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1دورية أكاديمية
المؤلفون: Thomas J. M. Michiels, Wichard Tilstra, Martin R. J. Hamzink, Justin W. de Ridder, Maarten Danial, Hugo D. Meiring, Gideon F. A. Kersten, Wim Jiskoot, Bernard Metz
المصدر: Vaccines, Vol 8, Iss 4, p 712 (2020)
مصطلحات موضوعية: degradomics, mass spectrometry, tetanus toxoid, vaccines, proteomics, 3Rs, Medicine
وصف الملف: electronic resource
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المؤلفون: Hugo D. Meiring, Madelief A van Veen, Gideon F.A. Kersten, Wim Jiskoot, Bernard Metz, Thomas J M Michiels
المصدر: Journal of the American Society for Mass Spectrometry
Journal of the American Society for Mass Spectrometry, 32(6), 1490-1497مصطلحات موضوعية: Diphtheria Toxoid, 010402 general chemistry, Tandem mass tag, Proteomics, 01 natural sciences, proteomics, Structural Biology, In vivo, Tandem Mass Spectrometry, enzyme kinetics, tandem mass tag multiplexing, Enzyme kinetics, Spectroscopy, Diphtheria toxin, Chromatography, Antigen processing, Chemistry, 010401 analytical chemistry, Toxoid, In vitro toxicology, degradomics, Temperature, 0104 chemical sciences, vaccine quality control, Peptides, Research Article
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المؤلفون: Hugo D. Meiring, Thomas J M Michiels, Christian Schöneich, Gideon F.A. Kersten, Martin R.J. Hamzink, Bernard Metz, Wim Jiskoot
المصدر: Molecular Pharmaceutics. 17:4375-4385
مصطلحات موضوعية: Aldehydes, Magnetic Resonance Spectroscopy, Molecular Structure, Chemistry, Lysine, Toxoid, Formaldehyde, Cytochromes c, Pharmaceutical Science, Methylation, Lysine residue, Mass Spectrometry, Kinetics, chemistry.chemical_compound, Cross-Linking Reagents, Vaccines, Inactivated, Biochemistry, Antigen, Deamination, Drug Discovery, Posttranslational modification, Molecular Medicine, Peptides, Chromatography, High Pressure Liquid
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المصدر: Scientific Reports, 10(1), 11535
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)مصطلحات موضوعية: 0301 basic medicine, Cellular immunity, Proteases, Proteolysis, Glycine, lcsh:Medicine, Endosomes, Lactoglobulins, 01 natural sciences, Mass Spectrometry, Article, 03 medical and health sciences, Formaldehyde, medicine, Escherichia coli, Animals, Humans, Bovine serum albumin, Antigens, lcsh:Science, Cathepsin S, Cathepsin, Multidisciplinary, biology, medicine.diagnostic_test, Chemistry, 010401 analytical chemistry, lcsh:R, Proteolytic enzymes, Cytochromes c, Serum Albumin, Bovine, Cathepsins, 0104 chemical sciences, Kinetics, 030104 developmental biology, Biochemistry, biology.protein, Solvents, lcsh:Q, Cattle, Lysosomes, Peptides, Chromatography, Liquid, Chemical modification
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7cbab4c86105ab032338d0ba458f59d
http://hdl.handle.net/1887/136374 -
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المؤلفون: Daan van der Es, Laura H. Heitman, Euan Gordon, Adriaan P. IJzerman, Thomas J M Michiels, Marjolein Soethoudt, Xue Yang, Niek Dekker, Coen de Jong, Mario van der Stelt
المصدر: Journal of Medicinal Chemistry, 61(17), 7892-7901. AMER CHEMICAL SOC
Journal of Medicinal Chemistryمصطلحات موضوعية: 0301 basic medicine, Fluorophore, Chemistry, HEK 293 cells, Adenosine A2A receptor, Adenosine, Cell membrane, 03 medical and health sciences, chemistry.chemical_compound, 030104 developmental biology, medicine.anatomical_structure, Drug Discovery, medicine, Biophysics, Molecular Medicine, Molecular probe, Receptor, medicine.drug, G protein-coupled receptor
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8f443b4052b33998d24be7efdee3854
https://hdl.handle.net/1887/67709 -
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المؤلفون: Xue, Yang, Thomas J M, Michiels, Coen, de Jong, Marjolein, Soethoudt, Niek, Dekker, Euan, Gordon, Mario, van der Stelt, Laura H, Heitman, Daan, van der Es, Adriaan P, IJzerman
المصدر: Journal of medicinal chemistry. 61(17)
مصطلحات موضوعية: Adenosine, HEK293 Cells, Receptor, Adenosine A2A, Molecular Probes, Cell Membrane, Humans, Ligands, Adenosine A2 Receptor Antagonists, Receptors, G-Protein-Coupled
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المؤلفون: Wim Jiskoot, Wichard Tilstra, Gideon F.A. Kersten, Maarten Danial, Hugo D. Meiring, Martin R.J. Hamzink, Bernard Metz, Thomas J M Michiels, Justin W. de Ridder
المصدر: Vaccines
Volume 8
Issue 4
Vaccines, Vol 8, Iss 712, p 712 (2020)مصطلحات موضوعية: 0301 basic medicine, Immunology, lcsh:Medicine, complex mixtures, 01 natural sciences, Article, 3Rs, 03 medical and health sciences, proteomics, Antigen, In vivo, Drug Discovery, medicine, Potency, Pharmacology (medical), quality control, mass spectrometry, Pharmacology, Chromatography, Chemistry, Tetanus, Immunogenicity, Diphtheria, lcsh:R, 010401 analytical chemistry, degradomics, Toxoid, In vitro toxicology, vaccines, medicine.disease, 0104 chemical sciences, 3. Good health, 030104 developmental biology, Infectious Diseases, tetanus toxoid
وصف الملف: application/pdf
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المؤلفون: Thomas J M Michiels, Laura H. Heitman, Xue Yang, Julien Louvel, Ad P. IJzerman, Eelke B. Lenselink, Guo Dong
المصدر: Purinergic signalling, 13(2), 191-201
Purinergic Signalling, 13(2), 191-201. SPRINGER
Purinergic Signalling, 13(2), 191-201
Purinergic signallingمصطلحات موضوعية: 0301 basic medicine, Adenosine, Stereochemistry, A2A adenosine receptor, Covalent antagonist, 03 medical and health sciences, Cellular and Molecular Neuroscience, 0302 clinical medicine, G protein-coupled receptors, Radioligand binding, medicine, Receptor, Molecular Biology, G protein-coupled receptor, chemistry.chemical_classification, Chemistry, Cell Biology, A(2A) adenosine receptor, Ligand (biochemistry), Adenosine receptor, Amino acid, 030104 developmental biology, Docking (molecular), Covalent bond, 030220 oncology & carcinogenesis, medicine.drug
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::313d0b8828eaed6bc6f96956526f217f
https://hdl.handle.net/1887/64259 -
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المؤلفون: Xue, Yang, Guo, Dong, Thomas J M, Michiels, Eelke B, Lenselink, Laura, Heitman, Julien, Louvel, Ad P, IJzerman
المصدر: Purinergic Signalling
مصطلحات موضوعية: Adenosine, Receptor, Adenosine A2A, G protein-coupled receptors, Radioligand binding, Triazines, A2A adenosine receptor, Humans, Original Article, Triazoles, Adenosine A2 Receptor Antagonists, Covalent antagonist