المؤلفون: Hendrix S; Department of Medical Biochemistry, Amsterdam UMC, Amsterdam Cardiovascular Sciences and Gastroenterology and Metabolism, University of Amsterdam, Amsterdam, The Netherlands., Tan JME; Department of Medical Biochemistry, Amsterdam UMC, Amsterdam Cardiovascular Sciences and Gastroenterology and Metabolism, University of Amsterdam, Amsterdam, The Netherlands., Ndoj K; Department of Medical Biochemistry, Amsterdam UMC, Amsterdam Cardiovascular Sciences and Gastroenterology and Metabolism, University of Amsterdam, Amsterdam, The Netherlands., Kingma J; Department of Medical Biochemistry, Amsterdam UMC, Amsterdam Cardiovascular Sciences and Gastroenterology and Metabolism, University of Amsterdam, Amsterdam, The Netherlands., Valiloo M; Department of Medical Biochemistry, Amsterdam UMC, Amsterdam Cardiovascular Sciences and Gastroenterology and Metabolism, University of Amsterdam, Amsterdam, The Netherlands., Zijlstra LF; Department of Medical Biochemistry, Amsterdam UMC, Amsterdam Cardiovascular Sciences and Gastroenterology and Metabolism, University of Amsterdam, Amsterdam, The Netherlands., Ottenhoff R; Department of Medical Biochemistry, Amsterdam UMC, Amsterdam Cardiovascular Sciences and Gastroenterology and Metabolism, University of Amsterdam, Amsterdam, The Netherlands., Seidah NG; Laboratory of Biochemical Neuroendocrinology, Montreal Clinical Research Institute (IRCM), University of Montreal, Montréal, Québec, Canada., Loregger A; Department of Medical Biochemistry, Amsterdam UMC, Amsterdam Cardiovascular Sciences and Gastroenterology and Metabolism, University of Amsterdam, Amsterdam, The Netherlands., Kober DL; Department of Biochemistry, The University of Texas Southwestern Medical Center, Dallas, Texas, USA., Zelcer N; Department of Medical Biochemistry, Amsterdam UMC, Amsterdam Cardiovascular Sciences and Gastroenterology and Metabolism, University of Amsterdam, Amsterdam, The Netherlands.

المصدر: Molecular and cellular biology [Mol Cell Biol] 2024; Vol. 44 (4), pp. 123-137. Date of Electronic Publication: 2024 May 15.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 8109087 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-5549 (Electronic) Linking ISSN: 02707306 NLM ISO Abbreviation: Mol Cell Biol Subsets: MEDLINE

مواضيع طبية MeSH: Proprotein Convertases*/metabolism , Proprotein Convertases*/genetics , Serine Endopeptidases*/metabolism , Serine Endopeptidases*/genetics, Animals ; Humans ; Mice ; Endoplasmic Reticulum/metabolism ; Golgi Apparatus/metabolism ; HEK293 Cells ; Liver/metabolism ; Mice, Knockout ; Proteolysis ; Signal Transduction ; Sterol Regulatory Element Binding Proteins/metabolism ; Sterol Regulatory Element Binding Proteins/genetics

المؤلفون: Jun S; Department of Biology, University of Pennsylvania, Philadelphia, PA 19104, USA; Institute for Diabetes, Obesity & Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Angueira AR; Institute for Diabetes, Obesity & Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Fein EC; Institute for Diabetes, Obesity & Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Tan JME; Institute for Diabetes, Obesity & Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Weller AH; Institute for Diabetes, Obesity & Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Cheng L; Institute for Diabetes, Obesity & Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Batmanov K; Institute for Diabetes, Obesity & Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Ishibashi J; Institute for Diabetes, Obesity & Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Sakers AP; Institute for Diabetes, Obesity & Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Stine RR; Institute for Diabetes, Obesity & Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Seale P; Institute for Diabetes, Obesity & Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address: sealep@pennmedicine.upenn.edu.

المصدر: Developmental cell [Dev Cell] 2023 Nov 06; Vol. 58 (21), pp. 2195-2205.e5. Date of Electronic Publication: 2023 Aug 29.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101120028 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-1551 (Electronic) Linking ISSN: 15345807 NLM ISO Abbreviation: Dev Cell Subsets: MEDLINE

مواضيع طبية MeSH: Adipocytes, Brown*/metabolism , Dipeptidyl Peptidase 4*/metabolism, Animals ; Mice ; Adipogenesis ; Adipose Tissue, Brown/metabolism ; Obesity/metabolism ; Thermogenesis/genetics

المؤلفون: Tan JME; Department of Medical Biochemistry, Amsterdam University Medical Centers, Amsterdam Cardiovascular Sciences, Amsterdam Gastroenterology and Metabolism, University of Amsterdam, Meibergdreef 9, 1105AZ Amsterdam, the Netherlands., van der Stoel MM; Department of Medical Biochemistry, Amsterdam University Medical Centers, Amsterdam Cardiovascular Sciences, Amsterdam Gastroenterology and Metabolism, University of Amsterdam, Meibergdreef 9, 1105AZ Amsterdam, the Netherlands., van den Berg M; Department of Medical Biochemistry, Amsterdam University Medical Centers, Amsterdam Cardiovascular Sciences, Amsterdam Gastroenterology and Metabolism, University of Amsterdam, Meibergdreef 9, 1105AZ Amsterdam, the Netherlands., van Loon NM; Department of Medical Biochemistry, Amsterdam University Medical Centers, Amsterdam Cardiovascular Sciences, Amsterdam Gastroenterology and Metabolism, University of Amsterdam, Meibergdreef 9, 1105AZ Amsterdam, the Netherlands., Moeton M; Department of Medical Biochemistry, Amsterdam University Medical Centers, Amsterdam Cardiovascular Sciences, Amsterdam Gastroenterology and Metabolism, University of Amsterdam, Meibergdreef 9, 1105AZ Amsterdam, the Netherlands., Scholl E; Department of Medical Biology, Electron Microscopy Center Amsterdam, Amsterdam UMC, Meibergdreef 9, 1105AZ Amsterdam, the Netherlands., van der Wel NN; Department of Medical Biology, Electron Microscopy Center Amsterdam, Amsterdam UMC, Meibergdreef 9, 1105AZ Amsterdam, the Netherlands., Kovačević I; Department of Physiology, Amsterdam University Medical Centers, location VUmc, Amsterdam, the Netherlands; Institute for Physiological Chemistry, Medical Faculty, Martin Luther University Halle-Wittenberg, Hollystrasse 1, 06114 Halle, Germany., Hordijk PL; Department of Physiology, Amsterdam University Medical Centers, location VUmc, Amsterdam, the Netherlands., Loregger A; Department of Medical Biochemistry, Amsterdam University Medical Centers, Amsterdam Cardiovascular Sciences, Amsterdam Gastroenterology and Metabolism, University of Amsterdam, Meibergdreef 9, 1105AZ Amsterdam, the Netherlands., Huveneers S; Department of Medical Biochemistry, Amsterdam University Medical Centers, Amsterdam Cardiovascular Sciences, Amsterdam Gastroenterology and Metabolism, University of Amsterdam, Meibergdreef 9, 1105AZ Amsterdam, the Netherlands. Electronic address: s.huveneers@amsterdamumc.nl., Zelcer N; Department of Medical Biochemistry, Amsterdam University Medical Centers, Amsterdam Cardiovascular Sciences, Amsterdam Gastroenterology and Metabolism, University of Amsterdam, Meibergdreef 9, 1105AZ Amsterdam, the Netherlands. Electronic address: n.zelcer@amsterdamumc.nl.

المصدر: Cell reports [Cell Rep] 2020 Aug 04; Vol. 32 (5), pp. 107944.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE

مواضيع طبية MeSH: Homeostasis* , Neovascularization, Physiologic*, Cholesterol/*metabolism , Human Umbilical Vein Endothelial Cells/*metabolism , Membrane Proteins/*metabolism , Squalene Monooxygenase/*metabolism , Ubiquitin-Protein Ligases/*metabolism, Adherens Junctions/metabolism ; Adherens Junctions/ultrastructure ; Antigens, CD/metabolism ; Cadherins/metabolism ; Gene Silencing ; HEK293 Cells ; Human Umbilical Vein Endothelial Cells/ultrastructure ; Humans

المؤلفون: Loregger A; Department of Medical Biochemistry, Amsterdam UMC, Amsterdam Cardiovascular Sciences and Gastroenterology and Metabolism, University of Amsterdam, Meibergdreef 9, 1105AZ, Amsterdam, The Netherlands., Raaben M; Oncode Institute, Division of Biochemistry, The Netherlands Cancer Institute, Plesmanlaan 121, 1066CX, Amsterdam, The Netherlands., Nieuwenhuis J; Oncode Institute, Division of Biochemistry, The Netherlands Cancer Institute, Plesmanlaan 121, 1066CX, Amsterdam, The Netherlands., Tan JME; Department of Medical Biochemistry, Amsterdam UMC, Amsterdam Cardiovascular Sciences and Gastroenterology and Metabolism, University of Amsterdam, Meibergdreef 9, 1105AZ, Amsterdam, The Netherlands., Jae LT; Oncode Institute, Division of Biochemistry, The Netherlands Cancer Institute, Plesmanlaan 121, 1066CX, Amsterdam, The Netherlands.; Gene Center and Department of Biochemistry, Ludwig-Maximilians-Universität München, Feodor Lynen-Str. 25, 81377, Munich, Germany., van den Hengel LG; Oncode Institute, Division of Biochemistry, The Netherlands Cancer Institute, Plesmanlaan 121, 1066CX, Amsterdam, The Netherlands., Hendrix S; Department of Medical Biochemistry, Amsterdam UMC, Amsterdam Cardiovascular Sciences and Gastroenterology and Metabolism, University of Amsterdam, Meibergdreef 9, 1105AZ, Amsterdam, The Netherlands., van den Berg M; Department of Medical Biochemistry, Amsterdam UMC, Amsterdam Cardiovascular Sciences and Gastroenterology and Metabolism, University of Amsterdam, Meibergdreef 9, 1105AZ, Amsterdam, The Netherlands., Scheij S; Department of Medical Biochemistry, Amsterdam UMC, Amsterdam Cardiovascular Sciences and Gastroenterology and Metabolism, University of Amsterdam, Meibergdreef 9, 1105AZ, Amsterdam, The Netherlands., Song JY; Division of Experimental Animal Pathology, The Netherlands Cancer Institute, Plesmanlaan 121, 1066CX, Amsterdam, The Netherlands., Huijbers IJ; Mouse Clinic for Cancer and Aging (MCCA) Transgenic Facility, The Netherlands Cancer Institute, Plesmanlaan 121, 1066CX, Amsterdam, The Netherlands., Kroese LJ; Mouse Clinic for Cancer and Aging (MCCA) Transgenic Facility, The Netherlands Cancer Institute, Plesmanlaan 121, 1066CX, Amsterdam, The Netherlands., Ottenhoff R; Department of Medical Biochemistry, Amsterdam UMC, Amsterdam Cardiovascular Sciences and Gastroenterology and Metabolism, University of Amsterdam, Meibergdreef 9, 1105AZ, Amsterdam, The Netherlands., van Weeghel M; Laboratory of Genetic and Metabolic Diseases and Core Facility Metabolomics, Academic Medical Center of the University of Amsterdam, Meibergdreef 9, 1105AZ, Amsterdam, The Netherlands., van de Sluis B; Department of Pediatrics, University Medical Center Groningen, Antonius Deusinglaan 1, 9713AV, Groningen, The Netherlands.; iPSC/CRISPR Center Groningen, University Medical Center Groningen, Antonius Deusinglaan 1, 9713AV, Groningen, The Netherlands., Brummelkamp T; Oncode Institute, Division of Biochemistry, The Netherlands Cancer Institute, Plesmanlaan 121, 1066CX, Amsterdam, The Netherlands. t.brummelkamp@nki.nl.; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Lazarettgasse 14, A-1090, Vienna, Austria. t.brummelkamp@nki.nl.; Cancer Genomics Center, Amsterdam, The Netherlands. t.brummelkamp@nki.nl., Zelcer N; Department of Medical Biochemistry, Amsterdam UMC, Amsterdam Cardiovascular Sciences and Gastroenterology and Metabolism, University of Amsterdam, Meibergdreef 9, 1105AZ, Amsterdam, The Netherlands. n.zelcer@amsterdamumc.nl.

المصدر: Nature communications [Nat Commun] 2020 Feb 28; Vol. 11 (1), pp. 1128. Date of Electronic Publication: 2020 Feb 28.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Signal Transduction*, Cholesterol/*metabolism , Membrane Glycoproteins/*metabolism , Membrane Proteins/*metabolism , Sterol Regulatory Element Binding Proteins/*metabolism, Animals ; Cell Line ; Embryonic Development/genetics ; Endoplasmic Reticulum/metabolism ; Gene Expression ; Golgi Apparatus/metabolism ; Haploidy ; Hepatocytes/metabolism ; Humans ; Intracellular Signaling Peptides and Proteins/genetics ; Intracellular Signaling Peptides and Proteins/metabolism ; Lipid Metabolism/genetics ; Liver/metabolism ; Membrane Glycoproteins/genetics ; Membrane Proteins/genetics ; Mice ; Mice, Inbred C57BL ; Sterol Regulatory Element Binding Proteins/genetics

المؤلفون: Tan JME; Department of Medical Biochemistry, Academic Medical Center, University of Amsterdam, Meibergdreef 15, 1105 AZ, Amsterdam, the Netherlands., Cook ECL; Department of Medical Biochemistry, Academic Medical Center, University of Amsterdam, Meibergdreef 15, 1105 AZ, Amsterdam, the Netherlands., van den Berg M; Department of Medical Biochemistry, Academic Medical Center, University of Amsterdam, Meibergdreef 15, 1105 AZ, Amsterdam, the Netherlands., Scheij S; Department of Medical Biochemistry, Academic Medical Center, University of Amsterdam, Meibergdreef 15, 1105 AZ, Amsterdam, the Netherlands., Zelcer N; Department of Medical Biochemistry, Academic Medical Center, University of Amsterdam, Meibergdreef 15, 1105 AZ, Amsterdam, the Netherlands. Electronic address: n.zelcer@amc.uva.nl., Loregger A; Department of Medical Biochemistry, Academic Medical Center, University of Amsterdam, Meibergdreef 15, 1105 AZ, Amsterdam, the Netherlands. Electronic address: a.loregger@amc.uva.nl.

المصدر: Atherosclerosis [Atherosclerosis] 2019 Feb; Vol. 281, pp. 137-142. Date of Electronic Publication: 2018 Dec 23.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Country of Publication: Ireland NLM ID: 0242543 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-1484 (Electronic) Linking ISSN: 00219150 NLM ISO Abbreviation: Atherosclerosis Subsets: MEDLINE

مواضيع طبية MeSH: Cholesterol/*biosynthesis , Hepatocytes/*enzymology , Hydroxymethylglutaryl CoA Reductases/*metabolism , Membrane Proteins/*metabolism , Squalene Monooxygenase/*metabolism , Ubiquitin-Conjugating Enzymes/*metabolism , Ubiquitin-Protein Ligases/*metabolism, Enzyme Stability ; HEK293 Cells ; Hep G2 Cells ; Humans ; Membrane Proteins/genetics ; Proteolysis ; Time Factors ; Ubiquitin-Conjugating Enzymes/genetics ; Ubiquitin-Protein Ligases/genetics ; Ubiquitination

المؤلفون: Fong JYM; Division of Clinical Dentistry, School of Dentistry, International Medical University, Kuala Lumpur, Malaysia., Tan VJH; Division of Clinical Dentistry, School of Dentistry, International Medical University, Kuala Lumpur, Malaysia., Lee JR; Division of Clinical Dentistry, School of Dentistry, International Medical University, Kuala Lumpur, Malaysia., Tong ZGM; Division of Clinical Dentistry, School of Dentistry, International Medical University, Kuala Lumpur, Malaysia., Foong YK; Division of Clinical Dentistry, School of Dentistry, International Medical University, Kuala Lumpur, Malaysia., Tan JME; Division of Clinical Dentistry, School of Dentistry, International Medical University, Kuala Lumpur, Malaysia., Parolia A; Division of Clinical Dentistry, School of Dentistry, International Medical University, Kuala Lumpur, Malaysia., Pau A; Division of Clinical Dentistry, School of Dentistry, International Medical University, Kuala Lumpur, Malaysia.

المصدر: European journal of dental education : official journal of the Association for Dental Education in Europe [Eur J Dent Educ] 2018 Aug; Vol. 22 (3), pp. 160-166. Date of Electronic Publication: 2017 Dec 20.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 9712132 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1600-0579 (Electronic) Linking ISSN: 13965883 NLM ISO Abbreviation: Eur J Dent Educ

مواضيع طبية MeSH: Compliance* , Curriculum* , Dental Audit* , Formative Feedback*, Clinical Competence/*standards , Education, Dental/*methods , Root Canal Therapy/*standards , Students, Dental/*psychology, Endodontics/education ; Humans

المؤلفون: Smith RL; Molecular Biology & Microbial Food Safety, Swammerdam Institute for Life Sciences (SILS), Faculty of Science (FNWI), University of Amsterdam, Amsterdam, The Netherlands., Tan JME; Molecular Biology & Microbial Food Safety, Swammerdam Institute for Life Sciences (SILS), Faculty of Science (FNWI), University of Amsterdam, Amsterdam, The Netherlands., Jonker MJ; RNA Biology & Applied Bioinformatics, Swammerdam Institute for Life Sciences (SILS), Faculty of Science (FNWI), University of Amsterdam, Amsterdam, The Netherlands., Jongejan A; Bioinformatics Laboratory, Clinical Epidemiology, Biostatistics and Bioinformatics, Academic Medical Center (AMC), Amsterdam, The Netherlands., Buissink T; Molecular Biology & Microbial Food Safety, Swammerdam Institute for Life Sciences (SILS), Faculty of Science (FNWI), University of Amsterdam, Amsterdam, The Netherlands., Veldhuijzen S; Molecular Biology & Microbial Food Safety, Swammerdam Institute for Life Sciences (SILS), Faculty of Science (FNWI), University of Amsterdam, Amsterdam, The Netherlands., van Kampen AHC; Bioinformatics Laboratory, Clinical Epidemiology, Biostatistics and Bioinformatics, Academic Medical Center (AMC), Amsterdam, The Netherlands.; Biosystems data analysis, Swammerdam Institute for Life Sciences (SILS), Faculty of Science (FNWI), University of Amsterdam, Amsterdam, The Netherlands., Brul S; Molecular Biology & Microbial Food Safety, Swammerdam Institute for Life Sciences (SILS), Faculty of Science (FNWI), University of Amsterdam, Amsterdam, The Netherlands., van der Spek H; Molecular Biology & Microbial Food Safety, Swammerdam Institute for Life Sciences (SILS), Faculty of Science (FNWI), University of Amsterdam, Amsterdam, The Netherlands.

المصدر: PloS one [PLoS One] 2017 Nov 02; Vol. 12 (11), pp. e0187424. Date of Electronic Publication: 2017 Nov 02 (Print Publication: 2017).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

مواضيع طبية MeSH: Anti-HIV Agents/*pharmacology , DNA-Directed DNA Polymerase/*metabolism , Mitochondria/*drug effects , Reverse Transcriptase Inhibitors/*poisoning, Animals ; Caenorhabditis elegans/drug effects ; Humans ; Reactive Oxygen Species/metabolism