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المؤلفون: Karen A. Maegley, Kephart Susan Elizabeth, Christopher P. Dillon, Manli Shi, Kristen Jensen-Pergakes, Prakash B. Palde, Ya-Li Deng, Chi-Yeh Chung, Natalie Miller, John Sherrill, Wei Liu, Ryan L. Patman, Shinji Yamazaki, Tao Xie, Fen Wang, Hieu Lam, Eleanore Hendrickson, John F. Braganza, Yuli Wang, Robert Arnold Kumpf, Shannon Karlicek Bryant, Thomas A Paul, Noah Spiegel, Martin James Wythes, Amy Nemeth, Stephanie Scales, Elizabeth A. McMillan, Michelle Tran-Dubé, Alexei Brooun, Vesta Goshtasbi, Eugene Rui, Michele McTigue, Indrawan James Mcalpine, Tatlock John H
المصدر: Molecular Cancer Therapeutics. 21:3-15
مصطلحات موضوعية: Protein-Arginine N-Methyltransferases, S-Adenosylmethionine, Cancer Research, Cell signaling, Spliceosome, Lung Neoplasms, Chemistry, Cellular differentiation, Protein arginine methyltransferase 5, Alternative splicing, Drug Resistance, Apoptosis, Cell cycle, Mice, Oncology, Carcinoma, Non-Small-Cell Lung, Cell Line, Tumor, RNA splicing, Cancer cell, Cancer research, Animals, Humans, Female, Cell Proliferation
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::621805778a73d6732ba64af7ea279a54
https://doi.org/10.1158/1535-7163.mct-21-0620 -
2دورية أكاديمية
المؤلفون: Barsyte-Lovejoy, Dalia, Li, Fengling, Oudhoff, Menno J., Tatlock, John H., Dong, Aiping, Zeng, Hong, Wu, Hong, Freeman, Spencer A., Schapira, Matthieu, Senisterra, Guillermo A., Kuznetsova, Ekaterina, Marcellus, Richard, Allali-Hassani, Abdellah, Kennedy, Steven, Lambert, Jean-Philippe, Couzens, Amber L., Aman, Ahmed, Gingras, Anne-Claude, Al-Awar, Rima, Fish, Paul V., Gerstenberger, Brian S., Roberts, Lee, Benn, Caroline L., Grimley, Rachel L., Braam, Mitchell J. S., Rossi, Fabio M. V., Sudol, Marius, Brown, Peter J., Bunnage, Mark E., Owen, Dafydd R., Zaph, Colby, Vedadi, Masoud, Arrowsmith, Cheryl H.
المصدر: Proceedings of the National Academy of Sciences of the United States of America, 2014 Sep 01. 111(35), 12853-12858.
URL الوصول: https://www.jstor.org/stable/43043421
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المؤلفون: Eleanore Hendrickson, Martin James Wythes, Indrawan James Mcalpine, Karen A. Maegley, Christopher P. Dillon, Fen Wang, Kephart Susan Elizabeth, Amy Nemeth, Prakash B. Palde, Manli Shi, Kristen Jensen-Pergakes, Shinji Yamazaki, Tao Xie, Chi-Yeh Chung, Michelle Tran-Dubé, Tatlock John H, Stephanie Scales, Hieu Lam, Eugene Rui, Thomas A Paul, Elizabeth A. McMillan, Robert Arnold Kumpf, Ryan L. Patman, Michele McTigue, Natalie Miller, Ya-Li Deng, Yuli Wang, Noah Spiegel, Alexei Brooun, John Sherrill, Wei Liu, John F. Braganza
المصدر: Cancer Research. 81:1160-1160
مصطلحات موضوعية: Antitumor activity, Cancer Research, Oncology, Chemistry, Protein arginine methyltransferase 5, RNA splicing, Cancer research, Drug resistance
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ffac773af19496024ab15b63ff654a26
https://doi.org/10.1158/1538-7445.am2021-1160 -
4كتاب إلكتروني
المؤلفون: Hou, Xinjun J.Aff3, Tatlock, John H.Aff3, Linton, M. AngelicaAff3, Kissinger, Charles R.Aff3, Pelletier, Laura A.Aff3, Showalter, Richard E.Aff3, Tempczyk, AnnaAff3, Villafranca, J. ErnestAff3
المساهمون: Gundertofte, Klaus, editorAff1, Jørgensen, Flemming Steen, editorAff2
المصدر: Molecular Modeling and Prediction of Bioactivity. :384-385
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5دورية أكاديمية
لا يتم عرض هذه النتيجة على الضيوف.
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المؤلفون: Dafydd R. Owen, Aiping Dong, Martin James Wythes, Steven Kennedy, Dalia Barsyte-Lovejoy, Matthieu Schapira, Hong Wu, Rajiah Aldrin Denny, Viacheslav V. Trush, Mihir D. Parikh, Agustin Casimiro-Garcia, Renato Ferreira de Freitas, Masoud Vedadi, Magdalena Swewczyk, Hong Zeng, Tatlock John H, Fengling Li, Alexandria P. Taylor, Robert Arnold Kumpf, Peter Brown, Cheryl H. Arrowsmith
المصدر: Journal of medicinal chemistry. 62(17)
مصطلحات موضوعية: Models, Molecular, S-Adenosylmethionine, Methyltransferase, Lysine, 01 natural sciences, Small Molecule Libraries, 03 medical and health sciences, Structure-Activity Relationship, Drug Discovery, Structure–activity relationship, Humans, Binding site, Enzyme Inhibitors, Enhancer, Cells, Cultured, 030304 developmental biology, Cell Proliferation, chemistry.chemical_classification, 0303 health sciences, Binding Sites, Dose-Response Relationship, Drug, Molecular Structure, Substrate (chemistry), Histone-Lysine N-Methyltransferase, Small molecule, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Enzyme, chemistry, Biochemistry, Molecular Medicine
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المؤلفون: Tao Xie, Paulina Delgado Cuenca, Brion W. Murray, Keith A. Ching, Tatlock John H, Sherry Niessen, Patrick J. Metz, Kristen Jensen-Pergakes
المصدر: Cell Reports, Vol 30, Iss 6, Pp 1935-1950.e8 (2020)
مصطلحات موضوعية: 0301 basic medicine, Spliceosome, Arginine, RNA Splicing, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, 0302 clinical medicine, Interferon, medicine, Humans, lcsh:QH301-705.5, Messenger RNA, Chemistry, Protein arginine methyltransferase 5, Alternative splicing, Cell biology, Alternative Splicing, 030104 developmental biology, lcsh:Biology (General), RNA splicing, Interferons, Signal transduction, 030217 neurology & neurosurgery, Signal Transduction, medicine.drug
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المؤلفون: Robert Steven Kania, Eric Johnson, Tatlock John H, Luping Qiu, Timothy L. Foley, Shaoxian Sun, Kymberly Levine, Ketan S. Gajiwala, Ciarán N. Cronin, Michelle Kraus, Asako Nagata
المصدر: PLoS ONE
PLoS ONE, Vol 13, Iss 6, p e0198374 (2018)مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, Carcinogenesis, Kinase Inhibitors, Cell Membranes, Cancer Treatment, lcsh:Medicine, medicine.disease_cause, Crystallography, X-Ray, Biochemistry, chemistry.chemical_compound, 0302 clinical medicine, Breast Tumors, Medicine and Health Sciences, Chemical Precipitation, Enzyme Inhibitors, Phosphorylation, lcsh:Science, Multidisciplinary, Crystallography, Kinase, Physics, Chemical Reactions, Protein-Tyrosine Kinases, Condensed Matter Physics, Neoplasm Proteins, Gene Expression Regulation, Neoplastic, Chemistry, Oncology, 030220 oncology & carcinogenesis, Physical Sciences, Crystal Structure, Female, PTK6, Growth inhibition, Cellular Structures and Organelles, Crystallization, Tyrosine kinase, Research Article, Cell Survival, Breast Neoplasms, Small Molecule Libraries, 03 medical and health sciences, Structure-Activity Relationship, Cell Line, Tumor, Breast Cancer, medicine, Solid State Physics, Humans, Kinase activity, Cell Proliferation, Oncogene, Cell growth, lcsh:R, Biology and Life Sciences, Cancers and Neoplasms, Cell Biology, 030104 developmental biology, HEK293 Cells, chemistry, Cancer research, Enzymology, lcsh:Q
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المؤلفون: Patrick Bingham, Wade Diehl, Karen A. Maegley, Cody Krivacic, Buwen Huang, Zehnder Luke Raymond, Xiu Yu, Pei-Pei Kung, Tatlock John H, Ketan S. Gajiwala
المصدر: Bioorganic & Medicinal Chemistry Letters. 25:1532-1537
مصطلحات موضوعية: Models, Molecular, Methyltransferase, Clinical Biochemistry, Lysine, Pharmaceutical Science, macromolecular substances, Biochemistry, Structure-Activity Relationship, Drug Discovery, Humans, Enhancer of Zeste Homolog 2 Protein, Molecular Biology, IC50, Dose-Response Relationship, Drug, Molecular Structure, Chemistry, Organic Chemistry, EZH2, Polycomb Repressive Complex 2, Methylation, S-Adenosylhomocysteine, Molecular biology, Lipophilic efficiency, Drug Design, Histone methyltransferase, Molecular Medicine, Nucleoside
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المؤلفون: Abdellah Allali-Hassani, Marius Sudol, Amber L. Couzens, Menno J. Oudhoff, Hong Zeng, Peter Brown, Masoud Vedadi, Mitchell J.S. Braam, Aiping Dong, Anne-Claude Gingras, Brian S. Gerstenberger, Fengling Li, Richard Marcellus, Spencer A. Freeman, Fabio M.V. Rossi, Dafydd R. Owen, Rima Al-awar, Lee R. Roberts, Tatlock John H, Hong Wu, Paul V. Fish, Steven Kennedy, Ahmed Aman, Colby Zaph, Guillermo A. Senisterra, Matthieu Schapira, Jean-Philippe Lambert, Ekaterina Kuznetsova, Cheryl H. Arrowsmith, Mark E. Bunnage, Rachel L. Grimley, Dalia Barsyte-Lovejoy, Caroline L. Benn
المصدر: Proceedings of the National Academy of Sciences. 111:12853-12858
مصطلحات موضوعية: Pyrrolidines, Methyltransferase, Peptide binding, Protein Serine-Threonine Kinases, Biology, Epigenesis, Genetic, Structure-Activity Relationship, Tetrahydroisoquinolines, Humans, Structure–activity relationship, Hippo Signaling Pathway, Chemoproteomics, Enzyme Inhibitors, Adaptor Proteins, Signal Transducing, Sulfonamides, Hippo signaling pathway, Multidisciplinary, Dose-Response Relationship, Drug, Signal transducing adaptor protein, YAP-Signaling Proteins, Histone-Lysine N-Methyltransferase, Methyltransferases, Methylation, Biological Sciences, Fibroblasts, Phosphoproteins, Molecular biology, Protein Structure, Tertiary, Mutation, MCF-7 Cells, Signal transduction, Signal Transduction, Transcription Factors
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d23770c64651903f028988e2aa7651df
https://doi.org/10.1073/pnas.1407358111