نتائج البحث - "Th2 Cells metabolism"

1

رسالة جامعية

Studies of Mucosal Immune Regulation in Celiac Disease and Type 1 Diabetes

URL الوصول: http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-110687

Degree: Diss. (sammanfattning) Linköping : Linköpings universitet, 2014

2

Double Positive CD4+CD8+ T Cells Are Enriched in Urological Cancers and Favor T Helper-2 Polarization

المؤلفون: Denise Nardelli-Haefliger, Ilaria Lucca, Massimo Valerio, Patrice Jichlinski, Sonia-Christina Rodrigues-Dias, Laurent Derré, Rodolfo Burruni, Florence Dartiguenave, Thomas Tawadros, Valérie Cesson, Perrine Bohner, Mathieu F. Chevalier

المساهمون: Lausanne University Hospital, Lausanne university hospital

المصدر: Frontiers in Immunology
Frontiers in Immunology, Frontiers, 2019, 10, ⟨10.3389/fimmu.2019.00622⟩
Frontiers in Immunology, Vol 10 (2019)
Frontiers in immunology, vol. 10, pp. 622

مصطلحات موضوعية: Male, lcsh:Immunologic diseases. Allergy, 0301 basic medicine, Aged, Aged, 80 and over, CD4 Antigens/blood, CD4 Antigens/immunology, CD8 Antigens/blood, CD8 Antigens/immunology, Female, Flow Cytometry, Humans, Kidney Neoplasms/blood, Kidney Neoplasms/immunology, Kidney Neoplasms/pathology, Middle Aged, Prostatic Neoplasms/blood, Prostatic Neoplasms/immunology, Prostatic Neoplasms/pathology, Th2 Cells/immunology, Th2 Cells/metabolism, Th2 Cells/pathology, Urinary Bladder Neoplasms/blood, Urinary Bladder Neoplasms/immunology, Urinary Bladder Neoplasms/pathology, CD4+CD8+ T cells, Th1, Th2, bladder cancer, double positive T cells, kidney cancer, prostate cancer, CD8 Antigens, Immunology, Double negative, Context (language use), Biology, Flow cytometry, 03 medical and health sciences, Prostate cancer, Th2 Cells, 0302 clinical medicine, Immune system, medicine, Immunology and Allergy, Cytotoxic T cell, Original Research, medicine.diagnostic_test, Prostatic Neoplasms, Cancer, medicine.disease, Kidney Neoplasms, 3. Good health, 030104 developmental biology, Urinary Bladder Neoplasms, CD4 Antigens, Cancer research, [SDV.IMM]Life Sciences [q-bio]/Immunology, CD4 + CD8 + T cells, lcsh:RC581-607, CD8, 030215 immunology

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f34716cc65e1b6de45583df3a05f67e
https://hal.archives-ouvertes.fr/hal-03031633/document

3

A recessive form of hyper-IgE syndrome by disruption of ZNF341-dependent STAT3 transcription and activity

المؤلفون: Warren J. Leonard, Nima Rezaei, Kathryn Payne, Isabelle Meyts, Laurent Abel, Cindy S. Ma, Marianne Leruez-Ville, Janet Chou, Alain Hovnanian, Jian-Xin Lin, Simon J. Pelham, Danielle T. Avery, Matthieu Bouaziz, Bethany Pillay, Tanwir Habib, Anne Puel, Sevgi Keles, Juan Li, Isabelle Pellier, Jamel El-Benna, Bernhard Fleckenstein, Ahmet Ozen, Vivien Béziat, Ingrid Müller-Fleckenstein, Damien Chaussabel, Samaneh Zoghi, Yi Wang, Paul Gray, Matthias Titeux, Yoann Zerbib, Talal A. Chatila, Marie-Alexandra Alyanakian, Capucine Picard, Orli Wargon, Ayper Somer, Marie-Olivia Chandesris, Thibaut Leclercq, Ibtihal Benhsaien, Aziz Belkadi, Jean-Laurent Casanova, Romain Lévy, Peng Li, Geetha Rao, Ai Ing Lim, James P. Di Santo, Nico Marr, Sylvie Fraitag, Frédégonde About, Elissa K. Deenick, Bertrand Boisson, Jacinta Bustamante, Mélanie Migaud, Bodo Grimbacher, Aziz Bousfiha, Fatima Ailal, Safa Baris, Antoine Guérin, Stuart G. Tangye, Romain Guery, Ning Du, Vimel Rattina

المساهمون: Imagine - Institut des maladies génétiques (IMAGINE - U1163), Centre National de la Recherche Scientifique (CNRS)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), Rockefeller University [New York], National Institutes of Health [Bethesda] (NIH), Garvan Institute of Medical Research [Darlinghurst, Australia], University of New South Wales [Sydney] (UNSW), CHU Ibn Rochd [Casablanca], Université Hassan II [Casablanca] (UH2MC), Service d'Immuno-Hémato-Oncologie Pédiatrique, Centre Hospitalier Universitaire d'Angers (CHU Angers), PRES Université Nantes Angers Le Mans (UNAM)-PRES Université Nantes Angers Le Mans (UNAM), Shahid Beheshti University of Medical Sciences [Tehran] (SBUMS), Shahid Beheshti University, Universal Scientific Education and Research Network (USERN), Marmara University [Kadıköy - İstanbul], Necmettin Erbakan University [Konya, Turquie], Immunité Innée, Institut Pasteur [Paris]-Institut National de la Santé et de la Recherche Médicale (INSERM), Harvard Medical School [Boston] (HMS), Boston Children's Hospital, Centre d'infectiologie Necker-Pasteur [CHU Necker], CHU Necker - Enfants Malades [AP-HP], Sidra Medicine, Centre de recherche sur l'Inflammation (CRI (UMR_S_1149 / ERL_8252 / U1149)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7), Freiburg University Medical Center, Sydney children's hospital, Centre de Référence Déficits Immunitaires Héréditaires (CEREDIH), Assistance publique - Hôpitaux de Paris (AP-HP) (APHP)-CHU Necker - Enfants Malades [AP-HP], Friedrich-Alexander Universität Erlangen-Nürnberg (FAU), Genetic skin diseases : from disease mechanism to therapies (Equipe Inserm U1163), Centre National de la Recherche Scientifique (CNRS)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), Service de pathologie [CHU Necker], Service d'immuno-hématologie pédiatrique [CHU Necker], Laboratoire de Virologie [CHU Necker], Université Paris Descartes - Paris 5 (UPD5), Centre d'étude des Déficits Immunitaires, University Hospitals Leuven [Leuven], Catholic University of Leuven - Katholieke Universiteit Leuven (KU Leuven), Istanbul University, Research Center for Immunodeficiencies [Tehran, Iran], Tehran University of Medical Sciences (TUMS), University of New South Wales [Canberra Campus] (UNSW), Howard Hughes Medical Institute [New York], New York University School of Medicine, NYU System (NYU)-NYU System (NYU)-Rockefeller University [New York]-Columbia University Irving Medical Center (CUIMC), This work was supported by grants from INSERM, Paris Descartes University, Laboratoire d’Excellence Integrative Biology of Emerging Infectious Diseases (ANR-10-LABX-62-IBEID), the Jeffrey Modell Foundation Translational Research Program, the French National Research Agency (ANR, grant nos. GENCMCD-ANR-11-BSV3–005-01, HGDIFD-ANR-14-CE15-0006-01, NKIR-ANR-13-PDOC-0025-01, and EURO-CMC-ANR-14-RARE-0005-02), and grants awarded under the 'Investissement d’avenir' program (grant no. ANR-10-IAHU-01), the National Institute of Allergy and Infectious Diseases of the NIH (grant nos. U01AI109697 and R01AI127564), the Rockefeller University, the Howard Hughes Medical Institute, the St. Giles Foundation, the Institut Pasteur, and FP7, under grant agreements 305578 (PathCO) and 317057 (HOMIN). We thank the Centre de Recherche Translationnelle (Institut Pasteur) for technical assistance. V.B. is supported by the ANR (grant no. NKIR-ANR-13-PDOC-0025-01). R.L. is supported by the INSERM Ph.D. program (Poste d’Accueil INSERM), a Fulbright grant (Franco-American commission), and a Philippe Foundation scholarship. Y.Z. received the 'médaille d’or du Centre Hospitalier Universitaire d’Amiens.' Y.W. is supported by the French National Agency for Research on AIDS and Viral Hepatitis (ANRS, grant no. 13318). F. About holds a fellowship from Fondation pour la Recherche Médicale (FRM, grant no. FDM20140630671). A.G. is supported by an IFNGPHOX grant (no. ANR13-ISV3-0001-01) from ANR. B.G. was funded by BMBF (German Federal Ministry of Education and Research) grants 01E01303 and 01ZX1306F. I.M. is supported by a klinische onderzoeks-en opleidingsraad (clinical research council) grant from UZ Leuven, a klinisch onderzoeksfonds (clinical research fund) grant from KU Leuven, and an International Mobility Grant from Fonds voor Wetenschappelijk Onderzoek (fund for scientific research) Vlaanderen. C.S.M., E.K.D., and S.G.T. are supported by grants and fellowships from the National Health and Medical Research Council of Australia. C.S.M., P.G., E.K.D., and S.G.T. are members of CIRCA (Clinical Immunogenomics Research Consortia Australia), which is funded by the Office of Health and Medical Research of the NSW Government, the Jeffrey Modell Foundation, and the John Cook Brown Foundation. A.I.L. is a scholar of the Pasteur-Paris University International Ph.D. program and is supported by a Ph.D. International Training Network grant from the European Union’s Seventh Framework Program under grant agreement no. 317057 (HOMIN). T.A.C. was supported by a grant from the National Institute of Allergy and Infectious Diseases of the NIH (5R01AI065617). S.K. was supported by a grant from the Scientific and Technological Research Council of Turkey (1059B191300622). J.-X.L., P.L., N.D., and W.J.L. were supported by the Division of Intramural Research, National Heart, Lung, and Blood Institute, NIH. A.P. was supported by an AP-HP interface contract., We thank the patients and their families for participating in this study. We thank J. E. Darnell and C. Mertens for advice and for providing reagents. We thank the members of the laboratory, especially F. Jabot-Hanin and V. Pedergnana, for their valuable input on linkage analysis, L. Amar, Y. Nemirovskaya, D. Papandrea, E. Anderson, M. Woollett, C. Desvallées, C. Patissier, and M. Corrias for administrative assistance, E. Jouanguy and Y. Itan for helpful discussions, S. Boucherit for clinical data collection, S. Jacques and the Cochin genomics platform for microarray experiments, and N. Goudin and R. Desveaux of the Necker Institute Imaging Facility., Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), Garvan Institute of medical research, Immunité Innée - Innate Immunity, Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut Pasteur [Paris] (IP)-CHU Necker - Enfants Malades [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Sidra Medicine [Doha, Qatar], Université Paris Diderot - Paris 7 (UPD7)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Universitäts Klinikum Freiburg = University Medical Center Freiburg (Uniklinik), Sydney Children's hospital, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-CHU Necker - Enfants Malades [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), Howard Hughes Medical Institute [New York] (HHMI), Howard Hughes Medical Institute (HHMI)-New York University School of Medicine, Institut Pasteur [Paris]-CHU Necker - Enfants Malades [AP-HP], Beziat, Vivien, Li, Juan, Lin, Jian-Xin, Ma, Cindy S., Li, Peng, Bousfiha, Aziz, Pellier, Isabelle, Zoghi, Samaneh, Baris, Safa, Keles, Sevgi, Gray, Paul, Du, Ning, Wang, Yi, Zerbib, Yoann, Levy, Romain, Leclercq, Thibaut, About, Fredegonde, Lim, Ai Ing, Rao, Geetha, Payne, Kathryn, Pelham, Simon J., Avery, Danielle T., Deenick, Elissa K., Pillay, Bethany, Chou, Janet, Guery, Romain, Belkadi, Aziz, Guerin, Antoine, Migaud, Melanie, Rattina, Vimel, Ailal, Fatima, Benhsaien, Ibtihal, Bouaziz, Matthieu, Habib, Tanwir, Chaussabel, Damien, Marr, Nico, El-Benna, Jamel, Grimbacher, Bodo, Wargon, Orli, Bustamante, Jacinta, Boisson, Bertrand, Mueller-Fleckenstein, Ingrid, Fleckenstein, Bernhard, Chandesris, Marie-Olivia, Titeux, Matthias, Fraitag, Sylvie, Alyanakian, Marie-Alexandra, Leruez-Ville, Marianne, Picard, Capucine, Meyts, Isabelle, Di Santo, James P., Hovnanian, Alain, Somer, Ayper, Ozen, Ahmet, Rezaei, Nima, Chatila, Talal A., Abel, Laurent, Leonard, Warren J., Tangye, Stuart G., Puel, Anne, Casanova, Jean-Laurent

المصدر: Science Immunology
Science Immunology, American Association for the Advancement of Science, 2018, 3 (24), pp.eaat4956. ⟨10.1126/sciimmunol.aat4956⟩
Science Immunology, 2018, 3 (24), pp.eaat4956. ⟨10.1126/sciimmunol.aat4956⟩

مصطلحات موضوعية: 0301 basic medicine, INBORN-ERRORS, Immunoglobulin E, MESH: STAT3 Transcription Factor/immunology, Loss of heterozygosity, PRECISION MEDICINE, Transcription (biology), OF-FUNCTION MUTATIONS, STAT3, MESH: Transcription Factors/metabolism, CELL-DIFFERENTIATION, MESH: Th2 Cells/metabolism, MESH: Immunoglobulin E/immunology, MESH: Middle Aged, MESH: Gene Expression Regulation/immunology, Cell Differentiation, General Medicine, MESH: RNA, Messenger/metabolism, MESH: Immunoglobulin E/blood, MESH: Zinc Fingers/genetics, READ ALIGNMENT, MESH: Transcription, Genetic/immunology, MESH: Cell Nucleus/metabolism, MESH: Young Adult, [SDV.IMM]Life Sciences [q-bio]/Immunology, SIGNAL TRANSDUCER, Job Syndrome, MESH: Homozygote, STAT3 Transcription Factor, Cell type, MESH: Lymphocyte Count, MESH: Pedigree, MESH: STAT3 Transcription Factor/genetics, Immunology, Biology, Article, MESH: Job Syndrome/immunology, MESH: Genes, Recessive/genetics, DIFFERENTIAL EXPRESSION, MESH: Genes, Recessive/immunology, MESH: Job Syndrome/blood, MESH: Transcription Factors/genetics, 03 medical and health sciences, MESH: Whole Exome Sequencing, MESH: Exons/genetics, Humans, Transcription factor, Gene, MESH: Adolescent, MESH: Consanguinity, MESH: Humans, CLINICAL-FEATURES, MESH: Th17 Cells/metabolism, MESH: Th17 Cells/immunology, MESH: Cytokines/immunology, MESH: Adult, MESH: Loss of Function Mutation, MESH: Job Syndrome/genetics, MESH: Cell Differentiation/genetics, Molecular biology, MESH: Male, MESH: Th2 Cells/immunology, IL-21 RECEPTOR, 030104 developmental biology, Gene Expression Regulation, MESH: STAT3 Transcription Factor/metabolism, MESH: Promoter Regions, Genetic/genetics, MESH: Cell Differentiation/immunology, T-CELLS, STAT protein, biology.protein, Th17 Cells, MESH: Transcription Factors/immunology, MESH: Cytokines/metabolism, MESH: Female

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a014e03bf19bbdfb4eb205a53e190a3a
https://doi.org/10.1126/sciimmunol.aat4956

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Bystander immunotherapy as a strategy to control allergen-driven airway inflammation

المؤلفون: Sébastien Fleury, Severine Navarro, Nicolas Glaichenhaus, A Kanda, David Dombrowicz, Anne Lazzari, Valérie Julia

المساهمون: Immunologie des muqueuses et inflammation, Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Côte d'Azur (UCA), Institut de pharmacologie moléculaire et cellulaire (IPMC), Centre National de la Recherche Scientifique (CNRS)-Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Université Côte d'Azur (UCA), Récepteurs nucléaires, maladies cardiovasculaires et diabète - U 1011 (RNMCD), Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille)-Institut National de la Santé et de la Recherche Médicale (INSERM), This work was supported by a grant from the Fondation pour la Recherche Médicale and INSERM. S.N. was supported by a fellowship from the FRM, A.L. was supported by a fellowship from Vaincre la Mucoviscidose, and A.K is supported by a grant from the Agence Nationale de la Recherche (ANR)., We thank Nicolas Guy and the animal facility staff for their excellent animal care, as well as Julie Cazareth for the cell sorting experiments., Université Nice Sophia Antipolis (1965 - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Centre National de la Recherche Scientifique (CNRS)-Université Côte d'Azur (UCA), Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Derudas, Marie-Hélène

المصدر: Mucosal Immunology
Mucosal Immunology, Nature Pub. Group, 2015, 8 (4), pp.841-851. ⟨10.1038/mi.2014.115⟩
Mucosal Immunology, 2015, 8 (4), pp.841-851. ⟨10.1038/mi.2014.115⟩

مصطلحات موضوعية: immune tolerance, T reg, medicine.medical_treatment, Protozoan Proteins, MESH: Ovalbumin/administration & dosage, MESH: Asthma/immunology, airway inflammation, Lymphocyte Activation, medicine.disease_cause, Immunoglobulin E, T-Lymphocytes, Regulatory, Mice, Th2, 0302 clinical medicine, Allergen, MESH: Antigens, Protozoan/immunology, Immunology and Allergy, CTLA-4 Antigen, MESH: Animals, IL-2 receptor, Desensitization (medicine), MESH: Immunoglobulin E/immunology, MESH: Th2 Cells/metabolism, 0303 health sciences, MESH: T-Lymphocytes, Regulatory/immunology, biology, respiratory system, MESH: Ovalbumin/immunology, MESH: Respiratory Hypersensitivity/metabolism, MESH: CTLA-4 Antigen/metabolism, 3. Good health, MESH: T-Lymphocytes, Regulatory/metabolism, [SDV.IMM]Life Sciences [q-bio]/Immunology, Bronchoalveolar Lavage Fluid, specific immunotherapy, MESH: Respiratory Hypersensitivity/immunology, MESH: Desensitization, Immunologic*/methods, [SDV.IMM] Life Sciences [q-bio]/Immunology, Ovalbumin, MESH: Mice, Transgenic, Immunology, MESH: Asthma/metabolism, Antigens, Protozoan, Mice, Transgenic, Article, Inducible T-Cell Co-Stimulator Protein, 03 medical and health sciences, Th2 Cells, MESH: Inducible T-Cell Co-Stimulator Protein/metabolism, Antigen, In vivo, MESH: Allergens/administration & dosage, Respiratory Hypersensitivity, medicine, Animals, MESH: Mice, 030304 developmental biology, business.industry, MESH: Interleukin-2 Receptor alpha Subunit/metabolism, Interleukin-2 Receptor alpha Subunit, Immunotherapy, Allergens, asthma, MESH: Protozoan Proteins/immunology, MESH: Lymphocyte Activation/immunology, MESH: Th2 Cells/immunology, respiratory tract diseases, MESH: Respiratory Hypersensitivity/therapy, Disease Models, Animal, Desensitization, Immunologic, MESH: Bronchoalveolar Lavage Fluid/immunology, biology.protein, MESH: Allergens/immunology, MESH: Disease Models, Animal, business, MESH: Asthma/therapy, 030215 immunology

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1d213c53e8f68090bfc11e41706a54b
https://doi.org/10.1038/mi.2014.115

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5

MPLA shows attenuated pro-inflammatory properties and diminished capacity to activate mast cells in comparison with LPS

المؤلفون: Isabelle Angers, Stephen J. Galli, Adam Flaczyk, Salman T. Qureshi, Lothar Vogel, Ingo Spreitzer, Nicolas Gaudenzio, Sonja Wolfheimer, Stefan Schülke, B. Löschner, Mindy Tsai, Stephan Scheurer, Stefan Vieths

المساهمون: Paul-Ehrlich-Institute - Federal Institute for Vaccines and Biomedicines (EPI), Stanford University, McGill University Health Center [Montreal] (MUHC), German Research Foundation (DFG SCHU2951/1-1, SCHE637/3)

المصدر: Allergy
Allergy, Wiley, 2015, 70 (10), pp.1259-1268. ⟨10.1111/all.12675⟩

مصطلحات موضوعية: Lipopolysaccharides, Lipopolysaccharide, medicine.medical_treatment, Monophosphoryl Lipid A, MESH: Lipopolysaccharides / pharmacology, MESH: Mast Cells / metabolism, MESH: Monocytes / immunology, MESH: Dendritic Cells / drug effects, MESH: Mice, Knockout, Monocytes, MESH: Th2 Cells / immunology, chemistry.chemical_compound, Mice, Immunology and Allergy, MESH: Animals, Mast Cells, [SDV.IMM.ALL]Life Sciences [q-bio]/Immunology/Allergology, MESH: Dendritic Cells / metabolism, MESH: Lipid A / analogs & derivatives, Mice, Knockout, B-Lymphocytes, lipopolysaccharide, MESH: Mast Cells / drug effects, MESH: Inflammation Mediators / metabolism, Shock, Septic, MESH: Mast Cells / immunology, 3. Good health, MESH: B-Lymphocytes / immunology, MESH: B-Lymphocytes / metabolism, medicine.anatomical_structure, Lipid A, MESH: Epithelial Cells / metabolism, MESH: Adaptor Proteins, Vesicular Transport / genetics, MESH: Lipopolysaccharides / immunology, [SDV.IMM]Life Sciences [q-bio]/Immunology, Cytokines, MESH: Dendritic Cells / immunology, Inflammation Mediators, MESH: Shock, Septic / immunology, MESH: Antigens / immunology, Immunology, monophosphoryl lipid A, [SDV.BC]Life Sciences [q-bio]/Cellular Biology, Biology, MESH: Monocytes / drug effects, Immune system, Th2 Cells, adjuvant, MESH: Monocytes / metabolism, MESH: Adaptor Proteins, Vesicular Transport / metabolism, medicine, Animals, Humans, Secretion, MESH: Shock, Septic / metabolism, Antigens, MESH: Mice, MESH: Lipid A / immunology, MESH: Humans, MESH: Th2 Cells / metabolism, Monocyte, Epithelial Cells, Immunotherapy, Dendritic Cells, allergy, MESH: Lipid A / pharmacology, Adaptor Proteins, Vesicular Transport, Disease Models, Animal, chemistry, TLR4, MESH: Cytokines / biosynthesis, Cytokine secretion, MESH: Disease Models, Animal, MESH: Shock, Septic / genetics

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ead28381c905416c0cb2ec75c2a88011
https://pubmed.ncbi.nlm.nih.gov/26081583

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6

Role of Tyk-2 in Th9 and Th17 cells in allergic asthma

المؤلفون: Übel, Caroline, Graser, Anna, Koch, Sonja, Rieker, Ralf J., Lehr, Hans A., Müller, Mathias, Finotto, Susetta

المصدر: Scientific Reports
Scientific reports, vol. 4, pp. 5865

مصطلحات موضوعية: CD4-Positive T-Lymphocytes, Animals, Asthma/immunology, Asthma/metabolism, Asthma/pathology, CD4-Positive T-Lymphocytes/cytology, CD4-Positive T-Lymphocytes/immunology, Cell Differentiation, Cell Proliferation, Cytokines/metabolism, Disease Models, Animal, Interleukin-17/genetics, Interleukin-17/metabolism, Interleukin-17/pharmacology, Lung/metabolism, Mice, Mice, Inbred BALB C, Mice, Knockout, Ovalbumin/immunology, Phenotype, Recombinant Proteins/biosynthesis, Recombinant Proteins/genetics, Recombinant Proteins/pharmacology, Suppressor of Cytokine Signaling 3 Protein, Suppressor of Cytokine Signaling Proteins/metabolism, T-Lymphocytes, Helper-Inducer/drug effects, T-Lymphocytes, Helper-Inducer/immunology, T-Lymphocytes, Helper-Inducer/metabolism, TYK2 Kinase/genetics, TYK2 Kinase/metabolism, Th17 Cells/cytology, Th17 Cells/immunology, Th17 Cells/metabolism, Th2 Cells/cytology, Th2 Cells/immunology, Th2 Cells/metabolism, Ovalbumin, Suppressor of Cytokine Signaling Proteins, Article, Th2 Cells, Medizinische Fakultät, ddc:610, Lung, TYK2 Kinase, Interleukin-17, T-Lymphocytes, Helper-Inducer, Asthma, Recombinant Proteins, Cytokines, Th17 Cells

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::449d9a72dc831f2aea32846f2e8118b9
https://pubmed.ncbi.nlm.nih.gov/25109392

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7

Cytokine production by T-cell clones from bronchoalveolar lavage fluid of patients with asthma and healthy subjects

المصدر: European respiratory journal. Supplement. 22:95s-103s

مصطلحات موضوعية: Adult, Interleukin-2/biosynthesis, Bronchoalveolar Lavage Fluid/cytology, Interleukin-4/biosynthesis, Asthma/blood, Th2 Cells/metabolism, CD2 Antigens/immunology, Blocking/immunology, Lymphocyte Activation, Tetradecanoylphorbol Acetate/immunology, Antibodies, Clone Cells/metabolism, Interferon-gamma/biosynthesis, CD4-Positive T-Lymphocytes/immunology, Humans, CD28 Antigens/immunology, CD3 Complex/pharmacology, Th1 Cells/metabolism

URL الوصول: https://explore.openaire.eu/search/publication?articleId=dris___00893::0b3c3aeea21059f91e46e4bbd169882f

8

OatA, a Peptidoglycan O-Acetyltransferase Involved in Listeria monocytogenes Immune Escape, Is Critical for Virulence

المؤلفون: Martin Sachse, Pascale Cossart, Olivier Dussurget, Jérémie Decalf, Céline Goulard, Ivo G. Boneca, Camille Aubry, Marie-Anne Nahori, Nadège Cayet

المساهمون: Interactions Bactéries-Cellules (UIBC), Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut Pasteur [Paris]-Institut National de la Recherche Agronomique (INRA), Microscopie ultrastructurale (plate-forme), Institut Pasteur [Paris], Immunobiologie des Cellules Dendritiques, Institut Pasteur [Paris]-Institut National de la Santé et de la Recherche Médicale (INSERM), Groupe Avenir, Institut National de la Santé et de la Recherche Médicale (INSERM), Biologie et Génétique de la Paroi bactérienne - Biology and Genetics of Bacterial Cell Wall (BGPB), Université Paris Diderot - Paris 7 (UPD7), This work was supported by Institut Pasteur, Institut National de la Santé et de la Recherche Médicale, Institut National de la Recherche Agronomique, European Research Council (Advanced grant 233348 to P. C. and Starting grant 202283 to I. G. B.), Fondation Pasteur-Weizmann, Fondation Jeantet, and Fondation le Roch Les Mousquetaires. P. C. is an international research scholar of the Howard Hughes Medical Institute. C. A. is a doctoral fellow of the Ministère de l’Enseignement Supérieur et de la Recherche., Institut National de la Recherche Agronomique (INRA)-Institut Pasteur [Paris]-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut National de la Recherche Agronomique (INRA)-Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut Pasteur [Paris] (IP), Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM)

المصدر: Journal of Infectious Diseases
Journal of Infectious Diseases, Oxford University Press (OUP), 2011, 204 (5), pp.731-40. ⟨10.1093/infdis/jir396⟩
Journal of Infectious Diseases, 2011, 204 (5), pp.731-40. ⟨10.1093/infdis/jir396⟩

مصطلحات موضوعية: INTERLEUKIN-6-DEFICIENT MICE, MESH: Liver/microbiology, MESH: Spleen/microbiology, Mutant, MESH: Acetyltransferases/genetics, medicine.disease_cause, MESH: Acetyltransferases/immunology, chemistry.chemical_compound, Mice, INFECTION, Immunology and Allergy, Listeriosis, MESH: Animals, MESH: Virulence Factors/immunology, NEUTROPHILS, TUMOR-NECROSIS-FACTOR, 0303 health sciences, Mice, Inbred BALB C, MESH: Microbial Sensitivity Tests, MESH: Th2 Cells/metabolism, IFN-GAMMA, biology, MESH: Macrophages/immunology, Acetylation, MESH: Listeriosis/immunology, 3. Good health, Infectious Diseases, Liver, MESH: Listeria monocytogenes/genetics, Muramic Acids, Cytokines, [SDV.IMM]Life Sciences [q-bio]/Immunology, Female, MESH: Immunity, Innate, MESH: Acetylation, INTERFERON, Virulence Factors, MESH: Mice, Inbred BALB C, Virulence, Microbial Sensitivity Tests, Peptidoglycan, Microbiology, Cell Line, Lethal Dose 50, 03 medical and health sciences, Major Articles and Brief Reports, Immune system, DEFICIENT, Th2 Cells, Listeria monocytogenes, Acetyltransferases, MESH: Liver/metabolism, MESH: Listeriosis/genetics, medicine, MESH: Virulence Factors/genetics, Animals, Humans, Secretion, MESH: Macrophages/metabolism, MESH: Mice, MESH: Muramic Acids/metabolism, 030304 developmental biology, STAPHYLOCOCCUS-AUREUS, Innate immune system, MESH: Humans, MESH: Peptidoglycan/immunology, 030306 microbiology, MESH: Listeria monocytogenes/growth & development, Macrophages, MESH: Listeria monocytogenes/pathogenicity, Th1 Cells, biology.organism_classification, Immunity, Innate, MESH: Cell Line, MESH: Listeria monocytogenes/immunology, MESH: Lethal Dose 50, chemistry, MESH: Th1 Cells/metabolism, Listeria, MESH: Cytokines/metabolism, MESH: Peptidoglycan/chemistry, MESH: Female, RESISTANCE, Spleen, RESPONSES