المؤلفون: Thorsten Rosner, Jun Li, Andrew T. Parsons, Charles Pathirana, James R. Sawyer, Thomas E. La Cruz, Joerg Deerberg, Alicia T. Ng, Antonio Ramirez, Kristy Tran, Omid Soltani, Eric M. Simmons, Yu Fan, Jacob M. Janey, Neil A. Strotman

المصدر: The Journal of Organic Chemistry. 83:11133-11144

مصطلحات موضوعية: Ketone, Chemistry Techniques, Synthetic, 010402 general chemistry, Ring (chemistry), 01 natural sciences, Catalysis, Kinetic resolution, Stereocenter, Density Functional Theory, chemistry.chemical_classification, Aniline Compounds, 010405 organic chemistry, Chemistry, Alkene, Organic Chemistry, Enantioselective synthesis, Substrate (chemistry), Stereoisomerism, Ketones, Combinatorial chemistry, 0104 chemical sciences, Kinetics, Pyrimidines, Cyclization, Hydrogenation, Amyloid Precursor Protein Secretases, Oxidation-Reduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bdee34db6719cca004cd74ec773d7e4
https://doi.org/10.1021/acs.joc.8b01734

المؤلفون: Thomas M. Razler, Jianji Wang, Yi Hsiao, Yuping Qiu, Thorsten Rosner, Kolotuchin Sergei, Carolyn S. Wei, Carrasquillo Ronald, Andrew G. Lee, Brendan Mack, Paul C. Lobben, Jacob M. Janey, Zhongping Shi, Eric M. Simmons, Jason M. Stevens, Xinhua Qian, Eric C. Huang, Federico Lora-Gonzalez, Thomas La Porte, Steven R. Wisniewski, Geng Peng, Gregory L. Beutner, Boguslaw Mudryk, Kishta Katipally, Ye Zhu, Antonio Ramirez

المصدر: Organic Letters. 20:3736-3740

مصطلحات موضوعية: inorganic chemicals, Active ingredient, Atropisomer, 010405 organic chemistry, Chemistry, Stereochemistry, organic chemicals, Organic Chemistry, Total synthesis, 010402 general chemistry, 01 natural sciences, Biochemistry, 0104 chemical sciences, Physical and Theoretical Chemistry, Chirality (chemistry)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b68020a70953f67cf64673382d9733e
https://doi.org/10.1021/acs.orglett.8b01218

المؤلفون: Amy Newton, Joanna Hu, Thorsten Rosner, George O. Tora, Yu-Wen Li, Joseph Raybon, Yi Hsiao, Xiaoping Hou, Joanne J. Bronson, Nicholas J. Lodge, John E. Macor, David A. Conlon, Carl D. Davis, Jung-Hui Sun, Michael K. Wong, Kevin W. Gillman, Sarah J. Taylor, Umesh Hanumegowda, Rudolph G. Krause, Huiping Zhang, Hong Huang, Matthew T. Taber, Andrew P. Degnan, Rick L. Pieschl

المصدر: ACS Chemical Neuroscience. 7:1635-1640

مصطلحات موضوعية: 0301 basic medicine, Indazoles, Physiology, Cognitive Neuroscience, hERG, Drug Evaluation, Preclinical, Administration, Oral, Pharmacology, Biochemistry, Mice, Structure-Activity Relationship, 03 medical and health sciences, 0302 clinical medicine, Neurokinin-1 Receptor Antagonists, Transcriptional Regulator ERG, In vivo, Drug Discovery, Animals, Humans, Serotonin Uptake Inhibitors, Receptor, Serotonin transporter, Serotonin Plasma Membrane Transport Proteins, Depressive Disorder, Dose-Response Relationship, Drug, Molecular Structure, biology, Drug discovery, Chemistry, Cell Biology, General Medicine, Receptors, Neurokinin-1, Antidepressive Agents, Rats, Disease Models, Animal, 030104 developmental biology, biology.protein, Gerbillinae, Reuptake inhibitor, Selective Serotonin Reuptake Inhibitors, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d6fa37d587f9db97c4c47bad7b33ffb
https://doi.org/10.1021/acschemneuro.6b00337

المؤلفون: Richard J. Fox, Michael B. Hay, Gregory L. Beutner, Keming Zhu, Carolyn S. Wei, Lopa Bakrania, Cuniere Nicolas, Christopher S. Regens, Fanfair Dayne Dustan, Martin D. Eastgate, Chester E. Markwalter, Kristy Tran, Neil A. Strotman, Yi Hsiao, Michael Lawler, Maxime Soumeillant, Dimitri Skliar, Thorsten Rosner, Benjamin M. Cohen, Paul C. Lobben

المصدر: The Journal of organic chemistry. 84(8)

مصطلحات موضوعية: Molecular Structure, 010405 organic chemistry, Longest linear sequence, Chemistry, Organic Chemistry, Janus Kinase 2, 010402 general chemistry, Ligands, 01 natural sciences, Combinatorial chemistry, Catalysis, 0104 chemical sciences, JAK2 Inhibitor BMS-911543, chemistry.chemical_compound, Molecule, Imidazole, Humans, Heterocyclic Compounds, 3-Ring, Protein Kinase Inhibitors, Palladium, Pyrrole

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2f077ef70cb94bf27825edbeeef9c53
https://pubmed.ncbi.nlm.nih.gov/30388009

المؤلفون: Daniel G.M. Roberts, Daniel S. Hsieh, Thorsten Rosner, Chiajen Lai, Tamar Rosenbaum, Qi Gao

المصدر: Crystal Growth & Design. 16:12-24

مصطلحات موضوعية: 010405 organic chemistry, Chemistry, Enthalpy of fusion, Thermodynamics, General Chemistry, Calorimetry, 010402 general chemistry, Condensed Matter Physics, Thermodynamic equations, 01 natural sciences, Heat capacity, 0104 chemical sciences, Gibbs free energy, Enthalpy change of solution, symbols.namesake, symbols, Melting point, General Materials Science, Solubility

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d6991e7a7007b0c419917330212afd95
https://doi.org/10.1021/acs.cgd.5b00443

المؤلفون: Jaume Balsells, Edward J. J. Grabowski, Shane W. Krska, Nelo R. Rivera, Yongkui Sun, Joseph D. Armstrong, Bryon Simmons, Andrew M. Clausen, Felix Spindler, Yi Hsiao, Michele Kubryk, Christophe Malan, Karl B. Hansen, Nori Ikemoto, Feng Xu, Thorsten Rosner

المصدر: Journal of the American Chemical Society. 142:13622-13622

مصطلحات موضوعية: Colloid and Surface Chemistry, Chemistry, Sitagliptin, medicine, Enantioselective synthesis, General Chemistry, Biochemistry, Combinatorial chemistry, Catalysis, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ff28a025888c0453761a46c2fa910f8b
https://doi.org/10.1021/jacs.0c06041

المؤلفون: Fanfair Dayne Dustan, David K. Leahy, Yi Hsiao, Carolyn S. Wei, Thorsten Rosner, Lopa V. Desai, Michael B. Hay

المصدر: Tetrahedron. 69:5677-5684

مصطلحات موضوعية: chemistry.chemical_classification, Imagination, Ketone, Chemical substance, media_common.quotation_subject, Organic Chemistry, chemistry.chemical_element, Biochemistry, Catalysis, Search engine, chemistry, Drug Discovery, Organic chemistry, Weak base, Science, technology and society, Palladium, media_common

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::83942dea099ddd92d20fe014c2f526c3
https://doi.org/10.1016/j.tet.2013.04.057

المؤلفون: Ling Chen, Qi Gao, Zhiwei Guo, Masano Sugiyama, Cuniere Nicolas, Lopa V. Desai, Jason Zhu, Yi Hsiao, Thorsten Rosner, Yu Fan, Collin Chan, David K. Leahy, Guanglin Luo, Ronald L. Hanson

المصدر: Organic Letters. 14:4938-4941

مصطلحات موضوعية: Molecular Structure, Stereochemistry, Chemistry, Calcitonin Gene-Related Peptide, Organic Chemistry, Antagonist, Enantioselective synthesis, Stereoisomerism, Calcitonin gene-related peptide, Heterocyclic Compounds, 4 or More Rings, Biochemistry, Combinatorial chemistry, Catalysis, Physical and Theoretical Chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::702037661a40da959f209ef00178f87a
https://doi.org/10.1021/ol302262q

المؤلفون: Martin D. Eastgate, Yuping Qiu, R. Erik Plata, Donna G. Blackmond, Geng Peng, Yi Hsiao, Thomas M. Razler, Michael A. Schmidt, Yining Ji, Thorsten Rosner, Michael B. Hay, Christopher S. Regens

المصدر: Journal of the American Chemical Society. 137(41)

مصطلحات موضوعية: Denticity, Magnetic Resonance Spectroscopy, Chemistry, Ligand, Xantphos, Phosphines, General Chemistry, Photochemistry, Crystallography, X-Ray, Biochemistry, Oxidative addition, Medicinal chemistry, Catalysis, Reaction rate, chemistry.chemical_compound, Kinetics, Colloid and Surface Chemistry, Xanthenes, Carboxylate, Oxidation-Reduction, Phosphine, Palladium

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ac45b55cd2b0993afd04e98e9dde277
https://pubmed.ncbi.nlm.nih.gov/26461028

المؤلفون: Yongkui Sun, Thorsten Rosner, Scott Shultz, Wes Schafer, Xiaoyi Gong, Leonard William, Peter Sajonz, Christopher J. Welch

المصدر: Journal of Liquid Chromatography & Related Technologies. 31:2296-2304

مصطلحات موضوعية: Chromatography, Chemistry, Process development, Process research, Clinical Biochemistry, Microfluidics, Enantioselective synthesis, Pharmaceutical Science, Biochemistry, High-performance liquid chromatography, Method development, Analytical Chemistry, Throughput (business), Catalytic hydrogenation

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::591b84c52a7dd1f07a848150b381080b
https://doi.org/10.1080/10826070802281653