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1
المؤلفون: Amy E. Schmidt, David Gailani, Taketoshi Ogawa, Mao-fu Sun, S. Paul Bajaj
المصدر: Biochemistry. 47:1326-1335
مصطلحات موضوعية: Models, Molecular, Proteases, Isoflurophate, Stereochemistry, medicine.medical_treatment, Biochemistry, Article, Antithrombins, Factor XIa, Factor IX, Serine, Amyloid beta-Protein Precursor, medicine, Humans, Amino Acid Sequence, Binding site, Factor XI, Protease, Chymotrypsin, biology, Chemistry, Benzamidines, Kinetics, Amino Acid Substitution, biology.protein, Carbamates, Kunitz domain, medicine.drug
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2
المؤلفون: Tetsuji Noguchi, Fumitoshi Asai, Atsuhiro Sugidachi, Miho Hayakawa, Taketoshi Ogawa, Koichi Fujimoto, Toyoki Nishimata, Riki Goto, Naoki Tanaka
المصدر: Chemical and Pharmaceutical Bulletin. 56:758-770
مصطلحات موضوعية: Male, Magnetic Resonance Spectroscopy, Stereochemistry, Substituent, In Vitro Techniques, Inhibitory postsynaptic potential, Mass Spectrometry, chemistry.chemical_compound, Acetic acid, Cricetinae, Drug Discovery, Animals, Humans, Moiety, Blood Coagulation, General Chemistry, General Medicine, In vitro, chemistry, Cinnamates, Toxicity, Oral anticoagulant, Indicators and Reagents, Trypsin Inhibitors, Ex vivo, Factor Xa Inhibitors
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56cadaa22d736a9338fd59304a60a770
https://doi.org/10.1248/cpb.56.758 -
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المؤلفون: Yoichi Niitsu, Masami Hashimoto, Takashi Isobe, Joseph A. Jakubowski, Fumitoshi Asai, Ken-ichi Otsuguro, Taketoshi Ogawa, Atsuhiro Sugidachi
المصدر: European Journal of Pharmacology. 579:276-282
مصطلحات موضوعية: Adult, Male, Ticlopidine, Prasugrel, Platelet Aggregation, Administration, Oral, Thiophenes, In Vitro Techniques, Pharmacology, Drug Administration Schedule, Piperazines, Rats, Sprague-Dawley, Dogs, P2Y12, Species Specificity, Oral administration, Antithrombotic, Purinergic P2 Receptor Antagonists, Animals, Humans, Medicine, Platelet, Prasugrel Hydrochloride, Dose-Response Relationship, Drug, business.industry, Thrombosis, Middle Aged, Clopidogrel, Rats, Macaca fascicularis, Rabbits, business, Platelet Aggregation Inhibitors, medicine.drug
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4
المؤلفون: Fumitoshi Asai, Riki Goto, Miho Hayakawa, Tomoko Ozeki, Atsuhiro Sugidachi, Koichi Fujimoto, Tetsuji Noguchi, Toyoki Nishimata, Taketoshi Ogawa, Naoki Tanaka
المصدر: Chemical and Pharmaceutical Bulletin. 55:393-402
مصطلحات موضوعية: Indoles, Dose-Response Relationship, Drug, Molecular Structure, Stereochemistry, Chemistry, Anticoagulants, Callithrix, General Chemistry, General Medicine, Inhibitory postsynaptic potential, chemistry.chemical_compound, Macaca fascicularis, Mice, Cricetinae, Indoline, Drug Discovery, Animals, Humans, Factor Xa Inhibitors
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19246a6b14919bc70b02969bab195546
https://doi.org/10.1248/cpb.55.393 -
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المؤلفون: Atsuhiro Sugidachi, Koichi Fujimoto, Junichiro Fukushige, Naoki Tanaka, Yoshiro Tani, Fumitoshi Asai, Taketoshi Ogawa
المصدر: European Journal of Pharmacology. 521:156-163
مصطلحات موضوعية: Male, medicine.medical_specialty, Pyrrolidines, Time Factors, Pancreatic disease, medicine.medical_treatment, Intraperitoneal injection, Choline, Rats, Sprague-Dawley, chemistry.chemical_compound, Internal medicine, Animals, Medicine, Receptor, Serotonin, 5-HT2A, Ethionine, Amylase, Rats, Wistar, Receptor, Ligation, Pancreas, Pharmacology, Pancreatic duct, biology, business.industry, Pancreatic Ducts, Rats, Inbred Strains, Lipase, Organ Size, medicine.disease, Rats, medicine.anatomical_structure, Endocrinology, Pancreatitis, chemistry, Acute Disease, Amylases, Chronic Disease, Dietary Supplements, Serotonin 5-HT2 Receptor Antagonists, biology.protein, Acute pancreatitis, Serotonin Antagonists, business, Ceruletide, Injections, Intraperitoneal
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6
المؤلفون: Paul E. Bock, Ingrid M. Verhamme, Taketoshi Ogawa, Mao-fu Sun, David Gailani
المصدر: Journal of Biological Chemistry. 280:23523-23530
مصطلحات موضوعية: Protease, biology, Chemistry, Stereochemistry, medicine.medical_treatment, Active site, Cell Biology, Tripeptide, Cleavage (embryo), Biochemistry, Zymogen activation, medicine, biology.protein, Aprotinin, Molecular Biology, Bond cleavage, Factor IX, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e8f4b31ea54cec0db995cb9a43bdeb8c
https://doi.org/10.1074/jbc.m500894200 -
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المؤلفون: Uri Seligsohn, David Gailani, S Bulvik, John R. Toomey, Taketoshi Ogawa, Jacqueline M. Lane, Ariella Zivelin, Meytal Landau
المصدر: Journal of Thrombosis and Haemostasis. 2:1782-1789
مصطلحات موضوعية: Models, Molecular, Proteases, Factor XI Deficiency, medicine.medical_treatment, Antithrombin III, Static Electricity, Mutation, Missense, Factor IX, Serine, Thrombin, medicine, Humans, Factor XI, Binding Sites, Protease, Chemistry, Homozygote, Antithrombin, Hematology, Kinetics, Coagulation, Biochemistry, Protein Binding, medicine.drug
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8
المؤلفون: David Gailani, Amy E. Schmidt, S. Paul Bajaj, Taketoshi Ogawa
المصدر: Journal of Biological Chemistry. 279:29485-29492
مصطلحات موضوعية: Serine protease, Proteases, Chymotrypsin, biology, Stereochemistry, Chemistry, Active site, Cell Biology, Biochemistry, Serine, biology.protein, Enzyme kinetics, Kunitz domain, Oxyanion hole, Molecular Biology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::731344fce8a7752c7e7d1f3211892679
https://doi.org/10.1074/jbc.m402971200 -
9
المصدر: Biochemical Pharmacology. 63:1911-1918
مصطلحات موضوعية: Blood Platelets, medicine.medical_specialty, Platelet Aggregation, P-selectin, medicine.medical_treatment, Platelet Glycoprotein GPIIb-IIIa Complex, In Vitro Techniques, Biochemistry, Thromboxane A2, chemistry.chemical_compound, Thrombin, Internal medicine, medicine, Humans, Urea, Drug Interactions, Secretion, Platelet, Protein Phosphatase 2, Platelet-Derived Growth Factor, Pharmacology, Aspirin, biology, Chemistry, Dual Specificity Phosphatase 2, beta-Thromboglobulin, P-Selectin, Endocrinology, Alpha Granule, beta-Alanine, biology.protein, Protein Tyrosine Phosphatases, Platelet Aggregation Inhibitors, Platelet-derived growth factor receptor, medicine.drug, Prostaglandin E
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المؤلفون: Fumitoshi Asai, Hiroyuki Koike, Ryo Iwamura, Taketoshi Ogawa, Atsuhiro Sugidachi, Ken-ichi Otsuguro, Kenji Yoneda
المصدر: British Journal of Pharmacology. 132:47-54
مصطلحات موضوعية: Pharmacology, medicine.medical_specialty, Thienopyridine, medicine.drug_class, Chemistry, Irreversible antagonist, Antagonist, Receptor antagonist, Ligand (biochemistry), Adenosine diphosphate, chemistry.chemical_compound, Endocrinology, Internal medicine, medicine, Platelet aggregation inhibitor, Platelet