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1
المؤلفون: Donnicia James, Anish Kurian, Chintan Patel, Lori-Ann Christie, Thomas C. Hohman, Wenzheng Hu, Matthew S Lawrence, Richard Torres, Robin J Goody
المصدر: Exp Eye Res
مصطلحات موضوعية: 0301 basic medicine, Retinal degeneration, Male, medicine.medical_specialty, genetic structures, Fundus Oculi, Retinal Neovascularization, Article, Neovascularization, 03 medical and health sciences, Cellular and Molecular Neuroscience, chemistry.chemical_compound, 0302 clinical medicine, Ophthalmology, Chlorocebus aethiops, medicine, Animals, Fluorescein Angiography, Macular telangiectasia, Aflibercept, medicine.diagnostic_test, business.industry, Vascular disease, Retinal Vessels, Retinal, Diabetic retinopathy, medicine.disease, Fluorescein angiography, Sensory Systems, eye diseases, Disease Models, Animal, 030104 developmental biology, chemistry, Chronic Disease, 030221 ophthalmology & optometry, Female, sense organs, medicine.symptom, business, Tomography, Optical Coherence, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a490ff26080236809ae0de0a348599af
https://europepmc.org/articles/PMC7335215/ -
2
المؤلفون: Gerard A. Rodrigues, Candice Hansen, Lisa M. Hernández, Keith A. Luhrs, Matthew Mason, James R. Burke, Thomas C. Hohman, Lori-Ann Christie
المصدر: Investigative Opthalmology & Visual Science. 59:5836
مصطلحات موضوعية: Vascular Endothelial Growth Factor A, 0301 basic medicine, genetic structures, Angiogenesis, Recombinant Fusion Proteins, Angiogenesis Inhibitors, Vascular permeability, Retinal Neovascularization, Pharmacology, Capillary Permeability, Neovascularization, Mice, 03 medical and health sciences, 0302 clinical medicine, In vivo, Ranibizumab, Human Umbilical Vein Endothelial Cells, medicine, Animals, Humans, Corneal Neovascularization, Tube formation, Chemistry, Nuclear Proteins, General Medicine, medicine.disease, eye diseases, Bevacizumab, Disease Models, Animal, Vascular endothelial growth factor A, 030104 developmental biology, DARPin, Corneal neovascularization, 030221 ophthalmology & optometry, Blood Vessels, Calcium, Rabbits, medicine.symptom
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a3ce73e8c1d47b7cf27d22af5e1befb
https://doi.org/10.1167/iovs.18-25307 -
3
المؤلفون: Thomas C. Hohman
المصدر: Handbook of Experimental Pharmacology ISBN: 9783319582887
مصطلحات موضوعية: 0301 basic medicine, Retinal degeneration, Genetics, Leber's hereditary optic neuropathy, Biology, Gene mutation, medicine.disease, eye diseases, Choroideremia, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, RPE65, Retinitis pigmentosa, 030221 ophthalmology & optometry, medicine, Leber's congenital amaurosis, Retinal Dystrophies
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::51d25007ee96b9e6a3d9ddc1dbaedc67
https://doi.org/10.1007/164_2016_91 -
4
المؤلفون: Thomas C. Hohman, Ryuichi Wada, Shin-Ichiro Yamagishi, Masayuki Baba, Soroku Yagihashi, Yasuo Kokai, Chihiro Yabe-Nishimura
المصدر: Brain. 124:2448-2458
مصطلحات موضوعية: medicine.medical_specialty, Diabetic neuropathy, Neural Conduction, Enzyme-Linked Immunosorbent Assay, Mice, Transgenic, Biology, Diabetes Mellitus, Experimental, Mice, Polyol pathway, Diabetic Neuropathies, Aldehyde Reductase, Internal medicine, Diabetes mellitus, medicine, Animals, Humans, Enzyme Inhibitors, Protein Kinase C, Motor Neurons, Aldose reductase, medicine.disease, Streptozotocin, Sciatic Nerve, Aldose reductase inhibitor, Mice, Inbred C57BL, Glucose, Endocrinology, Peripheral neuropathy, Mice, Inbred DBA, Hyperglycemia, Female, Neurology (clinical), Sciatic nerve, Sodium-Potassium-Exchanging ATPase, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fd2efb43a528da6e5cd69c6029a224d
https://doi.org/10.1093/brain/124.12.2448 -
5
المؤلفون: W. Gerald Robison, J. L. Jacot, Michael D. Basso, J P Glover, Thomas C. Hohman
المصدر: Journal of Ocular Pharmacology and Therapeutics. 16:167-172
مصطلحات موضوعية: medicine.medical_specialty, H&E stain, Weanling, Basement Membrane, Diabetes Mellitus, Experimental, Rats, Sprague-Dawley, chemistry.chemical_compound, Aldehyde Reductase, Ophthalmology, medicine, Animals, Pharmacology (medical), Enzyme Inhibitors, Pharmacology, Diabetic Retinopathy, Chemistry, Elastase, Galactose, Retinal Vessels, Retinal, Anatomy, medicine.disease, Capillaries, Rats, medicine.anatomical_structure, Capillary length, Female, Dilatation, Pathologic, Retinopathy, Optic disc
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3fbdd6f52a8c1f30fc1813b738f5692
https://doi.org/10.1089/jop.2000.16.167 -
6
المؤلفون: Suresh B. Singh, Michael S. Malamas, Thomas C. Hohman, Deborah Carper, Ramaswamy Nilakantan, Douglas B. Kitchen
المصدر: Journal of Medicinal Chemistry. 43:1062-1070
مصطلحات موضوعية: Models, Molecular, Stereochemistry, Crystallography, X-Ray, Cofactor, Structure-Activity Relationship, Aldehyde Reductase, Drug Discovery, medicine, Humans, Benzothiazoles, Enzyme Inhibitors, Binding site, chemistry.chemical_classification, Aldose reductase, Binding Sites, biology, Chemistry, Active site, Aldose reductase inhibitor, Recombinant Proteins, Thiazoles, Enzyme, Biochemistry, Enzyme inhibitor, Mutagenesis, Site-Directed, biology.protein, Phthalazines, Molecular Medicine, medicine.drug
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7
المؤلفون: Thomas C. Hohman
المصدر: Retina. 29:S51-S53
مصطلحات موضوعية: Vascular Endothelial Growth Factor A, Oncology, medicine.medical_specialty, genetic structures, Combination therapy, medicine.medical_treatment, Angiogenesis Inhibitors, Disease, Antibodies, Monoclonal, Humanized, Macular Degeneration, chemistry.chemical_compound, Ranibizumab, Internal medicine, medicine, Animals, Humans, business.industry, Antibodies, Monoclonal, Retinal, General Medicine, Macular degeneration, medicine.disease, Choroidal Neovascularization, Vascular endothelial growth factor, Ophthalmology, Choroidal neovascularization, Cytokine, chemistry, Drug Design, Drug Therapy, Combination, medicine.symptom, business, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55f2a4ea02ad658b4026c5dc835ab0a4
https://doi.org/10.1097/iae.0b013e3181ad23b5 -
8
المصدر: Diabetologia. 42:1120-1130
مصطلحات موضوعية: Male, medicine.medical_specialty, Diabetic neuropathy, Endocrinology, Diabetes and Metabolism, Neural Conduction, Nerve conduction velocity, Diabetes Mellitus, Experimental, Rats, Sprague-Dawley, chemistry.chemical_compound, Alkaloids, Diabetic Neuropathies, Piperidines, Internal medicine, Diabetes mellitus, Internal Medicine, medicine, Animals, Enzyme Inhibitors, Protein Kinase C, Protein kinase C, Benzophenanthridines, Chemistry, Glutathione, Streptozotocin, medicine.disease, Sciatic Nerve, Phenanthridines, Rats, Endocrinology, Chelerythrine, Regional Blood Flow, Sciatic nerve, Sodium-Potassium-Exchanging ATPase, medicine.drug
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9
المؤلفون: Michelle H. McGowan, Tatiana Putilina, Ossama El-Kabbani, Kehdih Lai, Thomas C. Hohman, Michael S. Malamas, Deborah Carper, Yi-Qun Wane
المصدر: European Journal of Biochemistry. 256:310-316
مصطلحات موضوعية: Models, Molecular, Tolrestat, Stereochemistry, Naphthalenes, Imidazolidines, Biochemistry, chemistry.chemical_compound, Aldehyde Reductase, Humans, Computer Simulation, Benzothiazoles, Enzyme Inhibitors, Binding site, Site-directed mutagenesis, Alanine, chemistry.chemical_classification, Aldose reductase, Binding Sites, Molecular Structure, biology, Imidazoles, Active site, Recombinant Proteins, Kinetics, Thiazoles, Enzyme, chemistry, Mutagenesis, Site-Directed, biology.protein, Phthalazines, Sorbinil, NADP
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10
المؤلفون: T. Coste, Norman E Cameron, Philippe Vague, Dominique Dufayet, Thomas C. Hohman, Denis Raccah
المصدر: Journal of Diabetes and its Complications. 12:154-162
مصطلحات موضوعية: Blood Glucose, Male, medicine.medical_specialty, Tolrestat, Erythrocytes, Kidney Cortex, Diabetic neuropathy, Endocrinology, Diabetes and Metabolism, Neural Conduction, Naphthalenes, Kidney, Nerve conduction velocity, Diabetes Mellitus, Experimental, Rats, Sprague-Dawley, chemistry.chemical_compound, Sugar Alcohols, Endocrinology, Polyol pathway, Aldehyde Reductase, Internal medicine, Internal Medicine, medicine, Animals, Hypoglycemic Agents, Kidney Medulla, Aldose reductase, business.industry, Body Weight, Sodium, Kidney metabolism, medicine.disease, Sciatic Nerve, Aldose reductase inhibitor, Rats, chemistry, Sciatic nerve, Sodium-Potassium-Exchanging ATPase, business, Inositol, medicine.drug