المؤلفون: Teodoro JS; MitoLab, Department of Life Sciences, University of Coimbra, 3000 Coimbra, Portugal.; MitoLab, Mitochondria, Metabolism and Disease Group, Center for Neurosciences and Cell Biology, Faculdade de Medicina, University of Coimbra, 3000 Coimbra, Portugal.; IIIUC-Institute of Interdisciplinary Research, University of Coimbra, Pólo II da Universidade de Coimbra, 3000 Coimbra, Portugal., Da Silva RT; MitoLab, Mitochondria, Metabolism and Disease Group, Center for Neurosciences and Cell Biology, Faculdade de Medicina, University of Coimbra, 3000 Coimbra, Portugal.; Experimental Pathology Department, Institute of Biomedical Research of Barcelona (IIBB), CSIC-IDIBAPS, 08036 Barcelona, Spain., Machado IF; MitoLab, Mitochondria, Metabolism and Disease Group, Center for Neurosciences and Cell Biology, Faculdade de Medicina, University of Coimbra, 3000 Coimbra, Portugal.; IIIUC-Institute of Interdisciplinary Research, University of Coimbra, Pólo II da Universidade de Coimbra, 3000 Coimbra, Portugal., Panisello-Roselló A; Experimental Pathology Department, Institute of Biomedical Research of Barcelona (IIBB), CSIC-IDIBAPS, 08036 Barcelona, Spain., Roselló-Catafau J; Experimental Pathology Department, Institute of Biomedical Research of Barcelona (IIBB), CSIC-IDIBAPS, 08036 Barcelona, Spain., Rolo AP; MitoLab, Department of Life Sciences, University of Coimbra, 3000 Coimbra, Portugal.; MitoLab, Mitochondria, Metabolism and Disease Group, Center for Neurosciences and Cell Biology, Faculdade de Medicina, University of Coimbra, 3000 Coimbra, Portugal., Palmeira CM; MitoLab, Department of Life Sciences, University of Coimbra, 3000 Coimbra, Portugal.; MitoLab, Mitochondria, Metabolism and Disease Group, Center for Neurosciences and Cell Biology, Faculdade de Medicina, University of Coimbra, 3000 Coimbra, Portugal.

المصدر: Cells [Cells] 2022 Feb 16; Vol. 11 (4). Date of Electronic Publication: 2022 Feb 16.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Review

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409 (Electronic) Linking ISSN: 20734409 NLM ISO Abbreviation: Cells Subsets: MEDLINE

مواضيع طبية MeSH: Liver Diseases* , Reperfusion Injury*, Animals ; Disease Models, Animal ; Ischemia ; Mitochondria ; Reperfusion

المؤلفون: Teixeira da Silva R; Department of Life Sciences, University of Coimbra, 3000-456 Coimbra, Portugal.; Center for Neurosciences and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.; Experimental Pathology Department, Institute of Biomedical Research of Barcelona (IIBB), CSIC-IDIBAPS, 08036 Barcelona, Spain., Machado IF; Center for Neurosciences and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.; IIIUC-Institute of Interdisciplinary Research, University of Coimbra, 3030-789 Coimbra, Portugal., Teodoro JS; Department of Life Sciences, University of Coimbra, 3000-456 Coimbra, Portugal.; Center for Neurosciences and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal., Panisello-Roselló A; Experimental Pathology Department, Institute of Biomedical Research of Barcelona (IIBB), CSIC-IDIBAPS, 08036 Barcelona, Spain., Roselló-Catafau J; Experimental Pathology Department, Institute of Biomedical Research of Barcelona (IIBB), CSIC-IDIBAPS, 08036 Barcelona, Spain., Rolo AP; Department of Life Sciences, University of Coimbra, 3000-456 Coimbra, Portugal.; Center for Neurosciences and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal., Palmeira CM; Department of Life Sciences, University of Coimbra, 3000-456 Coimbra, Portugal.; Center for Neurosciences and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.

المصدر: International journal of molecular sciences [Int J Mol Sci] 2022 Jan 21; Vol. 23 (3). Date of Electronic Publication: 2022 Jan 21.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Hypoxia/*physiopathology , Ischemic Preconditioning/*methods , Liver/*drug effects , Mitochondria/*drug effects , Polyethylene Glycols/*pharmacology , Protective Agents/*pharmacology , Reperfusion Injury/*drug therapy, Autophagy ; Humans ; Liver/pathology ; Membrane Potential, Mitochondrial ; Mitochondria/metabolism ; Mitochondria/pathology ; Reperfusion Injury/etiology ; Reperfusion Injury/metabolism ; Reperfusion Injury/pathology

المؤلفون: Nunes S; Institute of Pharmacology & Experimental Therapeutics & Coimbra Institute for Clinical and Biomedical Research (iCBR), Faculty of Medicine, University of Coimbra, 3000-548 Coimbra, Portugal.; Center for Innovative Biomedicine and Biotechnology (CIBB), University of Coimbra, 3004-504 Coimbra, Portugal.; Clinical Academic Center of Coimbra (CACC), 3004-504 Coimbra, Portugal., Viana SD; Institute of Pharmacology & Experimental Therapeutics & Coimbra Institute for Clinical and Biomedical Research (iCBR), Faculty of Medicine, University of Coimbra, 3000-548 Coimbra, Portugal.; Center for Innovative Biomedicine and Biotechnology (CIBB), University of Coimbra, 3004-504 Coimbra, Portugal.; Clinical Academic Center of Coimbra (CACC), 3004-504 Coimbra, Portugal.; Polytechnic Institute of Coimbra, ESTESC-Coimbra Health School, Pharmacy/Biomedical Laboratory Sciences, 3046-854 Coimbra, Portugal., Preguiça I; Institute of Pharmacology & Experimental Therapeutics & Coimbra Institute for Clinical and Biomedical Research (iCBR), Faculty of Medicine, University of Coimbra, 3000-548 Coimbra, Portugal.; Center for Innovative Biomedicine and Biotechnology (CIBB), University of Coimbra, 3004-504 Coimbra, Portugal.; Clinical Academic Center of Coimbra (CACC), 3004-504 Coimbra, Portugal., Alves A; Institute of Pharmacology & Experimental Therapeutics & Coimbra Institute for Clinical and Biomedical Research (iCBR), Faculty of Medicine, University of Coimbra, 3000-548 Coimbra, Portugal.; Center for Innovative Biomedicine and Biotechnology (CIBB), University of Coimbra, 3004-504 Coimbra, Portugal.; Clinical Academic Center of Coimbra (CACC), 3004-504 Coimbra, Portugal., Fernandes R; Institute of Pharmacology & Experimental Therapeutics & Coimbra Institute for Clinical and Biomedical Research (iCBR), Faculty of Medicine, University of Coimbra, 3000-548 Coimbra, Portugal.; Center for Innovative Biomedicine and Biotechnology (CIBB), University of Coimbra, 3004-504 Coimbra, Portugal.; Clinical Academic Center of Coimbra (CACC), 3004-504 Coimbra, Portugal., Teodoro JS; Department of Life Sciences, Faculty of Science and Technology (FCTUC), University of Coimbra, 3000-456 Coimbra, Portugal.; Center for Neurosciences and Cell Biology of Coimbra (CNC), University of Coimbra, 3004-504 Coimbra, Portugal., Matos P; Faculty of Pharmacy, University of Coimbra, 3000-548 Coimbra, Portugal.; LAQV, REQUIMTE, Faculty of Pharmacy, University of Coimbra, 3000-456 Coimbra, Portugal.; CIEPQPF, Chemical Process Engineering and Forest Products Research Centre Research Center, University of Coimbra, 3000-456 Coimbra, Portugal., Figueirinha A; Faculty of Pharmacy, University of Coimbra, 3000-548 Coimbra, Portugal.; LAQV, REQUIMTE, Faculty of Pharmacy, University of Coimbra, 3000-456 Coimbra, Portugal., Salgueiro L; Faculty of Pharmacy, University of Coimbra, 3000-548 Coimbra, Portugal.; CIEPQPF, Chemical Process Engineering and Forest Products Research Centre Research Center, University of Coimbra, 3000-456 Coimbra, Portugal., André A; Polytechnic Institute of Coimbra, ESTESC-Coimbra Health School, Pharmacy/Biomedical Laboratory Sciences, 3046-854 Coimbra, Portugal., Silva S; CBQF-Centro de Biotecnologia e Química Fina-Laboratório Associado, Escola Superior de Biotecnologia, Universidade Católica Portuguesa, Rua Diogo Botelho 1327, 4169-005 Porto, Portugal., Jarak I; Department of Microscopy, Laboratory of Cell Biology and Unit for Multidisciplinary Research in Biomedicine (UMIB), Institute of Biomedical Sciences Abel Salazar (ICBAS), University of Porto, 4050-313 Porto, Portugal., Carvalho RA; Department of Life Sciences, Faculty of Science and Technology (FCTUC), University of Coimbra, 3000-456 Coimbra, Portugal.; Associated Laboratory for Green Chemistry-Clean Technologies and Processes, REQUIMTE, Faculty of Sciences and Technology, University of Porto, 4050-313 Porto, Portugal., Cavadas C; Center for Innovative Biomedicine and Biotechnology (CIBB), University of Coimbra, 3004-504 Coimbra, Portugal.; Clinical Academic Center of Coimbra (CACC), 3004-504 Coimbra, Portugal.; Center for Neurosciences and Cell Biology of Coimbra (CNC), University of Coimbra, 3004-504 Coimbra, Portugal.; Faculty of Pharmacy, University of Coimbra, 3000-548 Coimbra, Portugal., Rolo AP; Department of Life Sciences, Faculty of Science and Technology (FCTUC), University of Coimbra, 3000-456 Coimbra, Portugal.; Center for Neurosciences and Cell Biology of Coimbra (CNC), University of Coimbra, 3004-504 Coimbra, Portugal., Palmeira CM; Department of Life Sciences, Faculty of Science and Technology (FCTUC), University of Coimbra, 3000-456 Coimbra, Portugal.; Center for Neurosciences and Cell Biology of Coimbra (CNC), University of Coimbra, 3004-504 Coimbra, Portugal., Pintado MM; CBQF-Centro de Biotecnologia e Química Fina-Laboratório Associado, Escola Superior de Biotecnologia, Universidade Católica Portuguesa, Rua Diogo Botelho 1327, 4169-005 Porto, Portugal., Reis F; Institute of Pharmacology & Experimental Therapeutics & Coimbra Institute for Clinical and Biomedical Research (iCBR), Faculty of Medicine, University of Coimbra, 3000-548 Coimbra, Portugal.; Center for Innovative Biomedicine and Biotechnology (CIBB), University of Coimbra, 3004-504 Coimbra, Portugal.; Clinical Academic Center of Coimbra (CACC), 3004-504 Coimbra, Portugal.

المصدر: Nutrients [Nutrients] 2021 Nov 23; Vol. 13 (12). Date of Electronic Publication: 2021 Nov 23.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Publishing Country of Publication: Switzerland NLM ID: 101521595 Publication Model: Electronic Cited Medium: Internet ISSN: 2072-6643 (Electronic) Linking ISSN: 20726643 NLM ISO Abbreviation: Nutrients Subsets: MEDLINE

مواضيع طبية MeSH: Blueberry Plants* , Fruit and Vegetable Juices*, Diabetes Mellitus, Type 2/*metabolism , Energy Intake/*drug effects , Prediabetic State/*metabolism, Animals ; Blood Glucose/drug effects ; Diabetes Mellitus, Type 2/prevention & control ; Disease Models, Animal ; Energy Metabolism/drug effects ; Gastrointestinal Microbiome/drug effects ; Insulin/blood ; Insulin Resistance ; Lipid Metabolism/drug effects ; Lipids/blood ; Liver/metabolism ; Mitochondria/metabolism ; Rats

المؤلفون: Teodoro JS; Department of Life Sciences, University of Coimbra, Calçada Martim de Freitas, 3000 Coimbra, Portugal.; Center for Neurosciences and Cell Biology, Rua Larga, Faculdade de Medicina, University of Coimbra, 3000 Coimbra, Portugal., Machado IF; Department of Life Sciences, University of Coimbra, Calçada Martim de Freitas, 3000 Coimbra, Portugal.; Center for Neurosciences and Cell Biology, Rua Larga, Faculdade de Medicina, University of Coimbra, 3000 Coimbra, Portugal., Castela AC; Department of Life Sciences, University of Coimbra, Calçada Martim de Freitas, 3000 Coimbra, Portugal., Amorim JA; Center for Neurosciences and Cell Biology, Rua Larga, Faculdade de Medicina, University of Coimbra, 3000 Coimbra, Portugal.; IIIUC-Institute of Interdisciplinary Research, University of Coimbra, Pólo II da Universidade de Coimbra, 3000 Coimbra, Portugal.; Department of Genetics, Blavatnik Institute, Paul F. Glenn Center for the Biology of Aging, Harvard Medical School, Boston, MA 02115, USA., Jarak I; Department of Pharmaceutical Technology, Faculty of Pharmacy of the University of Coimbra, Azinhaga de Santa Comba, Pólo das Ciências da Saúde, 3000 Coimbra, Portugal., Carvalho RA; Department of Life Sciences, University of Coimbra, Calçada Martim de Freitas, 3000 Coimbra, Portugal., Palmeira CM; Department of Life Sciences, University of Coimbra, Calçada Martim de Freitas, 3000 Coimbra, Portugal.; Center for Neurosciences and Cell Biology, Rua Larga, Faculdade de Medicina, University of Coimbra, 3000 Coimbra, Portugal., Rolo AP; Department of Life Sciences, University of Coimbra, Calçada Martim de Freitas, 3000 Coimbra, Portugal.; Center for Neurosciences and Cell Biology, Rua Larga, Faculdade de Medicina, University of Coimbra, 3000 Coimbra, Portugal.

المصدر: International journal of molecular sciences [Int J Mol Sci] 2021 Oct 29; Vol. 22 (21). Date of Electronic Publication: 2021 Oct 29.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

مواضيع طبية MeSH: CRISPR-Cas Systems*, Anti-Obesity Agents/*pharmacology , Chenodeoxycholic Acid/*pharmacology , Mitochondria/*metabolism , Obesity/*drug therapy , Receptors, G-Protein-Coupled/*deficiency, 3T3-L1 Cells ; Animals ; Gene Knockdown Techniques ; Mice ; Mitochondria/genetics ; Obesity/genetics ; Obesity/metabolism ; Receptors, G-Protein-Coupled/metabolism ; Thermogenesis/drug effects ; Thermogenesis/genetics

المؤلفون: Machado IF; Department of Life Sciences, Faculty of Sciences and Technology, University of Coimbra, 3000-456 Coimbra, Portugal.; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal., Teodoro JS; Department of Life Sciences, Faculty of Sciences and Technology, University of Coimbra, 3000-456 Coimbra, Portugal.; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal., Castela AC; Department of Life Sciences, Faculty of Sciences and Technology, University of Coimbra, 3000-456 Coimbra, Portugal.; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal., Palmeira CM; Department of Life Sciences, Faculty of Sciences and Technology, University of Coimbra, 3000-456 Coimbra, Portugal.; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal., Rolo AP; Department of Life Sciences, Faculty of Sciences and Technology, University of Coimbra, 3000-456 Coimbra, Portugal.; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.

المصدر: International journal of molecular sciences [Int J Mol Sci] 2021 Jan 07; Vol. 22 (2). Date of Electronic Publication: 2021 Jan 07.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Diabetes Mellitus, Type 2/*drug therapy , Hyperglycemia/*drug therapy , Metformin/*pharmacology , MicroRNAs/*genetics , Nuclear Proteins/*genetics, Adenosine Triphosphate/metabolism ; Animals ; Apoptosis/drug effects ; Autophagy/drug effects ; Cell Proliferation/drug effects ; Diabetes Mellitus, Type 2/genetics ; Diabetes Mellitus, Type 2/pathology ; Gene Expression Regulation/drug effects ; Humans ; Hyperglycemia/genetics ; Hyperglycemia/pathology ; Mice

المؤلفون: Teodoro JS; MitoLab, Department of Life Sciences, Center for Neurosciences and Cell Biology of the University of Coimbra, Coimbra, Portugal., Rolo AP; MitoLab, Department of Life Sciences, Center for Neurosciences and Cell Biology of the University of Coimbra, Coimbra, Portugal., Palmeira CMM; MitoLab, Department of Life Sciences, Center for Neurosciences and Cell Biology of the University of Coimbra, Coimbra, Portugal. palmeira@uc.pt.

المصدر: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2021; Vol. 2240, pp. 231-241.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Humana Press Country of Publication: United States NLM ID: 9214969 Publication Model: Print Cited Medium: Internet ISSN: 1940-6029 (Electronic) Linking ISSN: 10643745 NLM ISO Abbreviation: Methods Mol Biol Subsets: MEDLINE

مواضيع طبية MeSH: Biological Assay* , Toxicity Tests*, Energy Metabolism/*drug effects , Mitochondria, Liver/*drug effects, Animals ; Calcium/metabolism ; Membrane Potential, Mitochondrial/drug effects ; Mitochondria, Liver/metabolism ; Mitochondria, Liver/pathology ; Mitochondrial Swelling/drug effects ; Oxygen Consumption/drug effects ; Rats

المؤلفون: Teodoro JS; Department of Life Sciences and Center for Neurosciences and Cell Biology, University of Coimbra, Coimbra, Portugal., Machado IF; Department of Life Sciences and Center for Neurosciences and Cell Biology, University of Coimbra, Coimbra, Portugal., Palmeira CM; Department of Life Sciences and Center for Neurosciences and Cell Biology, University of Coimbra, Coimbra, Portugal., Rolo AP; Department of Life Sciences and Center for Neurosciences and Cell Biology, University of Coimbra, Coimbra, Portugal. anpiro@ci.uc.pt.

المصدر: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2021; Vol. 2310, pp. 17-31.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Humana Press Country of Publication: United States NLM ID: 9214969 Publication Model: Print Cited Medium: Internet ISSN: 1940-6029 (Electronic) Linking ISSN: 10643745 NLM ISO Abbreviation: Methods Mol Biol Subsets: MEDLINE

مواضيع طبية MeSH: Oxidative Phosphorylation*, Electron Transport Chain Complex Proteins/*metabolism , Mitochondria, Liver/*enzymology , Mitochondrial Proteins/*metabolism, Animals ; Cell Fractionation ; Centrifugation ; Mice ; Rats

المؤلفون: Nunes S; Institute of Pharmacology & Experimental Therapeutics & Coimbra Institute for Clinical and Biomedical Research (iCBR), Faculty of Medicine, University of Coimbra, 3000-548 Coimbra, Portugal.; Center for Innovative Biomedicine and Biotechnology (CIBB), University of Coimbra, 3004-504 Coimbra, Portugal.; Clinical Academic Center of Coimbra (CACC), 3004-504 Coimbra, Portugal., Viana SD; Institute of Pharmacology & Experimental Therapeutics & Coimbra Institute for Clinical and Biomedical Research (iCBR), Faculty of Medicine, University of Coimbra, 3000-548 Coimbra, Portugal.; Center for Innovative Biomedicine and Biotechnology (CIBB), University of Coimbra, 3004-504 Coimbra, Portugal.; Clinical Academic Center of Coimbra (CACC), 3004-504 Coimbra, Portugal.; Polytechnic Institute of Coimbra, ESTESC-Coimbra Health School, Pharmacy/Biomedical Laboratory Sciences, 3046-854 Coimbra, Portugal., Preguiça I; Institute of Pharmacology & Experimental Therapeutics & Coimbra Institute for Clinical and Biomedical Research (iCBR), Faculty of Medicine, University of Coimbra, 3000-548 Coimbra, Portugal.; Center for Innovative Biomedicine and Biotechnology (CIBB), University of Coimbra, 3004-504 Coimbra, Portugal.; Clinical Academic Center of Coimbra (CACC), 3004-504 Coimbra, Portugal., Alves A; Institute of Pharmacology & Experimental Therapeutics & Coimbra Institute for Clinical and Biomedical Research (iCBR), Faculty of Medicine, University of Coimbra, 3000-548 Coimbra, Portugal.; Center for Innovative Biomedicine and Biotechnology (CIBB), University of Coimbra, 3004-504 Coimbra, Portugal.; Clinical Academic Center of Coimbra (CACC), 3004-504 Coimbra, Portugal., Fernandes R; Institute of Pharmacology & Experimental Therapeutics & Coimbra Institute for Clinical and Biomedical Research (iCBR), Faculty of Medicine, University of Coimbra, 3000-548 Coimbra, Portugal.; Center for Innovative Biomedicine and Biotechnology (CIBB), University of Coimbra, 3004-504 Coimbra, Portugal.; Clinical Academic Center of Coimbra (CACC), 3004-504 Coimbra, Portugal., Teodoro JS; Department of Life Sciences, Faculty of Science and Technology (FCTUC), University of Coimbra, 3000-456 Coimbra, Portugal.; Center for Neurosciences and Cell Biology of Coimbra (CNC), University of Coimbra, 3004-504 Coimbra, Portugal., Figueirinha A; Faculty of Pharmacy, University of Coimbra, 3000-548 Coimbra, Portugal.; LAQV, REQUIMTE, Faculty of Pharmacy, University of Coimbra, 3000-456 Coimbra, Portugal., Salgueiro L; Faculty of Pharmacy, University of Coimbra, 3000-548 Coimbra, Portugal.; CIEPQPF, Chemical Process Engineering and Forest Products Research Centre, University of Coimbra, 3000-456 Coimbra, Portugal., Silva S; CBQF-Centro de Biotecnologia e Química Fina-Laboratório Associado, Universidade Católica Portuguesa, Escola Superior de Biotecnologia, Rua Diogo Botelho 1327, 4169-005 Porto, Portugal., Jarak I; Department of Microscopy, Laboratory of Cell Biology and Unit for Multidisciplinary Research in Biomedicine (UMIB), Institute of Biomedical Sciences Abel Salazar (ICBAS), University of Porto, 4050-313 Porto, Portugal., Carvalho RA; Department of Life Sciences, Faculty of Science and Technology (FCTUC), University of Coimbra, 3000-456 Coimbra, Portugal.; Associated Laboratory for Green Chemistry-Clean Technologies and Processes, REQUIMTE, Faculty of Sciences and Technology, University of Porto, 4050-313 Porto, Portugal., Cavadas C; Center for Innovative Biomedicine and Biotechnology (CIBB), University of Coimbra, 3004-504 Coimbra, Portugal.; Clinical Academic Center of Coimbra (CACC), 3004-504 Coimbra, Portugal.; Center for Neurosciences and Cell Biology of Coimbra (CNC), University of Coimbra, 3004-504 Coimbra, Portugal.; Faculty of Pharmacy, University of Coimbra, 3000-548 Coimbra, Portugal., Rolo AP; Department of Life Sciences, Faculty of Science and Technology (FCTUC), University of Coimbra, 3000-456 Coimbra, Portugal.; Center for Neurosciences and Cell Biology of Coimbra (CNC), University of Coimbra, 3004-504 Coimbra, Portugal., Palmeira CM; Department of Life Sciences, Faculty of Science and Technology (FCTUC), University of Coimbra, 3000-456 Coimbra, Portugal.; Center for Neurosciences and Cell Biology of Coimbra (CNC), University of Coimbra, 3004-504 Coimbra, Portugal., Pintado MM; CBQF-Centro de Biotecnologia e Química Fina-Laboratório Associado, Universidade Católica Portuguesa, Escola Superior de Biotecnologia, Rua Diogo Botelho 1327, 4169-005 Porto, Portugal., Reis F; Institute of Pharmacology & Experimental Therapeutics & Coimbra Institute for Clinical and Biomedical Research (iCBR), Faculty of Medicine, University of Coimbra, 3000-548 Coimbra, Portugal.; Center for Innovative Biomedicine and Biotechnology (CIBB), University of Coimbra, 3004-504 Coimbra, Portugal.; Clinical Academic Center of Coimbra (CACC), 3004-504 Coimbra, Portugal.

المصدر: Pharmaceutics [Pharmaceutics] 2020 Nov 14; Vol. 12 (11). Date of Electronic Publication: 2020 Nov 14.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101534003 Publication Model: Electronic Cited Medium: Print ISSN: 1999-4923 (Print) Linking ISSN: 19994923 NLM ISO Abbreviation: Pharmaceutics Subsets: PubMed not MEDLINE

المؤلفون: Teodoro JS; Department of Life Sciences of Faculty of Sciences and Technology, of the University of Coimbra, Coimbra, Portugal.; Center for Neurosciences and Cell Biology, of the University of Coimbra, Coimbra, Portugal., Silva R; Center for Neurosciences and Cell Biology, of the University of Coimbra, Coimbra, Portugal., Aguiar A; Chemistry Department, FCTUC, University of Coimbra, Coimbra, Portugal., Sobral AJFN; Chemistry Department, FCTUC, University of Coimbra, Coimbra, Portugal., Rolo AP; Department of Life Sciences of Faculty of Sciences and Technology, of the University of Coimbra, Coimbra, Portugal.; Center for Neurosciences and Cell Biology, of the University of Coimbra, Coimbra, Portugal., Palmeira CM; Department of Life Sciences of Faculty of Sciences and Technology, of the University of Coimbra, Coimbra, Portugal.; Center for Neurosciences and Cell Biology, of the University of Coimbra, Coimbra, Portugal.

المصدر: Toxicology mechanisms and methods [Toxicol Mech Methods] 2020 Sep; Vol. 30 (7), pp. 536-545. Date of Electronic Publication: 2020 Jun 24.

نوع المنشور: Comparative Study; Journal Article

بيانات الدورية: Publisher: Informa Healthcare Country of Publication: England NLM ID: 101134521 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1537-6524 (Electronic) Linking ISSN: 15376516 NLM ISO Abbreviation: Toxicol Mech Methods Subsets: MEDLINE

مواضيع طبية MeSH: Aldehydes/*toxicity , Coffee/*toxicity , Furans/*toxicity , Hepatocytes/*drug effects , Seeds/*toxicity, 8-Hydroxy-2'-Deoxyguanosine/metabolism ; Adenosine Triphosphate/metabolism ; Animals ; Cell Survival/drug effects ; Cells, Cultured ; Cooking ; DNA Damage ; Dose-Response Relationship, Drug ; Hepatocytes/metabolism ; Hepatocytes/pathology ; Hot Temperature ; Humans ; Oxidative Stress/drug effects ; Protein Carbamylation/drug effects ; Rats ; Species Specificity ; Time Factors

المؤلفون: Teodoro JS; Center for Neurosciences and Cell Biology of the University of Coimbra, 3004-504 Coimbra, Portugal.; Department of Life Sciences of the University of Coimbra, 3000-456 Coimbra, Portugal., Amorim JA; Center for Neurosciences and Cell Biology of the University of Coimbra, 3004-504 Coimbra, Portugal.; IIIUC-Institute of Interdisciplinary Research of the University of Coimbra, 3030-789 Coimbra, Portugal.; Department of Genetics, Blavatnik Institute, Paul F. Glenn Center for the Biology of Aging, Harvard Medical School, Boston, MA 02115, USA., Machado IF; Center for Neurosciences and Cell Biology of the University of Coimbra, 3004-504 Coimbra, Portugal.; Department of Life Sciences of the University of Coimbra, 3000-456 Coimbra, Portugal., Castela AC; Center for Neurosciences and Cell Biology of the University of Coimbra, 3004-504 Coimbra, Portugal.; Department of Life Sciences of the University of Coimbra, 3000-456 Coimbra, Portugal., Steegborn C; Department of Biochemistry, University of Bayreuth, 95440 Bayreuth, Germany., Sinclair DA; Department of Genetics, Blavatnik Institute, Paul F. Glenn Center for the Biology of Aging, Harvard Medical School, Boston, MA 02115, USA.; Laboratory for Ageing Research, Department of Pharmacology, School of Medical Sciences, The University of New South Wales, Sydney 2052, Australia., Rolo AP; Center for Neurosciences and Cell Biology of the University of Coimbra, 3004-504 Coimbra, Portugal.; Department of Life Sciences of the University of Coimbra, 3000-456 Coimbra, Portugal., Palmeira CM; Center for Neurosciences and Cell Biology of the University of Coimbra, 3004-504 Coimbra, Portugal.; Department of Life Sciences of the University of Coimbra, 3000-456 Coimbra, Portugal.

المصدر: International journal of molecular sciences [Int J Mol Sci] 2020 Jul 11; Vol. 21 (14). Date of Electronic Publication: 2020 Jul 11.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Adenylyl Cyclase Inhibitors/*therapeutic use , Liver Failure/*prevention & control , Mitochondria, Liver/*drug effects , Pyrimidines/*therapeutic use , Reperfusion Injury/*prevention & control , Thiophenes/*therapeutic use, Adenosine Diphosphate/metabolism ; Adenylyl Cyclase Inhibitors/administration & dosage ; Adenylyl Cyclase Inhibitors/pharmacology ; Adenylyl Cyclases/physiology ; Animals ; Constriction ; Disease Models, Animal ; Gene Expression Regulation/drug effects ; Hepatic Artery ; Hormesis/drug effects ; Liver Failure/enzymology ; Male ; Membrane Potential, Mitochondrial/drug effects ; Mitochondria, Liver/enzymology ; Oxygen Consumption ; Phosphorylation ; Portal Vein ; Premedication ; Pyrimidines/administration & dosage ; Pyrimidines/pharmacology ; Random Allocation ; Rats ; Rats, Wistar ; Reactive Oxygen Species ; Reperfusion Injury/enzymology ; Solubility ; Thiophenes/administration & dosage ; Thiophenes/pharmacology