المؤلفون: Cemal Erdem, Adrian V Lee, D Lansing Taylor, Timothy R Lezon

المصدر: PLoS Computational Biology, Vol 17, Iss 6, p e1009125 (2021)

مصطلحات موضوعية: Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1553-734X; https://doaj.org/toc/1553-7358

URL الوصول: https://doaj.org/article/5a50932ee04e4320af6e668981cb0eb3

المؤلفون: Ron Nafshi, Timothy R. Lezon

المصدر: Frontiers in Bioinformatics. 1

مصطلحات موضوعية: Drug, Training set, Matrix completion, Computer science, business.industry, Drug discovery, media_common.quotation_subject, Phenotypic screening, General Medicine, Drug resistance, Machine learning, computer.software_genre, Matrix decomposition, Probabilistic matrix factorization, Drug development, Pairwise comparison, Artificial intelligence, Cancer cell lines, business, computer, media_common

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c29058ab27599789fdcc6320af395625
https://doi.org/10.3389/fbinf.2021.708815

المؤلفون: D. Lansing Taylor, Adrian V. Lee, Cemal Erdem, Timothy R. Lezon

المصدر: PLoS Computational Biology, Vol 17, Iss 6, p e1009125 (2021)
PLoS Computational Biology

مصطلحات موضوعية: 0301 basic medicine, MAPK/ERK pathway, Cell signaling, Physiology, Genes, BRCA2, Genes, BRCA1, Stimulation, Signal transduction, Biochemistry, Receptor, IGF Type 1, Phosphatidylinositol 3-Kinases, Endocrinology, 0302 clinical medicine, Insulin Signaling Cascade, Breast Tumors, Medicine and Health Sciences, Insulin, Post-Translational Modification, Phosphorylation, Insulin-Like Growth Factor I, Biology (General), Phosphoinositide-3 Kinase Inhibitors, Protein Kinase Signaling Cascade, Ecology, Kinase, Signaling cascades, Cell biology, Oncology, Computational Theory and Mathematics, 030220 oncology & carcinogenesis, Modeling and Simulation, Ribosomal protein s6, MCF-7 Cells, Female, hormones, hormone substitutes, and hormone antagonists, Research Article, endocrine system, MAPK signaling cascades, MAP Kinase Signaling System, QH301-705.5, Breast Neoplasms, Biology, Models, Biological, 03 medical and health sciences, Cellular and Molecular Neuroscience, Antigens, CD, Cell Line, Tumor, Breast Cancer, Genetics, Humans, Computer Simulation, Kinase activity, Molecular Biology, Protein kinase B, Ecology, Evolution, Behavior and Systematics, Insulin-like growth factor 1 receptor, Diabetic Endocrinology, Endocrine Physiology, Ribosomal Protein S6 Kinases, Insulin Signaling, Biology and Life Sciences, Cancers and Neoplasms, Proteins, Computational Biology, Hormones, Receptor, Insulin, Insulin receptor, 030104 developmental biology, biology.protein, Proto-Oncogene Proteins c-akt

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cfcaaa11224b90249abefe0b1cf5261
https://doaj.org/article/5a50932ee04e4320af6e668981cb0eb3

المؤلفون: Albert H Gough, Ning Chen, Tong Ying Shun, Timothy R Lezon, Robert C Boltz, Celeste E Reese, Jacob Wagner, Lawrence A Vernetti, Jennifer R Grandis, Adrian V Lee, Andrew M Stern, Mark E Schurdak, D Lansing Taylor

المصدر: PLoS ONE, Vol 9, Iss 7, p e102678 (2014)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC4103836?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/073440165ed34f8b8cced8d70b8f685a

المؤلفون: D L Taylor, Adrian V. Lee, Cemal Erdem, Timothy R. Lezon

مصطلحات موضوعية: MAPK/ERK pathway, Insulin receptor, Insulin receptor substrate, biology.protein, Kinase activity, Biology, Signal transduction, Receptor, Protein kinase B, Insulin-like growth factor 1 receptor, Cell biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::6b4052410ea3f7c404798e93bcde0125
https://doi.org/10.1101/2020.10.22.349647

المؤلفون: Daniel M Spagnolo, Rekha Gyanchandani, Yousef Al-Kofahi, Andrew M Stern, Timothy R Lezon, Albert Gough, Dan E Meyer, Fiona Ginty, Brion Sarachan, Jeffrey Fine, Adrian V Lee, D Lansing Taylor, S Chakra Chennubhotla

المصدر: Journal of Pathology Informatics, Vol 7, Iss 1, Pp 47-47 (2016)

مصطلحات موضوعية: Computational pathology, multiplexed immunofluorescence, pointwise mutual information, tumor heterogeneity, tumor microenvironment, Computer applications to medicine. Medical informatics, R858-859.7, Pathology, RB1-214

وصف الملف: electronic resource

Relation: http://www.jpathinformatics.org/article.asp?issn=2153-3539;year=2016;volume=7;issue=1;spage=47;epage=47;aulast=Spagnolo; https://doaj.org/toc/2153-3539

URL الوصول: https://doaj.org/article/0133c569b3f04299ad5b8fe46e6286f6

المؤلفون: Diane L. Carlisle, Robert M. Friedlander, Anton Simeonov, Hongchun Li, Murat Can Cobanoglu, Fen Pei, Mark J. Henderson, Andrew M. Stern, Tongying Shun, Timothy R. Lezon, Seyed H Mousavi, D. Lansing Taylor, Steve Titus, Lee Apostle Mcdermott, Michael Fioravanti, Prema Iyer, Mark E. Schurdak, Ivet Bahar, Ajit Jadhav

المصدر: Scientific Reports, Vol 7, Iss 1, Pp 1-16 (2017)
Scientific Reports

مصطلحات موضوعية: 0301 basic medicine, Huntingtin, Phenotypic screening, lcsh:Medicine, Biology, Protective Agents, Article, Small Molecule Libraries, 03 medical and health sciences, chemistry.chemical_compound, Mice, Huntington's disease, Chemogenomics, medicine, Animals, lcsh:Science, Neurons, Huntingtin Protein, Multidisciplinary, 030102 biochemistry & molecular biology, Drug discovery, Mechanism (biology), lcsh:R, medicine.disease, Small molecule, Cyclic AMP-Dependent Protein Kinases, 3. Good health, Disease Models, Animal, Drug Combinations, 030104 developmental biology, Huntington Disease, Phenotype, chemistry, Mutation, lcsh:Q, Neuroscience, Systems pharmacology, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e75064ea43dd18201b922d197c80331f
http://link.springer.com/article/10.1038/s41598-017-17378-y

المؤلفون: Fiona Ginty, Adrian V. Lee, Yousef Al-Kofahi, Chakra Chennubhotla, Andrew M. Stern, Peihong Zhu, Albert Gough, D. Lansing Taylor, Daniel Spagnolo, Timothy R. Lezon, Brion Daryl Sarachan

المصدر: Cancer Research. 77:e71-e74

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Computational biology, Biology, Bioinformatics, Multiplexing, Tumor heterogeneity, Article, Genetic Heterogeneity, 03 medical and health sciences, 0302 clinical medicine, Optical imaging, Immune infiltration, Neoplasms, Image Processing, Computer-Assisted, Humans, Segmentation, Interactive visualization, Extramural, Optical Imaging, ComputingMethodologies_PATTERNRECOGNITION, 030104 developmental biology, Workflow, Oncology, Tissue Array Analysis, 030220 oncology & carcinogenesis, Algorithms, Software

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::590a9cb820ab7f1f0400507b241fbeed
https://doi.org/10.1158/0008-5472.can-17-0676

المؤلفون: Timothy R Lezon, Ivet Bahar

المصدر: PLoS Computational Biology, Vol 6, Iss 6, p e1000816 (2010)

مصطلحات موضوعية: Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC2887458?pdf=render; https://doaj.org/toc/1553-734X; https://doaj.org/toc/1553-7358

URL الوصول: https://doaj.org/article/b5641b7addd3488ba021570a337ea460

المؤلفون: Timothy R Lezon, Andrej Sali, Ivet Bahar

المصدر: PLoS Computational Biology, Vol 5, Iss 9, p e1000496 (2009)

مصطلحات موضوعية: Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC2725293?pdf=render; https://doaj.org/toc/1553-734X; https://doaj.org/toc/1553-7358

URL الوصول: https://doaj.org/article/a65ca8ffa1df4100be4d2948e3763232