المؤلفون: Lilia Falkenstern, Victoria Georgi, Stefanie Bunse, Volker Badock, Manfred Husemann, Ulrike Roehn, Timo Stellfeld, Mark Fitzgerald, Steven Ferrara, Detlef Stöckigt, Carlo Stresemann, Ingo V. Hartung, Amaury Fernández-Montalván

المصدر: Scientific Reports, Vol 14, Iss 1, Pp 1-21 (2024)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2045-2322

URL الوصول: https://doaj.org/article/86f7032f806147479748eda7c74b8341

المؤلفون: Douglas L, Orsi, Elisabeth, Pook, Nico, Bräuer, Anders, Friberg, Philip, Lienau, Christopher T, Lemke, Timo, Stellfeld, Ulf, Brüggemeier, Vera, Pütter, Hanna, Meyer, Maria, Baco, Stephanie, Tang, Andrew D, Cherniack, Lindsay, Westlake, Samantha A, Bender, Mustafa, Kocak, Craig A, Strathdee, Matthew, Meyerson, Knut, Eis, Jonathan T, Goldstein

المصدر: Journal of medicinal chemistry. 65(21)

مصطلحات موضوعية: PPAR gamma, Ligands

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::ae813451ab4026cd308dc1142c4ed2b6
https://pubmed.ncbi.nlm.nih.gov/36542814

المؤلفون: Douglas L. Orsi, Elisabeth Pook, Nico Bräuer, Anders Friberg, Philip Lienau, Christopher T. Lemke, Timo Stellfeld, Ulf Brüggemeier, Vera Pütter, Hanna Meyer, Maria Baco, Stephanie Tang, Andrew D. Cherniack, Lindsay Westlake, Samantha A. Bender, Mustafa Kocak, Craig A. Strathdee, Matthew Meyerson, Knut Eis, Jonathan T. Goldstein

المصدر: Journal of Medicinal Chemistry. 65:14843-14863

مصطلحات موضوعية: Drug Discovery, Molecular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::bcec82278b2a513b7653d5a4ef4822cb
https://doi.org/10.1021/acs.jmedchem.2c01379

المؤلفون: Douglas L. Orsi, Steven J. Ferrara, Stephan Siegel, Anders Friberg, Léa Bouché, Elisabeth Pook, Philip Lienau, Joseph P. Bluck, Christopher T. Lemke, Gizem Akcay, Timo Stellfeld, Hanna Meyer, Vera Pütter, Simon J. Holton, Daniel Korr, Isabel Jerchel-Furau, Constantia Pantelidou, Craig A. Strathdee, Matthew Meyerson, Knut Eis, Jonathan T. Goldstein

المصدر: Bioorganic & medicinal chemistry 78, 117130 (2023). doi:10.1016/j.bmc.2022.117130

مصطلحات موضوعية: Organic Chemistry, Clinical Biochemistry, Drug Discovery, Pharmaceutical Science, Molecular Medicine, ddc:610, Molecular Biology, Biochemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc8a065063af626237bd6ead93ee15d7
https://bib-pubdb1.desy.de/record/491342

المؤلفون: Douglas L. Orsi, Elisabeth Pook, Nico Bräuer, Anders Friberg, Philip Lienau, Christopher T. Lemke, Timo Stellfeld, Ulf Brüggemeier, Vera Pütter, Hanna Meyer, Maria Baco, Stephanie Tang, Andrew D. Cherniack, Lindsay Westlake, Samantha A. Bender, Mustafa Kocak, Craig A. Strathdee, Matthew Meyerson, Knut Eis, Jonathan T. Goldstein

المصدر: Journal of Medicinal Chemistry. 66:1082-1082

مصطلحات موضوعية: Drug Discovery, Molecular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ec4cea163f1d6c31ece521e358ffd5a2
https://doi.org/10.1021/acs.jmedchem.2c02002

المؤلفون: Tobias Thaler, Elisabeth Kersten, Hannah JÖRIßEN, Chantal Fürstner, Sonja Anlauf, Mark Meininghaus, Kersten Matthias Gericke, Lisa Dietz, Dirk Schneider, Hartmut Beck, Virginia Marossek, Carsten Terjung, Johanna Anlahr, Daniel Meibom, Uwe Münster, Thomas Buyck, Raimund Kast, Kai Lovis, Timo Stellfeld, Guillaume Levilain, Michaela Bairlein, Clemens-Jeremias Von Bühler

المصدر: Journal of Medicinal Chemistry. 63:11639-11662

مصطلحات موضوعية: Male, Prostaglandin F receptor, Receptors, Prostaglandin, Administration, Oral, Pharmacology, 01 natural sciences, Mice, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, Idiopathic pulmonary fibrosis, In vivo, Drug Discovery, medicine, Animals, Humans, Rats, Wistar, Receptor, Lung, 030304 developmental biology, 0303 health sciences, Molecular Structure, Antagonist, Pirfenidone, respiratory system, medicine.disease, Idiopathic Pulmonary Fibrosis, Rats, respiratory tract diseases, 0104 chemical sciences, Disease Models, Animal, 010404 medicinal & biomolecular chemistry, medicine.anatomical_structure, chemistry, Quinolines, Molecular Medicine, Nintedanib, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb3bcb4904153e431b637e901e8f4428
https://doi.org/10.1021/acs.jmedchem.0c00834

المؤلفون: Cheryl H. Arrowsmith, Cora Scholten, Léa Bouché, Masoud Vedadi, Mathew Sutherland, Ingo Hartung, Alice Li, Vijayaratnam Santhakumar, Dimitrios Panagopoulos, Magdalena M. Szewczyk, Fengling Li, Robert Britton, Timo Stellfeld, Holger Steuber, Dalia Barsyte, David Smil, Anissa Kaghad

المصدر: ChemMedChem 16(7), 1116-1125 (2021). doi:10.1002/cmdc.202100018

مصطلحات موضوعية: Protein-Arginine N-Methyltransferases, Indoles, Arginine, Antineoplastic Agents, 01 natural sciences, Biochemistry, Structure-Activity Relationship, Histone H3, Non-histone protein, Neoplasms, Drug Discovery, medicine, Humans, Transferase, ddc:610, General Pharmacology, Toxicology and Pharmaceutics, Enzyme Inhibitors, Pharmacology, Alanine, Dose-Response Relationship, Drug, Molecular Structure, Chemotype, 010405 organic chemistry, Chemistry, Organic Chemistry, Rational design, Cancer, Methylation, medicine.disease, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, HEK293 Cells, Drug Design, Molecular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f59892e7b4f1f6e1fd9df5173926932c
https://doi.org/10.1101/2020.11.17.387233

المؤلفون: Claudia Merz, Marcus Bauser, Martin Michels, Ashley Eheim, David T. Scadden, Henrik Seidel, Ralf Lesche, Timo Stellfeld, Hanna Meyer, Pascale Lejeune, Thomas Mueller, Detlef Stoeckigt, David B. Sykes, Steven James Ferrara, Sven Christian, Andrea Haegebarth, Judith Guenther, Andreas Janzer, Katja Zimmermann, Sherif El Sheikh, Stefan Gradl, Michael Bruening

المصدر: Cancer Research. 78:DDT02-04

مصطلحات موضوعية: 0301 basic medicine, Acute promyelocytic leukemia, Cancer Research, Acute leukemia, Myeloid, business.industry, Myeloid leukemia, Cancer, medicine.disease, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, medicine.anatomical_structure, Oncology, Differentiation therapy, 030220 oncology & carcinogenesis, Cancer research, Dihydroorotate dehydrogenase, medicine, Cytarabine, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::810e228e308047a51f2ef7b9122f3063
https://doi.org/10.1158/1538-7445.am2018-ddt02-04

المؤلفون: Katja Zimmermann, Henrik Seidel, Vera Puetter, Sherif El Sheikh, Steven James Ferrara, Stefan Gradl, Claudia Merz, Anders Friberg, Sven Christian, Andrea Haegebarth, Thomas Mueller, Ashley Eheim, Timo Stellfeld, David T. Scadden, Marcus Bauser, Duy Nguyen, Michael Niehues, Martina Schaefer, Michael Bruening, Martin Michels, Judith Guenther, Knut Eis, Detlef Stoeckigt, Hanna Meyer, Pascal Lejeune, Andreas Janzer, Han-Jie Zhou, David B. Sykes, Michael Kroeber

المصدر: Cancer Research. 79:2-2

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Myeloid, Phenotypic screening, Cancer, Biological activity, Biology, medicine.disease, 03 medical and health sciences, Leukemia, 030104 developmental biology, 0302 clinical medicine, medicine.anatomical_structure, Oncology, In vivo, 030220 oncology & carcinogenesis, medicine, Cancer research, Dihydroorotate dehydrogenase, Structure–activity relationship

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e6ee917949e8111944b8c7f5491d2229
https://doi.org/10.1158/1538-7445.am2019-2

المؤلفون: Ludger Dinkelborg, Roger Schibli, Markus Reiher, Timo Stellfeld, Carmen J. Müller, Stefanie D. Krämer, Svetlana V. Selivanova, Simon M. Ametamey, Keith Graham, Lukas O. Dialer, Adrienne Müller

المصدر: Journal of Medicinal Chemistry. 56:7552-7563

مصطلحات موضوعية: Male, Fluorine Radioisotopes, Biodistribution, Silicon, Mice, Nude, chemistry.chemical_element, Conjugated system, Mice, Structure-Activity Relationship, chemistry.chemical_compound, Drug Stability, In vivo, Drug Discovery, Animals, Humans, Tissue Distribution, chemistry.chemical_classification, Hydrolysis, Biomolecule, Bombesin, Neoplasms, Experimental, Silanes, Combinatorial chemistry, Receptors, Bombesin, chemistry, Isotope Labeling, Positron-Emission Tomography, Heterografts, Quantum Theory, Molecular Medicine, Radiopharmaceuticals, Peptides, Hydrophobic and Hydrophilic Interactions, Linker, Conjugate

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14987e3eb91210e89a3a62b4dac37df6
https://doi.org/10.1021/jm400857f