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المؤلفون: Kumar S; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Department of Immunology, Harvard Medical School, Boston, Massachusetts., Zeng Z; Department of Data Sciences, Dana-Farber Cancer Institute, Harvard T. H. Chan School of Public Health, Boston, Massachusetts., Bagati A; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Department of Immunology, Harvard Medical School, Boston, Massachusetts., Tay RE; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Department of Immunology, Harvard Medical School, Boston, Massachusetts., Sanz LA; Department of Molecular and Cellular Biology and Genome Center, University of California, Davis, California., Hartono SR; Department of Molecular and Cellular Biology and Genome Center, University of California, Davis, California., Ito Y; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Department of Immunology, Harvard Medical School, Boston, Massachusetts., Abderazzaq F; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Harvard Medical School, Boston, Massachusetts., Hatchi E; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Harvard Medical School, Boston, Massachusetts., Jiang P; Department of Data Sciences, Dana-Farber Cancer Institute, Harvard T. H. Chan School of Public Health, Boston, Massachusetts.; Center for Cancer Research, National Cancer Institute, Bethesda, Maryland., Cartwright ANR; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Department of Immunology, Harvard Medical School, Boston, Massachusetts., Olawoyin O; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Yale School of Medicine, New Haven, Connecticut., Mathewson ND; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Department of Immunology, Harvard Medical School, Boston, Massachusetts., Pyrdol JW; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Department of Immunology, Harvard Medical School, Boston, Massachusetts., Li MZ; Department of Genetics, Harvard Medical School and Division of Genetics, Department of Medicine, Howard Hughes Medical Institute, Brigham and Women's Hospital, Boston, Massachusetts., Doench JG; Broad Institute of Harvard and MIT, Cambridge, Massachusetts., Booker MA; Department of Informatics and Analytics, Dana-Farber Cancer Institute, Boston, Massachusetts., Tolstorukov MY; Department of Informatics and Analytics, Dana-Farber Cancer Institute, Boston, Massachusetts., Elledge SJ; Department of Genetics, Harvard Medical School and Division of Genetics, Department of Medicine, Howard Hughes Medical Institute, Brigham and Women's Hospital, Boston, Massachusetts., Chédin F; Department of Molecular and Cellular Biology and Genome Center, University of California, Davis, California., Liu XS; Department of Data Sciences, Dana-Farber Cancer Institute, Harvard T. H. Chan School of Public Health, Boston, Massachusetts. kai_wucherpfennig@dfci.harvard.edu xsliu@ds.dfci.harvard.edu., Wucherpfennig KW; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, Massachusetts. kai_wucherpfennig@dfci.harvard.edu xsliu@ds.dfci.harvard.edu.; Department of Immunology, Harvard Medical School, Boston, Massachusetts.; Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.

المصدر: Cancer discovery [Cancer Discov] 2021 Aug; Vol. 11 (8), pp. 2050-2071. Date of Electronic Publication: 2021 Mar 11.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101561693 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2159-8290 (Electronic) Linking ISSN: 21598274 NLM ISO Abbreviation: Cancer Discov Subsets: MEDLINE

مواضيع طبية MeSH: Immune Checkpoint Inhibitors/*pharmacology , Neoplasms/*therapy , Protein-Arginine N-Methyltransferases/*antagonists & inhibitors, Cell Line, Tumor/drug effects ; Humans ; Immunotherapy ; T-Lymphocytes/drug effects

المؤلفون: Amoozgar Z; Edwin L. Steele Laboratories, Department of Radiation Oncology, Massachusetts General Hospital (MGH) and Harvard Medical School (HMS), Boston, MA, USA., Kloepper J; Edwin L. Steele Laboratories, Department of Radiation Oncology, Massachusetts General Hospital (MGH) and Harvard Medical School (HMS), Boston, MA, USA., Ren J; Edwin L. Steele Laboratories, Department of Radiation Oncology, Massachusetts General Hospital (MGH) and Harvard Medical School (HMS), Boston, MA, USA., Tay RE; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute (DFCI) and Harvard Medical School, Boston, MA, USA., Kazer SW; Department of Chemistry, Institute for Medical Engineering & Science, and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT), Cambridge, MA, USA.; Broad Institute of MIT and Harvard University, Cambridge, MA, USA.; Ragon Institute of MGH, MIT & Harvard, Cambridge, MA, USA.; Program in Health Sciences and Technology, Harvard Medical School, Boston, MA, USA., Kiner E; Department of Immunology, Harvard Medical School, Boston, MA, USA., Krishnan S; Edwin L. Steele Laboratories, Department of Radiation Oncology, Massachusetts General Hospital (MGH) and Harvard Medical School (HMS), Boston, MA, USA., Posada JM; Edwin L. Steele Laboratories, Department of Radiation Oncology, Massachusetts General Hospital (MGH) and Harvard Medical School (HMS), Boston, MA, USA., Ghosh M; Edwin L. Steele Laboratories, Department of Radiation Oncology, Massachusetts General Hospital (MGH) and Harvard Medical School (HMS), Boston, MA, USA., Mamessier E; Edwin L. Steele Laboratories, Department of Radiation Oncology, Massachusetts General Hospital (MGH) and Harvard Medical School (HMS), Boston, MA, USA., Wong C; Edwin L. Steele Laboratories, Department of Radiation Oncology, Massachusetts General Hospital (MGH) and Harvard Medical School (HMS), Boston, MA, USA., Ferraro GB; Edwin L. Steele Laboratories, Department of Radiation Oncology, Massachusetts General Hospital (MGH) and Harvard Medical School (HMS), Boston, MA, USA., Batista A; Edwin L. Steele Laboratories, Department of Radiation Oncology, Massachusetts General Hospital (MGH) and Harvard Medical School (HMS), Boston, MA, USA., Wang N; Edwin L. Steele Laboratories, Department of Radiation Oncology, Massachusetts General Hospital (MGH) and Harvard Medical School (HMS), Boston, MA, USA., Badeaux M; Edwin L. Steele Laboratories, Department of Radiation Oncology, Massachusetts General Hospital (MGH) and Harvard Medical School (HMS), Boston, MA, USA., Roberge S; Edwin L. Steele Laboratories, Department of Radiation Oncology, Massachusetts General Hospital (MGH) and Harvard Medical School (HMS), Boston, MA, USA., Xu L; Edwin L. Steele Laboratories, Department of Radiation Oncology, Massachusetts General Hospital (MGH) and Harvard Medical School (HMS), Boston, MA, USA., Huang P; Edwin L. Steele Laboratories, Department of Radiation Oncology, Massachusetts General Hospital (MGH) and Harvard Medical School (HMS), Boston, MA, USA., Shalek AK; Department of Chemistry, Institute for Medical Engineering & Science, and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT), Cambridge, MA, USA.; Broad Institute of MIT and Harvard University, Cambridge, MA, USA.; Ragon Institute of MGH, MIT & Harvard, Cambridge, MA, USA.; Program in Health Sciences and Technology, Harvard Medical School, Boston, MA, USA., Fukumura D; Edwin L. Steele Laboratories, Department of Radiation Oncology, Massachusetts General Hospital (MGH) and Harvard Medical School (HMS), Boston, MA, USA., Kim HJ; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute (DFCI) and Harvard Medical School, Boston, MA, USA. Jain@steele.mgh.harvard.edu., Jain RK; Edwin L. Steele Laboratories, Department of Radiation Oncology, Massachusetts General Hospital (MGH) and Harvard Medical School (HMS), Boston, MA, USA. Hye-Jung_kim@dfci.harvard.edu.

المصدر: Nature communications [Nat Commun] 2021 May 11; Vol. 12 (1), pp. 2582. Date of Electronic Publication: 2021 May 11.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Combined Chemotherapy Protocols/*pharmacology , Drug Resistance, Neoplasm/*drug effects , Glioblastoma/*drug therapy , Glucocorticoid-Induced TNFR-Related Protein/*agonists , T-Lymphocytes, Regulatory/*drug effects, Animals ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Cell Line, Tumor/transplantation ; Cellular Reprogramming/drug effects ; Cellular Reprogramming/immunology ; Disease Models, Animal ; Female ; Glioblastoma/immunology ; Humans ; Immune Checkpoint Inhibitors/pharmacology ; Immune Checkpoint Inhibitors/therapeutic use ; Immunologic Memory/drug effects ; Male ; Mice ; Mice, Knockout ; Programmed Cell Death 1 Receptor/antagonists & inhibitors ; T-Lymphocytes, Cytotoxic/immunology ; T-Lymphocytes, Regulatory/immunology ; T-Lymphocytes, Regulatory/metabolism

المؤلفون: Tay RE; Singapore Immunology Network, Agency for Science, Technology, and Research (A*STAR), Singapore, 138648, Singapore., Richardson EK; Division of Medical Oncology, National Cancer Centre Singapore, Singapore, 169610, Singapore., Toh HC; Singapore Immunology Network, Agency for Science, Technology, and Research (A*STAR), Singapore, 138648, Singapore. toh.han.chong@singhealth.com.sg.; Division of Medical Oncology, National Cancer Centre Singapore, Singapore, 169610, Singapore. toh.han.chong@singhealth.com.sg.

المصدر: Cancer gene therapy [Cancer Gene Ther] 2021 Feb; Vol. 28 (1-2), pp. 5-17. Date of Electronic Publication: 2020 May 27.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 9432230 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5500 (Electronic) Linking ISSN: 09291903 NLM ISO Abbreviation: Cancer Gene Ther Subsets: MEDLINE

مواضيع طبية MeSH: CD4-Positive T-Lymphocytes/*metabolism , Immunotherapy/*methods , Neoplasms/*immunology , T-Lymphocytes/*immunology, Humans

المؤلفون: Tay RE; Department of Immunology, Harvard Medical School, Boston, MA.; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA., Olawoyin O; Department of Immunology, Harvard Medical School, Boston, MA.; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA., Cejas P; Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, MA., Xie Y; Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, MA., Meyer CA; Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA., Ito Y, Weng QY; Cutaneous Biology Research Center, Department of Dermatology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA., Fisher DE; Cutaneous Biology Research Center, Department of Dermatology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA., Long HW; Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, MA., Brown M; Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, MA.; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA., Kim HJ; Department of Immunology, Harvard Medical School, Boston, MA.; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA., Wucherpfennig KW; Department of Immunology, Harvard Medical School, Boston, MA.; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA.

المصدر: The Journal of experimental medicine [J Exp Med] 2020 Jul 06; Vol. 217 (7).

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Rockefeller University Press Country of Publication: United States NLM ID: 2985109R Publication Model: Print Cited Medium: Internet ISSN: 1540-9538 (Electronic) Linking ISSN: 00221007 NLM ISO Abbreviation: J Exp Med Subsets: MEDLINE

مواضيع طبية MeSH: Epigenesis, Genetic*/drug effects , T-Lymphocytes, Cytotoxic*/drug effects, CD8-Positive T-Lymphocytes/*immunology , Histone Deacetylases/*metabolism, Acetylation/drug effects ; Acrylamides/pharmacology ; Animals ; Antigens/metabolism ; Base Sequence ; CD8-Positive T-Lymphocytes/drug effects ; Core Binding Factor Alpha 3 Subunit/metabolism ; Histone Deacetylase Inhibitors/pharmacology ; Histone Deacetylases/deficiency ; Histones/metabolism ; Lymph Nodes/drug effects ; Lymph Nodes/metabolism ; Lymphocyte Activation/drug effects ; Lymphocyte Activation/immunology ; Lymphocytic choriomeningitis virus/physiology ; Lysine/metabolism ; Mice, Inbred C57BL ; Mice, Knockout ; Phenotype ; Phenylenediamines/pharmacology ; Positive Regulatory Domain I-Binding Factor 1/metabolism ; Transcription, Genetic/drug effects

المؤلفون: Tay RE, Olawoyin O, Cejas P, Xie Y, Meyer CA, Ito Y, Weng QY, Fisher DE, Long HW, Brown M, Kim HJ, Wucherpfennig KW

المصدر: The Journal of experimental medicine [J Exp Med] 2020 Jul 06; Vol. 217 (7).

نوع المنشور: Journal Article; Published Erratum

بيانات الدورية: Publisher: Rockefeller University Press Country of Publication: United States NLM ID: 2985109R Publication Model: Print Cited Medium: Internet ISSN: 1540-9538 (Electronic) Linking ISSN: 00221007 NLM ISO Abbreviation: J Exp Med Subsets: PubMed not MEDLINE; MEDLINE

المؤلفون: Zhang Y; Department of Biological Sciences, National University of Singapore, 14 Science Drive 4, Singapore, 117543, Republic of Singapore. zhangyuchen@u.nus.edu., Prescott GW; Department of Biological Sciences, National University of Singapore, 14 Science Drive 4, Singapore, 117543, Republic of Singapore., Tay RE; Department of Biological Sciences, National University of Singapore, 14 Science Drive 4, Singapore, 117543, Republic of Singapore., Dickens BL; Department of Biological Sciences, National University of Singapore, 14 Science Drive 4, Singapore, 117543, Republic of Singapore., Webb EL; Department of Biological Sciences, National University of Singapore, 14 Science Drive 4, Singapore, 117543, Republic of Singapore., Htun S; Wildlife Conservation Society Myanmar Program, Aye Yeik Mon 1st Street, Ward 3, Building C1 Hlaing Township, 11051, Yangon, Myanmar., Tizard RJ; Wildlife Conservation Society Myanmar Program, Aye Yeik Mon 1st Street, Ward 3, Building C1 Hlaing Township, 11051, Yangon, Myanmar., Rao M; Department of Biological Sciences, National University of Singapore, 14 Science Drive 4, Singapore, 117543, Republic of Singapore.; Wildlife Conservation Society Asia Program, 2300 Southern Boulevard, Bronx, New York, New York, 10460, USA., Carrasco LR; Department of Biological Sciences, National University of Singapore, 14 Science Drive 4, Singapore, 117543, Republic of Singapore.

المصدر: Scientific reports [Sci Rep] 2018 Nov 08; Vol. 8 (1), pp. 16558. Date of Electronic Publication: 2018 Nov 08.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

مواضيع طبية MeSH: Conservation of Natural Resources*, Agriculture/*legislation & jurisprudence , Crops, Agricultural/*growth & development, Biodiversity ; Crops, Agricultural/classification ; Economic Development ; Forests ; Models, Theoretical ; Myanmar

المؤلفون: Ito Y; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA.; Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA., Ashenberg O; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA., Pyrdol J; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA., Luoma AM; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA.; Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA., Rozenblatt-Rosen O; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA., Hofree M; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA., Christian E; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA., Ferrari de Andrade L; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA.; Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA., Tay RE; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA.; Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA., Teyton L; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA., Regev A; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA., Dougan SK; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA stephanie_dougan@dfci.harvard.edu.; Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA., Wucherpfennig KW; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA kai_wucherpfennig@dfci.harvard.edu.; Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA.

المصدر: The Journal of experimental medicine [J Exp Med] 2018 Oct 01; Vol. 215 (10), pp. 2617-2635. Date of Electronic Publication: 2018 Sep 05.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Rockefeller University Press Country of Publication: United States NLM ID: 2985109R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1540-9538 (Electronic) Linking ISSN: 00221007 NLM ISO Abbreviation: J Exp Med Subsets: MEDLINE

مواضيع طبية MeSH: Antigen Presentation* , Autoimmunity*, Antigens, Differentiation, B-Lymphocyte/*immunology , CD4-Positive T-Lymphocytes/*immunology , Histocompatibility Antigens Class II/*immunology, Animals ; Antigens, Differentiation, B-Lymphocyte/genetics ; CD4-Positive T-Lymphocytes/cytology ; Gene Knock-In Techniques ; Histocompatibility Antigens Class II/genetics ; Mice ; Mice, Inbred NOD ; Mice, Transgenic

المؤلفون: Ferrari de Andrade L; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02215, USA.; Harvard Medical School, 25 Shattuck Street, Boston, MA 02115, USA., Tay RE; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02215, USA.; Harvard Medical School, 25 Shattuck Street, Boston, MA 02115, USA., Pan D; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02215, USA.; Harvard Medical School, 25 Shattuck Street, Boston, MA 02115, USA., Luoma AM; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02215, USA.; Harvard Medical School, 25 Shattuck Street, Boston, MA 02115, USA., Ito Y; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02215, USA.; Harvard Medical School, 25 Shattuck Street, Boston, MA 02115, USA., Badrinath S; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02215, USA.; Harvard Medical School, 25 Shattuck Street, Boston, MA 02115, USA., Tsoucas D; Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02215, USA., Franz B; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02215, USA.; Harvard Medical School, 25 Shattuck Street, Boston, MA 02115, USA., May KF Jr; Department of Medical Oncology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02215, USA., Harvey CJ; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02215, USA., Kobold S; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02215, USA., Pyrdol JW; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02215, USA., Yoon C; Department of Medical Oncology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02215, USA.; Department of Surgery, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, USA., Yuan GC; Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02215, USA., Hodi FS; Department of Medical Oncology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02215, USA., Dranoff G; Department of Medical Oncology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02215, USA., Wucherpfennig KW; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02215, USA. kai_wucherpfennig@dfci.harvard.edu.; Harvard Medical School, 25 Shattuck Street, Boston, MA 02115, USA.

المصدر: Science (New York, N.Y.) [Science] 2018 Mar 30; Vol. 359 (6383), pp. 1537-1542.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE

مواضيع طبية MeSH: Antibodies, Blocking/*therapeutic use , Antibodies, Monoclonal/*therapeutic use , Histocompatibility Antigens Class I/*immunology , Killer Cells, Natural/*immunology , Melanoma/*therapy, Animals ; Antibodies, Blocking/immunology ; Antibodies, Monoclonal/immunology ; Histocompatibility Antigens Class I/chemistry ; Humans ; Immunocompetence ; Ligands ; Melanoma/immunology ; Melanoma/pathology ; Melanoma, Experimental/immunology ; Melanoma, Experimental/pathology ; Melanoma, Experimental/therapy ; Mice ; Mice, Inbred C57BL ; NK Cell Lectin-Like Receptor Subfamily K/immunology ; Neoplasm Metastasis ; Protein Domains/immunology ; Receptors, IgG/immunology

المؤلفون: Pan D; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Kobayashi A; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.; Astellas Pharma, Tokyo 103-8411, Japan., Jiang P; Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Ferrari de Andrade L; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Tay RE; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Luoma AM; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Tsoucas D; Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Qiu X; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Lim K; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Rao P; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Long HW; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Yuan GC; Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Doench J; Genetic Perturbation Platform, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Brown M; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Liu XS; Astellas Pharma, Tokyo 103-8411, Japan. kai_wucherpfennig@dfci.harvard.edu xsliu@jimmy.harvard.edu., Wucherpfennig KW; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA 02215, USA. kai_wucherpfennig@dfci.harvard.edu xsliu@jimmy.harvard.edu.; Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA 02115, USA.

المصدر: Science (New York, N.Y.) [Science] 2018 Feb 16; Vol. 359 (6377), pp. 770-775. Date of Electronic Publication: 2018 Jan 04.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE

مواضيع طبية MeSH: Chromosomal Proteins, Non-Histone/*metabolism , Cytotoxicity, Immunologic/*genetics , Melanoma, Experimental/*immunology , Melanoma, Experimental/*therapy , Skin Neoplasms/*immunology , Skin Neoplasms/*therapy , T-Lymphocytes, Cytotoxic/*immunology , Transcription Factors/*metabolism, Animals ; Bacterial Proteins ; CRISPR-Associated Protein 9 ; CRISPR-Cas Systems ; Cell Line, Tumor ; Chromosomal Proteins, Non-Histone/genetics ; DNA-Binding Proteins ; Endonucleases ; Genetic Testing ; HMGB Proteins/genetics ; HMGB Proteins/metabolism ; Humans ; Immunotherapy ; Interferon-gamma/therapeutic use ; Melanoma, Experimental/genetics ; Mice ; Skin Neoplasms/genetics ; Transcription Factors/genetics