المؤلفون: Ginebaugh SP; Department of Neuroscience, Center for Neuroscience, University of Pittsburgh, Pittsburgh, Pennsylvania, United States., Badawi Y; Department of Neuroscience, Center for Neuroscience, University of Pittsburgh, Pittsburgh, Pennsylvania, United States., Laghaei R; Biomedical Application Group, Pittsburgh Supercomputing Center, Carnegie Mellon University, Pittsburgh, Pennsylvania, United States., Mersky G; Biomedical Application Group, Pittsburgh Supercomputing Center, Carnegie Mellon University, Pittsburgh, Pennsylvania, United States., Wallace CJ; Biomedical Application Group, Pittsburgh Supercomputing Center, Carnegie Mellon University, Pittsburgh, Pennsylvania, United States., Tarr TB; Department of Neuroscience, Center for Neuroscience, University of Pittsburgh, Pittsburgh, Pennsylvania, United States., Kaufhold C; Department of Neuroscience, Center for Neuroscience, University of Pittsburgh, Pittsburgh, Pennsylvania, United States., Reddel S; Department of Clinical Neurology, Concord Hospital, Sydney, New South Wales, Australia., Meriney SD; Department of Neuroscience, Center for Neuroscience, University of Pittsburgh, Pittsburgh, Pennsylvania, United States.

المصدر: Journal of neurophysiology [J Neurophysiol] 2023 May 01; Vol. 129 (5), pp. 1259-1277. Date of Electronic Publication: 2023 Apr 19.

نوع المنشور: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: American Physiological Society Country of Publication: United States NLM ID: 0375404 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1598 (Electronic) Linking ISSN: 00223077 NLM ISO Abbreviation: J Neurophysiol Subsets: MEDLINE

مواضيع طبية MeSH: Lambert-Eaton Myasthenic Syndrome*/pathology, Animals ; Humans ; Calcium Channels/metabolism ; Neuromuscular Junction/metabolism ; Neurons/metabolism ; Calcium Channels, Q-Type ; Synaptotagmins ; Mammals/metabolism

المؤلفون: Sarkar D; Media Lab, MIT, Cambridge, MA, USA.; MIT Center for Neurobiological Engineering, MIT, Cambridge, MA, USA., Kang J; MIT McGovern Institute for Brain Research, MIT, Cambridge, MA, USA., Wassie AT; Department of Biological Engineering, MIT, Cambridge, MA, USA., Schroeder ME; MIT McGovern Institute for Brain Research, MIT, Cambridge, MA, USA.; Department of Brain and Cognitive Sciences, MIT, Cambridge, MA, USA., Peng Z; Department of Brain and Cognitive Sciences, MIT, Cambridge, MA, USA.; The Picower Institute for Learning and Memory, MIT, Cambridge, MA, USA., Tarr TB; Department of Physiology, University of Maryland School of Medicine, Baltimore, MD, USA., Tang AH; Department of Physiology, University of Maryland School of Medicine, Baltimore, MD, USA.; CAS Key Laboratory of Brain Function and Disease, Biomedical Sciences and Health Laboratory of Anhui Province, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China., Niederst ED; The Picower Institute for Learning and Memory, MIT, Cambridge, MA, USA., Young JZ; Department of Brain and Cognitive Sciences, MIT, Cambridge, MA, USA.; The Picower Institute for Learning and Memory, MIT, Cambridge, MA, USA., Su H; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, USA.; Department of Systems Biology, Harvard Medical School, Boston, MA, USA., Park D; MIT McGovern Institute for Brain Research, MIT, Cambridge, MA, USA., Yin P; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, USA.; Department of Systems Biology, Harvard Medical School, Boston, MA, USA., Tsai LH; Department of Brain and Cognitive Sciences, MIT, Cambridge, MA, USA. lhtsai@mit.edu.; The Picower Institute for Learning and Memory, MIT, Cambridge, MA, USA. lhtsai@mit.edu.; Broad Institute of MIT and Harvard, Cambridge, MA, USA. lhtsai@mit.edu., Blanpied TA; Department of Physiology, University of Maryland School of Medicine, Baltimore, MD, USA. TBlanpied@som.umaryland.edu.; Program in Neuroscience, University of Maryland School of Medicine, Baltimore, MD, USA. TBlanpied@som.umaryland.edu., Boyden ES; MIT Center for Neurobiological Engineering, MIT, Cambridge, MA, USA. edboyden@mit.edu.; MIT McGovern Institute for Brain Research, MIT, Cambridge, MA, USA. edboyden@mit.edu.; Department of Biological Engineering, MIT, Cambridge, MA, USA. edboyden@mit.edu.; Department of Brain and Cognitive Sciences, MIT, Cambridge, MA, USA. edboyden@mit.edu.; Koch Institute, MIT, Cambridge, MA, USA. edboyden@mit.edu.; Howard Hughes Medical Institute, Cambridge, MA, USA. edboyden@mit.edu.; Media Arts and Sciences, MIT, Cambridge, MA, USA. edboyden@mit.edu.; K. Lisa Yang Center for Bionics, MIT, Cambridge, MA, USA. edboyden@mit.edu.

المصدر: Nature biomedical engineering [Nat Biomed Eng] 2022 Sep; Vol. 6 (9), pp. 1057-1073. Date of Electronic Publication: 2022 Aug 29.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Springer Nature Country of Publication: England NLM ID: 101696896 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2157-846X (Electronic) Linking ISSN: 2157846X NLM ISO Abbreviation: Nat Biomed Eng Subsets: MEDLINE

مواضيع طبية MeSH: Microscopy*/methods , Nanostructures*, Animals ; Brain/metabolism ; Calcium Channels/metabolism ; DNA/metabolism ; Hydrogels ; Mice ; Proteins/metabolism

المؤلفون: Ginebaugh SP; Department of Neuroscience, University of Pittsburgh, Pittsburgh, PA 15260, USA., Badawi Y; Department of Neuroscience, University of Pittsburgh, Pittsburgh, PA 15260, USA., Tarr TB; Department of Neuroscience, University of Pittsburgh, Pittsburgh, PA 15260, USA., Meriney SD; Department of Neuroscience, University of Pittsburgh, Pittsburgh, PA 15260, USA.

المصدر: Biomolecules [Biomolecules] 2022 May 24; Vol. 12 (6). Date of Electronic Publication: 2022 May 24.

نوع المنشور: Journal Article; Review; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101596414 Publication Model: Electronic Cited Medium: Internet ISSN: 2218-273X (Electronic) Linking ISSN: 2218273X NLM ISO Abbreviation: Biomolecules Subsets: MEDLINE

مواضيع طبية MeSH: Autoimmune Diseases*/pathology , Lambert-Eaton Myasthenic Syndrome*/pathology, Animals ; Autoantibodies ; Calcium Channels ; Mice ; Neuromuscular Junction/pathology

المؤلفون: Held RG; Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA., Liu C; Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA., Ma K; Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA; State Key Laboratory of Brain and Cognitive Sciences, Institute of Biophysics, Chinese Academy of Sciences, and University of Chinese Academy of Sciences, Beijing 100101, China., Ramsey AM; Department of Physiology and Program in Neuroscience, University of Maryland School of Medicine, Baltimore, MD 21201, USA., Tarr TB; Department of Physiology and Program in Neuroscience, University of Maryland School of Medicine, Baltimore, MD 21201, USA., De Nola G; Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA., Wang SSH; Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA., Wang J; Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA., van den Maagdenberg AMJM; Departments of Human Genetics and Neurology, Leiden University Medical Center, 2333 ZA Leiden, the Netherlands., Schneider T; Institute for Neurophysiology, University of Cologne, Köln 50931, Germany., Sun J; State Key Laboratory of Brain and Cognitive Sciences, Institute of Biophysics, Chinese Academy of Sciences, and University of Chinese Academy of Sciences, Beijing 100101, China., Blanpied TA; Department of Physiology and Program in Neuroscience, University of Maryland School of Medicine, Baltimore, MD 21201, USA., Kaeser PS; Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA. Electronic address: kaeser@hms.harvard.edu.

المصدر: Neuron [Neuron] 2020 Aug 19; Vol. 107 (4), pp. 667-683.e9. Date of Electronic Publication: 2020 Jun 16.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 8809320 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4199 (Electronic) Linking ISSN: 08966273 NLM ISO Abbreviation: Neuron Subsets: MEDLINE

مواضيع طبية MeSH: Calcium Channels/*metabolism , Presynaptic Terminals/*metabolism , Synapses/*metabolism , Synaptic Transmission/*physiology, Animals ; Calcium/metabolism ; Calcium Channels/genetics ; Exocytosis/physiology ; Mice, Knockout ; Neurons/metabolism ; Synaptic Vesicles/metabolism

المؤلفون: Laghaei R; Biomedical Applications Group, Pittsburgh Supercomputing Center, Carnegie Mellon University , Pittsburgh, Pennsylvania., Ma J; Biomedical Applications Group, Pittsburgh Supercomputing Center, Carnegie Mellon University , Pittsburgh, Pennsylvania., Tarr TB; Department of Neuroscience, Center for Neuroscience, University of Pittsburgh , Pittsburgh, Pennsylvania., Homan AE; Department of Neuroscience, Center for Neuroscience, University of Pittsburgh , Pittsburgh, Pennsylvania., Kelly L; Department of Neuroscience, Center for Neuroscience, University of Pittsburgh , Pittsburgh, Pennsylvania., Tilvawala MS; Department of Neuroscience, Center for Neuroscience, University of Pittsburgh , Pittsburgh, Pennsylvania., Vuocolo BS; Department of Neuroscience, Center for Neuroscience, University of Pittsburgh , Pittsburgh, Pennsylvania., Rajasekaran HP; Department of Neuroscience, Center for Neuroscience, University of Pittsburgh , Pittsburgh, Pennsylvania., Meriney SD; Department of Neuroscience, Center for Neuroscience, University of Pittsburgh , Pittsburgh, Pennsylvania., Dittrich M; Biomedical Applications Group, Pittsburgh Supercomputing Center, Carnegie Mellon University , Pittsburgh, Pennsylvania.; Department of Neuroscience, Center for Neuroscience, University of Pittsburgh , Pittsburgh, Pennsylvania.; BioTeam Inc., Middleton , Massachusetts.

المصدر: Journal of neurophysiology [J Neurophysiol] 2018 Apr 01; Vol. 119 (4), pp. 1340-1355. Date of Electronic Publication: 2017 Dec 27.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: American Physiological Society Country of Publication: United States NLM ID: 0375404 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1598 (Electronic) Linking ISSN: 00223077 NLM ISO Abbreviation: J Neurophysiol Subsets: MEDLINE

مواضيع طبية MeSH: Ion Channels* , Models, Neurological* , Synaptic Vesicles*, Neuromuscular Junction/*physiology , Synaptic Transmission/*physiology, Animals ; Female ; Male ; Mice ; Rana pipiens

المؤلفون: Meriney SD; Department of Neuroscience, University of Pittsburgh, Pittsburgh, Pennsylvania., Tarr TB; Department of Neuroscience, University of Pittsburgh, Pittsburgh, Pennsylvania., Ojala KS; Department of Neuroscience, University of Pittsburgh, Pittsburgh, Pennsylvania., Wu M; Department of Neuroscience, University of Pittsburgh, Pittsburgh, Pennsylvania., Li Y; Department of Neuroscience, University of Pittsburgh, Pittsburgh, Pennsylvania., Lacomis D; Division of Neuromuscular Diseases, Departments of Neurology and Pathology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania., Garcia-Ocaña A; Diabetes, Obesity and Metabolism Institute, Icahn School of Medicine at Mount Sinai, New York, New York., Liang M; Department of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania., Valdomir G; Department of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania., Wipf P; Department of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania.

المصدر: Annals of the New York Academy of Sciences [Ann N Y Acad Sci] 2018 Jan; Vol. 1412 (1), pp. 73-81. Date of Electronic Publication: 2017 Nov 10.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review

بيانات الدورية: Publisher: New York Academy of Sciences Country of Publication: United States NLM ID: 7506858 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1749-6632 (Electronic) Linking ISSN: 00778923 NLM ISO Abbreviation: Ann N Y Acad Sci

مواضيع طبية MeSH: Lambert-Eaton Myasthenic Syndrome/*etiology, Animals ; Autoantigens ; Carcinoma, Small Cell/etiology ; Disease Models, Animal ; Humans ; Immunization, Passive ; Lambert-Eaton Myasthenic Syndrome/pathology ; Lambert-Eaton Myasthenic Syndrome/therapy ; Lung Neoplasms/etiology ; Mice ; Neuromuscular Junction/pathology ; Neuromuscular Junction/physiopathology ; Neurotransmitter Agents/physiology

المؤلفون: Tarr TB; Department of Neuroscience, Center for Neuroscience, University of Pittsburgh, Pittsburgh, PA, 15260, USA., Wipf P, Meriney SD

المصدر: Molecular neurobiology [Mol Neurobiol] 2015 Aug; Vol. 52 (1), pp. 456-63. Date of Electronic Publication: 2014 Sep 09.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Review

بيانات الدورية: Publisher: Humana Press Country of Publication: United States NLM ID: 8900963 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1559-1182 (Electronic) Linking ISSN: 08937648 NLM ISO Abbreviation: Mol Neurobiol Subsets: MEDLINE

مواضيع طبية MeSH: Lambert-Eaton Myasthenic Syndrome/*physiopathology , Lambert-Eaton Myasthenic Syndrome/*therapy , Synapses/*pathology, Animals ; Humans ; Lambert-Eaton Myasthenic Syndrome/drug therapy ; Neuromuscular Junction/drug effects ; Neuromuscular Junction/physiopathology ; Neuroprotective Agents/pharmacology ; Neuroprotective Agents/therapeutic use ; Synapses/drug effects

المؤلفون: Tarr TB; Department of Neuroscience, Center for Neuroscience, University of Pittsburgh, Pittsburgh, PA, USA Center for the Neural Basis of Cognition, University of Pittsburgh, Pittsburgh, PA, USA., Lacomis D; Division of Neuromuscular Diseases, Department of Neurology, University of Pittsburgh, Pittsburgh, PA, USA Department of Pathology, University of Pittsburgh, Pittsburgh, PA, USA., Reddel SW; Department of Clinical Neurology, Concord Hospital, Sydney, NSW, Australia., Liang M; Department of Chemistry, University of Pittsburgh, Pittsburgh, PA, USA Center for Chemical Methodologies and Library Development, University of Pittsburgh, Pittsburgh, PA, USA., Valdomir G; Department of Chemistry, University of Pittsburgh, Pittsburgh, PA, USA Center for Chemical Methodologies and Library Development, University of Pittsburgh, Pittsburgh, PA, USA., Frasso M; Department of Chemistry, University of Pittsburgh, Pittsburgh, PA, USA Center for Chemical Methodologies and Library Development, University of Pittsburgh, Pittsburgh, PA, USA., Wipf P; Department of Chemistry, University of Pittsburgh, Pittsburgh, PA, USA Center for Chemical Methodologies and Library Development, University of Pittsburgh, Pittsburgh, PA, USA., Meriney SD; Department of Neuroscience, Center for Neuroscience, University of Pittsburgh, Pittsburgh, PA, USA Center for the Neural Basis of Cognition, University of Pittsburgh, Pittsburgh, PA, USA meriney@pitt.edu.

المصدر: The Journal of physiology [J Physiol] 2014 Aug 15; Vol. 592 (16), pp. 3687-96. Date of Electronic Publication: 2014 Jul 11.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Cambridge Univ. Press Country of Publication: England NLM ID: 0266262 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-7793 (Electronic) Linking ISSN: 00223751 NLM ISO Abbreviation: J Physiol Subsets: MEDLINE

مواضيع طبية MeSH: Synaptic Potentials*, 4-Aminopyridine/*analogs & derivatives , Calcium Channel Agonists/*pharmacology , Lambert-Eaton Myasthenic Syndrome/*metabolism , Neuromuscular Junction/*drug effects , Potassium Channel Blockers/*pharmacology , Purines/*pharmacology , Thiophenes/*pharmacology, 4-Aminopyridine/pharmacology ; Amifampridine ; Animals ; Cell Line, Tumor ; Drug Synergism ; Female ; Humans ; Lambert-Eaton Myasthenic Syndrome/physiopathology ; Mice ; Neuromuscular Junction/physiopathology ; Purines/therapeutic use ; Thiophenes/therapeutic use

المؤلفون: Tarr TB; Department of Neuroscience, Center for Neuroscience, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA., Malick W, Liang M, Valdomir G, Frasso M, Lacomis D, Reddel SW, Garcia-Ocano A, Wipf P, Meriney SD

المصدر: The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2013 Jun 19; Vol. 33 (25), pp. 10559-67.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Society for Neuroscience Country of Publication: United States NLM ID: 8102140 Publication Model: Print Cited Medium: Internet ISSN: 1529-2401 (Electronic) Linking ISSN: 02706474 NLM ISO Abbreviation: J Neurosci Subsets: MEDLINE

مواضيع طبية MeSH: Calcium Channel Agonists/*therapeutic use , Lambert-Eaton Myasthenic Syndrome/*drug therapy , Purines/*therapeutic use , Thiophenes/*therapeutic use, Action Potentials/drug effects ; Adult ; Aged ; Animals ; Cell Line ; Cyclin-Dependent Kinases/antagonists & inhibitors ; Data Interpretation, Statistical ; Electrophysiological Phenomena/drug effects ; Humans ; Mice ; Mice, Transgenic ; Middle Aged ; Neuromuscular Junction/drug effects ; Neurotransmitter Agents/metabolism ; Patch-Clamp Techniques ; Phosphotransferases/metabolism ; Roscovitine

المؤلفون: Tarr TB; Department of Neuroscience, Center for Neuroscience, University of Pittsburgh, Pittsburgh, PA 15260, USA., Dittrich M, Meriney SD

المصدر: Trends in neurosciences [Trends Neurosci] 2013 Jan; Vol. 36 (1), pp. 14-22. Date of Electronic Publication: 2012 Oct 25.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.; Review

بيانات الدورية: Publisher: Elsevier Applied Science Publishing Country of Publication: England NLM ID: 7808616 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-108X (Electronic) Linking ISSN: 01662236 NLM ISO Abbreviation: Trends Neurosci Subsets: MEDLINE

مواضيع طبية MeSH: Central Nervous System/*physiology , Neuromuscular Junction/*physiology , Synapses/*physiology , Synaptic Transmission/*physiology, Animals ; Humans