-
1
المؤلفون: Christopher N. Johnson, Paul N. Mortenson, Tatsuya Urushima, Iwan J. P. de Esch, Yuji Ochi, Daniel A. Erlanson, Wolfgang Jahnke
المساهمون: Chemistry and Pharmaceutical Sciences, AIMMS
المصدر: Jahnke, W, Erlanson, D A, De Esch, I J P, Johnson, C N, Mortenson, P N, Ochi, Y & Urushima, T 2020, ' Fragment-to-Lead Medicinal Chemistry Publications in 2019 ', Journal of medicinal chemistry, vol. 63, no. 24, pp. 15494-15507 . https://doi.org/10.1021/acs.jmedchem.0c01608
Journal of medicinal chemistry, 63(24), 15494-15507. American Chemical Societyمصطلحات موضوعية: Library design, Chemistry, Drug discovery, Protein Stability, Chemistry, Pharmaceutical, Publications, Proteins, Data science, Lead (geology), Protein stability, Fragment (logic), Proteins metabolism, Drug Discovery, Screening method, Molecular Medicine, Humans, Protein Interaction Domains and Motifs
وصف الملف: application/pdf
-
2
المصدر: Biochemical Society transactions. 48(1)
مصطلحات موضوعية: Library design, 0303 health sciences, Screening techniques, Magnetic Resonance Spectroscopy, Drug discovery, Computer science, Drug Evaluation, Preclinical, 010402 general chemistry, Crystallography, X-Ray, 01 natural sciences, Biochemistry, Data science, 0104 chemical sciences, High-Throughput Screening Assays, Food and drug administration, Small Molecule Libraries, 03 medical and health sciences, Fragment (logic), Drug Design, Drug Discovery, Humans, Drug Approval, 030304 developmental biology, Protein Binding
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::434c314271c7cedbad5afb7c19f8646a
https://pubmed.ncbi.nlm.nih.gov/31985743 -
3
المؤلفون: Amir Rafiq, Wolfgang Kummer, Matthias Schönberger, Laura Laprell, Arunas Damijonaitis, Tatsuya Urushima, Alexander Gottschalk, Dirk Trauner, Johannes Broichhagen, Katharina Hüll, David H. Woodmansee, Jatin Nagpal, Martin Sumser
المصدر: ACS Chemical Neuroscience. 6:701-707
مصطلحات موضوعية: Male, Agonist, Patch-Clamp Techniques, alpha7 Nicotinic Acetylcholine Receptor, Physiology, medicine.drug_class, Cognitive Neuroscience, Biology, Transfection, 01 natural sciences, Biochemistry, Mice, 03 medical and health sciences, Slice preparation, Dorsal root ganglion, medicine, Animals, Humans, Nicotinic Agonists, Rats, Wistar, Caenorhabditis elegans, 030304 developmental biology, Acetylcholine receptor, 0303 health sciences, 010405 organic chemistry, Cell Biology, General Medicine, Ligand (biochemistry), Rats, 3. Good health, 0104 chemical sciences, Mice, Inbred C57BL, Quaternary Ammonium Compounds, Nicotinic acetylcholine receptor, HEK293 Cells, medicine.anatomical_structure, Nicotinic agonist, nervous system, Cholinergic, Female, sense organs, Nerve Net, Azo Compounds, Neuroscience
-
4دورية أكاديمية
المصدر: Biochemical Society Transactions; Feb2020, Vol. 48 Issue 1, p271-280, 10p
مصطلحات موضوعية: INDUSTRIAL chemistry
-
5
المؤلفون: Yujiro Hayashi, Kou Torii, Daisuke Sakamoto, Hayato Ishikawa, Tatsuya Urushima
المصدر: Chemistry - A European Journal. 17:11715-11718
مصطلحات موضوعية: Organic Chemistry, Imine, One-pot synthesis, General Chemistry, Medicinal chemistry, Catalysis, chemistry.chemical_compound, chemistry, Cascade reaction, Tosyl, One pot reaction, Organocatalysis, Chloroacetaldehyde, Organic chemistry, Mannich reaction
-
6
المؤلفون: Yujiro Hayashi, Hayato Ishikawa, Bojan P. Bondzic, Tatsuya Urushima
المصدر: Organic Letters. 12:5434-5437
مصطلحات موضوعية: chemistry.chemical_classification, Diphenylprolinol, Organic Chemistry, Ether, Biochemistry, Aldehyde, Catalysis, chemistry.chemical_compound, chemistry, Diphenylprolinol silyl ether, medicine, Organic chemistry, Physical and Theoretical Chemistry, Hydrogen peroxide, medicine.drug, Quaternary carbon
-
7
المؤلفون: Tatsuya Urushima, Yujiro Hayashi, Hayato Ishikawa, Yusuke Yasui
المصدر: Organic Letters. 12:2966-2969
مصطلحات موضوعية: Pyrrolidines, Molecular Structure, Polymers, Chemistry, Organic Chemistry, Enantioselective synthesis, Glyoxylate cycle, Glyoxylates, Stereoisomerism, Biochemistry, Catalysis, Aldol reaction, Alcohols, Yield (chemistry), Organic chemistry, Physical and Theoretical Chemistry
-
8
المؤلفون: Tatsuya Urushima, Takahiko Itoh, Hayato Ishikawa, Tsubasa Okano, Yujiro Hayashi, Tadafumi Uchimaru
المصدر: Angewandte Chemie International Edition. 47:9053-9058
مصطلحات موضوعية: chemistry.chemical_compound, chemistry, Organocatalysis, Imine, Acetaldehyde, Enantioselective synthesis, Organic chemistry, General Medicine, General Chemistry, Mannich reaction, Catalysis
-
9
المؤلفون: Mitsuru Shoji, Tatsuya Urushima, Wataru Tsuboi, Yujiro Hayashi
المصدر: Nature Protocols. 2:113-118
مصطلحات موضوعية: chemistry.chemical_classification, Aldehydes, Addition reaction, Aniline Compounds, Nitroaldol reaction, Molecular Structure, Proline, Imine, Enantioselective synthesis, Amino Alcohols, Aldehyde, Chemistry Techniques, Analytical, General Biochemistry, Genetics and Molecular Biology, Enamine, Mannich Bases, chemistry.chemical_compound, chemistry, Yield (chemistry), Organic chemistry, Amines, Mannich reaction
-
10
المؤلفون: Yujiro Hayashi, Tatsunobu Sumiya, Junichi Takahashi, Mitsuru Shoji, Hiroaki Gotoh, Tatsuya Urushima
المصدر: Angewandte Chemie. 118:972-975
مصطلحات موضوعية: Hajos–Parrish–Eder–Sauer–Wiechert reaction, Aldol reaction, Chemistry, Organocatalysis, Enantioselective synthesis, Organic chemistry, General Chemistry, General Medicine, Solvent effects, Catalysis
Find this issue from the American Chemical Society