-
1كتاب إلكتروني
المساهمون: Volkmar, Fred R., editorAff1
المصدر: Encyclopedia of Autism Spectrum Disorders. :4923-4923
-
2
المؤلفون: Kasper Hoebe, Shrinivas Bishu, John Y. Kao, Varsha Ganesan, Ankit Sharma, Yanfen Yang, Chang Zeng, Rodney D. Newberry, Sahiti Marella, Simon P. Hogan, Philip D. King, Ariel Munitz, Jazib Uddin, Taeko K. Noah, Lee A. Denson, Andrew R. Patterson, Simone Vanoni, Lisa Waggoner, Senad Divanovic, Paul S. Foster, Michael J. Rosen, S. M. S. Tomar
المصدر: Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 4, Pp 1479-1502 (2021)مصطلحات موضوعية: CD4+ T Cells, mLN, mesenteric lymph node, Th, T-helper cell, Cell, RC799-869, mTORC1, Paired Immunoglobulin Receptor, PIR-B, paired immunoglobulin-like receptor B, GAP, GTPase-activating protein, Mice, PCR, polymerase chain reaction, ERK, extracellular signal-regulated kinase, GTP, guanosine triphosphate, RAR-related orphan receptor gamma, T-Lymphocyte Subsets, Interleukin 17, DEG, differentially expressed gene, LP, lamina propria, Intestinal Mucosa, Receptors, Immunologic, Receptor, Original Research, GFP, green fluorescent protein, Mice, Knockout, TNF, tumor necrosis factor, IBD, inflammatory bowel disease, Interleukin-17, Gastroenterology, DU, deep ulcer, ILC, innate lymphoid cell, mTORC1, mammalian target of rapamycin complex 1, Diseases of the digestive system. Gastroenterology, Colitis, Immunohistochemistry, mRNA, messenger RNA, Interleukin-10, iCD, ileal involvement Crohn’s disease, medicine.anatomical_structure, LILRB3, leukocyte immunoglobulin-like receptor subfamily B member 3, Disease Susceptibility, SHP, Src-homology region 2 domain-containing phosphatase, Signal Transduction, TSC, tuberous sclerosis, Cell Survival, T cell, Biology, Proinflammatory cytokine, Immunophenotyping, Immunomodulation, p-ERK, phosphorylated extracellular signal-regulated kinase, cCD, colonic-only involvement Crohn’s disease, medicine, CD, Crohn’s disease, Animals, IFN, interferon, Interleukin-7 receptor, RPKM, reads per kb of transcript, per million mapped reads, Hepatology, Gene Expression Profiling, Inflammatory Bowel Disease, ITIM, immunoreceptor tyrosine-based inhibitory motif, Inflammatory Bowel Diseases, Molecular biology, WT, wild-type, IL, interleukin, Disease Models, Animal, Gene Expression Regulation, TRM, tissue resident memory, Immunologic Memory, Biomarkers, Q, quartile
-
3
المؤلفون: Mohammad Wali Naseri, Habib Ahmad Esmat
المصدر: Annals of Medicine and Surgery
مصطلحات موضوعية: medicine.medical_specialty, Angiomyolipoma, medicine.medical_treatment, TSC, Tuberous sclerosis complex, Malignancy, 03 medical and health sciences, Tuberous sclerosis, Pseudoaneurysm, 0302 clinical medicine, Case report, medicine, Embolization, business.industry, General Medicine, Hypervascularity, Bleed, medicine.disease, AMLs, Angiomyolipomas, 030220 oncology & carcinogenesis, Renal pseudoaneurysm, 030211 gastroenterology & hepatology, Surgery, Radiology, Presentation (obstetrics), business
-
4
المؤلفون: Bruno Guedes, Baldi, Elzbieta, Radzikowska, Vincent, Cottin, Daniel F, Dilling, Ali, Ataya, Carlos Roberto Ribeiro, Carvalho, Sergio, Harari, Matthew, Koslow, Jan C, Grutters, Yoshikazu, Inoue, Nishant, Gupta, Simon R, Johnson
المصدر: Chest
مصطلحات موضوعية: RT-PCR, reverse-transcription polymerase chain reaction, Lung Neoplasms, DLCO, diffusing capacity of the lungs for carbon monoxide, Tumor Suppressor Proteins, Settore MED/10 - Malattie dell'Apparato Respiratorio, BMI, body mass index, mTOR, mechanistic target of rapamycin, COVID-19, LAM, patient outcome assessment, FEV1, forced expiratory volume in the first second, Hospitalization, LAM, lymphangioleiomyomatosis, sirolimus, Tuberous Sclerosis Complex 2 Protein, FVC, forced vital capacity, Research Letter, UK, United Kingdom, Humans, Lymphangioleiomyomatosis, TSC, tuberous sclerosis complex, USA, United States of America, COVID-19, coronavirus disease 19, TSC
-
5
المؤلفون: Hee-Seok Kweon, Si-Hyong Jang, Kae Won Cho, Dahee Choi, Dae Ho Lee, Sang Gyune Kim, Tom Huh, Eunyong Ahn, Eunyoung Moon, Je Kyung Seong, Yongmin Kwon, Young Seok Kim, Seung Hoi Koo, Geum-Sook Hwang, Hye-Sook Han
المصدر: Molecular Metabolism
Molecular Metabolism, Vol 55, Iss, Pp 101402-(2022)مصطلحات موضوعية: Cirrhosis, Lipophagy, mTORC1, HFD, high fat diet, Sirtuin 1, Non-alcoholic Fatty Liver Disease, Nonalcoholic fatty liver disease, Internal medicine, Mice, Knockout, biology, Chemistry, Fatty liver, NAFLD, Non-alcoholic fatty liver disease, CRTC2, CREB regulated transcription co-activator 2, CRTC2, TG, triacylglycerol, Liver, Sirtuin, Lipogenesis, Original Article, miR-34a, Signal Transduction, medicine.medical_specialty, Diet, High-Fat, medicine, Autophagy, Animals, Obesity, mTORC, mammalian target of rapamycin complex, Molecular Biology, SIRT, Sirtuin, NCD, normal chow diet, Cell Biology, DIO, diet-induced obesity, medicine.disease, Lipid Metabolism, RC31-1245, Mice, Inbred C57BL, MicroRNAs, Endocrinology, Diabetes Mellitus, Type 2, biology.protein, Hepatocytes, Ectopic expression, TSC, tuberous sclerosis complex, Transcription Factors
-
6
المؤلفون: Luigi Ricciardiello, Giulia Piazzi, Chiara Alquati, Anna Prossomariti
المساهمون: Prossomariti A., Piazzi G., Alquati C., Ricciardiello L.
المصدر: Cellular and Molecular Gastroenterology and Hepatology, Vol 10, Iss 3, Pp 491-506 (2020)
Cellular and Molecular Gastroenterology and Hepatologyمصطلحات موضوعية: 0301 basic medicine, Colorectal cancer, Wnt/β-Catenin, Resistance, FZD, frizzled, mTORC1, Review, PI3K, phosphatidylinositol-3-kinase, DEPTOR, DEP domain-containing mTOR-interacting protein, Phosphatidylinositol 3-Kinases, 0302 clinical medicine, GTPase, guanosine triphosphatase, Antineoplastic Combined Chemotherapy Protocols, Crosstalk, beta Catenin, Phosphoinositide-3 Kinase Inhibitors, Kinase, Gastroenterology, Wnt signaling pathway, mTORC1, mammalian target of rapamycin complex 1, APC, adenomatous polyposis coli, eIF4E, eukaryotic translation initiation factor 4E, FOXO3A, Forkhead box O3A, MNK, Mitogen-activated Protein kinase interacting kinases, Gene Expression Regulation, Neoplastic, Crosstalk (biology), PI3K/AKT/mTORC1, CRC, colorectal cancer, PORCN, Porcupine, 030211 gastroenterology & hepatology, Colorectal Neoplasms, RAS, Rat Sarcoma, Signal Transduction, Rheb, ras homolog enriched in brain, TSC, tuberous sclerosis, 4E-BP1, 4E binding protein 1, mTOR, mammalian target of rapamycin, RNF43, ring finger protein 43, Biology, Mechanistic Target of Rapamycin Complex 1, TNKSi, tankyrase inhibitors, AKT, protein kinase B, 03 medical and health sciences, eEF2K, elongation factor 2 kinase, MEK, Mitogen-activated protein kinase kinase, Cell Line, Tumor, medicine, GSK3, glycogen synthase kinase 3, Animals, Humans, FAP, familial adenomatous polyposis, lcsh:RC799-869, Protein kinase B, PI3K/AKT/mTOR pathway, Cell Proliferation, TNKS, tankyrase, Colorectal Cancer, Hepatology, ZNRF3, zinc/ring finger 3, medicine.disease, YAP, Yes-associated protein, EGFR, epidermal growth factor receptor, Wnt Proteins, Disease Models, Animal, 030104 developmental biology, DVL, Dishevelled, Drug Resistance, Neoplasm, Catenin, Cancer research, lcsh:Diseases of the digestive system. Gastroenterology, Proto-Oncogene Proteins c-akt, LRP, low-density lipoprotein receptors 5 and 6, S6K, S6 Kinase
وصف الملف: STAMPA
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c7a306ac692719a8347e0c547725351
http://www.sciencedirect.com/science/article/pii/S2352345X20300515 -
7
المؤلفون: Nadia Badawi, Melanie Wong, Himanshu Popat, Julian Ayer, Claire M. Lawley
المصدر: JACC: Case Reports, Vol 1, Iss 3, Pp 327-331 (2019)
JACC Case Reportsمصطلحات موضوعية: medicine.medical_specialty, Case Report, mTOR, mammalian target of rapamycin, congenital heart defect, Clinical Case, Internal medicine, medicine, LVOT, left ventricular outflow tract, cancer, echocardiography, Diseases of the circulatory (Cardiovascular) system, Cardiac risk, business.industry, Sirolimus therapy, Cardiac rhabdomyoma, Cancer, medicine.disease, equipment and supplies, Sirolimus, RC666-701, Cardiology, cardiovascular system, TSC, tuberous sclerosis complex, Cardiology and Cardiovascular Medicine, business, medicine.drug
-
8
المؤلفون: Andras Perl, Christian Geier
المصدر: Autoimmunity Reviews
مصطلحات موضوعية: ULK1, Unc-51 like autophagy activating kinase, p70S6K, P70-S6 kinase, DAMP, damage-associated molecular pattern, RA, rheumatoid arthritis, Autoimmunity, Review, Antiviral immunity, Raptor, regulatory-associated protein of mTOR, medicine.disease_cause, DEPTOR, DEP domain-containing mTOR-interacting protein, SLE, systemic lupus erythematosus, DC, dendritic cell, MOG, Myelin oligodendrocyte glycoprotein, Immunology and Allergy, Lupus Erythematosus, Systemic, ANA, antinuclear antibodies, COVID-19, coronavirus disease 2019, EAE, experimental autoimmune encephalomyelitis, TH, T helper cell, EBV, Epstein-Barr virus, TNF, tumor necrosis factor, biology, TCR, T cell receptor, TOR Serine-Threonine Kinases, mTOR, mechanistic target of rapamycin, Lc3b, microtubule-associated protein 1 light chain 3β, Rictor, rapamycin-insensitive companion of mTOR, CCR7, CC-chemokine receptor 7, Acquired immune system, medicine.anatomical_structure, 4E-BP2, eukaryotic translation initiation factor 4E-binding protein 2, mTORC, mTOR complex, G6PD, glucose-6-phosphate-dehydrogenase, mTOR, Lifespan extension, PRR5, Proline-rich protein 5, medicine.symptom, Rapa, rapamycin, Mechanistic target of rapamycin, PI3K, phosphoinositide 3-kinase, medicine.drug, IKK-β, inhibitor of nuclear factor kappa-B kinase subunit beta, TLR, Toll-like receptor, Rheb, ras homolog enriched in brain, T cell, Immunology, Longevity, SIN1, Stress-activated map kinase-interacting protein 1, Treg, regulatory T cell, Inflammation, ETV7, transcription factor ETV7, FKBP8, FKBP prolyl isomerase 8, Antiviral Agents, MSU, monosodium urate, PD-1, programmed cell death protein 1, Systemic lupus erythematosus, HHV-8, human herpesvirus-8, PRAS40, proline-rich Akt substrate of 40 kDa, medicine, Humans, eiF4E, Elongation initiation factor 4E, PI3K/AKT/mTOR pathway, Aged, Sirolimus, MHC, Major histocompatibility complex, Immune cell lineage specification, Innate immune system, IFN-γ, interferon gamma, business.industry, SARS-CoV-2, S1P1, sphingosine-1-phosphate receptor 1, COVID-19, iMCD, idiopathic multicentric Castleman disease, NAC, N-Acetylcysteine, AMPK, AMP-activated protein kinase, APC, antigen-presenting cell, KSHV, Kaposi's sarcoma-associated herpesvirus, 4E-BP1, eukaryotic translation initiation factor 4E-binding protein 1, biology.protein, business, mLST8, mammalian lethal with SEC13 protein 8, TSC, tuberous sclerosis complex, FAO, fatty acid oxidation
-
9
المؤلفون: Ebru S. Selen, Michael J. Wolfgang
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: 0301 basic medicine, Male, Anabolism, mTORC1, Biochemistry, carnitine palmitoyltransferase 2 (Cpt2), Tuberous Sclerosis Complex 1 Protein, βHB, beta hydroxybutyrate, Mice, DKO, double-KO, Ketogenesis, Beta oxidation, fatty acid oxidation, TSC1L−/−, liver-specific deletion of TSC1, TGs, triglycerides, biology, Chemistry, mTOR, mechanistic target of rapamycin, Fasting, Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha, Cell biology, Phenotype, Liver, mTOR, Peroxisome proliferator-activated receptor alpha, biological phenomena, cell phenomena, and immunity, Research Article, Signal Transduction, Mechanistic Target of Rapamycin Complex 1, Cpt2L−/−, liver-specific deletion of carnitine palmitoyltransferase 2, 03 medical and health sciences, Animals, β-hydroxybutyrate (βHB), Molecular Biology, Mechanistic target of rapamycin, PI3K/AKT/mTOR pathway, PCA, principal component analysis, 030102 biochemistry & molecular biology, peroxisome proliferator-activated receptor alpha (PPARα), PPARα, peroxisome proliferator-activated receptor alpha, Carnitine O-Palmitoyltransferase, Catabolism, Cell Biology, ketogenesis, Mice, Inbred C57BL, 030104 developmental biology, biology.protein, TSC, tuberous sclerosis complex, metabolism, Gene Deletion
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da26170e74a36a230b9f59cc4986fc2c
http://europepmc.org/articles/PMC8294577 -
10
المؤلفون: Hiroyuki Mano, Masahito Kawazu, Noboru Mizushima, Kaito Mimura, Jun-Ichi Sakamaki, Hideaki Morishita
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: 0301 basic medicine, Purine, Amidophosphoribosyltransferase, mTORC1, tuberous sclerosis complex, Biochemistry, Phosphoribosylformylglycinamidine synthase, chemistry.chemical_compound, BRD4, bromodomain-containing protein 4, LC3, microtubule-associated protein 1 light chain 3, Nucleotide, Clustered Regularly Interspaced Short Palindromic Repeats, DHODH, dihydroorotate dehydrogenase, Purine metabolism, chemistry.chemical_classification, PFAS, phosphoribosylformylglycinamidine synthase, Gene Editing, biology, mTORC1, mammalian target of rapamycin complex 1, nucleotide, nucleoside/nucleotide biosynthesis, Cell biology, Pyrimidine metabolism, Carbon-Nitrogen Ligases with Glutamine as Amide-N-Donor, RHEB, Research Article, Mechanistic Target of Rapamycin Complex 1, MAGeCK, model-based analysis of genome-wide CRISPR-Cas9 knockout, 03 medical and health sciences, HEK, human embryonic kidney, CRISPR/Cas, RHEB, Ras homolog enriched in brain, Autophagy, Humans, GABARAP, γ-aminobutyric acid receptor-associated protein, Molecular Biology, mammalian target of rapamycin, 030102 biochemistry & molecular biology, phosphoribosylformylglycinamidine synthase, CAD, carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase, sgRNA, single guide RNA, Cell Biology, GeCKO, genome-scale CRISPR knockout, 030104 developmental biology, HEK293 Cells, chemistry, biology.protein, nucleoside/nucleotide metabolism, CRISPR-Cas Systems, TSC, tuberous sclerosis complex, PPAT, phosphoribosyl pyrophosphate amidotransferase
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d45dd2cb67d67cf999e1509428d95e52
http://europepmc.org/articles/PMC8191307
Full Text via ClinicalKey