يعرض 1 - 9 نتائج من 9 نتيجة بحث عن '"Tivel, K L"', وقت الاستعلام: 0.90s تنقيح النتائج
  1. 1
    دورية
    Modulation of plasma protein binding and in vivo liver cell uptake of phosphorothioate oligodeoxynucleotides by cholesterol conjugation.

    المؤلفون: Bijsterbosch, M K, Rump, E T, De Vrueh, R L, Dorland, R, van Veghel, R, Tivel, K L, Biessen, E A, van Berkel, T J, Manoharan, M

    المصدر: Nucleic Acids Research; July 2000, Vol. 28 Issue: 14 p2717-2725, 9p

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  2. 2
    دورية
    Pharmacokinetic properties of several novel oligonucleotide analogs in mice.

    المؤلفون: Crooke, S T, Graham, M J, Zuckerman, J E, Brooks, D, Conklin, B S, Cummins, L L, Greig, M J, Guinosso, C J, Kornbrust, D, Manoharan, M, Sasmor, H M, Schleich, T, Tivel, K L, Griffey, R H

    المصدر: The Journal of Pharmacology and Experimental Therapeutics; May 1996, Vol. 277 Issue: 2 p923-937, 15p

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  3. 3
    دورية
    Inhibition of expression of the multidrug resistance-associated P-glycoprotein of by phosphorothioate and 5' cholesterol-conjugated phosphorothioate antisense oligonucleotides.

    المؤلفون: Alahari, S K, Dean, N M, Fisher, M H, Delong, R, Manoharan, M, Tivel, K L, Juliano, R L

    المصدر: Molecular Pharmacology; October 1996, Vol. 50 Issue: 4 p808-819, 12p

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  4. 4
    دورية
    Synthesis of ^1^4C-radiolabeled oligonucleotides with a novel phosphoramidite reagent

    المؤلفون: Guzaev, A., Boyode, B., Balow, G., Tivel, K. L., Manoharan, M.

    المصدر: Bioorganic & Medicinal Chemistry Letters; 1998, Vol. 8 Issue: 9 p1123-1126, 4p

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  5. 5
    دورية أكاديمية
    ChemInform Abstract: Introduction of a Lipophilic Thioether Tether in the Minor Groove of Nucleic Acids for Antisense Applications.

    المؤلفون: MANOHARAN, M., JOHNSON, L. K., TIVEL, K. L., SPRINGER, R. H., COOK, P. D.

    المصدر: ChemInform; Jul1994, Vol. 25 Issue 27, pno-no, 1p

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  6. 6
    دورية
    A 2'-O-thiol tether in the ribose moiety of nucleic acids for conjugation chemistry

    المؤلفون: Manoharan, M., Tivel, K. L., Ross, B., Cook, P. D.

    المصدر: Gene; 1994, Vol. 149 Issue: 1 p147-147, 1p

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  7. 7
    دورية
    Introduction of a lipophilic thioether tether in the minor groove of nucleic acids for antisense applications

    المؤلفون: Manoharan, M., Johnson, L. K., Tivel, K. L., Springer, R. H.

    المصدر: Bioorganic & Medicinal Chemistry Letters; 1993, Vol. 3 Issue: 12 p2765-2765, 1p

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  8. 8
    دورية أكاديمية
    Synthesis of 14 C-radiolabeled oligonucleotides with a novel phosphoramidite reagent.

    المؤلفون: Guzaev A; Department of Medicinal Chemistry, Isis Pharmaceuticals, Carlsbad, CA 92008., Boyode B, Balow G, Tivel KL, Manoharan M

    المصدر: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 1998 May 05; Vol. 8 (9), pp. 1123-6.

    نوع المنشور: Journal Article

    بيانات الدورية: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print Cited Medium: Print ISSN: 0960-894X (Print) Linking ISSN: 0960894X NLM ISO Abbreviation: Bioorg Med Chem Lett Subsets: MEDLINE

    مواضيع طبية MeSH: Organophosphorus Compounds*, Oligonucleotides/*chemical synthesis , Thymidine/*analogs & derivatives, Carbon Radioisotopes ; Indicators and Reagents ; Isotope Labeling/methods ; Models, Molecular ; Molecular Conformation ; Molecular Structure ; Oligonucleotides/chemistry

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  9. 9
    دورية أكاديمية
    In vivo fate of phosphorothioate antisense oligodeoxynucleotides: predominant uptake by scavenger receptors on endothelial liver cells.

    المؤلفون: Bijsterbosch MK; Division of Biopharmaceutics, Leiden/Amsterdam Center for Drug Research, PO Box 9503, 2300 RA Leiden, The Netherlands., Manoharan M, Rump ET, De Vrueh RL, van Veghel R, Tivel KL, Biessen EA, Bennett CF, Cook PD, van Berkel TJ

    المصدر: Nucleic acids research [Nucleic Acids Res] 1997 Aug 15; Vol. 25 (16), pp. 3290-6.

    نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

    بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Print ISSN: 0305-1048 (Print) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE

    مواضيع طبية MeSH: Membrane Proteins* , Receptors, Lipoprotein*, Liver/*metabolism , Oligonucleotides, Antisense/*metabolism , Receptors, Immunologic/*metabolism , Thionucleotides/*metabolism, Animals ; Endothelium/metabolism ; Intercellular Adhesion Molecule-1/genetics ; Male ; Metabolic Clearance Rate ; Mice ; Polyelectrolytes ; Polymers/metabolism ; Rats ; Rats, Wistar ; Receptors, Scavenger ; Scavenger Receptors, Class B ; Subcellular Fractions/metabolism ; Tissue Distribution

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