يعرض 1 - 2 نتائج من 2 نتيجة بحث عن '"Thrombopoiesis genetics"', وقت الاستعلام: 0.88s تنقيح النتائج
  1. 1
    A novel signalling screen demonstrates that CALR mutations activate essential MAPK signalling and facilitate megakaryocyte differentiation

    المؤلفون: K Kollmann, W Warsch, C Gonzalez-Arias, F L Nice, E Avezov, J Milburn, J Li, D Dimitropoulou, S Biddie, M Wang, E Poynton, M Colzani, M R Tijssen, S Anand, U McDermott, B Huntly, T Green

    المساهمون: Avezov, Edward [0000-0002-2894-0585], Huntly, Brian [0000-0003-0312-161X], Green, Tony [0000-0002-9795-0218], Apollo - University of Cambridge Repository

    المصدر: Kollmann, K, Warsch, W, Gonzalez-Arias, C, Nice, F L, Avezov, E, Milburn, J, Li, J, Dimitropoulou, D, Biddie, S, Wang, M, Poynton, E, Colzani, M, Tijssen, M R, Anand, S, McDermott, U, Huntly, B & Green, T 2017, ' A novel signalling screen demonstrates that CALR mutations activate essential MAPK signalling and facilitate megakaryocyte differentiation ', Leukemia, vol. 31, no. 4, pp. 934-944 . https://doi.org/10.1038/leu.2016.280
    Leukemia

    مصطلحات موضوعية: Protein Stability, Thrombopoiesis/genetics, ras Proteins/genetics, Cell Differentiation, Megakaryocytes/cytology, Cell Line, Proteasome Endopeptidase Complex/metabolism, Fetal Blood/cytology, Janus Kinase 2/antagonists & inhibitors, Protein Kinase Inhibitors/pharmacology, Signal Transduction/drug effects, StemCellInstitute, Calreticulin/antagonists & inhibitors, Drug Discovery, Mutation, Proto-Oncogene Proteins B-raf/genetics, Humans, Ectopic Gene Expression/drug effects, Mitogen-Activated Protein Kinases/metabolism, Antigens, CD34/metabolism

    وصف الملف: application/pdf

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::64fc6363344fd1a5c016cf0ddbaeb804
    https://www.repository.cam.ac.uk/handle/1810/261276

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  2. 2
    دورية أكاديمية
    Ets-dependent regulation of target gene expression during megakaryopoiesis

    المؤلفون: Jackers, Pascale, Szalai, Gabor, Moussa, Omar, Watson, Dennis K

    المساهمون: Hollings Cancer Center, Medical University of South Carolina, USA

    المصدر: Journal of Biological Chemistry, 279 (50), 52183-52190 (2004-12-10)

    مصطلحات موضوعية: Base Sequence, Cell Line, DNA/genetics, DNA-Binding Proteins/genetics/metabolism, Erythroid-Specific DNA-Binding Factors, GATA1 Transcription Factor, Gene Expression Regulation, Genetic Markers, Humans, Integrin alpha2, Megakaryocytes/metabolism, Membrane Glycoproteins/genetics, Neoplasm Proteins/genetics, Platelet Glycoprotein GPIb-IX Complex/genetics, Promoter Regions, Genetic, Proto-Oncogene Protein c-ets-1, Proto-Oncogene Protein c-fli-1, Proto-Oncogene Proteins/genetics/metabolism, Proto-Oncogene Proteins c-ets, Receptors, Cytokine/genetics, Receptors, Thrombopoietin, Thrombopoiesis/genetics, Trans-Activators/genetics/metabolism, Transcription Factors/genetics/metabolism, Human health sciences, Oncology, Life sciences, Anatomy (cytology, histology, embryology...) & physiology, Biochemistry, biophysics & molecular biology, Genetics & genetic processes, Hematology, Sciences de la santé humaine, Oncologie, Sciences du vivant, Anatomie (cytologie, histologie, embryologie...) & physiologie, Biochimie, biophysique & biologie moléculaire, Génétique & processus génétiques, Hématologie

    Relation: urn:issn:0021-9258; urn:issn:1083-351X

    URL الوصول: https://orbi.uliege.be/handle/2268/16385

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