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المؤلفون: Sreenath V. Sharma, Junichi Kurebayashi, Shiro Akinaga, Yoji Ikuina, Leonard M. Neckers, Tatsuya Tamaoki, Yukimasa Shiotsu, Chikara Murakata, Harunobu Tahara, Theodor W. Schulte, Shiro Soga, Makiko Shimizu, Kazuo Yamaguchi
المصدر: Cancer Chemotherapy and Pharmacology. 48:435-445
مصطلحات موضوعية: Cancer Research, Mice, Nude, Apoptosis, Breast Neoplasms, Toxicology, Lactones, Mice, Structure-Activity Relationship, chemistry.chemical_compound, In vivo, Oximes, Tumor Cells, Cultured, polycyclic compounds, Animals, Humans, Pharmacology (medical), HSP90 Heat-Shock Proteins, Enzyme Inhibitors, Pharmacology, Mice, Inbred BALB C, biology, Ansamycin, Stereoisomerism, Biological activity, Genes, erbB-2, Geldanamycin, Hsp90, In vitro, Radicicol, Gene Expression Regulation, Oncology, chemistry, Biochemistry, Herbimycin, Injections, Intravenous, biology.protein, Cancer research, Female, Macrolides
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2
المؤلفون: Mikhail V. Blagosklonny, Benjamin Knepper, Jane B. Trepel, J. Frederic Mushinski, Olaf Schaefer, Farzaneh Pirnia, Maria Tsokos, Jung Sik Kim, Yung Hyun Choi, Michael J. Birrer, Phuong Mai Nguyen, Theodor W. Schulte
المصدر: Oncogene. 19:6082-6090
مصطلحات موضوعية: Cyclin-Dependent Kinase Inhibitor p21, Cancer Research, Cell cycle checkpoint, Tumor suppressor gene, Cellular differentiation, Down-Regulation, Apoptosis, Cell Cycle Proteins, Sarcoma, Ewing, Biology, Retinoblastoma Protein, Cyclins, Ectoderm, Mitotic Index, Tumor Cells, Cultured, Genetics, medicine, Humans, Lovastatin, Progenitor cell, Molecular Biology, Cell Size, Neurons, Tumor Suppressor Proteins, G1 Phase, Retinoblastoma protein, DNA, Cell cycle, Flow Cytometry, medicine.disease, Immunohistochemistry, Genes, cdc, Primitive neuroectodermal tumor, Microscopy, Electron, Scanning, Cancer research, biology.protein, Microtubule-Associated Proteins, Biomarkers, Cyclin-Dependent Kinase Inhibitor p27, medicine.drug
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3
المؤلفون: Edward G. Mimnaugh, Theodor W. Schulte, Len Neckers
المصدر: Drug Resistance Updates. 2:165-172
مصطلحات موضوعية: Pharmacology, Cancer Research, Cell signaling, GTPase-activating protein, Kinase, Biology, Hsp90, Cell biology, Infectious Diseases, Oncology, Chaperone (protein), Heat shock protein, Cancer cell, biology.protein, Pharmacology (medical), Tyrosine
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4
المصدر: Molecular Genetics and Metabolism. 66:24-30
مصطلحات موضوعية: Proteasome Endopeptidase Complex, Lactams, Macrocyclic, Endocrinology, Diabetes and Metabolism, PTK2, Biology, Biochemistry, Focal adhesion, Mice, chemistry.chemical_compound, Endocrinology, Multienzyme Complexes, Enzyme Stability, Benzoquinones, Tumor Cells, Cultured, Genetics, Animals, RNA, Messenger, Enzyme Inhibitors, Molecular Biology, PTK2B, Hydrolysis, Ansamycin, Quinones, 3T3 Cells, Protein-Tyrosine Kinases, Geldanamycin, Hsp90, Cysteine Endopeptidases, Rifabutin, chemistry, Focal Adhesion Kinase 1, Focal Adhesion Protein-Tyrosine Kinases, Cancer research, biology.protein, biological phenomena, cell phenomena, and immunity, Signal transduction, Cell Adhesion Molecules, Tyrosine kinase
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المؤلفون: Leonard M. Neckers, Theodor W. Schulte
المصدر: Cancer Chemotherapy and Pharmacology. 42:273-279
مصطلحات موضوعية: Cancer Research, Receptor, ErbB-2, Lactams, Macrocyclic, Tanespimycin, Toxicology, Receptor tyrosine kinase, Mice, chemistry.chemical_compound, Benzoquinones, Tumor Cells, Cultured, Animals, Humans, Pharmacology (medical), MTT assay, HSP90 Heat-Shock Proteins, Enzyme Inhibitors, Pharmacology, Antibiotics, Antineoplastic, biology, Ansamycin, Quinones, 3T3 Cells, Protein-Tyrosine Kinases, Geldanamycin, Hsp90, Benzoquinone, Proto-Oncogene Proteins c-raf, Rifabutin, Oncology, chemistry, Biochemistry, Mutation, Cancer research, biology.protein, Female, Tumor Suppressor Protein p53, Tyrosine kinase, Cell Division
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6
المؤلفون: Leonard M. Neckers, Won G. An, Theodor W. Schulte
المصدر: Biochemical and Biophysical Research Communications. 239:655-659
مصطلحات موضوعية: Proteasome Endopeptidase Complex, Proteases, Lactams, Macrocyclic, Biophysics, Cysteine Proteinase Inhibitors, Biology, Biochemistry, Mice, chemistry.chemical_compound, Ubiquitin, Multienzyme Complexes, Heat shock protein, Enzyme Stability, Benzoquinones, Animals, Molecular Biology, Transcription factor, Quinones, 3T3 Cells, Cell Biology, Geldanamycin, Hsp90, Cell biology, Proto-Oncogene Proteins c-raf, Cysteine Endopeptidases, Proteasome, chemistry, Calcium-Calmodulin-Dependent Protein Kinases, biology.protein, Signal transduction
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7
المؤلفون: Leonard M. Neckers, Jenny Clark, Theodor W. Schulte, David O. Toft, William P. Sullivan, Hans Joachim Ochel, Timothy A.J. Haystead, Patrick Fadden, James P. Grenert, Edward A. Sausville, Henry C. Krutzsch, Edward G. Mimnaugh
المصدر: Journal of Biological Chemistry. 272:23843-23850
مصطلحات موضوعية: Protein Conformation, Lactams, Macrocyclic, Molecular Sequence Data, Plasma protein binding, Biochemistry, chemistry.chemical_compound, Adenosine Triphosphate, Protein structure, Heat shock protein, Benzoquinones, polycyclic compounds, Humans, Amino Acid Sequence, HSP90 Heat-Shock Proteins, Molecular Biology, Sequence Deletion, biology, Chemistry, Quinones, Cell Biology, Geldanamycin, Hsp90, Adenosine Diphosphate, Mutagenesis, Chaperone (protein), biology.protein, Biophysics, ATP–ADP translocase, Protein Binding, Binding domain
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d55e2446bd75c5ed1248435178c5f9b5
https://doi.org/10.1074/jbc.272.38.23843 -
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المؤلفون: Elisabeth Ress, Leonard M. Neckers, Theodor W. Schulte, Jeffrey A. Toretsky, Lee J. Helman
المصدر: Biochemical and Molecular Medicine. 60:121-126
مصطلحات موضوعية: PAX3, Gene Expression, Chromosomal translocation, Sarcoma, Ewing, Biology, Polymerase Chain Reaction, Biochemistry, Mice, Biomarkers, Tumor, Tumor Cells, Cultured, medicine, Animals, Humans, Paired Box Transcription Factors, Child, PAX3 Transcription Factor, Gene, Base Sequence, Ewing's sarcoma, Neural crest, medicine.disease, DNA-Binding Proteins, Cell culture, embryonic structures, Immunology, Cancer research, Alveolar rhabdomyosarcoma, Sarcoma, Oligonucleotide Probes, Transcription Factors
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المؤلفون: Yukimasa Shiotsu, Ivo Wortman, Theodor W. Schulte, Shiro Soga, Leonard M. Neckers, Chikara Murakata, Tatsuya Tamaoki, Shiro Akinaga, Won G. An
المصدر: Blood. 96(6)
مصطلحات موضوعية: Antifungal Agents, Erythroblasts, Cellular differentiation, Lactams, Macrocyclic, Immunology, Fusion Proteins, bcr-abl, Philadelphia chromosome, Biochemistry, chemistry.chemical_compound, Lactones, Mice, hemic and lymphatic diseases, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, medicine, Benzoquinones, Animals, Humans, HSP90 Heat-Shock Proteins, Antibiotics, Antineoplastic, biology, G1 Phase, Quinones, Cell Differentiation, Cell Biology, Hematology, medicine.disease, Hsp90, Molecular biology, Fusion protein, Radicicol, chemistry, Rifabutin, Cancer research, biology.protein, Macrolides, K562 Cells, Tyrosine kinase, K562 cells, Chronic myelogenous leukemia
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19ef5dc83dcda58fcf8ebfc810e0fdc5
https://pubmed.ncbi.nlm.nih.gov/10979978