المؤلفون: Sandra Harjuhaahto, Tiina S. Rasila, Svetlana M. Molchanova, Rosa Woldegebriel, Jouni Kvist, Svetlana Konovalova, Markus T. Sainio, Jana Pennonen, Rubén Torregrosa-Muñumer, Hazem Ibrahim, Timo Otonkoski, Tomi Taira, Emil Ylikallio, Henna Tyynismaa

المصدر: Neurobiology of Disease, Vol 141, Iss , Pp 104940- (2020)

مصطلحات موضوعية: CHCHD2, CHCHD10, Induced pluripotent stem cell, Motor neuron differentiation, CMT2, SMAJ, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0969996120302151; https://doaj.org/toc/1095-953X

URL الوصول: https://doaj.org/article/7dd3bc2f74c846f5b352a344121de51b

المؤلفون: Caj Haglund, Leif C. Andersson, Tuomas Kaprio, Ines Beilmann-Lehtonen, Alexander M. Lindström, Harri Mustonen, Olga Saavalainen, Tiina S Rasila

المساهمون: Department of Surgery, Clinicum, CAN-PRO - Translational Cancer Medicine Program, Department of Pathology, HUSLAB, HUS Diagnostic Center, STEMM - Stem Cells and Metabolism Research Program, Medicum, IV kirurgian klinikka, HUS Abdominal Center, II kirurgian klinikka

المصدر: BMC Gastroenterology, Vol 21, Iss 1, Pp 1-8 (2021)
BMC Gastroenterology

مصطلحات موضوعية: Oncology, medicine.medical_specialty, Astroprincin, Colorectal cancer, medicine.medical_treatment, 3122 Cancers, RC799-869, GUIDELINES, COLORECTAL-CANCER, Tissue microarray, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, medicine, Adjuvant therapy, Biomarkers, Tumor, Humans, Stage (cooking), FAM171A1, 030304 developmental biology, 0303 health sciences, business.industry, Research, Gastroenterology, Proteins, General Medicine, Hepatology, Diseases of the digestive system. Gastroenterology, medicine.disease, Prognosis, Immunohistochemistry, 3. Good health, Colon cancer, 030220 oncology & carcinogenesis, 3121 General medicine, internal medicine and other clinical medicine, Cancer cell, Colonic Neoplasms, business, Adjuvant

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae43cc057c5562aa5417fbf77fb9ff49
https://doaj.org/article/390917599c12470aacee50ffa6e976a8

المؤلفون: Petri Lankila, Hesham Attalla, Caj Haglund, Tiina S Rasila, Erkki Hölttä, Olga Saavalainen, Leif C. Andersson

المصدر: The American Journal of Pathology. 189:177-189

مصطلحات موضوعية: 0301 basic medicine, Matrigel, Chemistry, Cell, HEK 293 cells, Transfection, 3T3 cells, 3. Good health, Pathology and Forensic Medicine, Cell biology, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, medicine.anatomical_structure, Cell culture, 030220 oncology & carcinogenesis, medicine, Cytoskeleton, Actin

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::15f32fcf39334d3854a3bbd4077b21ce
https://doi.org/10.1016/j.ajpath.2018.09.006

المؤلفون: Jana Pennonen, Markus T. Sainio, Svetlana M. Molchanova, Sandra Harjuhaahto, Jouni Kvist, Henna Tyynismaa, Tomi Taira, Emil Ylikallio, Hazem Ibrahim, Tiina S Rasila, Timo Otonkoski, Rubén Torregrosa-Muñumer, Svetlana Konovalova, Rosa Woldegebriel

المساهمون: Research Programs Unit, STEMM - Stem Cells and Metabolism Research Program, Faculty of Medicine, University of Helsinki, Molecular and Integrative Biosciences Research Programme, Faculty of Biological and Environmental Sciences, Centre of Excellence in Stem Cell Metabolism, Henna Tyynismaa / Principal Investigator, Helsinki One Health (HOH), HUS Children and Adolescents, Timo Pyry Juhani Otonkoski / Principal Investigator, Synaptic Plasticity and Neuronal Synchronization, Veterinary Biosciences, Tomi Taira / Principal Investigator, Neuroscience Center, Clinicum, HUS Neurocenter, Department of Neurosciences, Neurologian yksikkö, Helsinki University Hospital Area, Department of Medical and Clinical Genetics, Staff Services, Helsinki Institute of Life Science HiLIFE, Basal ganglia circuits

المصدر: Neurobiology of Disease, Vol 141, Iss, Pp 104940-(2020)

مصطلحات موضوعية: 0301 basic medicine, Parkinson's disease, POTENTIATION, ENERGY-METABOLISM, Mitochondrion, AMYOTROPHIC-LATERAL-SCLEROSIS, 3124 Neurology and psychiatry, Membrane Potentials, GLUTAMATE, 0302 clinical medicine, Amyotrophic lateral sclerosis, Induced pluripotent stem cell, Motor Neurons, CMT2, Glutamate receptor, Long-term potentiation, Cell Differentiation, Parkinson Disease, RNA sequencing, Mitochondria, DNA-Binding Proteins, RECEPTORS, medicine.anatomical_structure, Neurology, PLURIPOTENT STEM-CELLS, CHCHD2, Induced Pluripotent Stem Cells, DPP6, Biology, lcsh:RC321-571, Mitochondrial Proteins, 03 medical and health sciences, medicine, Humans, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, CRISPR/Cas9, RELEASE, MUTATIONS, Amyotrophic Lateral Sclerosis, Motor neuron differentiation, 3112 Neurosciences, Spinal muscular atrophy, Motor neuron, medicine.disease, 030104 developmental biology, CHCHD10, SMAJ, Synapses, ALS, Transcriptome, Neuroscience, 030217 neurology & neurosurgery, Transcription Factors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::191057f2ef982386dd6e451124a5528c
http://hdl.handle.net/10138/317778

المؤلفون: Tiina S Rasila, Mauno Vihinen, Lars Paulin, Saija Haapa-Paananen, Harri Savilahti

المصدر: PLoS ONE, Vol 7, Iss 5, p e37922 (2012)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC3362531?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/d5d2a6fd8b7347a3b833293492b866c2

المؤلفون: Sandra Harjuhaahto, Henna Tyynismaa, Jana Pennonen, Tomi Taira, Hazem Ibrahim, Markus T. Sainio, Svetlana M. Molchanova, Emil Ylikallio, Tiina S Rasila, Jouni Kvist, Timo Otonkoski, Svetlana Konovalova, Rosa Woldegebriel

مصطلحات موضوعية: 0303 health sciences, Mitochondrial intermembrane space, Spinal muscular atrophy, Motor neuron, Biology, medicine.disease, Transcriptome, 03 medical and health sciences, 0302 clinical medicine, medicine.anatomical_structure, Gene expression, medicine, Amyotrophic lateral sclerosis, Gene, Neuroscience, 030217 neurology & neurosurgery, Function (biology), 030304 developmental biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb243d187a42916be1085a7bf5882bf1

المؤلفون: Anu Salminen, Saija Kiljunen, Maria Pajunen, Harri Savilahti, Elsi Pulkkinen, Saija Haapa-Paananen, Mauno Vihinen, Lars Paulin, Tiina S Rasila, Phoebe A. Rice

المساهمون: Medicum, Research Programs Unit, Glycoscience Group, Biosciences, Institute of Biotechnology

المصدر: Nucleic Acids Research

مصطلحات موضوعية: Models, Molecular, 0301 basic medicine, Transposable element, STRUCTURAL BASIS, genetic structures, DNA TRANSPOSITION COMPLEXES, Transposases, RECOMBINATION, Computational biology, Biology, medicine.disease_cause, Genome, Genome engineering, Transposition (music), Mice, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, MUTAGENESIS STRATEGY, PHAGE-MU, Genetics, medicine, Animals, Cells, Cultured, Transposase, Mutation, Nucleic Acid Enzymes, ta1184, ta1182, RECOGNITION, IN-VITRO, BACTERIOPHAGE-MU, 030104 developmental biology, Amino Acid Substitution, chemistry, STRAND TRANSFER, DNA Transposable Elements, 1182 Biochemistry, cell and molecular biology, ELECTROPORATION, Bacteriophage Mu, Genetic Engineering, 030217 neurology & neurosurgery, DNA

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::633c587de09526a4cfe4b478ea758728
http://hdl.handle.net/10138/236500

المؤلفون: Jaana Hagström, Caj Haglund, Leif C. Andersson, Petri Lankila, Tuomas Kaprio, Tiina S Rasila, Harri Mustonen

المساهمون: Department of Surgery, Clinicum, Research Programs Unit, Translational Cancer Biology (TCB) Research Programme, STEMM - Stem Cells and Metabolism Research Program, Department of Pathology, University of Helsinki, Medicum, HUSLAB, II kirurgian klinikka, Leif C. Andersson Research Group, HUS Head and Neck Center, HUS Abdominal Center

المصدر: PLoS ONE, Vol 14, Iss 2, p e0211564 (2019)
PLoS ONE

مصطلحات موضوعية: Male, 0301 basic medicine, Carboxy-Lyases, Colorectal cancer, Exosomes, Metastasis, Ornithine decarboxylase, 0302 clinical medicine, Medicine and Health Sciences, Multidisciplinary, Invasive Tumors, Intracellular vesicle, Middle Aged, Prognosis, Immunohistochemistry, Phenotype, 3. Good health, Oncology, 030220 oncology & carcinogenesis, Medicine, Female, Cellular Structures and Organelles, Anatomy, Colorectal Neoplasms, HT29 Cells, Research Article, EXPRESSION, Histology, Colon, Science, Biology, Research and Analysis Methods, 03 medical and health sciences, Diagnostic Medicine, medicine, Humans, Secretion, Vesicles, Immunohistochemistry Techniques, Survival rate, Aged, Colorectal Cancer, RAB27A, Cancers and Neoplasms, Biology and Life Sciences, Cell Biology, medicine.disease, Survival Analysis, GENE, Histochemistry and Cytochemistry Techniques, Gastrointestinal Tract, 030104 developmental biology, CELLS, METASTASIS, Immunologic Techniques, Cancer research, 1182 Biochemistry, cell and molecular biology, 3111 Biomedicine, Digestive System

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d11f232f0c19721c53d41b74609f0fbc
https://doi.org/10.1371/journal.pone.0211564

المؤلفون: Alexandra Lehtonen, Tiina S Rasila, Laura Mäkitie, Caj Haglund, Leif C. Andersson, Kristiina Kanerva

المساهمون: Medicum, Department of Pathology, Department of Anatomy, Clinicum, Translational Cancer Biology (TCB) Research Programme, Department of Surgery, II kirurgian klinikka, Research Programs Unit, Leif C. Andersson Research Group

المصدر: PLoS ONE, Vol 11, Iss 3, p e0151175 (2016)
PLoS ONE

مصطلحات موضوعية: Male, 0301 basic medicine, Physiology, Carboxy-Lyases, Immunofluorescence, lcsh:Medicine, Enteroendocrine cell, Biochemistry, Epithelium, Ornithine decarboxylase, H(+)-K(+)-Exchanging ATPase, 0302 clinical medicine, Animal Cells, Immune Physiology, Testis, Medicine and Health Sciences, Polyamines, lcsh:Science, Lung, INTRACELLULAR VESICLE TRAFFICKING, Ornithine decarboxylase antizyme, Staining, Regulation of gene expression, Immune System Proteins, Multidisciplinary, Cell Staining, Brain, Immunohistochemistry, 3. Good health, Cell biology, ALZHEIMERS-DISEASE, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Cellular Structures and Organelles, Anatomy, Cellular Types, Research Article, Enteroendocrine Cells, Immunology, Biology, Research and Analysis Methods, Antibodies, 03 medical and health sciences, Exocrine Glands, medicine, Humans, Secretion, Vesicles, RNA, Messenger, Immunoassays, Immunohistochemistry Techniques, Cytoplasmic Staining, REGULATORS, ORNITHINE-DECARBOXYLASE PARALOGUE, Cellular Vesicle, lcsh:R, Biology and Life Sciences, Proteins, Epithelial Cells, Cell Biology, GENE, Molecular biology, Histochemistry and Cytochemistry Techniques, Biological Tissue, 030104 developmental biology, Gene Expression Regulation, Specimen Preparation and Treatment, Gastric Mucosa, Immunologic Techniques, Macula densa, lcsh:Q, 3111 Biomedicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2514282a96ccc60b0c0da1bdab1ccfa7
http://europepmc.org/articles/PMC4786150?pdf=render

المؤلفون: Harri Savilahti, Mauno Vihinen, Tiina S Rasila, Lars Paulin, Saija Haapa-Paananen

المساهمون: Institute of Biotechnology, Biolääketieteellisen teknologian yksikkö - Institute of Biomedical Technology, University of Tampere

المصدر: PLoS ONE; 7(5), no e37922 (2012)
Rasila, T S, Vihinen, M, Paulin, L, Haapa-Paananen, S & Savilahti, H 2012, ' Flexibility in mua transposase family protein structures : Functional mapping with scanning mutagenesis and sequence alignment of protein homologues ', PLoS ONE, vol. 7, no. 5, e37922 . https://doi.org/10.1371/journal.pone.0037922
PLoS ONE, Vol 7, Iss 5, p e37922 (2012)
PLoS ONE

مصطلحات موضوعية: Macromolecular Assemblies, Models, Molecular, Genetic Screens, Applied Microbiology, Transposases, lcsh:Medicine, Biochemistry, chemistry.chemical_compound, Protein structure, Nucleic Acids, Lääketieteen bioteknologia - Medical biotechnology, lcsh:Science, Peptide sequence, Transposase, Genetics, 0303 health sciences, Multidisciplinary, biology, 030302 biochemistry & molecular biology, Basic Medicine, Enzymes, Integrase, Research Article, Biotechnology, Transposable element, Molecular Sequence Data, Protein domain, education, Bioengineering, Sequence alignment, Microbiology, Molecular Genetics, Structure-Activity Relationship, 03 medical and health sciences, Genetic Mutation, Virology, Amino Acid Sequence, Biology, 030304 developmental biology, Sequence Homology, Amino Acid, ta1184, lcsh:R, Proteins, Computational Biology, Protein Structure, Tertiary, Mutagenesis, Insertional, chemistry, Mutagenesis, Enzyme Structure, Biocatalysis, biology.protein, lcsh:Q, Sequence Alignment, DNA

وصف الملف: application/pdf; fulltext

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c361be21eba21234924dfc1e40c675d
https://lup.lub.lu.se/record/2890683