المؤلفون: Chomiak AA; Department of Epigenetics, Van Andel Institute, Grand Rapids, MI 49503, USA., Tiedemann RL; Department of Epigenetics, Van Andel Institute, Grand Rapids, MI 49503, USA., Liu Y; Department of Epigenetics, Van Andel Institute, Grand Rapids, MI 49503, USA., Kong X; Department of Oncology, the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Cui Y; Department of Oncology, the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Wiseman AK; Department of Epigenetics, Van Andel Institute, Grand Rapids, MI 49503, USA., Thurlow KE; Department of Epigenetics, Van Andel Institute, Grand Rapids, MI 49503, USA., Cornett EM; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indiana University, Indianapolis, IN 46202, USA., Topper MJ; Department of Oncology, the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Baylin SB; Department of Oncology, the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Rothbart SB; Department of Epigenetics, Van Andel Institute, Grand Rapids, MI 49503, USA.

المصدر: Science advances [Sci Adv] 2024 Mar 29; Vol. 10 (13), pp. eadk4423. Date of Electronic Publication: 2024 Mar 27.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2375-2548 (Electronic) Linking ISSN: 23752548 NLM ISO Abbreviation: Sci Adv Subsets: MEDLINE

مواضيع طبية MeSH: Colonic Neoplasms*/drug therapy , Colonic Neoplasms*/genetics , Enhancer of Zeste Homolog 2 Protein*/antagonists & inhibitors , Histones*/metabolism, Humans ; Methylation ; Signal Transduction ; Transcription Factor AP-1/metabolism

المؤلفون: Tiedemann RL, Hrit J, Du Q, Wiseman AK, Eden HE, Dickson BM, Kong X, Chomiak AA, Vaughan RM, Hebert JM, David Y, Zhou W, Baylin SB, Jones PA, Clark SJ, Rothbart SB

المصدر: BioRxiv : the preprint server for biology [bioRxiv] 2024 Feb 16. Date of Electronic Publication: 2024 Feb 16.

نوع المنشور: Preprint

بيانات الدورية: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

المؤلفون: Wiseman AK; Department of Epigenetics, Van Andel Institute, Grand Rapids, MI, 49503, USA., Tiedemann RL; Department of Epigenetics, Van Andel Institute, Grand Rapids, MI, 49503, USA., Fan H; Center for Precision Health, School of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, TX, 77030, USA., Shen H; Department of Epigenetics, Van Andel Institute, Grand Rapids, MI, 49503, USA., Madaj Z; Department of Epigenetics, Van Andel Institute, Grand Rapids, MI, 49503, USA., McCabe MT; Cancer Epigenetics Research Unit, Oncology R&D, GlaxoSmithKline, Collegeville, PA, USA., Pappalardi MB; Cancer Epigenetics Research Unit, Oncology R&D, GlaxoSmithKline, Collegeville, PA, USA., Jones PA; Department of Epigenetics, Van Andel Institute, Grand Rapids, MI, 49503, USA. Peter.Jones@vai.org.

المصدر: Communications biology [Commun Biol] 2022 Jun 02; Vol. 5 (1), pp. 528. Date of Electronic Publication: 2022 Jun 02.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: Electronic Cited Medium: Internet ISSN: 2399-3642 (Electronic) Linking ISSN: 23993642 NLM ISO Abbreviation: Commun Biol Subsets: MEDLINE

مواضيع طبية MeSH: DNA Methylation* , Neoplasms*/genetics, CpG Islands ; DNA ; Female ; Humans ; Male ; X Chromosome

المؤلفون: Carpenter BL; Department of Epigenetics, Van Andel Institute, Grand Rapids, MI 49503., Remba TK; Department of Epigenetics, Van Andel Institute, Grand Rapids, MI 49503., Thomas SL; Department of Epigenetics, Van Andel Institute, Grand Rapids, MI 49503., Madaj Z; Department of Epigenetics, Van Andel Institute, Grand Rapids, MI 49503., Brink L; Department of Obstetrics and Gynecology, Faculty of Medicine and Health Science, Stellenbosch University, Cape Town, Western Cape, 7530, South Africa., Tiedemann RL; Department of Epigenetics, Van Andel Institute, Grand Rapids, MI 49503., Odendaal HJ; Department of Obstetrics and Gynecology, Faculty of Medicine and Health Science, Stellenbosch University, Cape Town, Western Cape, 7530, South Africa., Jones PA; Department of Epigenetics, Van Andel Institute, Grand Rapids, MI 49503; peter.jones@vai.org.

المصدر: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2021 Mar 23; Vol. 118 (12).

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

مواضيع طبية MeSH: DNA Methylation* , Epigenesis, Genetic* , Genomic Imprinting*, Alcohol Drinking/*adverse effects , Maternal Exposure/*adverse effects , Oocytes/*metabolism , RNA, Untranslated/*genetics, Alleles ; CpG Islands ; Female ; High-Throughput Nucleotide Sequencing ; Humans ; Maternal Age ; Pregnancy

المؤلفون: Tiedemann RL; Center for Epigenetics, Van Andel Institute, Grand Rapids, MI, USA., Eden HE; Center for Epigenetics, Van Andel Institute, Grand Rapids, MI, USA., Huang Z; Center for Epigenetics, Van Andel Institute, Grand Rapids, MI, USA., Robertson KD; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, USA., Rothbart SB; Center for Epigenetics, Van Andel Institute, Grand Rapids, MI, USA. scott.rothbart@vai.org.

المصدر: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2021; Vol. 2272, pp. 97-140.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Humana Press Country of Publication: United States NLM ID: 9214969 Publication Model: Print Cited Medium: Internet ISSN: 1940-6029 (Electronic) Linking ISSN: 10643745 NLM ISO Abbreviation: Methods Mol Biol Subsets: MEDLINE

مواضيع طبية MeSH: DNA Demethylation* , DNA Methylation* , Epigenesis, Genetic*, DNA/*analysis , DNA/*chemistry , Microarray Analysis/*methods , Sulfites/*chemistry, 5-Methylcytosine/analogs & derivatives ; 5-Methylcytosine/chemistry ; Computational Biology ; Cytosine/analogs & derivatives ; Cytosine/chemistry ; DNA/genetics ; High-Throughput Nucleotide Sequencing ; Humans ; Oxidation-Reduction

المؤلفون: Franks JL; Department of Pharmacology, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.; Lineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America., Martinez-Chacin RC; Department of Pharmacology, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America., Wang X; Lineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America., Tiedemann RL; Center for Epigenetics, Van Andel Research Institute, Grand Rapids, Michigan, United States of America., Bonacci T; Lineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America., Choudhury R; Lineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America., Bolhuis DL; Department of Pharmacology, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America., Enrico TP; Department of Pharmacology, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.; Lineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America., Mouery RD; Department of Pharmacology, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.; Department of Genetics, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America., Damrauer JS; Lineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America., Yan F; Lineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America., Harrison JS; Department of Chemistry, University of the Pacific, Stockton, California, United States of America., Major MB; Department of Cell Biology and Physiology, Department of Otolaryngology, Washington University in St. Louis, St. Louis, Missouri, United States of America., Hoadley KA; Lineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.; Department of Genetics, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America., Suzuki A; McArdle Laboratory for Cancer Research, Department of Oncology, University of Wisconsin, Madison, Wisconsin, United States of America., Rothbart SB; Center for Epigenetics, Van Andel Research Institute, Grand Rapids, Michigan, United States of America., Brown NG; Department of Pharmacology, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.; Lineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America., Emanuele MJ; Department of Pharmacology, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.; Lineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.

المصدر: PLoS biology [PLoS Biol] 2020 Dec 11; Vol. 18 (12), pp. e3000975. Date of Electronic Publication: 2020 Dec 11 (Print Publication: 2020).

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101183755 Publication Model: eCollection Cited Medium: Internet ISSN: 1545-7885 (Electronic) Linking ISSN: 15449173 NLM ISO Abbreviation: PLoS Biol Subsets: MEDLINE

مواضيع طبية MeSH: Anaphase-Promoting Complex-Cyclosome/*metabolism , CCAAT-Enhancer-Binding Proteins/*metabolism , Chromatin/*metabolism , Ubiquitin-Protein Ligases/*metabolism, Anaphase-Promoting Complex-Cyclosome/physiology ; CCAAT-Enhancer-Binding Proteins/genetics ; CCAAT-Enhancer-Binding Proteins/physiology ; Cell Cycle/physiology ; Cell Cycle Proteins/metabolism ; Cell Line ; Chromatin/genetics ; Computer Simulation ; HEK293 Cells ; HeLa Cells ; Humans ; Protein Processing, Post-Translational ; Transcription Factors/metabolism ; Ubiquitin-Protein Ligases/physiology ; Ubiquitination

المؤلفون: Fan H; Center for Epigenetics, Van Andel Research Institute, Grand Rapids, MI, USA., Atiya HI; Division of Hematology/Oncology, Department of Medicine, Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA, USA., Wang Y; Department of Gynecology and Obstetrics, Department of Oncology, and Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Pisanic TR; Johns Hopkins Institute for NanoBiotechnology, Johns Hopkins University, Baltimore, MD, USA., Wang TH; Johns Hopkins Institute for NanoBiotechnology, Johns Hopkins University, Baltimore, MD, USA., Shih IM; Department of Gynecology and Obstetrics, Department of Oncology, and Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Foy KK; Center for Epigenetics, Van Andel Research Institute, Grand Rapids, MI, USA., Frisbie L; Division of Hematology/Oncology, Department of Medicine, Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA, USA., Buckanovich RJ; Division of Hematology/Oncology, Department of Medicine, Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA, USA; Division of Gynecologic Oncology, Department of Obstetrics, Gynecology, and Reproductive Sciences, Magee Women's Research Institute, University of Pittsburgh, Pittsburgh, PA, USA., Chomiak AA; Center for Epigenetics, Van Andel Research Institute, Grand Rapids, MI, USA., Tiedemann RL; Center for Epigenetics, Van Andel Research Institute, Grand Rapids, MI, USA., Rothbart SB; Center for Epigenetics, Van Andel Research Institute, Grand Rapids, MI, USA., Chandler C; Division of Gynecologic Oncology, Department of Obstetrics, Gynecology, and Reproductive Sciences, Magee Women's Research Institute, University of Pittsburgh, Pittsburgh, PA, USA., Shen H; Center for Epigenetics, Van Andel Research Institute, Grand Rapids, MI, USA. Electronic address: hui.shen@vai.org., Coffman LG; Division of Hematology/Oncology, Department of Medicine, Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA, USA; Division of Gynecologic Oncology, Department of Obstetrics, Gynecology, and Reproductive Sciences, Magee Women's Research Institute, University of Pittsburgh, Pittsburgh, PA, USA. Electronic address: coffmanl@upmc.edu.

المصدر: Cell reports [Cell Rep] 2020 Dec 08; Vol. 33 (10), pp. 108473.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE

مواضيع طبية MeSH: Epithelial-Mesenchymal Transition/*genetics , Neoplasm Metastasis/*genetics , Ovarian Neoplasms/*genetics, Animals ; Carcinoma, Ovarian Epithelial/genetics ; Carcinoma, Ovarian Epithelial/metabolism ; Carcinoma, Ovarian Epithelial/pathology ; Cell Differentiation/genetics ; Cell Line, Tumor ; Cell Movement/genetics ; Cell Proliferation/genetics ; Enhancer of Zeste Homolog 2 Protein/genetics ; Epigenome/genetics ; Epigenomics/methods ; Female ; Gene Expression/genetics ; Gene Expression Regulation, Neoplastic/genetics ; Humans ; Mesenchymal Stem Cells/physiology ; Mice ; Mice, Inbred NOD ; Ovarian Neoplasms/metabolism ; Ovarian Neoplasms/pathology ; Primary Cell Culture ; Signal Transduction/genetics ; WT1 Proteins/genetics ; WT1 Proteins/metabolism

المؤلفون: Dickson BM; Center for Epigenetics, Van Andel Research Institute, Grand Rapids, Michigan, USA. Electronic address: bradley.dickson@vai.org., Tiedemann RL; Center for Epigenetics, Van Andel Research Institute, Grand Rapids, Michigan, USA., Chomiak AA; Center for Epigenetics, Van Andel Research Institute, Grand Rapids, Michigan, USA., Cornett EM; Center for Epigenetics, Van Andel Research Institute, Grand Rapids, Michigan, USA; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana, USA., Vaughan RM; Center for Epigenetics, Van Andel Research Institute, Grand Rapids, Michigan, USA., Rothbart SB; Center for Epigenetics, Van Andel Research Institute, Grand Rapids, Michigan, USA.

المصدر: The Journal of biological chemistry [J Biol Chem] 2020 Nov 20; Vol. 295 (47), pp. 15826-15837. Date of Electronic Publication: 2020 Sep 29.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE

مواضيع طبية MeSH: Chromatin Immunoprecipitation Sequencing* , Sequence Analysis, DNA*, Humans

المؤلفون: Vaughan RM; Center for Epigenetics, Van Andel Institute, Grand Rapids, MI, 49503, USA., Kupai A; Center for Epigenetics, Van Andel Institute, Grand Rapids, MI, 49503, USA., Foley CA; Center for Integrative Chemical Biology and Drug Discovery, Division of Chemical Biology and Medicinal Chemistry, UNC Eshelman School of Pharmacy, University of North Carolina At Chapel Hill, Chapel Hill, NC, 27599, USA., Sagum CA; Department of Epigenetics and Molecular Carcinogenesis, University of Texas MD Anderson Cancer Center, Smithville, TX, 78957, USA., Tibben BM; Center for Epigenetics, Van Andel Institute, Grand Rapids, MI, 49503, USA., Eden HE; Center for Epigenetics, Van Andel Institute, Grand Rapids, MI, 49503, USA., Tiedemann RL; Center for Epigenetics, Van Andel Institute, Grand Rapids, MI, 49503, USA., Berryhill CA; Center for Epigenetics, Van Andel Institute, Grand Rapids, MI, 49503, USA., Patel V; Center for Epigenetics, Van Andel Institute, Grand Rapids, MI, 49503, USA., Shaw KM; Center for Epigenetics, Van Andel Institute, Grand Rapids, MI, 49503, USA., Krajewski K; Department of Biochemistry and Biophysics, University of North Carolina At Chapel Hill, Chapel Hill, NC, 27599, USA., Strahl BD; Department of Biochemistry and Biophysics, University of North Carolina At Chapel Hill, Chapel Hill, NC, 27599, USA., Bedford MT; Department of Epigenetics and Molecular Carcinogenesis, University of Texas MD Anderson Cancer Center, Smithville, TX, 78957, USA., Frye SV; Center for Integrative Chemical Biology and Drug Discovery, Division of Chemical Biology and Medicinal Chemistry, UNC Eshelman School of Pharmacy, University of North Carolina At Chapel Hill, Chapel Hill, NC, 27599, USA., Dickson BM; Center for Epigenetics, Van Andel Institute, Grand Rapids, MI, 49503, USA., Rothbart SB; Center for Epigenetics, Van Andel Institute, Grand Rapids, MI, 49503, USA. scott.rothbart@vai.org.

المصدر: Epigenetics & chromatin [Epigenetics Chromatin] 2020 Oct 23; Vol. 13 (1), pp. 44. Date of Electronic Publication: 2020 Oct 23.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 101471619 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-8935 (Electronic) Linking ISSN: 17568935 NLM ISO Abbreviation: Epigenetics Chromatin Subsets: MEDLINE

مواضيع طبية MeSH: DNA Methylation* , Gene Expression Regulation, Neoplastic* , Histone Code*, CCAAT-Enhancer-Binding Proteins/*metabolism , Ubiquitin-Protein Ligases/*metabolism, CCAAT-Enhancer-Binding Proteins/chemistry ; Epigenesis, Genetic ; HCT116 Cells ; HeLa Cells ; Histones/chemistry ; Histones/metabolism ; Humans ; Lysine/metabolism ; Methylation ; Protein Processing, Post-Translational ; Tudor Domain ; Ubiquitin-Protein Ligases/chemistry

المؤلفون: Kong X; The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Chen J; Department of Gastroenterology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province 430030, China; State Key Laboratory of Cancer Biology, National Clinical Research Center for Digestive Diseases and Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xi'an, Shaanxi Province 710032, China., Xie W; The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Brown SM; The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Cai Y; The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Wu K; State Key Laboratory of Cancer Biology, National Clinical Research Center for Digestive Diseases and Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xi'an, Shaanxi Province 710032, China., Fan D; State Key Laboratory of Cancer Biology, National Clinical Research Center for Digestive Diseases and Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xi'an, Shaanxi Province 710032, China., Nie Y; State Key Laboratory of Cancer Biology, National Clinical Research Center for Digestive Diseases and Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xi'an, Shaanxi Province 710032, China., Yegnasubramanian S; The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Tiedemann RL; Center for Epigenetics, Van Andel Research Institute, Grand Rapids, MI 49503, USA., Tao Y; The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Chiu Yen RW; The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Topper MJ; The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Zahnow CA; The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Easwaran H; The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Rothbart SB; Center for Epigenetics, Van Andel Research Institute, Grand Rapids, MI 49503, USA. Electronic address: scott.rothbart@vai.org., Xia L; Department of Gastroenterology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province 430030, China; State Key Laboratory of Cancer Biology, National Clinical Research Center for Digestive Diseases and Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xi'an, Shaanxi Province 710032, China. Electronic address: xialimin@tjh.tjmu.edu.cn., Baylin SB; The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA; Center for Epigenetics, Van Andel Research Institute, Grand Rapids, MI 49503, USA. Electronic address: sbaylin@jhmi.edu.

المصدر: Cancer cell [Cancer Cell] 2019 Apr 15; Vol. 35 (4), pp. 633-648.e7. Date of Electronic Publication: 2019 Apr 04.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101130617 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-3686 (Electronic) Linking ISSN: 15356108 NLM ISO Abbreviation: Cancer Cell Subsets: MEDLINE

مواضيع طبية MeSH: DNA Methylation* , Epigenesis, Genetic*, CCAAT-Enhancer-Binding Proteins/*metabolism , Colorectal Neoplasms/*enzymology , Ubiquitin-Protein Ligases/*metabolism, Animals ; CCAAT-Enhancer-Binding Proteins/genetics ; Caco-2 Cells ; Colorectal Neoplasms/genetics ; Colorectal Neoplasms/metabolism ; Colorectal Neoplasms/pathology ; CpG Islands ; Female ; Gene Expression Regulation, Neoplastic ; HCT116 Cells ; HT29 Cells ; Histones/genetics ; Histones/metabolism ; Humans ; Male ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; Mice, Inbred NOD ; Mice, Nude ; Mice, SCID ; Mutation ; Neoplasm Metastasis ; PHD Zinc Fingers ; Prognosis ; Time Factors ; Ubiquitin-Protein Ligases/genetics