المؤلفون: Svante Pääbo, Henrik Kaessmann, Thoomke Brüning, Frank Grützner, Philipp Khaitovich, Francesco Lamanna, Mari Sepp, Meritxell Riera Belles, Julia Schmidt, Katharina Mößinger, Christian Conrad, Rüdiger Behr, Celine Schneider, Ronald E. Bontrop, Sofia B. Winge, Kristian Almstrup, Timo Trefzer, Florent Murat, Ivanela Kondova, Margarida Cardoso-Moreira, Evgeny Leushkin, Noe Mbengue, Mikkel H. Schierup, Tomas Marques-Bonet

المساهمون: Theoretical Biology and Bioinformatics, Sub Theoretical Biology, Center for Molecular Biology - Zentrum für Molekulare Biologie [Heidelberg, Germany] (ZMBH), Universität Heidelberg [Heidelberg], Aarhus University [Aarhus], University of Copenhagen = Københavns Universitet (KU), Berlin Institute of Health (BIH), Charité - UniversitätsMedizin = Charité - University Hospital [Berlin], The Francis Crick Institute [London], Biomedical Primate Research Centre [Rijswijk] (BPRC), German Primate Center - Deutsches Primatenzentrum -- Leibniz Insitute for Primate Research -- [Göttingen, Allemagne] (GPC - DPZ), German Center for Cardiovascular Research (DZHK), Skolkovo Institute of Science and Technology [Moscow] (Skoltech), Max Planck Institute for Evolutionary Anthropology [Leipzig], Max-Planck-Gesellschaft, Institut de Biologia Evolutiva [Barcelona] (IBE / UPF - CSIC), Universitat Pompeu Fabra [Barcelona] (UPF), Institució Catalana de Recerca i Estudis Avançats (ICREA), Centre for Genomic Regulation [Barcelona] (CRG), Universitat Pompeu Fabra [Barcelona] (UPF)-Centro Nacional de Analisis Genomico [Barcelona] (CNAG), Barcelona Institute of Science and Technology (BIST), Universitat Autònoma de Barcelona (UAB), Robinson Research Institute, University of Adelaide

المصدر: Murat, F, Mbengue, N, Winge, S, Trefzer, T, Leushkin, E, Sepp, M, Cardoso-Moreira, M, Schmidt, J, Schneider, C, Mößinger, K, Brüning, T, Lamanna, F, Riera Belles, M, Conrad, C, Kondova, I, Bontrop, R, Behr, R, Khaitovich, P, Pääbo, S, Marques-Bonet, T, Grützner, F, Almstrup, K, Schierup, M H & Kaessmann, H 2023, ' The molecular evolution of spermatogenesis across mammals ', Nature .
Murat, F, Mbengue, N, Winge, S B, Trefzer, T, Leushkin, E, Sepp, M, Cardoso-Moreira, M, Schmidt, J, Schneider, C, Mößinger, K, Brüning, T, Lamanna, F, Belles, M R, Conrad, C, Kondova, I, Bontrop, R, Behr, R, Khaitovich, P, Pääbo, S, Marques-Bonet, T, Grützner, F, Almstrup, K, Schierup, M H & Kaessmann, H 2023, ' The molecular evolution of spermatogenesis across mammals ', Nature, vol. 613, pp. 308–316 . https://doi.org/10.1038/s41586-022-05547-7
Nature, 613. Nature Research
Nature

مصطلحات موضوعية: Male, [SDV]Life Sciences [q-bio], Gene Expression, Cell-adhesion, 0302 clinical medicine, Ecology,Evolution & Ethology, Origins, Sex-chromosomes, Features, X chromosome, X-chromosome, 0303 health sciences, Spermatogenic Cell, Human Biology & Physiology, Multidisciplinary, Chromatin/genetics, Sertoli cell, Gene expression profiling, Dynamics, Chromatin, medicine.anatomical_structure, Sexual selection, Genetics & Genomics, Macaque, Model organisms, Evolution, Mammals/genetics, Biology, Chromosomes, Evolutionary genetics, Evolution, Molecular, 03 medical and health sciences, Meiosis, Molecular evolution, medicine, Animals, mammals, General, 030304 developmental biology, Computational & Systems Biology, Spermatogenesis/genetics, Molecular, Chromosome, Evolutionary pressure, spermatogenesis, Genes, Meiosis/genetics, Evolutionary biology, Testis/metabolism, 030217 neurology & neurosurgery, Developmental Biology

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c5b94a7cb3b0894be247c9cbeae7eff

المؤلفون: Margo Willems, Catharina Olsen, Ben Caljon, Veerle Vloeberghs, Jean De Schepper, Herman Tournaye, Dorien Van Saen, Ellen Goossens

المساهمون: Brussels Heritage Lab, Basic (bio-) Medical Sciences, Biology of the Testis, Clinical sciences, Medical Genetics, Centre for Reproductive Medicine - Gynaecology, Mental Health and Wellbeing research group, UZB Other, Surgical clinical sciences

المصدر: Scientific Reports. 12

مصطلحات موضوعية: Male, Klinefelter Syndrome/pathology, Multidisciplinary, fibrosis, Obstetrics and Gynaecology, Testis/metabolism, Humans, Transcriptome, RNA/metabolism, Atrophy/pathology, reproductive medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a3bb974d7b1188b05e58313c3fe158b
https://doi.org/10.1038/s41598-022-26011-6

المؤلفون: Maurizy, Chloé, Quinternet, Marc, Abel, Yoann, Verheggen, Céline, Santo, Paulo E., Bourguet, Maxime, Paiva, Ana C. F., Bragantini, Benoît, Chagot, Marie-Eve, Robert, Marie-Cécile, Abeza, Claire, Fabre, Philippe, Fort, Philippe, Vandermoere, Franck, Sousa, Pedro M. F., Rain, Jean-Christophe, Charpentier, Bruno, Cianférani, Sarah, Bandeiras, Tiago M., Pradet-Balade, Bérengère, Manival, Xavier, Bertrand, Edouard

المصدر: Nature Communications, 9 (1), 2093 (2018)

مصطلحات موضوعية: ATPases Associated with Diverse Cellular Activities/metabolism, Adaptor Proteins, Signal Transducing/metabolism, Antigens, Surface/metabolism, Apoptosis Regulatory Proteins/genetics/metabolism, Carrier Proteins/genetics/metabolism, Cell Line, DNA Helicases/metabolism, GTP-Binding Proteins/metabolism, HEK293 Cells, HSP90 Heat-Shock Proteins/metabolism, HeLa Cells, Humans, Male, Membrane Proteins/metabolism, Molecular Chaperones/metabolism, Protein Binding, Protein Folding, Protein Structure, Secondary, Signal Transduction, Testis/metabolism, Life sciences, Biochemistry, biophysics & molecular biology, Sciences du vivant, Biochimie, biophysique & biologie moléculaire

Relation: urn:issn:2041-1723

URL الوصول: https://orbi.uliege.be/handle/2268/259801

المؤلفون: Alejo Torres-Cano, Rosa Portella-Fortuny, Claudia Müller-Sánchez, Sonia Porras-Marfil, Marina Ramiro-Pareta, You-Ying Chau, Manuel Reina, Francesc X. Soriano, Ofelia M. Martínez-Estrada

المصدر: Torres-Cano, A, Portella-Fortuny, R, Müller-Sánchez, C, Porras-Marfil, S, Ramiro-Pareta, M, Chau, Y-Y, Reina, M, Soriano, F X & Martínez-Estrada, O M 2022, ' Deletion of Wt1 during early gonadogenesis leads to differences of sex development in male and female adult mice ', PLoS Genetics, vol. 18, no. 6, e1010240 . https://doi.org/10.1371/journal.pgen.1010240

مصطلحات موضوعية: Male, Cancer Research, Sex Differentiation/genetics, Sex Differentiation, Sexual Development, Ovary, Cell Differentiation/genetics, Ovary/metabolism, Cell Differentiation, Gonads/metabolism, WT1 Proteins/genetics, Mice, Testis, Genetics, Testis/metabolism, Animals, Female, Gonads, WT1 Proteins, Molecular Biology, Genetics (clinical), Ecology, Evolution, Behavior and Systematics

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db39658a71f71b957dada7aa02d16478
https://www.pure.ed.ac.uk/ws/files/293752226/journal.pgen.1010240.pdf

المؤلفون: Nino Sincic, Ana Katusic Bojanac, Floriana Bulic-Jakus, Dajana Krsnik, Tihana Maric

المصدر: International journal of molecular sciences. 23(13)

مصطلحات موضوعية: Male, Spermatogonia / metabolism, Aging, Organic Chemistry, Fertility / genetics, General Medicine, Catalysis, Spermatogonia, Computer Science Applications, Testis / metabolism, Inorganic Chemistry, Fertility, Klinefelter Syndrome, Testicular Neoplasms, LIN28A, LIN28B, cancer, infertility, testis, Aging / genetics, Testis, Humans, Testicular Neoplasms / metabolism, Physical and Theoretical Chemistry, Klinefelter Syndrome / metabolism, Molecular Biology, Spectroscopy

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb7edf4cb2fd82685d4f206c4dd3e7b5
https://pubmed.ncbi.nlm.nih.gov/35806250

المؤلفون: Danyang Wang, Simone Hildorf, Elissavet Ntemou, Linn Salto Mamsen, Lihua Dong, Susanne Elisabeth Pors, Jens Fedder, Erik Clasen-Linde, Dina Cortes, Jørgen Thorup, Claus Yding Andersen

المساهمون: Basic (bio-) Medical Sciences

المصدر: Wang, D, Hildorf, S, Ntemou, E, Mamsen, L S, Dong, L, Pors, S E, Fedder, J, Clasen-Linde, E, Cortes, D, Thorup, J & Andersen, C Y 2022, ' Organotypic Culture of Testicular Tissue from Infant Boys with Cryptorchidism ', International Journal of Molecular Sciences, vol. 23, no. 14, 7975 . https://doi.org/10.3390/ijms23147975
International Journal of Molecular Sciences; Volume 23; Issue 14; Pages: 7975

مصطلحات موضوعية: Male, Sertoli Cells, Organic Chemistry, Infant, human immature testicular tissue, cryptorchidism, infertility, organotypic culture, fertility preservation, testicular tissue cryopreservation, General Medicine, Spermatogonia, Catalysis, Computer Science Applications, Inorganic Chemistry, Spermatogonia/metabolism, Cryptorchidism, Testis, Testis/metabolism, Humans, Spermatogenesis/physiology, Physical and Theoretical Chemistry, Spermatogenesis, Molecular Biology, Sertoli Cells/metabolism, Spectroscopy, Cryptorchidism/metabolism

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f02bf2bf53cb60a7fcac428d3223baf5
https://curis.ku.dk/ws/files/315532771/ijms_23_07975_v2.pdf

المؤلفون: Danyang Wang, Simone Hildorf, Elissavet Ntemou, Lihua Dong, Susanne Elisabeth Pors, Linn Salto Mamsen, Jens Fedder, Eva R. Hoffmann, Erik Clasen-Linde, Dina Cortes, Jørgen Thorup, Claus Yding Andersen

المساهمون: Basic (bio-) Medical Sciences

المصدر: Wang, D, Hildorf, S, Ntemou, E, Dong, L, Pors, S E, Mamsen, L S, Fedder, J, Hoffmann, E R, Clasen-Linde, E, Cortes, D, Thorup, J & Andersen, C Y 2022, ' Characterization and Survival of Human Infant Testicular Cells After Direct Xenotransplantation ', Frontiers in Endocrinology, vol. 13, pp. 853482 . https://doi.org/10.3389/fendo.2022.853482
Wang, D, Hildorf, S, Ntemou, E, Dong, L, Pors, S E, Mamsen, L S, Fedder, J, Hoffmann, E R, Clasen-Linde, E, Cortes, D, Thorup, J & Andersen, C Y 2022, ' Characterization and Survival of Human Infant Testicular Cells After Direct Xenotransplantation ', Frontiers in Endocrinology, vol. 13, 853482 . https://doi.org/10.3389/fendo.2022.853482

مصطلحات موضوعية: Cryopreservation, Male, cryptorchid, endocrine system, gonocyte, Endocrinology, Diabetes and Metabolism, Transplantation, Heterologous, Spermatozoa, spermatogonial stem cell, Spermatogonia, spermatogonia, immature testis, Mice, Spermatogonia/metabolism, Testis, Testis/metabolism, Animals, Humans, infertility, transplantation

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc055f92ea7287e7f913622ba27bf309
https://curis.ku.dk/portal/da/publications/characterization-and-survival-of-human-infant-testicular-cells-after-direct-xenotransplantation(94ac4b1c-b3cb-4b62-a355-f6ea2bd991cc).html

المؤلفون: Wiwat Rodprasert, Jaakko J Koskenniemi, Helena E Virtanen, Sergey Sadov, Antti Perheentupa, Helena Ollila, Jakob Albrethsen, Anna-Maria Andersson, Anders Juul, Niels E Skakkebaek, Katharina M Main, Jorma Toppari

المصدر: Rodprasert, W, Koskenniemi, J J, Virtanen, H E, Sadov, S, Perheentupa, A, Ollila, H, Albrethsen, J, Andersson, A-M, Juul, A, Skakkebaek, N E, Main, K M & Toppari, J 2022, ' Reproductive Markers of Testicular Function and Size During Puberty in Boys With and Without a History of Cryptorchidism ', The Journal of clinical endocrinology and metabolism, vol. 107, no. 12, pp. 3353-3361 . https://doi.org/10.1210/clinem/dgac520

مصطلحات موضوعية: Male, Endocrinology, Diabetes and Metabolism, Biochemistry (medical), Clinical Biochemistry, Puberty, Biochemistry, Endocrinology, Case-Control Studies, Testis, Cryptorchidism, Testis/metabolism, Humans, Inhibins, Prospective Studies, Insulin-Like Growth Factor I, Follicle Stimulating Hormone, Biomarkers

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a492464749a917841dc010a9008edeb
https://curis.ku.dk/portal/da/publications/reproductive-markers-of-testicular-function-and-size-during-puberty-in-boys-with-and-without-a-history-of-cryptorchidism(56ec2498-357b-48ed-b691-e081874cf24a).html

المؤلفون: Silvia Corrochano, Abigail Harris, Hans Clevers, Caroline Eozenou, Isabelle Stévant, Joelle Bignon-Topalovic, Nick Warr, Neila Belguith, Sara Wells, Bochra Ben Rhouma, Pam Siggers, Serge Nef, Daniel T. Grimes, Ken McElreavey, Rebecca D. Burdine, Feng Cong, Makoto Suzuki, Andy Greenfield, Danielle Sagar, Anu Bashamboo, Bon-Kyoung Koo, Raja Brauner

المساهمون: Medical Research Coucil Harwell [Oxford, UK] (MRC Harwell), MRC Harwell, Department of Molecular Biology [Princeton], Princeton University, Novartis Institutes for BioMedical Research (NIBR), Hubrecht Institute [Utrecht, Netherlands], University Medical Center [Utrecht]-Royal Netherlands Academy of Arts and Sciences (KNAW), Université de Genève = University of Geneva (UNIGE), Fondation Ophtalmologique Adolphe de Rothschild [Paris], Université Paris Descartes - Paris 5 (UPD5), Faculté de médecine - Faculty of Medicine [Sfax, Tunisie] (FMS), Université de Sfax - University of Sfax, Génétique du Développement humain - Human developmental genetics, Institut Pasteur [Paris] (IP), This work was supported by the Medical Research Council by core funding Grant MC_U142684167 (to A.G.) at the Harwell Institute, and the Agence Nationale de la Recherche Grant ANR-10-LABX-73 (to K.M.). S.N. acknowledges support from Swiss National Science Foundation Grant 31003A_173070. M.S. was a visiting scientist supported by the Strategic International Research Exchange Program between Princeton University and National Institutes of Natural Sciences, Japan. D.T.G. was supported by National Institute of Arthritis and Mucoskeletal and Skin Diseases Pathway to Independence Award 1K99AR070905. Work in the R.D.B. laboratory is supported by the National Institute of Child Health and Development Grant 2R01HD048584., We thank the husbandry team in Ward 5 of the Mary Lyon Centre at Harwell and the Frozen Embryo and Sperm Archive (FESA) and histology teams. We thank Dagmar Wilhelm for the kind gift of anti-FOXL2 antibody. We thank Phil Johnson for zebrafish husbandry. We acknowledge European Cooperation in Science & Technology (COST) Action BM1303 (DSDnet)., ANR-10-LABX-0073,REVIVE,Stem Cells in Regenerative Biology and Medicine(2010), Université de Genève (UNIGE), Génétique du développement humain, Institut Pasteur [Paris], Hubrecht Institute for Developmental Biology and Stem Cell Research

المصدر: Proceedings of the National Academy of Sciences, Vol. 115, No 21 (2018) pp. 5474-5479
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, 2018, 115 (21), pp.5474-5479. ⟨10.1073/pnas.1801223115⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2018, 115 (21), pp.5474-5479. ⟨10.1073/pnas.1801223115⟩
Proceedings of the National Academy of Sciences of the United States of America, 115(21), 5474
Proceedings of the National Academy of Sciences of the United States of America, 115(21), 5474-5479. National Academy of Sciences

مصطلحات موضوعية: 0301 basic medicine, Male, Embryo, Nonmammalian, Sex Differentiation, Organogenesis, Wnt Proteins/antagonists & inhibitors, Disorders of Sex Development, DSD, MESH: Wnt Proteins / metabolism, MESH: Testis / metabolism, MESH: Disorders of Sex Development / genetics, MESH: Testis / pathology, MESH: Embryo, Nonmammalian / cytology, Mice, Embryo, Nonmammalian/cytology, MESH: Gene Expression Regulation, Developmental, Testis, Missense mutation, MESH: Animals, ddc:576.5, Developmental, Disorders of sex development, 10. No inequality, MESH: Ubiquitin-Protein Ligases / genetics, Exome sequencing, Cells, Cultured, beta Catenin, Zebrafish, Multidisciplinary, Cultured, MESH: Thrombospondins / genetics, MESH: SOX9 Transcription Factor / metabolism, Wnt signaling pathway, Gene Expression Regulation, Developmental, SOX9 Transcription Factor, beta Catenin/antagonists & inhibitors, MESH: beta Catenin / metabolism, Sex reversal, MESH: Gonads / pathology, Cell biology, MESH: Young Adult, Embryo, MESH: Gonads / metabolism, Female, MESH: Cells, Cultured, Adult, Adolescent, Ubiquitin-Protein Ligases, Cells, Thrombospondins/genetics, Mutation, Missense, MESH: beta Catenin / antagonists & inhibitors, SOX9, Biology, Gonads/metabolism, MESH: Embryo, Nonmammalian / metabolism, 03 medical and health sciences, Young Adult, MESH: Wnt Proteins / genetics, WNT signaling, medicine, Animals, Humans, Ubiquitin-Protein Ligases/genetics, MESH: SOX9 Transcription Factor / genetics, MESH: Zebrafish, RSPO1, Gonads, General, MESH: Mice, Nonmammalian/cytology, MESH: Disorders of Sex Development / pathology, MESH: Adolescent, MESH: Wnt Proteins / antagonists & inhibitors, MESH: Mutation, Missense, MESH: Humans, MESH: beta Catenin / genetics, ZNRF3, MESH: Adult, Sex determination, medicine.disease, MESH: Male, MESH: Ubiquitin-Protein Ligases / physiology, SOX9 Transcription Factor/genetics, Wnt Proteins, 030104 developmental biology, MESH: Thrombospondins / metabolism, [SDV.GEN.GH]Life Sciences [q-bio]/Genetics/Human genetics, Gene Expression Regulation, Mutation, Testis/metabolism, Missense, Thrombospondins, MESH: Female, Function (biology), Disorders of Sex Development/genetics, MESH: Sex Differentiation

وصف الملف: image/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f785b7c346bbb98027161ca7382405e7
https://hdl.handle.net/20.500.11755/a85a814a-a5a7-4064-9ca8-516f15a8bb58

المؤلفون: Anders Juul, Klaus Brasso, Hanne Frederiksen, Martin Blomberg Jensen, John E. Nielsen, Hein Vincent Stroomberg, Anne Jørgensen, Martin Andreas Røder

المصدر: PLoS ONE, Vol 15, Iss 9, p e0238814 (2020)
PLoS ONE
Stroomberg, H V, Jørgensen, A, Brasso, K, Nielsen, J E, Juul, A, Frederiksen, H, Blomberg Jensen, M & Røder, M A 2020, ' Novel functions of the luteinizing hormone/chorionic gonadotropin receptor in prostate cancer cells and patients ', PLoS ONE, vol. 15, no. 9, e0238814 . https://doi.org/10.1371/journal.pone.0238814

مصطلحات موضوعية: Male, Prostate/pathology, Epidemiology, Cancer Treatment, Pilot Projects, Receptors, LH/metabolism, urologic and male genital diseases, Chorionic Gonadotropin, Metastasis, Prostate cancer, 0302 clinical medicine, Basic Cancer Research, Testis, Medicine and Health Sciences, Tumor Cells, Cultured, Testosterone, Reproductive System Procedures, Receptor, DU145 cells, 030219 obstetrics & reproductive medicine, Multidisciplinary, Organic Compounds, Prostate Cancer, Cancer Risk Factors, Prostate Diseases, Prostate, Middle Aged, Receptors, LH, Testosterone/metabolism, Chemistry, Luteinization, Oncology, 030220 oncology & carcinogenesis, Physical Sciences, Cell lines, Medicine, Steroids, Luteinizing Hormone/metabolism, Anatomy, Luteinizing hormone, Biological cultures, Research Article, medicine.medical_specialty, endocrine system, Urology, Science, Surgical and Invasive Medical Procedures, Luteinization/drug effects, 03 medical and health sciences, Exocrine Glands, DU145, Internal medicine, LNCaP, medicine, Humans, Castration, Aged, Prostatectomy, Cell growth, business.industry, Prostatic Neoplasms/physiopathology, Organic Chemistry, Prostatectomy/adverse effects, Chemical Compounds, Cancers and Neoplasms, Biology and Life Sciences, Prostatic Neoplasms, Luteinizing Hormone, medicine.disease, Research and analysis methods, Genitourinary Tract Tumors, Endocrinology, Medical Risk Factors, Testis/metabolism, Chorionic Gonadotropin/pharmacology, Prostate Gland, business

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73a5f4dfd59dfe138d616c1abcb1d5cc
https://doaj.org/article/c14d32fadb2441119a34e5df62822512