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المؤلفون: Mark A. Ashwell, Jean-Marc Lapierre, Christopher Brassard, Karen Bresciano, Cathy Bull, Susan Cornell-Kennon, Sudharshan Eathiraj, Dennis S. France, Terence Hall, Jason Hill, Eoin Kelleher, Sampada Khanapurkar, Darin Kizer, Steffi Koerner, Jeff Link, Yanbin Liu, Sapna Makhija, Magdi Moussa, Nivedita Namdev, Khanh Nguyen, Robert Nicewonger, Rocio Palma, Jeff Szwaya, Manish Tandon, Uma Uppalapati, David Vensel, Laurie P. Volak, Erika Volckova, Neil Westlund, Hui Wu, Rui-Yang Yang, Thomas C. K. Chan
المصدر: Journal of Medicinal Chemistry. 55:5291-5310
مصطلحات موضوعية: Models, Molecular, Protein Conformation, Pyridines, Administration, Oral, Biological Availability, AKT1, Antineoplastic Agents, Plasma protein binding, Pharmacology, Crystallography, X-Ray, Mice, Structure-Activity Relationship, Adenosine Triphosphate, In vivo, Catalytic Domain, Cell Line, Tumor, Drug Discovery, Animals, Humans, Structure–activity relationship, Phosphorylation, Protein kinase B, Adaptor Proteins, Signal Transducing, Cell Proliferation, Effector, Chemistry, Imidazoles, Ribosomal Protein S6 Kinases, 70-kDa, Small molecule, Biochemistry, Microsomes, Liver, Molecular Medicine, Proto-Oncogene Proteins c-akt, Protein Binding
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المصدر: NeuroReport. 9:1441-1445
مصطلحات موضوعية: Male, medicine.medical_specialty, Time Factors, Microinjections, Bone Morphogenetic Protein 7, Hindlimb, Motor Activity, Cisterna magna, Bone morphogenetic protein, Rats, Sprague-Dawley, Central nervous system disease, Transforming Growth Factor beta, Internal medicine, medicine.artery, Cisterna Magna, Forelimb, medicine, Animals, Humans, Stroke, Analysis of Variance, Cerebral infarction, business.industry, General Neuroscience, Body Weight, Brain, Cerebral Infarction, Anatomy, medicine.disease, Recombinant Proteins, Rats, Endocrinology, medicine.anatomical_structure, Ischemic Attack, Transient, Bone Morphogenetic Proteins, Middle cerebral artery, business
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f34117bd5a68a8e24048d213b587d019
https://doi.org/10.1097/00001756-199805110-00035 -
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المؤلفون: Sudharshan, Eathiraj, Rocio, Palma, Marscha, Hirschi, Erika, Volckova, Enkeleda, Nakuci, Jennifer, Castro, Chang-Rung, Chen, Thomas C K, Chan, Dennis S, France, Mark A, Ashwell
المصدر: The Journal of biological chemistry. 286(23)
مصطلحات موضوعية: Models, Molecular, Adenosine Triphosphate, Amino Acid Motifs, Drug Discovery, Protein Structure and Folding, Humans, Receptor, Fibroblast Growth Factor, Type 1, Receptor, Fibroblast Growth Factor, Type 2, Crystallography, X-Ray, Hydrophobic and Hydrophilic Interactions, Protein Kinase Inhibitors
URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::f4080ba3e8ecb351624ad074f72bb215
https://pubmed.ncbi.nlm.nih.gov/21454610 -
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المؤلفون: Thomas C. K. Chan, Raymond L. Konger
المصدر: Journal of Cellular Physiology. 156:515-521
مصطلحات موضوعية: medicine.medical_specialty, Physiology, Clinical Biochemistry, Biology, chemistry.chemical_compound, Epidermal growth factor, Internal medicine, Tumor Cells, Cultured, medicine, Humans, Growth medium, Binding Sites, Transglutaminases, Epidermal Growth Factor, Cell growth, Cell Differentiation, Cell Biology, In vitro, Cell biology, Endocrinology, chemistry, Epidermoid carcinoma, Cell culture, Carcinoma, Squamous Cell, Growth inhibition, A431 cells, hormones, hormone substitutes, and hormone antagonists
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المؤلفون: Chang-Rung Chen, Jean-Marc Lapierre, Jeffrey D. Szwaya, Yanbin Liu, Nivedita Namdev, Deirdre Lowe, Ron E. Savage, Cathy O. Bull, Thomas C K Chan, Mark A. Ashwell, Dennis S. France
المصدر: Cancer Research. 70:4501-4501
مصطلحات موضوعية: MAPK/ERK pathway, Cancer Research, Kinase, business.industry, Kinase insert domain receptor, Germline mutation, Oncology, In vivo, Cancer cell, Immunology, Cancer research, Medicine, business, Cytotoxicity, V600E
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::307f78968438b6539349eba914aca660
https://doi.org/10.1158/1538-7445.am10-4501 -
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المؤلفون: Stephen B. Howell, Thomas C. K. Chan, Stephen Cleary, Maurie Markman
المصدر: Cancer chemotherapy and pharmacology. 19(1)
مصطلحات موضوعية: Adult, Male, Phosphonoacetic Acid, Cancer Research, Combination therapy, Gastrointestinal Diseases, medicine.medical_treatment, Pharmacology, Toxicology, chemistry.chemical_compound, Organophosphorus Compounds, Oral administration, Neoplasms, Antineoplastic Combined Chemotherapy Protocols, Medicine, Humans, Pharmacology (medical), Uridine, Aged, Aged, 80 and over, Chemotherapy, Aspartic Acid, business.industry, Headache, Drug Synergism, Dipyridamole, Middle Aged, Clinical trial, Oncology, chemistry, Toxicity, Drug Evaluation, Female, business, Nucleoside, medicine.drug
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المؤلفون: Craig E. Pfeifle, Raymond Taetle, Thomas C. K. Chan, Ian Abramson, Maurie Markman, Stephen B. Howell
المصدر: Cancer Chemotherapy and Pharmacology. 22
مصطلحات موضوعية: Adult, Male, Cancer Research, medicine.medical_specialty, Biological Availability, Pilot Projects, Toxicology, chemistry.chemical_compound, Pharmacokinetics, Bone Marrow, Neoplasms, Internal medicine, Blood plasma, medicine, Humans, Pharmacology (medical), Uridine, Acivicin, Pharmacology, Volume of distribution, Metabolism, Middle Aged, medicine.anatomical_structure, Endocrinology, Oncology, chemistry, Female, Bone marrow, Nucleoside, Half-Life
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