المؤلفون: Magnus Nilsson, Magdalena Rhedin, Ramon Hendrickx, Susanne Berglund, Antonio Piras, Parmis Blomgran, Anders Cavallin, Mia Collins, Göran Dahl, Bilel Dekkak, Therese Ericsson, Niklas Hagberg, Ann Aurell Holmberg, Agnes Leffler, Anders J Lundqvist, Thomais Markou, James Pinkerton, Lars Rönnblom, Stacey Siu, Vanessa Taylor, Tiiu Wennberg, Dimitrios Zervas, Arian D J Laurence, Suman Mitra, Maria G Belvisi, Mark Birrell, Annika Borde

المصدر: Drug Design, Development and Therapy. 16:2901-2917

مصطلحات موضوعية: Pharmacology, Drug Design, Development and Therapy, Ovalbumin, STAT, Respiratory Medicine and Allergy, Pharmaceutical Science, Janus Kinase 1, Asthma, Rats, JAK, Drug Discovery, Animals, Cytokines, Humans, Janus Kinase Inhibitors, AZD4604, AZD0449, Lung, Signal Transduction, Lungmedicin och allergi

وصف الملف: application/pdf; text/html

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e0c74bc776adaba8bf5ad2a70652436
https://doi.org/10.2147/dddt.s354291

المؤلفون: Christian Tyrchan, Anna-Pia Palmgren, Hui-Fang Amy Chang, Yunhua Chen, Victoria Ullah, Karin Björhall, Annika Westin Eriksson, Rebecca Fransson, Mickael Mogemark, Tiiu Wennberg, Shuchun Zhao, Bold Peter, Linda Fredlund, Matthew Thomas, Eva Lamm Bergström, Nils Pemberton, Ulf Börjesson, Reed W. Smith, Mikael Brűlls, Johan Carlsson, Britt-Marie Fihn, Linda Öster, Mio Rodrigo Blomqvist, Hongbin Ge, Antonios Nikitidis, Wenzhen Yang, Anders Eriksson, Haijuan Huang, Sarah Lever, Perry Matthew, Kostas Karabelas, Helena Lindmark, Jens Petersen

المصدر: Journal of medicinal chemistry. 64(12)

مصطلحات موضوعية: Male, Class I Phosphatidylinositol 3-Kinases, Ovalbumin, High selectivity, Pharmacology, Crystallography, X-Ray, 01 natural sciences, 03 medical and health sciences, Phosphatidylinositol 3-Kinases, Structure-Activity Relationship, Rats, Inbred BN, Drug Discovery, medicine, Asthmatic patient, Potency, Structure–activity relationship, Animals, Class Ib Phosphatidylinositol 3-Kinase, Humans, Short duration, Protein Kinase Inhibitors, 030304 developmental biology, Asthma, 0303 health sciences, Sulfonamides, biology, Inhalation, Molecular Structure, Chemistry, medicine.disease, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Thiazoles, biology.protein, Leukocytes, Mononuclear, Molecular Medicine, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f1afe7cc480e1edf37ab207774eb9ff
https://pubmed.ncbi.nlm.nih.gov/34080862