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المؤلفون: Bopp, Stephanie K, Barouki, Robert, Brack, Werner, Dalla Costa, Silvia, Dorne, Jean-Lou C M, Drakvik, Paula E, Faust, Michael, Karjalainen, Tuomo K, Kephalopoulos, Stylianos, van Klaveren, Jacob, Kolossa-Gehring, Marike, Kortenkamp, Andreas, Lebret, Erik, Lettieri, Teresa, Nørager, Sofie, Rüegg, Joëlle, Tarazona, Jose V, Trier, Xenia, van de Water, Bob, van Gils, Jos, Bergman, Åke, Sub RIVM, dIRAS RA-2

المساهمون: Sub RIVM, dIRAS RA-2

المصدر: Environment International
Environment International, Vol 120, Iss, Pp 544-562 (2018)
Environment international, 120, 544. Elsevier Limited
Environment International, 120, 544-562

مصطلحات موضوعية: 0301 basic medicine, PNEC, predicted no effect concentration, SMRI, similar mixture risk indicator, 010501 environmental sciences, MoA, mode of action, 01 natural sciences, PBTK, physiologically based toxicokinetic (model), AOP, adverse outcome pathway, TTC, Threshold of Toxicological Concern, NAM, new approach methodology, Order (exchange), MCRA, Monte Carlo risk assessment tool, CMEP, chemical monitoring and emerging pollutants, lcsh:Environmental sciences, General Environmental Science, media_common, lcsh:GE1-350, IATA, integrated approach to testing and assessment, Legislature, Environmental exposure, CAG, cumulative assessment group, IPRA, integrated probabilistic risk assessment, DEB, dynamic energy budget, RDT, repeated dose systemic toxicity, Risk assessment, Exposure data, IA, independent action, DART, developmental and reproductive toxicity, EBT, effect-based tools, MSFD, Marine Strategy Framework Directive, TK, toxicokinetic, CRA, cumulative risk assessment, AO, adverse outcome, BMD, benchmark dose modelling, MCR, maximum cumulative ratio, MRA, mixture risk assessment, Complex Mixtures, PEC, predicted exposure concentration, Risk Assessment, SYRINA, systematic review and integrated assessment, Hazardous Substances, Article, 03 medical and health sciences, iPSC, induced pluripotent stem cells, EDC, endocrine disrupting chemical, LOE, lines of evidence, media_common.cataloged_instance, Animals, Humans, BQE, biological quality element, European Union, European union, Environmental planning, 0105 earth and related environmental sciences, Exposure assessment, QSAR, quantitative structure activity relationship, Research, EQS, environmental quality standard, Environmental Exposure, MEC, measured exposure concentration, Effect assessment, 030104 developmental biology, HBM, human biomonitoring, 13. Climate action, WFD, Water Framework Directive, CA, concentration addition

وصف الملف: image/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97130d1b072abd810a092d4f20c383bf
http://bura.brunel.ac.uk/handle/2438/17467

المؤلفون: Michelle R. Embry, Andrew Worth, Marlies Halder, Stephanie K. Bopp, Aude Kienzler

المصدر: The Science of the Total Environment

مصطلحات موضوعية: ECHA, European Chemicals Agency, Percentile, Environmental Engineering, 010504 meteorology & atmospheric sciences, CTD-TC, chemical toxicity distribution-threshold concentration, CY, Cyprus, MRA, mixture risk assessment, PNEC, predicted no-effect concentration, EFSA, European Food Safety Authority, SW, Sweden, 010501 environmental sciences, Ecotoxicological Threshold of Toxicological Concern, Combined exposure, 01 natural sciences, Article, AF, assessment factor, Aquatic toxicology, TTC, Threshold of Toxicological Concern, QSAR, quantitative structure–activity relationship, RQi, risk quotient for the individual substance, Statistics, Environmental Chemistry, Predicted no-effect concentration, FR, France, Aquatic toxicity, MLT, Malta, RQmix, risk quotient for a mixture, TU, toxic unit, Waste Management and Disposal, 0105 earth and related environmental sciences, Gap filling, ecoTTC, ecotoxicological Threshold of Toxicological Concern, Chemical toxicity, MOA, mode of action, PFOS, perfluorooctanesulfonic acid, STU, sum of toxic units, MEC, measured exposure concentration, Pollution, PFOA, perfluorooctanoic acid, Mode of action, CA, concentration addition, Monitoring data, REACH, Registration, Evaluation, Authorisation and Restriction of Chemicals, Environmental science, Ecotoxicity, Risk assessment

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68c23a7f68fd723a874df525838f13cb
https://doi.org/10.1016/j.scitotenv.2019.07.316

المؤلفون: Jente Boonen, Lien Taevernier, Christian Burvenich, Bart De Spiegeleer, Nathalie Roche, Lieselotte Veryser, Kathelijne Peremans

المصدر: Journal of Pharmaceutical Analysis
Journal of Pharmaceutical Analysis, Vol 4, Iss 5, Pp 303-315 (2014)

مصطلحات موضوعية: Franz diffusion cell, Pharmaceutical Science, Pharmacy, Pharmacology, Dermal exposure, Analytical Chemistry, Km, Partitioning coefficient, chemistry.chemical_compound, QbD, Quality-by-Design, Impurity, Drug Discovery, Electrochemistry, Original Research Article, ICH, International conference on harmonization, GMP, Good manufacturing practice, Spectroscopy, Medicine(all), DP, Drug product, API, Active pharmaceutical ingredient, Transdermal penetration, Permeation, Dm, Diffusion coefficient, Acetol, TTC, Threshold of toxicological concern, PG, Propylene glycol, SCCS, Scientific committee on consumer safety, EC, European commission, PBS, Phosphate buffered saline, EFCG, European fine chemical group, FDC, Franz diffusion cells, Excipients, DD, Dermal drugs, Glycerol, Health risk, PAH, Polycyclic aromatic hydrocarbon, Chromatography, SEdermal, Systemic exposure after dermal contact, Biochemistry, Genetics and Molecular Biology(all), IPEC, International pharmaceutical excipient council, lcsh:RM1-950, DS, Drug substances, Risk evaluation, lcsh:Therapeutics. Pharmacology, Jss, Transdermal steady-state flux, Specification limits, chemistry, Skin penetration, Kp, permeability coefficient, tlag, Lag time

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::502f0b057e933a2e5078b8495531257f

المؤلفون: A-N Richarz, Bruno Bienfait, Judith C. Madden, Mark T. D. Cronin, Aleksandra Mostrag, Kristi Muldoon-Jacobs, Ann M. Richard, Andrew Worth, Daniel Neagu, Kirk Arvidson, J. Marusczyk, Steven J. Enoch, Patra Volarath, Bryan Hobocienski, Oliver Sacher, James F. Rathman, Christof H. Schwab, B. Heldreth, Yang Lan, Mark D. Nelms, J. Park, Tomasz Magdziarz, Katarzyna R. Przybylak, Chihae Yang, João Vinnie Ribeiro, Vessela Vitcheva

المصدر: Computational Toxicology (Amsterdam, Netherlands)

مصطلحات موضوعية: Knowledge hub, Computer science, Health, Toxicology and Mutagenesis, OECD, Organisation for Economic Co-operation and Development, QA, Quality Assurance, AOP, Adverse Outcome Pathway, SCCS, Scientific Committee on Consumer Safety (EU), 010501 environmental sciences, SCCP, Scientific Committee on Consumer Products (EU), Toxicology, 01 natural sciences, US EPA, United States Environmental Protection Agency, LogP, Logarithm of the octanol:water partition coefficient, TTC, Threshold of Toxicological Concern, Documentation, SCCNFP, Scientific Committee of Cosmetic Products and Non-food Products intended for Consumers (EU), QD, HESS, Hazard Evaluation Support System, SCC, Science Committee on Cosmetics (EU), media_common, OpenFoodTox, EFSA’s OpenFoodTox database, CERES, Chemical Evaluation and Risk Estimation System, 0303 health sciences, Biological data, CFSAN, Center for Food Safety and Applied Nutrition, HTS, High throughput screening, CRADA, Cooperative Research and Development Agreement, PK/TK, Pharmacokinetics/Toxicokinetics, LOAEL, Lowest Observed Adverse Effect Level, Computer Science Applications, NAM, New Approach Methodology, Knowledge base, Data system, US FDA, United States Food and Drug Administration, LEL, Lowest Effect Level, NOAEL, No Observed Adverse Effect Level, PAFA, Priority-based Assessment of Food Additive database, DB, Database, Study reliability, ECHA, European Chemicals Agency, NITE, National Institute of Technology and Evaluation (Japan), ILSI, International Life Sciences Institute, QC, Quality Control, media_common.quotation_subject, EFSA, European Food Safety Authority, IUCLID, International Uniform Chemical Information Database, Article, HNEL, Highest No Effect Level, CosIng, Cosmetic Ingredient Database, Data governance, RS, NTP, National Toxicology Program, Database, NGRA, Next Generation Risk-Assessment, 03 medical and health sciences, Analogue selection, Quality (business), CMS-ID, COSMOS Identification Number, COSMOS MINIS, Minimum Inclusion Criteria of Studies in COSMOS DB, COSMOS NG, COSMOS Next Generation, 030304 developmental biology, 0105 earth and related environmental sciences, Structure (mathematical logic), Toxicity, business.industry, COSMOS DB, COSMOS Database, Public database, Data science, Guided workflow, ToxRefDB, Toxicity Reference Database, Workflow, REACH, Registration, Evaluation, Authorisation and Restriction of Chemicals, DST, Dempster Shafer Theory, business, DART, Developmental & Reproductive Toxicity

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59059941a4da805010a15ed46a1d9da6
https://researchonline.ljmu.ac.uk/id/eprint/15083/11/1-s2.0-S2468111321000232-main.pdf

المؤلفون: Wichitnithad W; Department of Analytical Development, Pharma Nueva Co., Ltd, Bangkok 10900, Thailand.; Department of Clinical Development, Pharma Nueva Co., Ltd, Bangkok 10900, Thailand., Nantaphol S; Department of Clinical Development, Pharma Nueva Co., Ltd, Bangkok 10900, Thailand., Noppakhunsomboon K; Department of Ethical Business Development, Siam Pharmaceutical Co., Ltd, Bangkok 10900, Thailand., Rojsitthisak P; Department of Food and Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok 10330, Thailand.; Center of Excellence in Natural Products for Ageing and Chronic Diseases, Chulalongkorn University, Bangkok 10330, Thailand.

المصدر: Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society [Saudi Pharm J] 2023 Feb; Vol. 31 (2), pp. 295-311. Date of Electronic Publication: 2022 Dec 24.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Saudi Pharmaceutical Society Country of Publication: Saudi Arabia NLM ID: 9705695 Publication Model: Print-Electronic Cited Medium: Print ISSN: 1319-0164 (Print) Linking ISSN: 13190164 NLM ISO Abbreviation: Saudi Pharm J Subsets: PubMed not MEDLINE

المؤلفون: Yang C; MN-AM, Columbus, OH, USA.; MN-AM Nürnberg, Germany., Cronin MTD; School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, UK., Arvidson KB; US FDA CFSAN College Park, MD, USA., Bienfait B; MN-AM Nürnberg, Germany., Enoch SJ; School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, UK., Heldreth B; Cosmetic Ingredient Review, Washington, DC, USA., Hobocienski B; MN-AM, Columbus, OH, USA., Muldoon-Jacobs K; US FDA CFSAN College Park, MD, USA., Lan Y; University of Bradford, UK., Madden JC; School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, UK., Magdziarz T; MN-AM Nürnberg, Germany., Marusczyk J; MN-AM Nürnberg, Germany., Mostrag A; MN-AM, Columbus, OH, USA., Nelms M; School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, UK., Neagu D; University of Bradford, UK., Przybylak K; School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, UK., Rathman JF; MN-AM, Columbus, OH, USA.; The Ohio State University, Columbus OH, USA., Park J; MN-AM, Columbus, OH, USA., Richarz AN; School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, UK., Richard AM; US EPA RTP, NC, USA., Ribeiro JV; MN-AM, Columbus, OH, USA., Sacher O; MN-AM Nürnberg, Germany., Schwab C; MN-AM Nürnberg, Germany., Vitcheva V; MN-AM, Columbus, OH, USA.; MN-AM Nürnberg, Germany., Volarath P; US FDA CFSAN College Park, MD, USA., Worth AP; European Commission, Joint Research Centre (JRC), Ispra, Italy.

المصدر: Computational toxicology (Amsterdam, Netherlands) [Comput Toxicol] 2021 Aug; Vol. 19, pp. 100175.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101708081 Publication Model: Print Cited Medium: Print ISSN: 2468-1113 (Print) Linking ISSN: 24681113 NLM ISO Abbreviation: Comput Toxicol Subsets: PubMed not MEDLINE

المؤلفون: Boonen J; Drug Quality and Registration (DruQuaR) Group, Faculty of Pharmaceutical Sciences, Ghent University, Harelbekestraat 72, 9000 Ghent, Belgium., Veryser L; Drug Quality and Registration (DruQuaR) Group, Faculty of Pharmaceutical Sciences, Ghent University, Harelbekestraat 72, 9000 Ghent, Belgium., Taevernier L; Drug Quality and Registration (DruQuaR) Group, Faculty of Pharmaceutical Sciences, Ghent University, Harelbekestraat 72, 9000 Ghent, Belgium., Roche N; Department of Plastic and Reconstructive Surgery, University Hospital Ghent, De Pintelaan 185, B-9000 Ghent, Belgium., Peremans K; Department of Veterinary Medical Imaging and Small Animal Orthopaedics, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B-9820 Merelbeke, Belgium., Burvenich C; Department of Comparative Physiology and Biometrics, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B-9820 Merelbeke, Belgium., De Spiegeleer B; Drug Quality and Registration (DruQuaR) Group, Faculty of Pharmaceutical Sciences, Ghent University, Harelbekestraat 72, 9000 Ghent, Belgium.

المصدر: Journal of pharmaceutical analysis [J Pharm Anal] 2014 Oct; Vol. 4 (5), pp. 303-315. Date of Electronic Publication: 2014 Jan 08.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Xi'an Jiaotong University Country of Publication: China NLM ID: 101579451 Publication Model: Print-Electronic Cited Medium: Print ISSN: 2095-1779 (Print) Linking ISSN: 22140883 NLM ISO Abbreviation: J Pharm Anal Subsets: PubMed not MEDLINE