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1دورية أكاديمية
المؤلفون: Hideyuki Kurata, Tetsuya Ishino, Yasuhiro Ohshima, Masafumi Yohda
المصدر: Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
مصطلحات موضوعية: CDMO, biologics, bioprocess, monoclonal antibody, semiconductor, foundry, Biotechnology, TP248.13-248.65
وصف الملف: electronic resource
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المؤلفون: Hideyuki Kurata, Tetsuya Ishino, Yasuhiro Ohshima, Masafumi Yohda
المصدر: Frontiers in bioengineering and biotechnology. 10
مصطلحات موضوعية: Histology, Biomedical Engineering, Bioengineering, Biotechnology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c20536352eba8b3f1370d43aa8eb892
https://pubmed.ncbi.nlm.nih.gov/35387299 -
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المؤلفون: Jing Zhou, Khetemenee Lam, Romer A. Gonzalez-Villalobos, John J. Scarcelli, Eric Sousa, Yan Weng, Ron Kriz, Tetsuya Ishino, Darren Ferguson, Yan Zhang, Hongli L. Zhu, Boriana Tzvetkova, Valerie Clerin, Mellisa Ly, Alan C. Opsahl, Xiaotian Zhong, Qing Yao, Kim F. McClure, Kaffa Cote, Aaron M. D’Antona, Justin Cohen, Laura Lin, Annette Sievers, Weili Duan, James R. Apgar, Jason C. Rouse, Srinath Jagarlapudi, Joe Palandra, Keith A. Johnson, Suma Yaddanapudi, Richard Zollner
المصدر: J Biol Chem
مصطلحات موضوعية: 0301 basic medicine, Fibroblast growth factor 23, CHO Cells, urologic and male genital diseases, Biochemistry, Mass Spectrometry, 03 medical and health sciences, Structure-Activity Relationship, Cricetulus, Catalytic Domain, Cricetinae, medicine, Animals, Humans, Renal Insufficiency, Chronic, Molecular Biology, Klotho, Klotho Proteins, Chromatography, High Pressure Liquid, Glucuronidase, Kidney, 030102 biochemistry & molecular biology, Chemistry, Chinese hamster ovary cell, HEK 293 cells, Glycopeptides, Cell Biology, medicine.disease, Recombinant Proteins, Cell biology, Rats, Fibroblast Growth Factor-23, 030104 developmental biology, medicine.anatomical_structure, HEK293 Cells, Membrane protein, Reperfusion Injury, Protein Structure and Folding, Mutagenesis, Site-Directed, Signal transduction, Protein Processing, Post-Translational, Kidney disease, Glomerular Filtration Rate, Half-Life
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2aa95052a8ec3a97f4bd0138f1cc2d5
https://pubmed.ncbi.nlm.nih.gov/32005658 -
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المؤلفون: Denise O'Hara, William S. Somers, Ron Kriz, Saswata Talukdar, Jeffrey R. Chabot, Eric Sousa, Annette Sievers, Alison Joyce, Yingjiang Zhou, Jie Guo, Barbara Bernardo, Dongmei Li, Craig Giragossian, Alison Logan, Amy Tam, Roberto A. Calle, Mania Kavosi, Tracey Clark, Laura Lin, Tetsuya Ishino, Darwin V. Lee, Weili Duan, Kelvin M. Kerns, Mark Stahl, Yan Weng, Tao He
المصدر: Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-15 (2018)مصطلحات موضوعية: 0301 basic medicine, FGF21, Glycosylation, medicine.drug_class, Metabolic Clearance Rate, medicine.medical_treatment, Injections, Subcutaneous, lcsh:Medicine, CHO Cells, Pharmacology, Monoclonal antibody, Article, 03 medical and health sciences, Mice, 0302 clinical medicine, Cricetulus, Pharmacokinetics, Cricetinae, Medicine, Animals, Humans, Tissue Distribution, Dosing, lcsh:Science, Multidisciplinary, Protease, medicine.diagnostic_test, business.industry, Protein Stability, Chinese hamster ovary cell, lcsh:R, Fibroblast Growth Factors, Macaca fascicularis, 030104 developmental biology, Long acting, HEK293 Cells, 030220 oncology & carcinogenesis, Proteolysis, lcsh:Q, business, Lipid profile
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المؤلفون: Laura Lin, Tetsuya Ishino, Weili Duan, Ronald Kriz, Amy Tam, Denise O'Hara, Mengmeng Wang, William S. Somers, Alison Joyce
المصدر: Journal of Bioscience and Bioengineering. 119:657-660
مصطلحات موضوعية: Glycan, Glycosylation, Receptors, Cell Surface, Bioengineering, CHO Cells, macromolecular substances, Applied Microbiology and Biotechnology, Antibodies, Mannans, chemistry.chemical_compound, Cricetulus, In vivo, Cricetinae, Animals, Humans, Lectins, C-Type, biology, Chinese hamster ovary cell, HEK 293 cells, Molecular biology, In vitro, Kinetics, HEK293 Cells, Mannose-Binding Lectins, chemistry, Antibody Formation, biology.protein, Antibody, Mannose Receptor, Mannose receptor, Biotechnology
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المصدر: Pharmaceutical Research. 28:2412-2421
مصطلحات موضوعية: Male, Nitrilotriacetic Acid, Pharmaceutical Science, PEGylation, Protein delivery, Chromatography, Affinity, Protein Structure, Secondary, Polyethylene Glycols, Rats, Sprague-Dawley, chemistry.chemical_compound, Drug Delivery Systems, Protein structure, Affinity chromatography, Coordination Complexes, Granulocyte Colony-Stimulating Factor, PEG ratio, Animals, Organic chemistry, Histidine, Pharmacology (medical), Chelation, Protein secondary structure, Chelating Agents, Pharmacology, Bioconjugation, Organic Chemistry, Nitrilotriacetic acid, Proteins, Surface Plasmon Resonance, Combinatorial chemistry, Rats, chemistry, Molecular Medicine, Protein Binding, Biotechnology
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المؤلفون: Tetsuya Ishino, Meirav Zaks-Zilberman, Jeffery J. Scibek, Adrian E. Harrington, Irwin Chaiken
المصدر: Cytokine. 42:179-190
مصطلحات موضوعية: Protein subunit, Immunology, Interleukin 5 receptor alpha subunit, Biology, Biochemistry, Article, Cell Line, Cytokine Receptor Common beta Subunit, Interleukin-5 Receptor alpha Subunit, Animals, Humans, Immunology and Allergy, Cytokine binding, Receptor, Molecular Biology, GM-CSF Receptor, Granulocyte-Macrophage Colony-Stimulating Factor, Hematology, Receptors, Interleukin-5, Receptors, Granulocyte-Macrophage Colony-Stimulating Factor, Biophysics, Drosophila, Interleukin-5, Signal transduction, Cytokine receptor, Signal Transduction
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المصدر: Journal of Biological Chemistry. 283:13398-13406
مصطلحات موضوعية: Models, Molecular, Yellow fluorescent protein, Time Factors, Protein subunit, Interleukin 5 receptor alpha subunit, Gene Expression, Biology, Crystallography, X-Ray, Biochemistry, Cell Line, Cytokine Receptor Common beta Subunit, Interleukin 10 receptor, alpha subunit, Interleukin-5 Receptor alpha Subunit, Fluorescence Resonance Energy Transfer, Humans, Transgenes, Molecular Biology, Interleukin-5 receptor, Mechanisms of Signal Transduction, Cell Biology, Ligand (biochemistry), Molecular biology, Protein Structure, Tertiary, Förster resonance energy transfer, Mutation, Biophysics, biology.protein, Interleukin-5, Protein Binding
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64a663ef39d2ca8b05552176126eda92
https://doi.org/10.1074/jbc.m710230200 -
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المؤلفون: Hosahudya N. Gopi, Adrian E. Harrington, Tetsuya Ishino, Irwin Chaiken
المصدر: Current Pharmaceutical Design. 14:1231-1239
مصطلحات موضوعية: Pharmacology, Receptor Activation Process, Interleukin-5 receptor, Binding Sites, Protein Conformation, Interleukin 5 receptor alpha subunit, Antibodies, Monoclonal, Biology, Peptides, Cyclic, Eosinophils, Interleukin-5 Receptor alpha Subunit, Interleukin-21 receptor, Eosinophilia, Drug Discovery, Immunology, Interleukin-6 receptor, Cancer research, Animals, Humans, Interleukin-5, Interleukin 5, Interleukin 12 receptor, beta 1 subunit, Common gamma chain
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المؤلفون: Jun Kuai, Lidia Mosyak, Michael Cain, Robert Arch, Nicholas Pullen, Gregory J. Carven, Shinji Ogawa, Jon Brooks, Dirk Ponsel, Zhiyong Yang, Robert Rauchenberger, Edward R. Lavallie, Tetsuya Ishino, May Tam
المصدر: Biochemistry. 54(10)
مصطلحات موضوعية: biology, Chemistry, Cell growth, Becaplermin, Antibodies, Monoclonal, Proto-Oncogene Proteins c-sis, Ligand (biochemistry), Biochemistry, Molecular biology, Antibodies, Neutralizing, Cell biology, Receptor, Platelet-Derived Growth Factor beta, Mitogen-activated protein kinase, biology.protein, Humans, Avidity, Binding Sites, Antibody, Binding site, Receptor, Tyrosine kinase, Platelet-derived growth factor receptor, Aptamers, Peptide, Cells, Cultured, Cell Proliferation