, viruses, Cell, GRs, glucocorticoid receptors, SGKs, serum and glucocorticoid-regulated protein kinases, Stimulation, Review, PTMs, post-translational modifications, Herpes simplex virus type 1, medicine.disease_cause, 0302 clinical medicine, NK cells, natural killer cells, REST, RE1-silencing transcription factor, H3K9, histone H3 on lysines 9, sncRNAs, small non-coding RNAs, HSV-1, herpes simplex virus type 1, General Pharmacology, Toxicology and Pharmaceutics, ICP, infected cell polypeptide, MOI, multiplicity of infection, 0303 health sciences, PDK1, pyruvate dehydrogenase lipoamide kinase isozyme 1, TRIM14, tripartite motif-containing 14, PRRs, pattern-recognition receptors, OCT-1, octamer binding protein 1, Reactivation, HSV-1, RANKL, receptor activator of NF-κB ligands, T3, thyroid hormone, humanities, medicine.anatomical_structure, 4E-BP, eIF4E-binding protein, CPE, cytopathic effect, 030220 oncology & carcinogenesis, Latency, HPK, herpetic simplex keratitis, AD, Alzheimer's disease, DCs, dendritic cells, TCM, traditional Chinese medicine, TRM, tissue resident memory T cells, Recurrent infections, HPT axis, hypothalamic–pituitary–thyroid axis, LAT, latency-associated transcripts, SIRT1, sirtuin 1, AMPK, AMP-dependent kinase, NGF, nerve growth factor, TK, thymidine kinase, DEX, dexamethasone, HPA axis, hypothalamo–pituitary–adrenal axis, mTOR, mammalian target of rapamycin, MAVS, mitochondrial antiviral-signaling protein, ORFs, open reading frames, Biology, Stress, CNS, central nervous system, Inhibitory postsynaptic potential, AKT, protein kinase B, HCF-1, host cell factor 1, Virus, 03 medical and health sciences, ROS, reactive oxygen species, CORT, corticosterone, PRC1, protein regulator of cytokinesis 1, PAMPs, pathogen-associated molecular patterns, medicine, Latency (engineering), 030304 developmental biology, Balance (ability), PML, promyelocytic leukemia protein, IRF3, interferon regulatory factor 3, lcsh:RM1-950, ND10, nuclear domains 10, LSD1, lysine-specific demethylase 1, CTL, cytotoxic T lymphocyte, HDACs, histone deacetylases, LRF, Luman/CREB3 recruitment factor, CoREST, REST corepressor 1, lcsh:Therapeutics. Pharmacology, cGAS, cyclic GMP-AMP synthase, Herpes simplex virus, TG, trigeminal ganglia, Susceptibility, PI3K, phosphoinositide 3-kinases, DAMPs, damage-associated molecular patterns, Immunology, PNS, peripheral nervous system, BCL-2, B-cell lymphoma 2, KLF15, Krüppel-like transcription factor 15

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72e8bd4a9163466778ab2c0a48ebad5d
https://doi.org/10.1016/j.apsb.2019.06.005

المؤلفون: Michael Rosenblum, Victoire Gouirand, Joshua M. Moreau

المصدر: JID Innovations, Vol 1, Iss 2, Pp 100014-(2021)
JID Innovations
JID innovations : skin science from molecules to population health, vol 1, iss 2

مصطلحات موضوعية: regulatory T cell, HF, Trm, DETC, Review, DC, progressive multifocal leukoencephalopathy, Extracellular matrix, DC, dendritic cell, Th, 2.1 Biological and endogenous factors, Aetiology, Skin, atopic dermatitis, hair follicle, biology, Cell adhesion molecule, HF, hair follicle, leukocyte adhesion deficiency, Adhesion, Cell biology, ECM, extracellular matrix, Treg, medicine.anatomical_structure, RL1-803, Selectin, dendritic cell, Regulatory T cell, LAD, leukocyte adhesion deficiency, extracellular matrix, 1.1 Normal biological development and functioning, Integrin, JC, tissue-resident memory, Treg, regulatory T cell, dendritic epidermal γδ T cell, Dermatology, BM, Underpinning research, PML, progressive multifocal leukoencephalopathy, T helper, medicine, DETC, dendritic epidermal γδ T cell, Th, T helper, Leukocyte adhesion deficiency, ECM, LAD, PML, Inflammatory and immune system, AD, Dendritic cell, Trm, tissue-resident memory, AD, atopic dermatitis, medicine.disease, basement membrane, JC, John Cunningham, BM, basement membrane, John Cunningham, biology.protein

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25034e8c4fb05726ac0451fd6623653f
http://www.sciencedirect.com/science/article/pii/S266702672100014X

المؤلفون: Lisanne, Lutter, Britt, Roosenboom, Eelco C, Brand, José J, Ter Linde, Bas, Oldenburg, Ellen G, van Lochem, Carmen S, Horjus Talabur Horje, Femke, van Wijk

المصدر: Cellular and Molecular Gastroenterology and Hepatology

مصطلحات موضوعية: HBSS, Hank’s Balanced Salt Solution, FDR, false discovery rate, log2FC, log2 fold change, chemical and pharmacologic phenomena, CD8-Positive T-Lymphocytes, Lymphocyte Activation, Mucosal-Associated Invariant T Cells, Anti-T Cell Trafficking Agents, Immunophenotyping, Memory T Cells, CD8+ Tissue-Resident T Cell, Ileum, HBI, Harvey-Bradshaw index, Gut Compartmentalization, CD, Crohn’s disease, Homeostasis, Humans, Intestinal Mucosa, NES, normalized enrichment score, Trm, tissue-resident memory T cell, Original Research, PBST, phosphate-buffered saline containing 0.1% Tween-20, TNF, tumor necrosis factor, IBD, inflammatory bowel disease, Gene Expression Profiling, hemic and immune systems, HC, healthy control, IL, interleukin, Gene Expression Regulation, Organ Specificity, GzmK, granzyme K, CRP, C-reactive protein, IMC, imaging mass cytometry, BSA, bovine serum albumin, FCS, fetal calf serum, Transcriptome, Biomarkers

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::23ee6f13920597173f824ea4a0dc8fa7
https://pubmed.ncbi.nlm.nih.gov/34224909

المؤلفون: Ji Hye Kim, Jung Won Park, Thomas S. Kupper, Jungsoo Lee, Ke Lun Zhang, Youdong Pan, Kyung Hee Park, Seo Hyeong Kim, Jongsun Lee, Ji Yeon Noh, HyeRan Kim, Chang Ook Park, Bomi Kim, Kyoung Yong Jeong, Kwang Hoon Lee, Howard Chu, Zheng-wang Sun

المصدر: EBioMedicine, Vol 58, Iss, Pp 102879-(2020)
EBioMedicine

مصطلحات موضوعية: 0301 basic medicine, CD4-Positive T-Lymphocytes, Male, Research paper, AHR, Airway hyperresponsiveness, medicine.medical_treatment, Th1, Type 1 helper T cells, lcsh:Medicine, AA, Allergic asthma, medicine.disease_cause, AR, Allergic rhinitis, Mice, 0302 clinical medicine, Allergen, EASI, Eczema area and severity index, IL-17A, TRC, The RNAi Consortium, D. farinae, Dermatophagoides farinae, TSLP, Thymic stromal lymphopoietin, Sensitization, Cells, Cultured, Oligonucleotide Array Sequence Analysis, lcsh:R5-920, medicine.diagnostic_test, Cell Polarity, Fatty-acid-binding protein 5, General Medicine, Atopic dermatitis, Middle Aged, Up-Regulation, Real-time polymerase chain reaction, Cytokine, medicine.anatomical_structure, ELISA, Enzyme-linked immunosorbent assay, 030220 oncology & carcinogenesis, Disease Progression, AD, Atopic dermatitis, Biomarker (medicine), Female, TRM, Tissue-resident memory T, Th17, lcsh:Medicine (General), HC, Healthy controls, Atopic march, Adult, Genetic Markers, Thymic stromal lymphopoietin, Fatty Acid-Binding Proteins, General Biochemistry, Genetics and Molecular Biology, Flow cytometry, Dermatitis, Atopic, shRNA, Short-hairpin ribonucleic acid, 03 medical and health sciences, Young Adult, AM, Atopic march, medicine, Animals, Humans, Antigens, Dermatophagoides, HDM, House dust mite, FABP, Fatty acid-binding protein, E-FABP, Epidermal fatty acid-binding protein, KO, knockout, business.industry, Th2, Type 2 helper T cells, lcsh:R, Dendritic Cells, SDS, Sodium dodecyl sulfate, medicine.disease, ROR, Retinoic acid-related orphan receptor, Coculture Techniques, Disease Models, Animal, FABP5L, Fatty acid-binding protein5-like, 030104 developmental biology, Case-Control Studies, Immunology, Th17, Type 17 helper T cells, Th17 Cells, Der f 1, Dermatophagoides farinae 1, business, qRT-PCR, Quantitative real-time polymerase chain reaction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e09dac8f75a65d7395b7b64a1ba4bc1a
http://www.sciencedirect.com/science/article/pii/S2352396420302541

المؤلفون: Polakova A; Department of Dermatology and Allergology, Philipps-Universität Marburg, Marburg, Germany., Hudemann C; Department of Dermatology and Allergology, Philipps-Universität Marburg, Marburg, Germany., Wiemers F; Department of Gynecology and Obstetrics, Philipps-Universität Marburg, Marburg, Germany., Kadys A; Department of Gynecology and Obstetrics, Philipps-Universität Marburg, Marburg, Germany., Gremke N; Department of Gynecology and Obstetrics, Philipps-Universität Marburg, Marburg, Germany., Lang M; Center for Human Genetics, Philipps-Universität Marburg, Marburg, Germany., Zwiorek L; Department of Gynecology and Obstetrics, Philipps-Universität Marburg, Marburg, Germany., Pfützner W; Department of Dermatology and Allergology, Philipps-Universität Marburg, Marburg, Germany., Hertl M; Department of Dermatology and Allergology, Philipps-Universität Marburg, Marburg, Germany., Möbs C; Department of Dermatology and Allergology, Philipps-Universität Marburg, Marburg, Germany., Zimmer CL; Department of Dermatology and Allergology, Philipps-Universität Marburg, Marburg, Germany.

المصدر: JID innovations : skin science from molecules to population health [JID Innov] 2022 Sep 07; Vol. 3 (1), pp. 100155. Date of Electronic Publication: 2022 Sep 07 (Print Publication: 2023).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier B.V. on behalf of the Society for Investigative Dermatology Country of Publication: Netherlands NLM ID: 101776173 Publication Model: eCollection Cited Medium: Internet ISSN: 2667-0267 (Electronic) Linking ISSN: 26670267 NLM ISO Abbreviation: JID Innov Subsets: PubMed not MEDLINE

المؤلفون: Moreau JM; Department of Dermatology, University of California San Francisco, San Francisco, California, USA., Gouirand V; Department of Dermatology, University of California San Francisco, San Francisco, California, USA., Rosenblum MD; Department of Dermatology, University of California San Francisco, San Francisco, California, USA.

المصدر: JID innovations : skin science from molecules to population health [JID Innov] 2021 Apr 30; Vol. 1 (2), pp. 100014. Date of Electronic Publication: 2021 Apr 30 (Print Publication: 2021).

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Elsevier B.V. on behalf of the Society for Investigative Dermatology Country of Publication: Netherlands NLM ID: 101776173 Publication Model: eCollection Cited Medium: Internet ISSN: 2667-0267 (Electronic) Linking ISSN: 26670267 NLM ISO Abbreviation: JID Innov Subsets: PubMed not MEDLINE

المؤلفون: Yan C; Guangdong Engineering Research Center of Chinese Medicine & Disease Susceptibility, Jinan University, Guangzhou 510632, China.; International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Chinese Ministry of Education (MOE), School of Pharmacy, Jinan University, Guangzhou 510632, China., Luo Z; Guangdong Engineering Research Center of Chinese Medicine & Disease Susceptibility, Jinan University, Guangzhou 510632, China.; International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Chinese Ministry of Education (MOE), School of Pharmacy, Jinan University, Guangzhou 510632, China., Li W; Guangdong Engineering Research Center of Chinese Medicine & Disease Susceptibility, Jinan University, Guangzhou 510632, China.; International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Chinese Ministry of Education (MOE), School of Pharmacy, Jinan University, Guangzhou 510632, China., Li X; Institute of Atmospheric Environmental Safety and Pollution Control, Jinan University, Guangzhou 510632, China., Dallmann R; Warwick Medical School, University of Warwick, Coventry CV4 7AL, UK., Kurihara H; Guangdong Engineering Research Center of Chinese Medicine & Disease Susceptibility, Jinan University, Guangzhou 510632, China.; International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Chinese Ministry of Education (MOE), School of Pharmacy, Jinan University, Guangzhou 510632, China., Li YF; Guangdong Engineering Research Center of Chinese Medicine & Disease Susceptibility, Jinan University, Guangzhou 510632, China.; International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Chinese Ministry of Education (MOE), School of Pharmacy, Jinan University, Guangzhou 510632, China., He RR; Guangdong Engineering Research Center of Chinese Medicine & Disease Susceptibility, Jinan University, Guangzhou 510632, China.; International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Chinese Ministry of Education (MOE), School of Pharmacy, Jinan University, Guangzhou 510632, China.

المصدر: Acta pharmaceutica Sinica. B [Acta Pharm Sin B] 2020 Mar; Vol. 10 (3), pp. 383-398. Date of Electronic Publication: 2019 Jun 22.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101600560 Publication Model: Print-Electronic Cited Medium: Print ISSN: 2211-3835 (Print) Linking ISSN: 22113835 NLM ISO Abbreviation: Acta Pharm Sin B Subsets: PubMed not MEDLINE