المؤلفون: Machushynets NV; Molecular Biotechnology, Institute of Biology, Leiden University, Leiden 2333 BE, The Netherlands., Al Ayed K; Biological Chemistry Group, Institute of Biology, Leiden University, Leiden 2333 BE, The Netherlands., Terlouw BR; Bioinformatics Group, Wageningen University, Wageningen 6700 PB, The Netherlands., Du C; Molecular Biotechnology, Institute of Biology, Leiden University, Leiden 2333 BE, The Netherlands., Buijs NP; Biological Chemistry Group, Institute of Biology, Leiden University, Leiden 2333 BE, The Netherlands., Willemse J; Molecular Biotechnology, Institute of Biology, Leiden University, Leiden 2333 BE, The Netherlands., Elsayed SS; Molecular Biotechnology, Institute of Biology, Leiden University, Leiden 2333 BE, The Netherlands., Schill J; BioVersys AG, c/o Technologiepark, Basel CH-4057, Switzerland., Trebosc V; BioVersys AG, c/o Technologiepark, Basel CH-4057, Switzerland., Pieren M; BioVersys AG, c/o Technologiepark, Basel CH-4057, Switzerland., Alexander FM; School of Chemistry and Chemical Engineering, Queen's University of Belfast, Belfast BT9 5AG, United Kingdom., Cochrane SA; School of Chemistry and Chemical Engineering, Queen's University of Belfast, Belfast BT9 5AG, United Kingdom., Liles MR; Department of Biological Sciences, Auburn University, Auburn, Alabama 36849, United States., Medema MH; Bioinformatics Group, Wageningen University, Wageningen 6700 PB, The Netherlands., Martin NI; Biological Chemistry Group, Institute of Biology, Leiden University, Leiden 2333 BE, The Netherlands., van Wezel GP; Molecular Biotechnology, Institute of Biology, Leiden University, Leiden 2333 BE, The Netherlands.; Department of Microbial Ecology, Netherlands Institute of Ecology, Wageningen 6700 PB, The Netherlands.

المصدر: ACS chemical biology [ACS Chem Biol] 2024 May 17; Vol. 19 (5), pp. 1106-1115. Date of Electronic Publication: 2024 Apr 11.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101282906 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1554-8937 (Electronic) Linking ISSN: 15548929 NLM ISO Abbreviation: ACS Chem Biol Subsets: MEDLINE

مواضيع طبية MeSH: Anti-Bacterial Agents*/pharmacology , Anti-Bacterial Agents*/chemistry , Pseudomonas aeruginosa*/drug effects , Microbial Sensitivity Tests*, Humans ; Host Specificity ; Drug Discovery ; Lipopeptides/pharmacology ; Lipopeptides/chemistry ; Peptides

المؤلفون: Mullowney MW; Duchossois Family Institute, The University of Chicago, Chicago, IL, USA., Duncan KR; Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, UK., Elsayed SS; Department of Molecular Biotechnology, Institute of Biology, Leiden University, Leiden, The Netherlands., Garg N; School of Chemistry and Biochemistry, Center for Microbial Dynamics and Infection, Georgia Institute of Technology, Atlanta, GA, USA., van der Hooft JJJ; Bioinformatics Group, Wageningen University, Wageningen, The Netherlands.; Department of Biochemistry, University of Johannesburg, Johannesburg, South Africa., Martin NI; Biological Chemistry Group, Institute of Biology, Leiden University, Leiden, The Netherlands., Meijer D; Bioinformatics Group, Wageningen University, Wageningen, The Netherlands., Terlouw BR; Bioinformatics Group, Wageningen University, Wageningen, The Netherlands., Biermann F; Bioinformatics Group, Wageningen University, Wageningen, The Netherlands.; Institute of Molecular Bio Science, Goethe-University Frankfurt, Frankfurt am Main, Germany.; LOEWE Center for Translational Biodiversity Genomics (TBG), Frankfurt am Main, Germany., Blin K; The Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Kongens Lyngby, Denmark., Durairaj J; Biozentrum, University of Basel, Basel, Switzerland., Gorostiola González M; Drug Discovery and Safety, Leiden Academic Centre for Drug Research, Leiden, The Netherlands.; ONCODE institute, Leiden, The Netherlands., Helfrich EJN; Institute of Molecular Bio Science, Goethe-University Frankfurt, Frankfurt am Main, Germany.; LOEWE Center for Translational Biodiversity Genomics (TBG), Frankfurt am Main, Germany., Huber F; Center for Digitalization and Digitality, Hochschule Düsseldorf, Düsseldorf, Germany., Leopold-Messer S; Institut für Mikrobiologie, Eidgenössische Technische Hochschule (ETH) Zürich, Zürich, Switzerland., Rajan K; Institute for Inorganic and Analytical Chemistry, Friedrich-Schiller-University Jena, Jena, Germany., de Rond T; School of Chemical Sciences, University of Auckland, Auckland, New Zealand., van Santen JA; Department of Chemistry, Simon Fraser University, Burnaby, British Columbia, Canada., Sorokina M; Institute for Inorganic and Analytical Chemistry, Friedrich-Schiller University, Jena, Germany.; Pharmaceuticals R&D, Bayer AG, Berlin, Germany., Balunas MJ; Department of Microbiology and Immunology, University of Michigan, Ann Arbor, MI, USA.; Department of Medicinal Chemistry, University of Michigan, Ann Arbor, MI, USA., Beniddir MA; Équipe 'Chimie des Substances Naturelles', Université Paris-Saclay, CNRS, BioCIS, Orsay, France., van Bergeijk DA; Department of Molecular Biotechnology, Institute of Biology, Leiden University, Leiden, The Netherlands., Carroll LM; Structural and Computational Biology Unit, EMBL, Heidelberg, Germany., Clark CM; Division of Pharmaceutical Sciences, School of Pharmacy, University of Wisconsin-Madison, Madison, WI, USA., Clevert DA; WRDM - Machine Learning Research, Pfizer, Berlin, Germany., Dejong CA; Adapsyn Bioscience, Hamilton, Ontario, Canada., Du C; Department of Molecular Biotechnology, Institute of Biology, Leiden University, Leiden, The Netherlands., Ferrinho S; Chemistry Department, University of St Andrews, St Andrews, UK., Grisoni F; Institute for Complex Molecular Systems, Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, The Netherlands.; Centre for Living Technologies, Alliance TU/e, WUR, UU, UMC Utrecht, Utrecht, The Netherlands., Hofstetter A; Laboratory of Physical Chemistry, ETH Zürich, Zürich, Switzerland., Jespers W; Drug Discovery and Safety, Leiden Academic Centre for Drug Research, Leiden, The Netherlands., Kalinina OV; Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Centre for Infection Research (HZI), Saarbrücken, Germany.; Drug Bioinformatics, Medical Faculty, Saarland University, Homburg, Germany.; Center for Bioinformatics, Saarland University, Saarbrücken, Germany., Kautsar SA; Department of Chemistry, Scripps Research, FL, USA., Kim H; College of Pharmacy and Integrated Research Institute for Drug Development, Dongguk University Seoul, Goyang-si, Republic of Korea., Leao TF; Center for Nuclear Energy in Agriculture, University of São Paulo, Piracicaba, Brazil., Masschelein J; Center for Microbiology, VIB-KU Leuven, Heverlee, Belgium.; Department of Biology, KU Leuven, Heverlee, Belgium., Rees ER; Division of Pharmaceutical Sciences, School of Pharmacy, University of Wisconsin-Madison, Madison, WI, USA., Reher R; Institute of Pharmaceutical Biology and Biotechnology, University of Marburg, Marburg, Germany.; Institute of Pharmacy, Martin-Luther-University Halle-Wittenberg, Halle (Saale), Germany., Reker D; Department of Biomedical Engineering, Duke University, Durham, NC, USA.; Duke Microbiome Center, Duke University, Durham, NC, USA., Schwaller P; Laboratory of Artificial Chemical Intelligence, Institut des Sciences et Ingénierie Chimiques, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland., Segler M; Microsoft Research, Cambridge, UK., Skinnider MA; Adapsyn Bioscience, Hamilton, Ontario, Canada.; Michael Smith Laboratories, University of British Columbia, Vancouver, British Columbia, Canada., Walker AS; Department of Chemistry, Vanderbilt University, Nashville, TN, USA.; Department of Biological Sciences, Vanderbilt University, Nashville, TN, USA., Willighagen EL; Department of Bioinformatics - BiGCaT, NUTRIM, Maastricht University, Maastricht, The Netherlands., Zdrazil B; European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Cambridgeshire, UK., Ziemert N; Interfaculty Institute for Microbiology and Infection Medicine Tuebingen (IMIT), Institute for Bioinformatics and Medical Informatics (IBMI), University of Tuebingen, Tuebingen, Germany., Goss RJM; Chemistry Department, University of St Andrews, St Andrews, UK., Guyomard P; Bonsai team, CRIStAL - Centre de Recherche en Informatique Signal et Automatique de Lille, Université de Lille, Villeneuve d'Ascq Cedex, France., Volkamer A; Center for Bioinformatics, Saarland University, Saarbrücken, Germany.; In silico Toxicology and Structural Bioinformatics, Institute of Physiology, Charité - Universitätsmedizin Berlin, Berlin, Germany., Gerwick WH; Scripps Institution of Oceanography, University of California San Diego, La Jolla, CA, USA., Kim HU; Department of Chemical and Biomolecular Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Korea., Müller R; Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Centre for Infection Research (HZI), Saarbrücken, Germany.; Department of Pharmacy, Saarland University, Saarbrücken, Germany.; German Center for infection research (DZIF), Braunschweig, Germany.; Helmholtz International Lab for Anti-Infectives, Saarbrücken, Germany., van Wezel GP; Department of Molecular Biotechnology, Institute of Biology, Leiden University, Leiden, The Netherlands.; Netherlands Institute of Ecology, NIOO-KNAW, Wageningen, The Netherlands., van Westen GJP; Drug Discovery and Safety, Leiden Academic Centre for Drug Research, Leiden, The Netherlands. gerard@lacdr.leidenuniv.nl., Hirsch AKH; Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Centre for Infection Research (HZI), Saarbrücken, Germany. anna.hirsch@helmholtz-hips.de.; Department of Pharmacy, Saarland University, Saarbrücken, Germany. anna.hirsch@helmholtz-hips.de.; German Center for infection research (DZIF), Braunschweig, Germany. anna.hirsch@helmholtz-hips.de.; Helmholtz International Lab for Anti-Infectives, Saarbrücken, Germany. anna.hirsch@helmholtz-hips.de., Linington RG; Department of Chemistry, Simon Fraser University, Burnaby, British Columbia, Canada. rliningt@sfu.ca., Robinson SL; Department of Environmental Microbiology, Eawag: Swiss Federal Institute for Aquatic Science and Technology, Dübendorf, Switzerland. serina.robinson@eawag.ch., Medema MH; Bioinformatics Group, Wageningen University, Wageningen, The Netherlands. marnix.medema@wur.nl.; Institute of Biology, Leiden University, Leiden, The Netherlands. marnix.medema@wur.nl.

المصدر: Nature reviews. Drug discovery [Nat Rev Drug Discov] 2023 Nov; Vol. 22 (11), pp. 895-916. Date of Electronic Publication: 2023 Sep 11.

نوع المنشور: Journal Article; Review; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101124171 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1474-1784 (Electronic) Linking ISSN: 14741776 NLM ISO Abbreviation: Nat Rev Drug Discov Subsets: MEDLINE

مواضيع طبية MeSH: Artificial Intelligence* , Biological Products*/pharmacology, Humans ; Algorithms ; Machine Learning ; Drug Discovery ; Drug Design

المؤلفون: Blin K; The Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Kgs.Lyngby, Denmark., Shaw S; The Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Kgs.Lyngby, Denmark., Augustijn HE; Molecular Biotechnology, Institute of Biology, Leiden University, Leiden, The Netherlands.; Bioinformatics Group, Wageningen University, Wageningen, The Netherlands., Reitz ZL; Bioinformatics Group, Wageningen University, Wageningen, The Netherlands., Biermann F; Bioinformatics Group, Wageningen University, Wageningen, The Netherlands.; Institute of Molecular Bio Science, Goethe-University Frankfurt, Frankfurt am Main, Germany.; LOEWE Center for Translational Biodiversity Genomics. Frankfurt am Main, Germany., Alanjary M; Bioinformatics Group, Wageningen University, Wageningen, The Netherlands., Fetter A; Bioinformatics Group, Wageningen University, Wageningen, The Netherlands.; Institute of Technical Chemistry, Leibniz University Hannover, Hannover, Germany., Terlouw BR; Bioinformatics Group, Wageningen University, Wageningen, The Netherlands., Metcalf WW; Department of Microbiology, University of Illinois Urbana-Champaign, Urbana, IL, USA.; Institute for Genomic Biology, University of Illinois Urbana-Champaign, Urbana, IL, USA., Helfrich EJN; Institute of Molecular Bio Science, Goethe-University Frankfurt, Frankfurt am Main, Germany.; LOEWE Center for Translational Biodiversity Genomics. Frankfurt am Main, Germany., van Wezel GP; Molecular Biotechnology, Institute of Biology, Leiden University, Leiden, The Netherlands., Medema MH; Bioinformatics Group, Wageningen University, Wageningen, The Netherlands., Weber T; The Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Kgs.Lyngby, Denmark.

المصدر: Nucleic acids research [Nucleic Acids Res] 2023 Jul 05; Vol. 51 (W1), pp. W46-W50.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE

مواضيع طبية MeSH: Software* , Computers*, Bacteria/genetics ; Bacteria/metabolism ; Archaea/genetics ; Genome, Microbial ; Multigene Family ; Secondary Metabolism/genetics

المؤلفون: Nieuwkoop T; Laboratory of Microbiology, Wageningen University, Wageningen, Stippeneng 4, 6708 WE, The Netherlands., Terlouw BR; Bioinformatics Group, Wageningen University, Wageningen, Droevendaalsesteeg 1, 6708 PB, The Netherlands., Stevens KG; Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, University of Utrecht, Padualaan 8, 3584 CH Utrecht, The Netherlands.; Netherlands Proteomics Center, Padualaan 8, 3584 CH Utrecht, The Netherlands., Scheltema RA; Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, University of Utrecht, Padualaan 8, 3584 CH Utrecht, The Netherlands.; Netherlands Proteomics Center, Padualaan 8, 3584 CH Utrecht, The Netherlands., de Ridder D; Bioinformatics Group, Wageningen University, Wageningen, Droevendaalsesteeg 1, 6708 PB, The Netherlands., van der Oost J; Laboratory of Microbiology, Wageningen University, Wageningen, Stippeneng 4, 6708 WE, The Netherlands., Claassens NJ; Laboratory of Microbiology, Wageningen University, Wageningen, Stippeneng 4, 6708 WE, The Netherlands.

المصدر: Nucleic acids research [Nucleic Acids Res] 2023 Mar 21; Vol. 51 (5), pp. 2363-2376.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE

مواضيع طبية MeSH: Escherichia coli*/genetics , Escherichia coli*/metabolism , Machine Learning*, Random Allocation ; Codon/genetics ; Codon/metabolism ; RNA, Messenger/metabolism ; Protein Biosynthesis

المؤلفون: Terlouw BR; Bioinformatics Group, Wageningen University, Droevendaalsesteeg, 6708 PB Wageningen, The Netherlands., Blin K; The Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Kgs. Lyngby, Denmark., Navarro-Muñoz JC; Bioinformatics Group, Wageningen University, Droevendaalsesteeg, 6708 PB Wageningen, The Netherlands.; Westerdijk Fungal Biodiversity Institute, Uppsalalaan 8, 3584 CT Utrecht, The Netherlands., Avalon NE; Scripps Institution of Oceanography, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0212, USA., Chevrette MG; Department of Microbiology and Cell Science, University of Florida, Gainesville, FL 32611, USA., Egbert S; Department of Chemistry, University of Manitoba, 66 Chancellors Cir, Winnipeg, MB R3T 2N2, Canada., Lee S; Department of Chemistry, Simon Fraser University, 8888 University Drive, Burnaby, British Columbia V5A 1S6, Canada., Meijer D; Bioinformatics Group, Wageningen University, Droevendaalsesteeg, 6708 PB Wageningen, The Netherlands., Recchia MJJ; Department of Chemistry, Simon Fraser University, 8888 University Drive, Burnaby, British Columbia V5A 1S6, Canada., Reitz ZL; Bioinformatics Group, Wageningen University, Droevendaalsesteeg, 6708 PB Wageningen, The Netherlands., van Santen JA; Department of Chemistry, Simon Fraser University, 8888 University Drive, Burnaby, British Columbia V5A 1S6, Canada.; Unnatural Products, 2161 Delaware Ave. Suite A, Santa Cruz, CA 95060, USA., Selem-Mojica N; Centro de Ciencias Matemáticas UNAM, Morelia, México., Tørring T; Department of Biological and Chemical Engineering, Aarhus University, Denmark., Zaroubi L; Department of Chemistry, Simon Fraser University, 8888 University Drive, Burnaby, British Columbia V5A 1S6, Canada., Alanjary M; Bioinformatics Group, Wageningen University, Droevendaalsesteeg, 6708 PB Wageningen, The Netherlands., Aleti G; Food and Animal Sciences, Department of Agricultural and Environmental Sciences, Tennessee State University, Nashville, TN 37209, USA., Aguilar C; Department of Chemistry, Purdue University, West Lafayette, IN, USA., Al-Salihi SAA; Department of Applied Sciences, University of Technology, Iraq., Augustijn HE; Bioinformatics Group, Wageningen University, Droevendaalsesteeg, 6708 PB Wageningen, The Netherlands.; Institute of Biology, Leiden University, Sylviusweg 72, 2333BE Leiden, The Netherlands., Avelar-Rivas JA; Laboratorio Nacional de Genómica para la Biodiversidad-Unidad de Genómica Avanzada, Cinvestav. Km 9.6 Libramiento Norte Carretera Irapuato-León, CP 36824 Irapuato, Gto., México., Avitia-Domínguez LA; Institute of Biology, Leiden University, Sylviusweg 72, 2333BE Leiden, The Netherlands.; Laboratorio Nacional de Genómica para la Biodiversidad-Unidad de Genómica Avanzada, Cinvestav. Km 9.6 Libramiento Norte Carretera Irapuato-León, CP 36824 Irapuato, Gto., México., Barona-Gómez F; Institute of Biology, Leiden University, Sylviusweg 72, 2333BE Leiden, The Netherlands.; Laboratorio Nacional de Genómica para la Biodiversidad-Unidad de Genómica Avanzada, Cinvestav. Km 9.6 Libramiento Norte Carretera Irapuato-León, CP 36824 Irapuato, Gto., México., Bernaldo-Agüero J; Departamento de Microbiología Molecular, Instituto de Biotecnología, Universidad Nacional Autónoma de México, Cuernavaca, Morelos, México., Bielinski VA; Synthetic Biology and Bioenergy Group, J. Craig Venter Institute, La Jolla, CA 92037, USA., Biermann F; Bioinformatics Group, Wageningen University, Droevendaalsesteeg, 6708 PB Wageningen, The Netherlands.; Institute of Molecular Bio Science, Goethe-University Frankfurt, D-60438 Frankfurt am Main, Germany.; LOEWE Center for Translational Biodiversity Genomics (TBG), Senckenberganlage 25, 60325 Frankfurt am Main, Germany., Booth TJ; The Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Kgs. Lyngby, Denmark.; School of Molecular Sciences, University of Western Australia, Perth, Australia., Carrion Bravo VJ; Institute of Biology, Leiden University, Sylviusweg 72, 2333BE Leiden, The Netherlands.; Departamento de Microbiología, Instituto de Hortofruticultura Subtropical y Mediterránea 'La Mayora', Universidad de Málaga-Consejo Superior de Investigaciones Científicas (IHSM-UMA-CSIC), Universidad de Málaga, Málaga, Spain.; Department of Microbial Ecology, Netherlands Institute of Ecology (NIOO-KNAW), Wageningen, The Netherlands., Castelo-Branco R; Interdisciplinary Centre of Marine and Environmental Research (CIIMAR), University of Porto, Portugal.; Faculty of Sciences, University of Porto, 4150-179 Porto, Portugal., Chagas FO; Instituto de Pesquisas de Produtos Naturais Walter Mors, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, 21941-599, Brazil., Cruz-Morales P; The Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Kgs. Lyngby, Denmark., Du C; Institute of Biology, Leiden University, Sylviusweg 72, 2333BE Leiden, The Netherlands., Duncan KR; University of Strathclyde, Strathclyde Institute of Pharmacy and Biomedical Sciences, 141 Cathedral Street, Glasgow, G4 ORE UK., Gavriilidou A; Translational Genome Mining for Natural Products, Interfaculty Institute of Microbiology and Infection Medicine Tübingen (IMIT), University of Tübingen, Tübingen, Germany.; Interfaculty Institute for Biomedical Informatics (IBMI), University of Tübingen, Tübingen, Germany., Gayrard D; Department of Molecular Microbiology, John Innes Centre, Norwich Research Park, Norwich, NR4 7UH, UK., Gutiérrez-García K; Department of Embryology, Carnegie Institution for Science, 3520 San Martin Drive, Baltimore, MD 21218, USA., Haslinger K; Department of Chemical and Pharmaceutical Biology, Groningen Research Institute of Pharmacy, University of Groningen, Antonius Deusinglaan 1, 9713 AV Groningen, The Netherlands., Helfrich EJN; Institute of Molecular Bio Science, Goethe-University Frankfurt, D-60438 Frankfurt am Main, Germany.; LOEWE Center for Translational Biodiversity Genomics (TBG), Senckenberganlage 25, 60325 Frankfurt am Main, Germany., van der Hooft JJJ; Bioinformatics Group, Wageningen University, Droevendaalsesteeg, 6708 PB Wageningen, The Netherlands.; Department of Biochemistry, University of Johannesburg, Auckland Park, Johannesburg 2006, South Africa., Jati AP; Indonesian Society of Bioinformatics And Biodiversity, Indonesia., Kalkreuter E; Department of Chemistry, University of Florida Scripps Biomedical Research, 110 Scripps Way, Jupiter, FL 33458, USA., Kalyvas N; Westerdijk Fungal Biodiversity Institute, Uppsalalaan 8, 3584 CT Utrecht, The Netherlands., Kang KB; College of Pharmacy, Sookmyung Women's University, Seoul, South Korea., Kautsar S; Department of Chemistry, University of Florida Scripps Biomedical Research, 110 Scripps Way, Jupiter, FL 33458, USA., Kim W; Korean Lichen Research Institute, Sunchon National Universtiy, Suncheon, South Korea., Kunjapur AM; Department of Chemical & Biomolecular Engineering, University of Delaware, Newark, DE 19716, USA., Li YX; Department of Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong, P.R. China., Lin GM; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA., Loureiro C; Laboratory of Microbiology, Wageningen University, Stippeneng 4, 6708WE, Wageningen, The Netherlands., Louwen JJR; Bioinformatics Group, Wageningen University, Droevendaalsesteeg, 6708 PB Wageningen, The Netherlands., Louwen NLL; Bioinformatics Group, Wageningen University, Droevendaalsesteeg, 6708 PB Wageningen, The Netherlands., Lund G; Sustainable Soils and Crops, Rothamsted Research, Harpenden, Hertfordshire, UK., Parra J; Instituto de Investigaciones Farmacéuticas (INIFAR), Facultad de Farmacia, Universidad de Costa Rica, San José, 11501-2060, Costa Rica.; Centro de Investigaciones en Productos Naturales (CIPRONA), Universidad de Costa Rica, San José, 11501-2060, Costa Rica.; Centro Nacional de Innovaciones Biotecnológicas (CENIBiot), CeNAT-CONARE, 1174-1200, San José, Costa Rica., Philmus B; Department of Pharmaceutical Sciences, Oregon State University, USA., Pourmohsenin B; Translational Genome Mining for Natural Products, Interfaculty Institute of Microbiology and Infection Medicine Tübingen (IMIT), University of Tübingen, Tübingen, Germany.; Interfaculty Institute for Biomedical Informatics (IBMI), University of Tübingen, Tübingen, Germany., Pronk LJU; Bioinformatics Group, Wageningen University, Droevendaalsesteeg, 6708 PB Wageningen, The Netherlands., Rego A; Interdisciplinary Centre of Marine and Environmental Research (CIIMAR), University of Porto, Portugal.; Institute of Biomedical Sciences Abel Salazar (ICBAS), University of Porto, Portugal., Rex DAB; Centre for Integrative Omics Data Science, Yenepoya (Deemed to be University), Mangalore 575018, India., Robinson S; Department of Environmental Microbiology, Eawag: Swiss Federal Institute for Aquatic Science and Technology, Überlandstrasse 133, CH-8600 Dübendorf, Switzerland., Rosas-Becerra LR; Institute of Biology, Leiden University, Sylviusweg 72, 2333BE Leiden, The Netherlands.; Laboratorio Nacional de Genómica para la Biodiversidad-Unidad de Genómica Avanzada, Cinvestav. Km 9.6 Libramiento Norte Carretera Irapuato-León, CP 36824 Irapuato, Gto., México., Roxborough ET; School of Chemistry, University of Nottingham, University Park, Nottingham NG7 2RD, UK., Schorn MA; Laboratory of Microbiology, Wageningen University, Stippeneng 4, 6708WE, Wageningen, The Netherlands., Scobie DJ; University of Strathclyde, Strathclyde Institute of Pharmacy and Biomedical Sciences, 141 Cathedral Street, Glasgow, G4 ORE UK., Singh KS; Bioinformatics Group, Wageningen University, Droevendaalsesteeg, 6708 PB Wageningen, The Netherlands., Sokolova N; Department of Chemical and Pharmaceutical Biology, Groningen Research Institute of Pharmacy, University of Groningen, Antonius Deusinglaan 1, 9713 AV Groningen, The Netherlands., Tang X; Institute of Chemical Biology, Shenzhen Bay Laboratory, Shenzhen 518132, China., Udwary D; DOE Joint Genome Institute, Lawrence Berkeley National Lab, Berkeley, CA, USA., Vigneshwari A; Department of Microbiology, University of Szeged, Hungary., Vind K; Host-Microbe Interactomics Group, Wageningen University, 6708 WD Wageningen, The Netherlands.; NAICONS Srl, 20139 Milan, Italy., Vromans SPJM; Bioinformatics Group, Wageningen University, Droevendaalsesteeg, 6708 PB Wageningen, The Netherlands., Waschulin V; School of Life Sciences, The University of Warwick, Coventry CV4 7AL, UK., Williams SE; School of Biochemistry, University of Bristol, University Walk, Bristol BS8 1TD, UK., Winter JM; Department of Medicinal Chemistry, University of Utah, Salt Lake City, UT 84112, USA., Witte TE; Department of Chemistry and Biomolecular Sciences, University of Ottawa, Ottawa, Canada., Xie H; Bioinformatics Group, Wageningen University, Droevendaalsesteeg, 6708 PB Wageningen, The Netherlands.; Key laboratory of Detection for Biotoxins, Ministry of Agriculture and Rural Affairs and Oil Crops Research Institute, Chinese Academy of Agricultural Sciences, Wuhan 430061, China., Yang D; Department of Chemistry and Natural Products Discovery Center, UF Scripps Biomedical Research, University of Florida, Jupiter, FL 33458, USA., Yu J; SUSTech-PKU Institute of Plant and Food Science, Department of Biology, School of Life Sciences, Southern University of Science and Technology, Shenzhen, Guangdong 518055, China., Zdouc M; Bioinformatics Group, Wageningen University, Droevendaalsesteeg, 6708 PB Wageningen, The Netherlands., Zhong Z; Laboratory of Microbiology, Wageningen University, Stippeneng 4, 6708WE, Wageningen, The Netherlands., Collemare J; Westerdijk Fungal Biodiversity Institute, Uppsalalaan 8, 3584 CT Utrecht, The Netherlands., Linington RG; Department of Chemistry, Simon Fraser University, 8888 University Drive, Burnaby, British Columbia V5A 1S6, Canada., Weber T; The Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Kgs. Lyngby, Denmark., Medema MH; Bioinformatics Group, Wageningen University, Droevendaalsesteeg, 6708 PB Wageningen, The Netherlands.; Institute of Biology, Leiden University, Sylviusweg 72, 2333BE Leiden, The Netherlands.

المصدر: Nucleic acids research [Nucleic Acids Res] 2023 Jan 06; Vol. 51 (D1), pp. D603-D610.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE

مواضيع طبية MeSH: Genomics* , Genome*, Multigene Family ; Biosynthetic Pathways/genetics

المؤلفون: Terlouw BR; Bioinformatics Group, Wageningen University, Droevendaalsesteeg 1, 6708 PB, Wageningen, The Netherlands. barbara.terlouw@wur.nl., Vromans SPJM; Bioinformatics Group, Wageningen University, Droevendaalsesteeg 1, 6708 PB, Wageningen, The Netherlands., Medema MH; Bioinformatics Group, Wageningen University, Droevendaalsesteeg 1, 6708 PB, Wageningen, The Netherlands. marnix.medema@wur.nl.

المصدر: Journal of cheminformatics [J Cheminform] 2022 Jun 07; Vol. 14 (1), pp. 34. Date of Electronic Publication: 2022 Jun 07.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 101516718 Publication Model: Electronic Cited Medium: Print ISSN: 1758-2946 (Print) Linking ISSN: 17582946 NLM ISO Abbreviation: J Cheminform Subsets: PubMed not MEDLINE

المؤلفون: Tracanna V; Bioinformatics Group, Wageningen University and Research, Wageningen, The Netherlands., Ossowicki A; Microbial Ecology, Netherlands Institute of Ecology (NIOO-KNAW), Wageningen, The Netherlands., Petrus MLC; Microbial Biotechnology, Leiden Institute of Biology, Leiden, The Netherlands., Overduin S; Bioinformatics Group, Wageningen University and Research, Wageningen, The Netherlands., Terlouw BR; Bioinformatics Group, Wageningen University and Research, Wageningen, The Netherlands., Lund G; Biointeractions and Crop Protection, Rothamsted Research, Harpenden, United Kingdom., Robinson SL; BioTechnology Institute, University of Minnesota-Twin Cities, Falcon Heights, Minnesota, USA., Warris S; Bioscience, Wageningen University and Research, Wageningen, The Netherlands., Schijlen EGWM; Bioscience, Wageningen University and Research, Wageningen, The Netherlands., van Wezel GP; Microbial Ecology, Netherlands Institute of Ecology (NIOO-KNAW), Wageningen, The Netherlands.; Microbial Biotechnology, Leiden Institute of Biology, Leiden, The Netherlands., Raaijmakers JM; Microbial Ecology, Netherlands Institute of Ecology (NIOO-KNAW), Wageningen, The Netherlands.; Microbial Biotechnology, Leiden Institute of Biology, Leiden, The Netherlands., Garbeva P; Microbial Ecology, Netherlands Institute of Ecology (NIOO-KNAW), Wageningen, The Netherlands., Medema MH; Bioinformatics Group, Wageningen University and Research, Wageningen, The Netherlands.

المصدر: MSystems [mSystems] 2021 Jun 29; Vol. 6 (3), pp. e0111620. Date of Electronic Publication: 2021 Jun 08.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 101680636 Publication Model: Print-Electronic Cited Medium: Print ISSN: 2379-5077 (Print) Linking ISSN: 23795077 NLM ISO Abbreviation: mSystems Subsets: PubMed not MEDLINE

المؤلفون: Robinson SL; BioTechnology Institute, University of Minnesota, Saint Paul, Minnesota, USA; Graduate Program in Bioinformatics and Computational Biology, University of Minnesota, Rochester, Minnesota, USA; Graduate Program in Microbiology, Immunology, and Cancer Biology, University of Minnesota, Minneapolis, Minnesota, USA. Electronic address: robi0916@umn.edu., Terlouw BR; Bioinformatics Group, Wageningen University & Research, Wageningen, The Netherlands., Smith MD; BioTechnology Institute, University of Minnesota, Saint Paul, Minnesota, USA; Graduate Program in Microbiology, Immunology, and Cancer Biology, University of Minnesota, Minneapolis, Minnesota, USA., Pidot SJ; Department of Microbiology and Immunology at the Doherty Institute, University of Melbourne, Melbourne, Victoria, Australia., Stinear TP; Department of Microbiology and Immunology at the Doherty Institute, University of Melbourne, Melbourne, Victoria, Australia., Medema MH; Bioinformatics Group, Wageningen University & Research, Wageningen, The Netherlands., Wackett LP; BioTechnology Institute, University of Minnesota, Saint Paul, Minnesota, USA; Graduate Program in Bioinformatics and Computational Biology, University of Minnesota, Rochester, Minnesota, USA; Graduate Program in Microbiology, Immunology, and Cancer Biology, University of Minnesota, Minneapolis, Minnesota, USA.

المصدر: The Journal of biological chemistry [J Biol Chem] 2020 Oct 30; Vol. 295 (44), pp. 14826-14839. Date of Electronic Publication: 2020 Aug 21.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE

مواضيع طبية MeSH: Adenosine Monophosphate/*biosynthesis , Lactones/*metabolism , Ligases/*metabolism , Nocardia/*metabolism, Catalysis ; Ligases/genetics ; Machine Learning ; Multigene Family ; Nocardia/enzymology ; Phylogeny ; Reproducibility of Results ; Substrate Specificity

SCR Organism: Nocardia brasiliensis

المؤلفون: van Bergeijk DA; Microbial Biotechnology, Institute of Biology, Leiden University, Leiden, The Netherlands., Terlouw BR; Bioinformatics Group, Wageningen University, Wageningen, The Netherlands., Medema MH; Bioinformatics Group, Wageningen University, Wageningen, The Netherlands. marnix.medema@wur.nl., van Wezel GP; Microbial Biotechnology, Institute of Biology, Leiden University, Leiden, The Netherlands. g.wezel@biology.leidenuniv.nl.; Department of Microbial Ecology, Netherlands Institute of Ecology, Wageningen, The Netherlands. g.wezel@biology.leidenuniv.nl.

المصدر: Nature reviews. Microbiology [Nat Rev Microbiol] 2020 Oct; Vol. 18 (10), pp. 546-558. Date of Electronic Publication: 2020 Jun 01.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Review

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101190261 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1740-1534 (Electronic) Linking ISSN: 17401526 NLM ISO Abbreviation: Nat Rev Microbiol Subsets: MEDLINE

مواضيع طبية MeSH: Gene Expression Regulation, Bacterial* , Genes, Bacterial* , Genome, Bacterial*, Actinobacteria/*genetics , Anti-Bacterial Agents/*isolation & purification , Biological Products/*isolation & purification, Actinobacteria/metabolism ; Anti-Bacterial Agents/biosynthesis ; Anti-Bacterial Agents/pharmacology ; Biological Products/metabolism ; Biological Products/pharmacology ; Drug Discovery ; Ecology ; Gene Transfer, Horizontal ; Genomics/methods ; Humans ; Metabolic Networks and Pathways/genetics ; Multigene Family

المؤلفون: Kautsar SA; Bioinformatics Group, Wageningen University, Wageningen, NL, The Netherlands., Blin K; Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Lyngby, DK, The Netherlands., Shaw S; Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Lyngby, DK, The Netherlands., Navarro-Muñoz JC; Fungal Natural Products Group, Westerdijk Fungal Biodiversity Institute, Utrecht, NL, The Netherlands., Terlouw BR; Bioinformatics Group, Wageningen University, Wageningen, NL, The Netherlands., van der Hooft JJJ; Bioinformatics Group, Wageningen University, Wageningen, NL, The Netherlands., van Santen JA; Department of Chemistry, Simon Fraser University, Burnaby, CA, USA., Tracanna V; Bioinformatics Group, Wageningen University, Wageningen, NL, The Netherlands., Suarez Duran HG; Bioinformatics Group, Wageningen University, Wageningen, NL, The Netherlands., Pascal Andreu V; Bioinformatics Group, Wageningen University, Wageningen, NL, The Netherlands., Selem-Mojica N; Evolution of Metabolic Diversity Laboratory, Langebio, Cinvestav-IPN, Irapuato, MX, Mexico., Alanjary M; Bioinformatics Group, Wageningen University, Wageningen, NL, The Netherlands., Robinson SL; BioTechnology Institute, University of Minnesota-Twin Cities, MN, USA., Lund G; Biointeractions and Crop Protection, Rothamsted Research, Harpenden, UK., Epstein SC; Department of Chemistry, Haverford College, Haverford, PA, USA., Sisto AC; Department of Chemistry, Haverford College, Haverford, PA, USA., Charkoudian LK; Department of Chemistry, Haverford College, Haverford, PA, USA., Collemare J; Fungal Natural Products Group, Westerdijk Fungal Biodiversity Institute, Utrecht, NL, The Netherlands., Linington RG; Department of Chemistry, Simon Fraser University, Burnaby, CA, USA., Weber T; Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Lyngby, DK, The Netherlands., Medema MH; Bioinformatics Group, Wageningen University, Wageningen, NL, The Netherlands.

المصدر: Nucleic acids research [Nucleic Acids Res] 2020 Jan 08; Vol. 48 (D1), pp. D454-D458.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE

مواضيع طبية MeSH: Databases, Genetic* , Genome, Bacterial* , Multigene Family* , Software*, Genomics/*methods, Biosynthetic Pathways/genetics ; Molecular Sequence Annotation