المؤلفون: Long-Sheng Chang, Janet L Oblinger, Abbi E Smith, Marc Ferrer, Steven P Angus, Eric Hawley, Alejandra M Petrilli, Roberta L Beauchamp, Lars Björn Riecken, Serkan Erdin, Ming Poi, Jie Huang, Waylan K Bessler, Xiaohu Zhang, Rajarshi Guha, Craig Thomas, Sarah S Burns, Thomas S K Gilbert, Li Jiang, Xiaohong Li, Qingbo Lu, Jin Yuan, Yongzheng He, Shelley A H Dixon, Andrea Masters, David R Jones, Charles W Yates, Stephen J Haggarty, Salvatore La Rosa, D Bradley Welling, Anat O Stemmer-Rachamimov, Scott R Plotkin, James F Gusella, Justin Guinney, Helen Morrison, Vijaya Ramesh, Cristina Fernandez-Valle, Gary L Johnson, Jaishri O Blakeley, D Wade Clapp, Synodos for NF2 Consortium

المصدر: PLoS ONE, Vol 16, Iss 7, p e0252048 (2021)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/d5cdd322a442449ebaffcbfad82ea6a3

المؤلفون: Amanda B. Wass, Benjamin A. Krishna, Laura E. Herring, Thomas S. K. Gilbert, Masatoshi Nukui, Ian J. Groves, Abigail L. Dooley, Katherine H. Kulp, Stephen M. Matthews, Daniel M. Rotroff, Lee M. Graves, Christine M. O’Connor

المساهمون: Wass, Amanda B [0000-0001-7712-6259], Krishna, Benjamin A [0000-0003-0919-2961], Herring, Laura E [0000-0003-4496-7312], Gilbert, Thomas SK [0000-0002-6833-6788], Groves, Ian J [0000-0001-8882-6701], Kulp, Katherine H [0000-0003-1908-1843], Matthews, Stephen M [0000-0002-8968-225X], Rotroff, Daniel M [0000-0003-0553-3220], Graves, Lee M [0000-0002-4736-9855], O'Connor, Christine M [0000-0003-4943-3774], Apollo - University of Cambridge Repository

المصدر: Science advances. 8(43)

مصطلحات موضوعية: 3204 Immunology, 2 Aetiology, Multidisciplinary, Infectious Diseases, 2.1 Biological and endogenous factors, 32 Biomedical and Clinical Sciences, 3 Good Health and Well Being, FOS: Health sciences, Infection, Cancer

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f93e1d0061679bf7a84eafd11954e210
https://pubmed.ncbi.nlm.nih.gov/36288299

المؤلفون: Lucas J. Aponte-Collazo, Emily M. J. Fennell, Michael P. East, Thomas S. K. Gilbert, Paul R. Graves, Hani Ashamalla, Edwin J. Iwanowicz, Yoshimi Endo Greer, Stanley Lipkowitz, Lee M. Graves

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::cd238406dd7c3c8c2c59ead2d7c8c437
https://doi.org/10.1101/2022.07.11.499620

المؤلفون: Denis O Okumu, Michael P East, Merlin Levine, Laura E Herring, Raymond Zhang, Thomas S K Gilbert, David W Litchfield, Yanping Zhang, Lee M Graves

المصدر: PLoS ONE, Vol 12, Iss 5, p e0177871 (2017)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC5433768?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/6e9e1d2a1f244c7991f978e4459d5e18

المؤلفون: Paul R. Graves, Lucas J. Aponte-Collazo, Emily M. J. Fennell, Adam C. Graves, Andrew E. Hale, Nedyalka Dicheva, Laura E. Herring, Thomas S. K. Gilbert, Michael P. East, Ian M. McDonald, Matthew R. Lockett, Hani Ashamalla, Nathaniel J. Moorman, Donald S. Karanewsky, Edwin J. Iwanowicz, Ekhson Holmuhamedov, Lee M. Graves

المصدر: ACS Chemical Biology. 17:2377-2378

مصطلحات موضوعية: Molecular Medicine, General Medicine, Biochemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::15ec58c9576adc0b639bb2c10daa3347
https://doi.org/10.1021/acschembio.2c00545

المؤلفون: Justus M. Huelse, Dehui Zhang, Michael J. Miley, Rebecca E. Parker, Chenxiao Da, Lee M. Graves, H. Shelton Earp, Stephen V. Frye, Madeline G. Huey, Laura E. Herring, Dmitri Kireev, Xiaodong Wang, Michael A. Stashko, Douglas K. Graham, Jacqueline Norris-Drouin, Thomas S. K. Gilbert, Katherine A. Minson, Deborah DeRyckere, Debra Hunter, Eleana Vasileiadi

المصدر: J Am Chem Soc

مصطلحات موضوعية: Protein family, Cell Survival, Antineoplastic Agents, 010402 general chemistry, 01 natural sciences, Biochemistry, Article, Catalysis, Mice, Colloid and Surface Chemistry, Cell Line, Tumor, Animals, Humans, Amino Acid Sequence, Regulation of gene expression, Molecular Structure, Chemistry, Receptor Protein-Tyrosine Kinases, Myeloid leukemia, Neoplasms, Experimental, General Chemistry, MERTK, Phenotype, 0104 chemical sciences, Gene Expression Regulation, Neoplastic, Cell culture, Cancer research, Tyrosine kinase, TYRO3

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a56601afc98511d1e107788dc4625c46
https://doi.org/10.1021/jacs.9b08660

المؤلفون: Salvatore La Rosa, Helen Morrison, Jie Huang, Rajarshi Guha, Li Jiang, Yongzheng He, Gary L. Johnson, Steven P. Angus, Eric T. Hawley, Vijaya Ramesh, Justin Guinney, Sarah S. Burns, Jin Yuan, Roberta L. Beauchamp, Lars Björn Riecken, Cristina Fernandez-Valle, Marc Ferrer, Charles W. Yates, Serkan Erdin, Abbi Smith, Waylan K. Bessler, D. Bradley Welling, D. Wade Clapp, Shelley Dixon, Scott R. Plotkin, Ming Poi, Thomas S. K. Gilbert, Anat Stemmer-Rachamimov, Alejandra M. Petrilli, Craig J. Thomas, Xiaohong Li, Qingbo Lu, David R. Jones, James F. Gusella, Long-Sheng Chang, Andrea R. Masters, Xiaohu Zhang, Janet L. Oblinger, Jaishri O. Blakeley, Stephen J. Haggarty

المصدر: PLoS ONE
PLoS ONE, Vol 16, Iss 7, p e0252048 (2021)

مصطلحات موضوعية: 0301 basic medicine, Macroglial Cells, Cancer Treatment, Schwannoma, Biochemistry, Tyrosine Kinases, 0302 clinical medicine, Medical Conditions, Animal Cells, Medicine and Health Sciences, Meningeal Neoplasms, Kinome, Neurofibromatosis type 2, Neurological Tumors, Neurofibromin 2, Multidisciplinary, Pharmaceutics, Animal Models, Protein-Tyrosine Kinases, EPH receptor A2, Enzymes, Oncology, Neurology, Experimental Organism Systems, Genetic Diseases, 030220 oncology & carcinogenesis, Medicine, Cellular Types, Meningioma, Tyrosine kinase, Neurilemmoma, Research Article, Brigatinib, Tumor suppressor gene, Science, Mouse Models, Glial Cells, Research and Analysis Methods, 03 medical and health sciences, Model Organisms, Organophosphorus Compounds, Drug Therapy, medicine, otorhinolaryngologic diseases, Humans, neoplasms, Cell Proliferation, Clinical Genetics, business.industry, Autosomal Dominant Diseases, Cancers and Neoplasms, Biology and Life Sciences, Proteins, Cell Biology, medicine.disease, nervous system diseases, 030104 developmental biology, Pyrimidines, Neurofibromatosis Type 2, Mutation, Cancer research, Animal Studies, Enzymology, Schwann Cells, business, Protein Kinases

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3305e5677c3612913a49faf5250fc4e0
http://europepmc.org/articles/PMC8282008

المؤلفون: Bjoern Papke, Z. D. Kaiser, Mariaelena Pierobon, Richard G. Hodge, J. N. Diehl, Runying Yang, Thomas S. K. Gilbert, E. Petricoin, Naim U. Rashid, Devon R. Blake, Laura E. Herring, K. R. Snare, Elisa Baldelli, Priya S. Hibshman, Lee M. Graves, Channing J. Der, Jennifer E. Klomp, Adrienne D. Cox

مصطلحات موضوعية: MAPK/ERK pathway, endocrine system diseases, Kinase, Biology, medicine.disease_cause, PLK1, digestive system diseases, Wee1, Cancer research, biology.protein, medicine, Kinome, KRAS, Kinase activity, neoplasms, Proto-oncogene tyrosine-protein kinase Src

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::25c42dee576909ed89088756f8fc5656
https://doi.org/10.1101/2021.04.27.441678

المؤلفون: Kevin S. Kapner, William C. Hahn, Nanyun Tang, Hongwei H. Yin, Kaisheng Chen, Michelle Kassner, Bjoern Papke, Thomas S. K. Gilbert, A. Cole Edwards, J. Nathaniel Diehl, Sehrish Javaid, Tala O. Khatib, Devon R. Blake, Kajal R. Grover, James M. McFarland, Katherine H. Walsh, Tikvah K. Hayes, Manpreet Kalkat, Katherine M. Nowak, Channing J. Der, G. Aaron Hobbs, Olga Tanaseichuk, Adele Waters, Lee M. Graves, Antje Schaefer, Adrienne D. Cox, Clint A. Stalnecker, Linda Z. Penn, Craig M. Goodwin, Anna Barkovskaya, Andrew J. Aguirre, Priya S. Hibshman, Jennifer E. Klomp, Yingyao Zhou, Laura E. Herring, Rita Sulahian, Runying Yang

المصدر: Cell reports
Cell Reports, Vol 35, Iss 13, Pp 109291-(2021)

مصطلحات موضوعية: 0301 basic medicine, MAPK/ERK pathway, Small interfering RNA, Transcription, Genetic, Pyridines, pancreatic cancer, Apoptosis, MYC, medicine.disease_cause, Microtubules, 0302 clinical medicine, Tubulin, Acetamides, Biology (General), Extracellular Signal-Regulated MAP Kinases, p130Cas, Chemistry, Calpain, Drug Synergism, Gene Expression Regulation, Neoplastic, Organoids, ERK, src-Family Kinases, Phosphorylation, KRAS, Proto-oncogene tyrosine-protein kinase Src, Half-Life, QH301-705.5, Morpholines, Down-Regulation, General Biochemistry, Genetics and Molecular Biology, Article, Proto-Oncogene Proteins c-myc, Proto-Oncogene Proteins p21(ras), 03 medical and health sciences, Pancreatic cancer, Cell Line, Tumor, medicine, Humans, Protein Kinase Inhibitors, Cell Proliferation, TUBB3, medicine.disease, Xenograft Model Antitumor Assays, Pancreatic Neoplasms, 030104 developmental biology, Crk-Associated Substrate Protein, BCAR1, Mutation, Cancer research, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa70e97d6bf8eeb43a46832a616c256d
https://pubmed.ncbi.nlm.nih.gov/34192548

المؤلفون: Kris C. Wood, Thomas S. K. Gilbert, Lee M. Graves, Emanuel F. Petricoin, Onur Dagliyan, Samuel D. George, Antje Schaefer, Mariaelena Pierobon, Kathleen Klotz-Noack, Bjoern Papke, Ramon V. Tiu, Channing J. Der, Krister Wennerberg, Adrienne D. Cox, Nhan L. Tran, Adele Waters, J. Nathaniel Diehl, Craig M. Goodwin, Kevin H. Lin, Prson Gautam, Shripad V. Bhagwat, Irem Ozkan-Dagliyan, Sen Peng, Laura E. Herring, Christine Sers, Sheng Bin Peng

المساهمون: Computational Systems Medicine, Institute for Molecular Medicine Finland, University of Helsinki, Krister Wennerberg / Principal Investigator

المصدر: Cell Reports, Vol 31, Iss 11, Pp 107764-(2020)
Cell reports

مصطلحات موضوعية: 0301 basic medicine, MAPK/ERK pathway, Mutant, Apoptosis, MYC, FOSL1, medicine.disease_cause, Transcriptome, 0302 clinical medicine, mesenchymal-to-epithelial transition, PHOSPHORYLATION, lcsh:QH301-705.5, Chemistry, Reverse phase protein lysate microarray, COMBINED BRAF, PANCREATIC-CANCER, 3. Good health, C-RAF, ERK, KRAS, Carcinoma, Pancreatic Ductal, Signal Transduction, MAP Kinase Signaling System, CELL LUNG-CANCER, ONCOGENIC KRAS, General Biochemistry, Genetics and Molecular Biology, Article, Proto-Oncogene Proteins p21(ras), SIGNALING PATHWAYS, 03 medical and health sciences, Cell Line, Tumor, medicine, Animals, Humans, Protein Kinase Inhibitors, Mitogen-Activated Protein Kinase Kinases, RAF, DEGRADATION, digestive system diseases, ADAPTIVE RESISTANCE, Pancreatic Neoplasms, 030104 developmental biology, lcsh:Biology (General), Mutation, Cancer research, 1182 Biochemistry, cell and molecular biology, ENRICHMENT, Proto-Oncogene Proteins c-akt, 030217 neurology & neurosurgery, Genetic screen

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::550df40f3803c5f9c802f23c624dc395
http://hdl.handle.net/10138/317792