نتائج البحث - "Tamoxifen analogs & derivatives"

1

A multi-gram-scale stereoselective synthesis of Z-endoxifen

المؤلفون: Milroy, Lech-Gustav, Koning, Bartjan, Scheppingen, Daphne S V, Jager, Nynke G L, Beijnen, Jos H, Koek, Jan, Brunsveld, Luc, Afd Pharmacoepi & Clinical Pharmacology, Pharmacoepidemiology and Clinical Pharmacology

المساهمون: Chemical Biology, Biomedical Engineering

المصدر: Bioorganic & Medicinal Chemistry Letters, 28(8), 1352. Elsevier
Bioorganic and Medicinal Chemistry Letters, 28(8), 1352-1356. Elsevier

مصطلحات موضوعية: 0301 basic medicine, Drug, Antineoplastic Agents, Hormonal, media_common.quotation_subject, Clinical Biochemistry, Pharmaceutical Science, Phases of clinical research, Antineoplastic Agents, Pharmacology, SDG 3 – Goede gezondheid en welzijn, Biochemistry, Endoxifen, Antineoplastic Agents, Hormonal/chemical synthesis, 03 medical and health sciences, 0302 clinical medicine, SDG 3 - Good Health and Well-being, Nuclear receptors, Drug Discovery, medicine, Tamoxifen analogs, Antiestrogens, Molecular Biology, Active metabolite, Gram, media_common, Chemistry, Organic Chemistry, Hormonal/chemical synthesis, Stereoselective synthesis, Stereoisomerism, MHJBZVSGOZTKRH-IZHYLOQSSA-N, medicine.disease, Metastatic breast cancer, 3. Good health, Tamoxifen/analogs & derivatives, Tamoxifen, Z-endoxifen, 030104 developmental biology, 030220 oncology & carcinogenesis, Molecular Medicine, Stereoselectivity, medicine.drug

وصف الملف: image/pdf; application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7adb99a51b2c5363be2849cd7d7b045e
https://dspace.library.uu.nl/handle/1874/376776

View record from ScienceDirect

2

Knockout of the PKN Family of Rho Effector Kinases Reveals a Non-redundant Role for PKN2 in Developmental Mesoderm Expansion

المؤلفون: Quétier I, Jj, Marshall, Spencer-Dene B, Lachmann S, Casamassima A, Franco C, Escuin S, Jt, Worrall, Baskaran P, Rajeeve V, Howell M, Aj, Copp, Stamp G, Rosewell I, Cutillas P, Holger Gerhardt, Pj, Parker, Aj, Cameron

المساهمون: Repositório da Universidade de Lisboa

المصدر: Cell Reports
Cell Reports, Vol 14, Iss 3, Pp 440-448 (2016)
Quétier, I, Marshall, J J T, Spencer-Dene, B, Lachmann, S, Casamassima, A, Franco, C, Escuin, S, Worrall, J T, Baskaran, P, Rajeeve, V, Howell, M, Copp, A J, Stamp, G, Rosewell, I, Cutillas, P, Gerhardt, H, Parker, P J & Cameron, A J M 2016, ' Knockout of the PKN Family of Rho Effector Kinases Reveals a Non-redundant Role for PKN2 in Developmental Mesoderm Expansion ', Cell Reports, vol. 14, no. 3, pp. 440-448 . https://doi.org/10.1016/j.celrep.2015.12.049
Europe PubMed Central

مصطلحات موضوعية: Embryonic stem cells, animal structures, Protein Kinase C/deficiency, mouse embryonic fibroblasts, Myocardium/metabolism, Embryonic Development, Antineoplastic Agents, Apoptosis, Cell Movement/drug effects, Heart/growth & development, Cell Line, Protein kinase N, Mesoderm, Cell Proliferation/drug effects, Mice, Cell Movement, Genes, Reporter, Report, Animals, PKC, lcsh:QH301-705.5, Cell Proliferation, Embryonic Development/drug effects, Mice, Knockout, neural crest cells, MEF, Myocardium, Apoptosis/drug effects, Heart, Embryo, Mammalian, ES cells, PKN, 4-hydroxytamoxifen, Tamoxifen/analogs & derivatives, Mice, Inbred C57BL, Tamoxifen, Embryo, Mammalian/cytology, lcsh:Biology (General), Mesoderm/cytology, Cardiovascular and Metabolic Diseases, embryonic structures, Microscopy, Electron, Scanning, NCCs, 4-OHT, Antineoplastic Agents/pharmacology, protein kinase C