المؤلفون: Hernandez, J. Andres, Nagy Atia, Andrew, Thomas Hollenbeck, Scott

المصدر: In Plastic Surgery Edition: Fifth Edition. 2024:311-326

المؤلفون: John Isbell, Ashley Chong, Patrick White, Thomas Hollenbeck, Lucas Westling, Stefan J. Thibodeaux

المصدر: Journal of pharmaceutical sciences. 109(11)

مصطلحات موضوعية: Electrospray, Pharmaceutical Science, 02 engineering and technology, Mass spectrometry, 030226 pharmacology & pharmacy, 03 medical and health sciences, Mice, 0302 clinical medicine, Dogs, Tandem Mass Spectrometry, Drug Discovery, Animals, Acoustic droplet ejection, Liver microsomes, ADME, Chromatography, Chemistry, Acoustics, Metabolic stability, 021001 nanoscience & nanotechnology, Ion source, Rats, Microsomes, Liver, 0210 nano-technology, Drug metabolism, Chromatography, Liquid

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5936fda21cfd78333fc751c65f27f051
https://pubmed.ncbi.nlm.nih.gov/32745563

المؤلفون: W. Perry Gordon, Tove Tuntland, Shelly Meeusen, Leah Clemmer, Sara Da Ros, Laura Bordone, Robert Hill, Thomas Hollenbeck, John W. Fathman, Kenneth Ng, Sheryll Espinola, Xiaohui He, Bo Liu, John Nelson, Maya Iskandar, Xue-Feng Zhu, Vân Nguyen-Tran, Andreas Kreusch, David C.S. Huang, Songchun Jiang, Yong Jia, Badry Bursulaya, Janine E. Baaten, Jian Shi, Mu-Yun Gao, Tao Jiang, Barun Okram, Glen Spraggon, Pierre-Yves Michellys, Hong Liu

المصدر: ACS Medicinal Chemistry Letters. 8:1048-1053

مصطلحات موضوعية: 0301 basic medicine, Kinase, Organic Chemistry, Pattern recognition receptor, Biology, Biochemistry, digestive system diseases, RIPK2, Serine, 03 medical and health sciences, 030104 developmental biology, In vivo, NOD2, Drug Discovery, Tyrosine kinase, Ex vivo

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c03b4d7782a1105eb048003151bbcc2
https://doi.org/10.1021/acsmedchemlett.7b00258

المؤلفون: Chek Shik Lim, Advait Nagle, Chun Li, Clemens H. M. Kocken, Pranab Mishra, Tove Tuntland, Wei Lin Sandra Sim, Rachel Borboa, Case W. McNamara, Seh Yong Leong, Nobutaka Kato, Christophe Bodenreider, Anne-Marie Zeeman, Prasuna Guntapalli, Kelli Kuhen, Thomas Hollenbeck, Thierry T. Diagana, Arnab K. Chatterjee, Elizabeth A. Winzeler, Liying Jocelyn Tan, Jonathan Chang, Siti Nurdiana Abas, Paul W. Smith, Bryan K. S. Yeung, Yong Cheng Tan, David C. Tully, Jason Roland, Suresh B. Lakshminarayana, Bin Zou, Kerstin Gagaring

المصدر: ACS Medicinal Chemistry Letters. 5:947-950

مصطلحات موضوعية: 0303 health sciences, Imidazopyridine, 030306 microbiology, Phenotypic screening, Organic Chemistry, Cell, Biology, Simian, Bioinformatics, biology.organism_classification, Biochemistry, Virology, Plasmodium, 3. Good health, 03 medical and health sciences, medicine.anatomical_structure, In vivo, parasitic diseases, Drug Discovery, medicine, Structure–activity relationship, Parasite hosting, 030304 developmental biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d417d8d40c2968e0a864417b3499fd6
https://doi.org/10.1021/ml500244m

المؤلفون: Xuena Lin, Kelli Kuhen, Tao Wu, Elizabeth A. Winzeler, Christoph Fischli, Chun Li, Kerstin Gagaring, Jared Ek, Tiffany Chuan, Suresh B. Lakshminarayana, Rachel Borboa, Thomas Hollenbeck, Arnab K. Chatterjee, Fenghua Liu, Thierry T. Diagana, Richard Glynne, Caroline Francek, Reto Brun, Advait Nagle, John Isbell, Bo Liu, Christopher Caldwell, David C. Tully, David Plouffe, Tove Tuntland, Philip B. Alper, Suzanne Skolnik, Jonathan Chang, Jianling Wang, Matthias Rottmann, Zhong Chen

المصدر: Journal of Medicinal Chemistry

مصطلحات موضوعية: Plasmodium falciparum, Biological Availability, Pharmacology, Article, Piperazines, Antimalarials, Mice, Structure-Activity Relationship, chemistry.chemical_compound, Pharmacokinetics, In vivo, Drug Discovery, Animals, Humans, Structure–activity relationship, Potency, Antimalarial Agent, Malaria, Falciparum, Rats, Wistar, Mice, Inbred BALB C, biology, Imidazoles, biology.organism_classification, In vitro, Rats, Piperazine, chemistry, Molecular Medicine, Caco-2 Cells

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f67dd0822748c0b26acd0f3ad90e7ef8
https://doi.org/10.1021/jm300041e

المؤلفون: Thomas Hollenbeck, Christine Tumanut, Donald S. Karanewsky, Robert Epple, Michael J. Roberts, Hong Liu, Michael Hornsby, Glen Spraggon, David H. Woodmansee, Brian T. Masick, Tove Tuntland, Jonathan Chang, David C. Tully, Jun Li, Jennifer A. Williams, Jennifer L. Harris, Phil B. Alper, Perry Gordon, Arnab K. Chatterjee

المصدر: Bioorganic & Medicinal Chemistry Letters. 16:5112-5117

مصطلحات موضوعية: Male, Stereochemistry, Peptidomimetic, Clinical Biochemistry, Administration, Oral, Biological Availability, Pharmaceutical Science, Crystallography, X-Ray, Biochemistry, Chemical synthesis, Structure-Activity Relationship, chemistry.chemical_compound, Ethers, Cyclic, Amide, Drug Discovery, Animals, Humans, Protease Inhibitors, Rats, Wistar, Molecular Biology, Cathepsin S, chemistry.chemical_classification, Binding Sites, Molecular Structure, biology, Organic Chemistry, Aromatic amine, Active site, Amides, Cathepsins, Rats, Zinc, Enzyme, chemistry, Enzyme inhibitor, biology.protein, Molecular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::276391e649721dacf1ccba01f3182ee4
https://doi.org/10.1016/j.bmcl.2006.07.033

المؤلفون: Monique Vallee, Robert Purdy, Lee R. Hagey, Gary Siuzdak, Kelly Chatman, Thomas Hollenbeck, Friedbert Weiss

المصدر: Analytical Chemistry. 71:2358-2363

مصطلحات موضوعية: Male, Detection limit, Electrospray, Chloroform, Chromatography, medicine.medical_treatment, Tandem mass spectrometry, Mass spectrometry, Mass Spectrometry, Analytical Chemistry, Steroid, chemistry.chemical_compound, chemistry, Solvents, medicine, Humans, Female, Steroids, Diethyl ether, Quantitative analysis (chemistry), Chromatography, High Pressure Liquid

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd17369dce28e443658d9912fbe2d688
https://doi.org/10.1021/ac9806411

المؤلفون: Chun Li, Véronique Dartois, Jeanette Wu, Suzanne Skolnik, Thierry T. Diagana, Thomas H. Keller, Advait Nagle, David Plouffe, Maria Tan, Matthias Rottmann, Xuena Lin, Arnab K. Chatterjee, Jonathan Chang, Elizabeth A. Winzeler, Suresh B. Lakshminarayana, Fenghua Liu, Kerstin Gagaring, John Isbell, Tao Wu, William Tan, Christopher Caldwell, Richard Glynne, Zhong Chen, Christoph Fischli, David C. Tully, Anne Goh, Tove Tuntland, Min Low Kang, Nicole Y. Ye, Jared Ek, Reto Brun, Hui Qing Ang, Rachel Borboa, Thomas Hollenbeck, Jianling Wang, Peiting Zeng, Kelli L. Kuhen, Caroline Francek

المصدر: Journal of medicinal chemistry. 54(14)

مصطلحات موضوعية: Plasmodium berghei, Plasmodium falciparum, Drug Resistance, Parasitemia, Pharmacology, Piperazines, Cell Line, chemistry.chemical_compound, Antimalarials, Inhibitory Concentration 50, Mice, Structure-Activity Relationship, In vivo, Drug Discovery, parasitic diseases, medicine, Benzene Derivatives, Potency, Animals, Humans, Amino Acids, Mice, Inbred BALB C, Aniline Compounds, biology, Chemistry, Imidazoles, Hit to lead, medicine.disease, biology.organism_classification, Malaria, Rats, Drug development, Molecular Medicine, Female, Lead compound

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38d868962b7620c4673d34cdecd094cd
https://pubmed.ncbi.nlm.nih.gov/21644570

المؤلفون: Van Nguyen-Tran, Sarah P. Gerber, S. Renee Commerford, Peter McNamara, Chad Schwartzkopf, Beatriz N. Dardik, Yu Alice Chen, Jesper Gromada, Frederique Chaperon, Hong Liu, Sandra Teixeira, Xiaohui He, H. Martin Seidel, Anneliese L. Jaton, Thomas Hollenbeck, Laura H. Jacobson

المصدر: Naunyn-Schmiedeberg's archives of pharmacology. 384(6)

مصطلحات موضوعية: Male, medicine.medical_specialty, Cannabinoid receptor, Drug Inverse Agonism, medicine.medical_treatment, Sleep, REM, Pyrimidinones, Pharmacology, Motor Activity, Extinction, Psychological, Rats, Sprague-Dawley, Mice, Rimonabant, Piperidines, Receptor, Cannabinoid, CB1, Internal medicine, medicine, Inverse agonist, Animals, Tissue Distribution, Obesity, Receptor, Dose-Response Relationship, Drug, Chemistry, Antagonist, Brain, General Medicine, Rats, Mice, Inbred C57BL, Macaca fascicularis, Endocrinology, Pyrazoles, Cannabinoid, Diet-induced obese, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f77bce869ee802cf335483dc176bafc2
https://pubmed.ncbi.nlm.nih.gov/21947251

المؤلفون: Tove Tuntland, Thomas Hollenbeck, Jennifer L. Harris, Guo Jianhua, Ross Russo, Hong Liu, Jun Li, Arnab K. Chatterjee, Perry Gordon, Jonathan Chang, David C. Tully, Christine Tumanut, Robert Epple, Jennifer A. Williams, Michael J. Roberts

المصدر: Bioorganicmedicinal chemistry letters. 17(10)

مصطلحات موضوعية: Male, medicine.drug_class, Stereochemistry, Peptidomimetic, Clinical Biochemistry, Pharmaceutical Science, Carboxamide, Biochemistry, Chemical synthesis, Structure-Activity Relationship, Drug Discovery, medicine, Animals, Protease Inhibitors, Rats, Wistar, Molecular Biology, Cathepsin S, chemistry.chemical_classification, biology, Molecular Structure, Organic Chemistry, Succinates, Cysteine protease, Amides, Cathepsins, Bioavailability, Rats, Enzyme, chemistry, Enzyme inhibitor, Drug Design, biology.protein, Molecular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b2999bae138c09ea96496905066a915
https://pubmed.ncbi.nlm.nih.gov/17382545